The best pricing can be found in the month of September. Prices to Key West from Tyler average $478. You can even find prices in September for less than $478, as users have found deals to Key West from as low as $175. The month of March appears to be one of the more expensive times to travel to Key West from Tyler. Flying in the targeted month can save you up to 66%.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Tyler to Key West as you normally would.