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Key West

$320+ Cheap flights from Panama City, FL to Key West (ECP - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
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Cheap flight deals from Panama City to Key West

Cheapest flights from Panama City to Key West
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:53 pm
ECP
-
EYW
1 stop5h 04m
Delta
Wed 9/26:15 pm
EYW
-
ECP
1 stop6h 15m
Delta
Deal found 7/26$367
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:34 pm
ECP
-
EYW
1 stop5h 28m
Delta
Thu 11/196:02 pm
EYW
-
ECP
1 stop6h 22m
Delta
Deal found 7/27$377
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:52 pm
ECP
-
EYW
1 stop5h 05m
Delta
Mon 8/246:15 pm
EYW
-
ECP
1 stop6h 15m
Delta
Deal found 7/27$397
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:34 pm
ECP
-
EYW
1 stop5h 28m
Delta
Fri 11/206:02 pm
EYW
-
ECP
1 stop6h 22m
Delta
Deal found 7/27$417
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:19 am
ECP
-
EYW
1 stop5h 47m
American Airlines
Mon 11/237:18 pm
EYW
-
ECP
1 stop5h 29m
American Airlines
Deal found 7/25$437
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:19 am
ECP
-
EYW
1 stop5h 47m
American Airlines
Mon 11/237:18 pm
EYW
-
ECP
1 stop5h 29m
American Airlines
Deal found 7/25$447
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:43 pm
ECP
-
EYW
1 stop6h 02m
American Airlines
Sun 12/138:00 am
EYW
-
ECP
1 stop7h 13m
American Airlines
Deal found 7/27$448
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:40 am
ECP
-
EYW
1 stop5h 15m
American Airlines
Sun 8/237:14 pm
EYW
-
ECP
1 stop5h 24m
American Airlines
Deal found 7/26$458
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:28 am
ECP
-
EYW
1 stop4h 39m
Delta
Tue 11/247:35 am
EYW
-
ECP
1 stop13h 33m
Delta
Deal found 7/25$462
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/211:30 pm
ECP
-
EYW
1 stop5h 13m
Delta
Fri 12/257:00 am
EYW
-
ECP
1 stop6h 39m
Delta
Deal found 7/26$468
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:34 pm
ECP
-
EYW
1 stop5h 28m
Delta
Tue 11/246:02 pm
EYW
-
ECP
1 stop15h 35m
Delta
Deal found 7/25$472
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:09 pm
ECP
-
EYW
1 stop5h 35m
American Airlines
Tue 12/294:40 pm
EYW
-
ECP
1 stop8h 13m
American Airlines
Deal found 7/26$473

Find flight deals from Panama City to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$367
(Delta)

One-way from

$320
(American Airlines)

Popular in

March

Cheapest in

November

Average price

$446
Provider with most accurate pricing for Panama City NW Florida Beaches-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Key West flights.
Search Deals
From Panama City NW Florida Beaches to Key West
Search Deals
One-way flight from Panama City NW Florida Beaches to Key West
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 8/27

1:53 pm-7:57 pm

1 stop5h 04m

Key West

Wed 9/2

6:15 pm-11:30 pm

1 stop6h 15m

$367

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 10/20

8:05 am-4:11 pm

1 stop7h 06m

Key West

Sat 10/24

7:19 pm-11:53 pm

1 stop5h 34m

$367

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 8/24

7:35 am-1:00 pm

1 stop4h 25m

Key West

Mon 8/31

6:15 pm-11:30 pm

1 stop6h 15m

$377

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sat 8/22

1:52 pm-7:57 pm

1 stop5h 05m

Key West

Mon 8/24

6:15 pm-11:30 pm

1 stop6h 15m

$397
Quickest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Wed 9/9

6:00 am-10:46 am

1 stop3h 46m

Key West

Sun 9/13

6:19 pm-9:03 pm

1 stop3h 44m

$488

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 8/11

9:27 am-5:20 pm

1 stop6h 53m

Key West

Sat 8/15

4:00 pm-9:40 pm

1 stop6h 40m

$538

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 8/13

6:00 am-10:50 am

1 stop3h 50m

Key West

Mon 8/17

11:48 am-5:56 pm

1 stop7h 08m

$558

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 8/25

6:40 am-12:55 pm

1 stop5h 15m

Key West

Thu 8/27

4:50 pm-10:40 pm

1 stop6h 50m

$565
Cheapest one-way

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 9/7

6:40 am-12:55 pm

1 stop5h 15m

$320

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 8/11

11:31 am-5:20 pm

1 stop4h 49m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Key West in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Key West

What is the cheapest month to book a flight from Panama City, Florida to Key West?

Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $317). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $671). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated July 30, 2026.
Read through reviews of airlines operating flights from Panama City to Key West, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,487 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.
Delta
7.8
Good
8,487 reviews
Delta
7.8
Good
8,487 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.8

Overall

7.8

Entertainment

7.8

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Key West?

    Airlines like Delta and American Airlines fly from Panama City, Florida to Key West in about 5h 04m. The time it takes to get you to your destination can typically vary by up to 2h 02m. Panama City, Florida and Key West are separated by a distance of 471 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Panama City, Florida to Key West round-trip?

    Delta, at $317, was found to be the cheapest airline from Panama City, Florida to Key West.. You may be able to fly from Panama City, Florida to Key West for 30% less than the average price by searching for this airline.

  • Can I find deals for flights from Panama City to Key West that include hotel bookings?

    Yes. In addition to deals on Panama City to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Key West.

  • Can I find deals for business class flights from Panama City to Key West?

    Yes. Cheapflights offers flight deals from Panama City to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Key West?

    Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $317). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $671). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Panama City to Key West

Discover the top airline that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$317Average$452FlexibilityNo cancel feeOn-timeN/A

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