Find cheap American Airlines flights to Key West
RDU — EYW
Aug 26 — Sep 21
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Leverage Cheapflights for Your Next Trip
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Find American Airlines flight deals to Key West
Cheapest
Best
Direct
Last-minute
One-way
Cheapest American Airlines flights from USA to Key WestExplore the most affordable American Airlines flight options available from USA to Key West. Find the lowest fares with prices last updated on July 27, 2026.
Explore the most affordable American Airlines flight options available from USA to Key West. Find the lowest fares with prices last updated on July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:13 am
ATL
- EYW
1 stop3h 55m
American Airlines
Sat 9/51:35 pm
EYW
- ATL
1 stop4h 27m
American Airlines
Deal found 7/26![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:08 pm
ATL
- EYW
1 stop4h 31m
American Airlines
Mon 8/318:09 pm
EYW
- ATL
1 stop3h 46m
American Airlines
Deal found 7/22![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:00 pm
ORD
- EYW
Nonstop3h 19m
American Airlines
Sat 9/54:56 pm
EYW
- ORD
Nonstop3h 52m
American Airlines
Deal found 7/22![American Airlines logo]()
$306
Best American Airlines flights from USA to Key WestDiscover carefully curated American Airlines flight deals from USA to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated American Airlines flight deals from USA to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:00 am
ATL
- EYW
1 stop6h 17m
American Airlines
Fri 9/253:30 pm
EYW
- ATL
1 stop5h 26m
American Airlines
Deal found 7/26![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:30 am
EWR
- EYW
1 stop7h 47m
American Airlines
Wed 9/167:47 pm
EYW
- EWR
1 stop5h 09m
American Airlines
Deal found 7/22![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:38 am
BWI
- EYW
1 stop7h 17m
American Airlines
Tue 9/2911:30 am
EYW
- BWI
1 stop5h 11m
American Airlines
Deal found 7/22![American Airlines logo]()
$319
Direct American Airlines flights from USA to Key WestExplore non-stop American Airlines flight options from USA to Key West based on user searches, and compare prices and availability for your desired travel dates. Data last updated July 27, 2026.
Explore non-stop American Airlines flight options from USA to Key West based on user searches, and compare prices and availability for your desired travel dates. Data last updated July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:00 pm
ORD
- EYW
Nonstop3h 19m
American Airlines
Sat 9/54:56 pm
EYW
- ORD
Nonstop3h 52m
American Airlines
Deal found 7/22![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:50 am
ORD
- EYW
Nonstop3h 25m
American Airlines
Tue 11/176:31 pm
EYW
- ORD
Nonstop3h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:50 am
ORD
- EYW
Nonstop3h 25m
American Airlines
Wed 11/116:21 pm
EYW
- ORD
Nonstop3h 59m
American Airlines
Deal found 7/27![American Airlines logo]()
$319
Last-minute American Airlines flights from USA to Key WestDiscover last-minute American Airlines flight deals from USA to Key West. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute American Airlines flight deals from USA to Key West. Data last updated July 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:13 am
ATL
- EYW
1 stop3h 55m
American Airlines
Sat 9/51:35 pm
EYW
- ATL
1 stop4h 27m
American Airlines
Deal found 7/26![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:08 pm
ATL
- EYW
1 stop4h 31m
American Airlines
Mon 8/318:09 pm
EYW
- ATL
1 stop3h 46m
American Airlines
Deal found 7/22![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:00 pm
ORD
- EYW
Nonstop3h 19m
American Airlines
Sat 9/54:56 pm
EYW
- ORD
Nonstop3h 52m
American Airlines
Deal found 7/22![American Airlines logo]()
$306
One-way American Airlines flights to Key WestSearch for one-way American Airlines flight options to Key West. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way American Airlines flight options to Key West. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:06 am
EWR
- EYW
1 stop4h 59m
American Airlines
Deal found 7/22![American Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am
BOS
- EYW
1 stop8h 16m
American Airlines
Deal found 7/22![American Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:55 am
EWR
- EYW
1 stop7h 08m
American Airlines
Deal found 7/26![American Airlines logo]()
$193
Flights to Key West with American Airlines at a glance
Find detailed information about American Airlines flights from USA to Key West. Explore the options provided by American Airlines to plan your journey from USA to Key West. Data last updated July 27, 2026.
Cheapflights Insights
Find cheap American Airlines flights to Key West
US0-EYW
ORD-EYW
ATL-EYW
EWR-EYW
BOS-EYW
How long is the flight to Key West with American Airlines?
On average, American Airlines flights from the United States to Key West take 3 hours 3 minutes. Flights to Key West from other popular cities in the United States will vary in length. Below are a few examples of popular routes and their flight times.
American Airlines weekly flight availability to Key West
The most flights to Key West operated by American Airlines are scheduled on a Saturday (11 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (10 on average).
When is the best time to book a flight to Key West with American Airlines?
The best time to book a flight to Key West with American Airlines is 29 days before departure. On average, fares are higher if you book 10 days before departure.
FAQs about flights to Key West with American Airlines
Reviews of American Airlines
See what Cheapflights users have to say about their American Airlines experience.
Overview
Reviews
American Airlines
10,000 reviews
Overview
Entertainment
6.8
Comfort
7.2
Crew
7.9
Boarding
7.5
Food
6.4
Recent reviews
10.0
|Jul 2026Awesome staff friendly and curtious
10.0
|Jul 2026Very helpful and friendly people who pushed me where I needed to go
6.0
|Jul 2026We got delayed because of filling up more gas then a storm hit after that so we sat in the plane for 1.5 hours more. It was hot while we waited.
8.0
|Jul 2026The flight was great overall. But we need better food on flights and the baggage fees are too high.
10.0
|May 2026Very modern and confortable plane. Dinner was delicious. Whole crew were polite and perfect.
1 out of 3334
Popular American Airlines flights
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Airports nearby
American Airlines
Complete your trip
Domestic flights to Key West
Flights by cabin class
Flights from EYW
Flights to EYW
Florida flights
Popular destinations
Popular flights
Popular routes
Popular United States flight routes