Find cheap American Airlines flights to Santiago
ICT — SCL
Nov 7 — Nov 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Leverage Cheapflights for Your Next Trip
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Find American Airlines flight deals to Santiago
Cheapest
Best
Direct
Last-minute
One-way
Cheapest American Airlines flights from USA to SantiagoExplore the most affordable American Airlines flight options available from USA to Santiago. Find the lowest fares with prices last updated on October 8, 2026.
Explore the most affordable American Airlines flight options available from USA to Santiago. Find the lowest fares with prices last updated on October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:23 pm -
1 stop11h 22m
Tue 11/1710:30 pm -
1 stop18h 45m
Deal found 10/4![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:26 pm -
1 stop11h 59m
Sun 12/610:30 pm -
2 stops17h 06m
Deal found 10/8![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:33 pm -
2 stops17h 02m
Tue 11/310:30 pm -
1 stop13h 01m
Deal found 10/7![American Airlines logo]()
$578
Best American Airlines flights from USA to SantiagoDiscover carefully curated American Airlines flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated American Airlines flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:23 pm -
1 stop11h 22m
Tue 11/1710:30 pm -
1 stop18h 45m
Deal found 10/4![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:57 am -
1 stop23h 18m
Fri 3/511:45 pm -
1 stop15h 34m
Deal found 10/4![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:28 pm -
2 stops15h 47m
Sat 12/1210:30 pm -
2 stops15h 20m
Deal found 10/5![American Airlines logo]()
$550
Direct American Airlines flights from USA to SantiagoExplore non-stop American Airlines flight options from USA to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated October 8, 2026.
Explore non-stop American Airlines flight options from USA to Santiago based on user searches, and compare prices and availability for your desired travel dates. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:20 pm -
Nonstop8h 25m
Sun 11/2210:30 pm -
Nonstop8h 30m
Deal found 10/6![American Airlines logo]()
$826
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2711:00 pm -
Nonstop8h 25m
Sun 3/1410:15 pm -
Nonstop8h 45m
Deal found 10/6![American Airlines logo]()
$837
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:00 pm -
Nonstop8h 10m
Tue 11/1010:30 pm -
Nonstop8h 30m
Deal found 10/6![American Airlines logo]()
$857
Last-minute American Airlines flights from USA to SantiagoDiscover last-minute American Airlines flight deals from USA to Santiago. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute American Airlines flight deals from USA to Santiago. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:23 pm -
1 stop11h 22m
Tue 11/1710:30 pm -
1 stop18h 45m
Deal found 10/4![American Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:26 pm -
1 stop11h 59m
Sun 12/610:30 pm -
2 stops17h 06m
Deal found 10/8![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:33 pm -
2 stops17h 02m
Tue 11/310:30 pm -
1 stop13h 01m
Deal found 10/7![American Airlines logo]()
$578
One-way American Airlines flights to SantiagoSearch for one-way American Airlines flight options to Santiago. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way American Airlines flight options to Santiago. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/151:03 pm -
2 stops17h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![American Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/244:26 pm -
1 stop13h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![American Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:25 pm -
1 stop11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$267
Flights to Santiago with American Airlines at a glance
Find detailed information about American Airlines flights from USA to Santiago. Explore the options provided by American Airlines to plan your journey from USA to Santiago. Data last updated October 8, 2026.
Cheapflights Insights
Find cheap American Airlines flights to Santiago
US0-SCL
MIA-SCL
BOS-SCL
MCO-SCL
How long is the flight to Santiago with American Airlines?
On average, American Airlines flights from the United States to Santiago take 10 hours 25 minutes. Flights to Santiago from other popular cities in the United States will vary in length. Below are a few examples of popular routes and their flight times.
American Airlines weekly flight availability to Santiago
The most flights to Santiago operated by American Airlines are scheduled on a Sunday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
When is the best time to book a flight to Santiago with American Airlines?
The best time to book a flight to Santiago with American Airlines is 47 days before departure. On average, fares are higher if you book 85 days before departure.
FAQs about flights to Santiago with American Airlines
Reviews of American Airlines
See what Cheapflights users have to say about their American Airlines experience.
Overview
Reviews
American Airlines
10,000 reviews
Overview
Comfort
7.2
Food
6.4
Boarding
7.4
Entertainment
6.8
Crew
7.9
Recent reviews
10.0
|Sep 2026It was a good experience fast and comfy
8.0
|Sep 2026More organized boarding, actual entertainment screens lol
10.0
|Aug 2026Service Excellent
10.0
|Aug 2026I love everything will fly again thank you 😊
2.0
|Aug 2026Terrible. Will not fly it again. Constant delays. Canceled flight because a pilot didn't show up the AA stated it was weather related. AA is also liars and didn't want to take responsibility or pay. Delayed luggage. Just horrible all the way around. Second time with this. Lost luggage on a previous flight. Back to Delta.
1 out of 3334
Popular American Airlines flights
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Airports nearby
American Airlines
Chile flights
Complete your trip
Flights by cabin class
Flights from SCL
Flights to SCL
Popular Chile flight routes
Popular destinations
Popular flights
Popular routes