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Find cheap American Airlines flights to Santiago

RDU — SCL
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Find American Airlines flight deals to Santiago

Cheapest American Airlines flights from USA to Santiago
Explore the most affordable American Airlines flight options available from USA to Santiago. Find the lowest fares with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:59 pm
LGA
-
SCL
1 stop14h 06m
American Airlines
Tue 9/18:50 pm
SCL
-
LGA
1 stop14h 58m
American Airlines
Deal found 7/27$641
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:25 pm
LGA
-
SCL
1 stop12h 40m
American Airlines
Tue 9/18:50 pm
SCL
-
LGA
1 stop22h 59m
American Airlines
Deal found 7/23$650
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:30 pm
EWR
-
SCL
1 stop12h 35m
American Airlines
Thu 9/38:50 pm
SCL
-
EWR
1 stop19h 49m
American Airlines
Deal found 7/23$650

Flights to Santiago with American Airlines at a glance

Find detailed information about American Airlines flights from USA to Santiago. Explore the options provided by American Airlines to plan your journey from USA to Santiago. Data last updated July 27, 2026.

Popular in

December

Cheapest in

January

Average price

$868

Round-trip from

$617

One-way from

$383
Highest demand for flights to Santiago with American Airlines; 1% potential price increase.
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Best time to find cheap flights to Santiago with American Airlines; 2% potential price drop.
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Average price for flights to Santiago with American Airlines (round-trip).
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American Airlines
  • American Airlines
  • 11/8-11/18
  • 2 total stops
  • 48h 26m total
  • USA to Santiago
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American Airlines
  • American Airlines
  • 9/13
  • Nonstop
  • 8h 10m total
  • USA to Santiago
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Cheapflights Insights

Find cheap American Airlines flights to Santiago

How long is the flight to Santiago with American Airlines?

On average, American Airlines flights from the United States to Santiago take 10 hours 28 minutes. Flights to Santiago from other popular cities in the United States will vary in length. Below are a few examples of popular routes and their flight times.

American Airlines weekly flight availability to Santiago

The most flights to Santiago operated by American Airlines are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

When is the best time to book a flight to Santiago with American Airlines?

The best time to book a flight to Santiago with American Airlines is 47 days before departure. On average, fares are higher if you book 63 days before departure.

FAQs about flights to Santiago with American Airlines

  • Which airport do American Airlines flights arrive at when travelling to Santiago?

    American Airlines flights on this route tend to land at Santiago Arturo Merino Benitez Airport.

  • Is American Airlines the cheapest airline for a flight to Santiago?

    Flight prices will depend on many factors like date, time and cabin class so it is worth comparing flights before booking. Based on Cheapflights data the cheapest average return price for flights to Santiago tends to be with Arajet.

  • Are there alternative airlines other than American Airlines that fly to Santiago?

    LATAM Airlines, Delta and United Airlines all fly to Santiago and offer an alternative to American Airlines.

  • How much is a flight to Santiago with American Airlines?

    The average price for a return flight with American Airlines is $1,007; with a one-way flight around $517.

See more FAQs

Reviews of American Airlines

See what Cheapflights users have to say about their American Airlines experience.
American Airlines
7.1
Good
10,000 reviews
Overview

Crew

7.9

Food

6.4

Comfort

7.2

Boarding

7.5

Entertainment

6.8

Popular American Airlines flights

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