$283+ Cheap flights from Panama City, FL to Key West (ECP - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Key West
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Cheapest flights from Panama City to Key WestExplore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Panama City to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Tue 10/207:40 am -
1 stop3h 55m
Deal found 9/12![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:36 pm -
1 stop5h 26m
Wed 12/96:06 pm -
1 stop6h 11m
Deal found 9/11![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:36 pm -
1 stop5h 26m
Fri 12/117:25 am -
1 stop6h 27m
Deal found 9/11![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:45 pm -
1 stop4h 16m
Wed 11/116:05 pm -
1 stop6h 19m
Deal found 9/10![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Mon 10/192:00 pm -
1 stop4h 35m
Deal found 9/12![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:37 pm -
1 stop5h 25m
Fri 12/117:25 am -
1 stop6h 27m
Deal found 9/11![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop3h 46m
Mon 10/511:42 am -
1 stop4h 49m
Deal found 9/12![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
1 stop7h 56m
Sun 11/17:18 pm -
1 stop5h 30m
Deal found 9/12![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Sun 10/186:10 pm -
1 stop6h 08m
Deal found 9/12![Delta logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:15 am -
1 stop7h 56m
Tue 11/33:41 pm -
1 stop8h 11m
Deal found 9/12![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:54 am -
1 stop5h 02m
Tue 11/105:50 pm -
1 stop6h 02m
Deal found 9/14![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:15 am -
1 stop7h 56m
Sun 11/17:18 pm -
1 stop5h 30m
Deal found 9/12![American Airlines logo]()
$467
Best flights from Panama City to Key WestDiscover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Panama City to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:45 pm -
1 stop4h 16m
Wed 11/116:05 pm -
1 stop6h 19m
Deal found 9/10![Delta logo]()
$417
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Mon 10/192:00 pm -
1 stop4h 35m
Deal found 9/12![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:19 am -
1 stop6h 56m
Sat 10/246:11 pm -
1 stop6h 07m
Deal found 9/13![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:35 pm -
1 stop5h 26m
Tue 10/206:10 pm -
1 stop6h 08m
Deal found 9/12![Delta logo]()
$458
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:35 pm -
1 stop5h 26m
Thu 10/226:10 pm -
1 stop3h 56m
Deal found 9/12![Delta logo]()
$468
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:35 pm -
1 stop5h 26m
Thu 10/226:10 pm -
1 stop6h 08m
Deal found 9/12![Delta logo]()
$468
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:40 pm -
2 stops27h 22m
Thu 12/1011:43 am -
1 stop4h 14m
Deal found 9/11![Delta logo]()
$511
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:04 am -
1 stop5h 07m
Fri 12/116:06 pm -
1 stop19h 43m
Deal found 9/11![Delta logo]()
$522
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:59 pm -
1 stop24h 03m
Thu 12/106:06 pm -
1 stop6h 11m
Deal found 9/11![Delta logo]()
$522
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop13h 02m
Thu 12/107:25 am -
1 stop4h 09m
Deal found 9/11![Delta logo]()
$522
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:04 am -
1 stop5h 07m
Wed 12/96:06 pm -
1 stop6h 11m
Deal found 9/11![Delta logo]()
$565
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop6h 11m
Sat 12/56:06 pm -
1 stop6h 11m
Deal found 9/11![Delta logo]()
$565
Last-minute flights from Panama City to Key WestDiscover last-minute flight deals from Panama City to Key West. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Key West. Data last updated September 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:29 am -
1 stop5h 20m
Mon 10/57:19 pm -
1 stop5h 34m
Deal found 9/14![American Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Tue 10/207:40 am -
1 stop3h 55m
Deal found 9/12![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Mon 10/192:00 pm -
1 stop4h 35m
Deal found 9/12![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:19 am -
1 stop6h 56m
Sat 10/246:11 pm -
1 stop6h 07m
Deal found 9/13![Delta logo]()
$437
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop3h 47m
Thu 11/52:00 pm -
1 stop6h 53m
Deal found 9/12![Delta logo]()
$387
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop3h 47m
Mon 11/26:11 pm -
1 stop6h 07m
Deal found 9/12![Delta logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
1 stop7h 56m
Tue 11/35:50 pm -
1 stop6h 02m
Deal found 9/12![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:15 am -
1 stop7h 56m
Sun 11/17:18 pm -
1 stop5h 30m
Deal found 9/12![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
1 stop3h 47m
Thu 11/52:00 pm -
1 stop6h 53m
Deal found 9/12![Delta logo]()
$397
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:15 am -
1 stop7h 56m
Tue 11/33:41 pm -
1 stop8h 11m
Deal found 9/12![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:15 am -
1 stop7h 56m
Sun 11/17:18 pm -
1 stop5h 30m
Deal found 9/12![American Airlines logo]()
$467
One-way flights from Panama City to Key WestSearch for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Panama City to Key West. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:45 pm -
1 stop4h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:05 pm -
2 stops17h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:35 am -
1 stop4h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Delta logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:50 pm -
3 stops23h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:29 am -
2 stops9h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:17 pm -
2 stops18h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$772
Find flight deals from Panama City to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $377 (Delta) |
One-way from | $283 (Delta) |
Popular in | September |
Cheapest in | February |
Average price | $678 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Panama City to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Sat 11/7
2:45 pm-8:01 pm
1 stop4h 16m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$283
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Wed 9/23
7:35 am-12:53 pm
1 stop4h 18m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$413
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Tue 9/22
7:35 am-12:53 pm
1 stop4h 18m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$413
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Sat 11/7
1:50 pm-1:56 pm
3 stops23h 06m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$416
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Sat 11/7
2:45 pm-8:01 pm
1 stop4h 16m
Key West
Wed 11/11
6:05 pm-11:24 pm
1 stop6h 19m
$417
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Tue 10/13
6:00 am-10:47 am
1 stop3h 47m
Key West
Mon 10/19
2:00 pm-5:35 pm
1 stop4h 35m
$427
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Mon 10/19
9:19 am-5:15 pm
1 stop6h 56m
Key West
Sat 10/24
6:11 pm-11:18 pm
1 stop6h 07m
$437
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Tue 9/22
8:29 am-7:17 pm
2 stops9h 48m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$458
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Wed 10/14
1:35 pm-8:01 pm
1 stop5h 26m
Key West
Tue 10/20
6:10 pm-11:18 pm
1 stop6h 08m
$458
Panama CityKey West
ECP Panama City NW Florida Beaches - EYW Key West
ECPEYW
Panama City NW Florida Beaches
Thu 10/15
1:35 pm-8:01 pm
1 stop5h 26m
Key West
Thu 10/22
6:10 pm-9:06 pm
1 stop3h 56m
$468
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Panama City to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Key West in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Panama City with our price prediction graph.
ECP-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 14, 2026.
Read through reviews of airlines operating flights from Panama City to Key West, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Panama City to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Key West by cabin class
Find flights from Panama City to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Panama City and Key West flights
Browse other Panama City and Key West flight options. Last updated on September 14, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Key West
Discover the top airline that operate flights from Panama City to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$336 | Average$452 | FlexibilityNo cancel fee | On-timeN/A |