$268+ Cheap flights from Panama City, FL to Key West (ECP - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Jul 18 — Jul 251
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Key West
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Best
Last-minute
One-way
Cheapest flights from Panama City to Key WestExplore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2026.
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:38 am
ECP
- EYW
1 stop4h 45m
Delta
Wed 8/51:59 pm
EYW
- ECP
1 stop5h 36m
Delta
Deal found 6/17![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Wed 7/222:24 pm
EYW
- ECP
1 stop5h 26m
Delta
Deal found 6/16![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Fri 7/247:50 am
EYW
- ECP
1 stop7h 04m
Delta
Deal found 6/17![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Thu 7/167:50 am
EYW
- ECP
1 stop5h 41m
Delta
Deal found 6/16![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
ECP
- EYW
1 stop4h 00m
Delta
Mon 7/136:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/16![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/221:30 pm
ECP
- EYW
1 stop5h 13m
Delta
Fri 12/252:35 pm
EYW
- ECP
1 stop4h 15m
Delta
Deal found 6/14![Delta logo]()
$393
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:43 am
ECP
- EYW
1 stop7h 10m
Delta
Thu 7/97:50 am
EYW
- ECP
1 stop7h 04m
Delta
Deal found 6/15![Delta logo]()
$403
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
ECP
- EYW
1 stop3h 47m
Delta
Sun 9/136:00 pm
EYW
- ECP
1 stop5h 46m
Delta
Deal found 6/16![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2811:59 am
ECP
- EYW
1 stop6h 54m
Delta
Tue 7/76:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/15![Delta logo]()
$433
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:05 am
ECP
- EYW
1 stop8h 06m
American Airlines
Fri 7/177:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 6/16![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:38 am
ECP
- EYW
1 stop4h 45m
Delta
Sun 7/127:50 am
EYW
- ECP
1 stop5h 41m
Delta
Deal found 6/16![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:00 am
ECP
- EYW
1 stop6h 49m
American Airlines
Fri 7/37:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 6/17![American Airlines logo]()
$449
Best flights from Panama City to Key WestDiscover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
Discover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 18, 2026.
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:38 am
ECP
- EYW
1 stop4h 45m
Delta
Wed 8/51:59 pm
EYW
- ECP
1 stop5h 36m
Delta
Deal found 6/17![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am
ECP
- EYW
1 stop3h 58m
Delta
Mon 12/77:00 am
EYW
- ECP
1 stop4h 15m
Delta
Deal found 6/17![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Wed 7/222:24 pm
EYW
- ECP
1 stop5h 26m
Delta
Deal found 6/16![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:47 pm
ECP
- EYW
1 stop4h 04m
Delta
Fri 7/247:50 am
EYW
- ECP
1 stop3h 58m
Delta
Deal found 6/15![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:47 pm
ECP
- EYW
1 stop5h 03m
Delta
Fri 9/256:19 pm
EYW
- ECP
1 stop5h 56m
Delta
Deal found 6/13![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Mon 7/137:50 am
EYW
- ECP
1 stop3h 58m
Delta
Deal found 6/13![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:43 am
ECP
- EYW
1 stop7h 10m
Delta
Thu 7/97:50 am
EYW
- ECP
1 stop7h 04m
Delta
Deal found 6/15![Delta logo]()
$403
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:31 pm
ECP
- EYW
1 stop5h 22m
Delta
Fri 7/106:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/15![Delta logo]()
$403
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
ECP
- EYW
1 stop3h 47m
Delta
Sun 9/136:00 pm
EYW
- ECP
1 stop5h 46m
Delta
Deal found 6/16![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am
ECP
- EYW
1 stop3h 58m
Delta
Sat 11/146:00 pm
EYW
- ECP
1 stop5h 47m
Delta
Deal found 6/16![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:38 am
ECP
- EYW
1 stop4h 45m
Delta
Fri 7/176:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/16![Delta logo]()
$448
Last-minute flights from Panama City to Key WestDiscover last-minute flight deals from Panama City to Key West. Data last updated June 18, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Key West. Data last updated June 18, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2811:59 am
ECP
- EYW
1 stop6h 54m
Delta
Wed 7/87:50 am
EYW
- ECP
1 stop3h 58m
Delta
Deal found 6/15![Delta logo]()
$433
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:43 am
ECP
- EYW
1 stop7h 10m
Delta
Thu 7/97:50 am
EYW
- ECP
1 stop7h 04m
Delta
Deal found 6/15![Delta logo]()
$403
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:00 am
ECP
- EYW
1 stop6h 49m
American Airlines
Fri 7/37:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 6/17![American Airlines logo]()
$449
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:00 am
ECP
- EYW
1 stop6h 43m
Delta
Sun 7/51:23 pm
EYW
- ECP
1 stop4h 00m
Delta
Deal found 6/15![Delta logo]()
$464
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:38 am
ECP
- EYW
1 stop4h 45m
Delta
Fri 7/176:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/16![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:05 am
ECP
- EYW
1 stop8h 06m
American Airlines
Fri 7/177:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 6/16![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/101:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Thu 7/167:50 am
EYW
- ECP
1 stop5h 41m
Delta
Deal found 6/16![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
ECP
- EYW
1 stop4h 00m
Delta
Mon 7/136:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 6/16![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1211:38 am
ECP
- EYW
1 stop4h 45m
Delta
Sat 7/187:50 am
EYW
- ECP
1 stop16h 08m
Delta
Deal found 6/16![Delta logo]()
$467
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Wed 7/222:24 pm
EYW
- ECP
1 stop5h 26m
Delta
Deal found 6/16![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:36 pm
ECP
- EYW
1 stop5h 15m
Delta
Fri 7/247:50 am
EYW
- ECP
1 stop7h 04m
Delta
Deal found 6/17![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:38 am
ECP
- EYW
1 stop4h 45m
Delta
Wed 8/51:59 pm
EYW
- ECP
1 stop5h 36m
Delta
Deal found 6/17![Delta logo]()
$347
One-way flights from Panama City to Key WestSearch for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
Search for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated June 18, 2026.
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:10 am
ECP
- EYW
1 stop8h 02m
American Airlines
Deal found 6/15![American Airlines logo]()
$268
Find flight deals from Panama City to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $347 (Delta) |
One-way from | $268 (American Airlines) |
Popular in | March |
Cheapest in | November |
Average price | $346 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 7/29
11:38 am-5:23 pm
1 stop4h 45m
Key West
Wed 8/5
1:59 pm-6:35 pm
1 stop5h 36m
$347
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Tue 12/1
6:00 am-10:58 am
1 stop3h 58m
Key West
Mon 12/7
7:00 am-10:15 am
1 stop4h 15m
$357
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Thu 7/16
1:36 pm-7:51 pm
1 stop5h 15m
Key West
Wed 7/22
2:24 pm-6:50 pm
1 stop5h 26m
$357
Quickest round-trip
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 7/17
2:47 pm-7:51 pm
1 stop4h 04m
Key West
Fri 7/24
7:50 am-10:48 am
1 stop3h 58m
$367
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Mon 9/14
1:47 pm-7:50 pm
1 stop5h 03m
Key West
Fri 9/25
6:19 pm-11:15 pm
1 stop5h 56m
$367
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 7/10
1:36 pm-7:51 pm
1 stop5h 15m
Key West
Mon 7/13
7:50 am-10:48 am
1 stop3h 58m
$377
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Mon 6/29
11:43 am-7:53 pm
1 stop7h 10m
Key West
Thu 7/9
7:50 am-1:54 pm
1 stop7h 04m
$403
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 7/1
1:31 pm-7:53 pm
1 stop5h 22m
Key West
Fri 7/10
6:18 pm-11:37 pm
1 stop6h 19m
$403
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 9/9
6:00 am-10:47 am
1 stop3h 47m
Key West
Sun 9/13
6:00 pm-10:46 pm
1 stop5h 46m
$428
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Tue 11/10
6:00 am-10:58 am
1 stop3h 58m
Key West
Sat 11/14
6:00 pm-10:47 pm
1 stop5h 47m
$428
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Panama City to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Key West in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
ECP-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Key West
What is the cheapest month to book a flight from Panama City, Florida to Key West?
Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $317). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $671). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated June 18, 2026.
Read through reviews of airlines operating flights from Panama City to Key West, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Overall
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Key West
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Complete your trip
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 18, 2026.
Panama City and Key West flights
Browse other Panama City and Key West flight options. Last updated on June 18, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on June 18, 2026.
Popular flight searches
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Top airline flying from Panama City to Key West
Discover the top airline that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$306 | Average$452 | FlexibilityNo cancel fee | On-timeN/A |