$318+ Cheap flights from Panama City, FL to Key West (ECP - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Jun 2 — Jun 91
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Key West
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Best
Last-minute
One-way
Cheapest flights from Panama City to Key WestExplore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:05 am
ECP
- EYW
1 stop8h 02m
American Airlines
Wed 6/177:29 pm
EYW
- ECP
1 stop5h 11m
American Airlines
Deal found 5/2![American Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/411:38 am
ECP
- EYW
1 stop4h 45m
Delta
Wed 8/127:00 am
EYW
- ECP
1 stop4h 13m
Delta
Deal found 4/29![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:46 am
ECP
- EYW
1 stop4h 43m
Delta
Sat 8/82:24 pm
EYW
- ECP
1 stop5h 26m
Delta
Deal found 4/29![Delta logo]()
$351
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
ECP
- EYW
1 stop4h 00m
Delta
Sun 8/96:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 4/29![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:43 pm
ECP
- EYW
1 stop4h 08m
Delta
Sat 8/86:18 pm
EYW
- ECP
1 stop5h 40m
Delta
Deal found 4/29![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:43 pm
ECP
- EYW
1 stop4h 08m
Delta
Sun 8/96:18 pm
EYW
- ECP
1 stop6h 19m
Delta
Deal found 4/29![Delta logo]()
$367
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:45 am
ECP
- EYW
1 stop7h 04m
Delta
Mon 6/17:30 am
EYW
- ECP
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:50 pm
ECP
- EYW
1 stop4h 59m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/191:22 pm
EYW
- ECP
1 stop6h 14m
Delta
Deal found 4/28![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:00 am
ECP
- EYW
1 stop6h 47m
American Airlines
Sat 7/117:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 5/1![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:50 am
ECP
- EYW
2 stops11h 08m
American Airlines
Tue 5/125:25 pm
EYW
- ECP
1 stop6h 27m
American Airlines
Deal found 4/29![American Airlines logo]()
$432
Best flights from Panama City to Key WestDiscover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:45 am
ECP
- EYW
1 stop7h 04m
Delta
Mon 6/17:30 am
EYW
- ECP
1 stop4h 21m
Delta
Deal found 5/1![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:05 am
ECP
- EYW
2 stops11h 01m
American Airlines
Sat 7/117:33 pm
EYW
- ECP
1 stop5h 04m
American Airlines
Deal found 5/1![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
ECP
- EYW
1 stop5h 27m
Delta
Tue 5/191:22 pm
EYW
- ECP
1 stop6h 14m
Delta
Deal found 4/30![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:18 pm
ECP
- EYW
2 stops9h 40m
American Airlines
Tue 5/195:25 pm
EYW
- ECP
1 stop6h 27m
American Airlines
Deal found 4/30![American Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:50 pm
ECP
- EYW
1 stop3h 59m
Delta
Sun 6/76:24 pm
EYW
- ECP
1 stop6h 20m
Delta
Deal found 4/28![Delta logo]()
$473
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:05 am
ECP
- EYW
2 stops11h 05m
American Airlines
Wed 6/171:39 pm
EYW
- ECP
2 stops11h 01m
American Airlines
Deal found 5/2![American Airlines logo]()
$531
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$477
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
ECP
- EYW
1 stop5h 27m
Delta
Sun 5/177:30 am
EYW
- ECP
1 stop6h 20m
Delta
Deal found 4/29![Delta logo]()
$523
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/911:59 am
ECP
- EYW
1 stop4h 28m
Delta
Fri 6/126:24 pm
EYW
- ECP
1 stop6h 20m
Delta
Deal found 4/28![Delta logo]()
$535
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:50 pm
ECP
- EYW
1 stop3h 59m
Delta
Sun 5/177:30 am
EYW
- ECP
1 stop6h 20m
Delta
Deal found 4/28![Delta logo]()
$583
Last-minute flights from Panama City to Key WestDiscover last-minute flight deals from Panama City to Key West. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Key West. Data last updated May 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:50 am
ECP
- EYW
2 stops11h 08m
American Airlines
Tue 5/125:25 pm
EYW
- ECP
1 stop6h 27m
American Airlines
Deal found 4/29![American Airlines logo]()
$432
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$477
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/121:50 pm
ECP
- EYW
1 stop4h 59m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:43 am
ECP
- EYW
2 stops10h 15m
American Airlines
Tue 5/195:25 pm
EYW
- ECP
1 stop6h 27m
American Airlines
Deal found 4/28![American Airlines logo]()
$482
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/191:22 pm
EYW
- ECP
1 stop6h 14m
Delta
Deal found 4/28![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:50 pm
ECP
- EYW
1 stop3h 59m
Delta
Mon 5/181:22 pm
EYW
- ECP
1 stop5h 34m
Delta
Deal found 4/28![Delta logo]()
$447
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:19 am
ECP
- EYW
1 stop7h 04m
Delta
Tue 5/196:19 pm
EYW
- ECP
1 stop5h 42m
Delta
Deal found 4/28![Delta logo]()
$453
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:40 pm
ECP
- EYW
1 stop4h 56m
American Airlines
Wed 5/206:45 am
EYW
- ECP
2 stops10h 18m
American Airlines
Deal found 5/1![American Airlines logo]()
$474
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:45 am
ECP
- EYW
1 stop7h 04m
Delta
Mon 6/17:30 am
EYW
- ECP
1 stop4h 21m
Delta
Deal found 4/29![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:05 am
ECP
- EYW
2 stops11h 05m
American Airlines
Mon 6/17:29 pm
EYW
- ECP
1 stop5h 11m
American Airlines
Deal found 4/29![American Airlines logo]()
$442
One-way flights from Panama City to Key WestSearch for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:50 pm
ECP
- EYW
1 stop3h 59m
Delta
Deal found 5/2![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:05 am
ECP
- EYW
2 stops11h 05m
American Airlines
Deal found 5/2![American Airlines logo]()
$403
Find flight deals from Panama City to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $341 (American Airlines) |
One-way from | $318 (Delta) |
Popular in | March |
Cheapest in | February |
Average price | $428 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Mon 5/25
11:45 am-7:49 pm
1 stop7h 04m
Key West
Mon 6/1
7:30 am-10:51 am
1 stop4h 21m
$377
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 7/3
7:05 am-7:06 pm
2 stops11h 01m
Key West
Sat 7/11
7:33 pm-11:37 pm
1 stop5h 04m
$429
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 5/15
6:00 am-12:27 pm
1 stop5h 27m
Key West
Tue 5/19
1:22 pm-6:36 pm
1 stop6h 14m
$437
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Fri 5/15
12:18 pm-10:58 pm
2 stops9h 40m
Key West
Tue 5/19
5:25 pm-10:52 pm
1 stop6h 27m
$442
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Sat 5/16
9:19 am-5:23 pm
1 stop7h 04m
Key West
Tue 5/19
6:19 pm-11:01 pm
1 stop5h 42m
$453
Quickest round-trip
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 6/3
2:50 pm-7:49 pm
1 stop3h 59m
Key West
Sun 6/7
6:24 pm-11:44 pm
1 stop6h 20m
$473
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Sun 5/10
9:19 am-5:23 pm
1 stop7h 04m
Key West
Tue 5/19
6:19 pm-11:01 pm
1 stop5h 42m
$477
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Thu 5/14
6:00 am-12:27 pm
1 stop5h 27m
Key West
Sun 5/17
7:30 am-12:50 pm
1 stop6h 20m
$523
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Wed 6/10
7:05 am-7:10 pm
2 stops11h 05m
Key West
Wed 6/17
1:39 pm-11:40 pm
2 stops11h 01m
$531
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Tue 6/9
11:59 am-5:27 pm
1 stop4h 28m
Key West
Fri 6/12
6:24 pm-11:44 pm
1 stop6h 20m
$535
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Key West in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
ECP-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Key West
What is the cheapest month to book a flight from Panama City, Florida to Key West?
Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Key West (average of $332). Flying from Panama City, Florida to Key West in March is currently the most expensive (average of $577). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated May 3, 2026.
Read through reviews of airlines operating flights from Panama City to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Entertainment
7.8
Overall
7.9
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for Panama City to Key West
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Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Key West by cabin class
Find flights from Panama City to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Panama City and Key West flights
Browse other Panama City and Key West flight options. Last updated on May 3, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Key West
Discover the top 2 airlines that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$332 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$452 | FlexibilityNo cancel fee | On-timeN/A |