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Panama City

$268+ Cheap flights from Key West to Panama City, FL (EYW - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — ECP
Aug 17 — Aug 241
Mon 8/17
Mon 8/24
1 adult, Economy
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Cheap flight deals from Key West to Panama City

Cheapest flights from Key West to Panama City
Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.

This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:50 pm
EYW
-
ECP
1 stop6h 50m
American Airlines
Sun 8/307:10 am
ECP
-
EYW
1 stop8h 01m
American Airlines
Deal found 7/14$367
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:33 pm
EYW
-
ECP
1 stop5h 04m
American Airlines
Mon 7/2011:00 am
ECP
-
EYW
1 stop6h 48m
American Airlines
Deal found 7/14$519
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:01 pm
EYW
-
ECP
1 stop6h 21m
American Airlines
Tue 7/2811:00 am
ECP
-
EYW
1 stop6h 48m
American Airlines
Deal found 7/15$549
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:33 pm
EYW
-
ECP
1 stop5h 04m
American Airlines
Wed 7/2211:00 am
ECP
-
EYW
1 stop6h 48m
American Airlines
Deal found 7/15$569
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:33 pm
EYW
-
ECP
1 stop5h 04m
American Airlines
Sat 7/2511:00 am
ECP
-
EYW
1 stop5h 21m
American Airlines
Deal found 7/15$589
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:50 am
EYW
-
ECP
1 stop7h 04m
Delta
Tue 7/282:47 pm
ECP
-
EYW
1 stop4h 04m
Delta
Deal found 7/15$592
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:01 pm
EYW
-
ECP
1 stop6h 21m
American Airlines
Sat 7/257:05 am
ECP
-
EYW
2 stops11h 18m
American Airlines
Deal found 7/15$596
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:33 pm
EYW
-
ECP
1 stop5h 04m
American Airlines
Fri 7/2411:00 am
ECP
-
EYW
1 stop6h 48m
American Airlines
Deal found 7/15$620
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:28 am
EYW
-
ECP
2 stops7h 54m
American Airlines
Sat 7/257:05 am
ECP
-
EYW
2 stops11h 18m
American Airlines
Deal found 7/15$644
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:28 am
EYW
-
ECP
2 stops7h 54m
American Airlines
Sun 7/267:05 am
ECP
-
EYW
1 stop8h 06m
American Airlines
Deal found 7/15$681

Find flight deals from Key West to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$367
(American Airlines)

One-way from

$268
(Delta)
Provider with most accurate pricing for Key West-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Panama City NW Florida Beaches flights.
Search Deals
From Key West to Panama City NW Florida Beaches
Search Deals
One-way flight from Key West to Panama City NW Florida Beaches
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Key West to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 8/27

4:50 pm-10:40 pm

1 stop6h 50m

Panama City NW Florida Beaches

Sun 8/30

7:10 am-4:11 pm

1 stop8h 01m

$367

Key WestPanama City

EYW - ECP

EYWECP

Key West

Sat 8/1

5:19 pm-12:04 pm

1 stop19h 45m

Panama City NW Florida Beaches

Wed 8/5

6:40 am-12:55 pm

1 stop5h 15m

$907
Cheapest one-way

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 10/23

7:40 am-12:50 pm

1 stop6h 10m

$268
Quickest one-way

Key WestPanama City

EYW - ECP

EYWECP

Key West

Sat 10/24

7:19 pm-11:53 pm

1 stop5h 34m

$268

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 8/14

6:15 pm-11:30 pm

1 stop6h 15m

$268

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 8/13

1:59 pm-8:08 pm

1 stop7h 09m

$288

Key WestPanama City

EYW - ECP

EYWECP

Key West

Thu 8/13

4:50 pm-10:40 pm

1 stop6h 50m

$318

Key WestPanama City

EYW - ECP

EYWECP

Key West

Fri 8/14

1:41 pm-10:40 pm

2 stops9h 59m

$425

Key WestPanama City

EYW - ECP

EYWECP

Key West

Mon 10/26

5:28 pm-11:53 pm

2 stops7h 25m

$425

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/17

Sorted by cheapest first

Compare providers for flights from Key West to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Panama City in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Key West to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Panama City, Florida?

    American Airlines can get you from Key West to Panama City, Florida in just under 6h 50m. Your travel time can differ by up to . The distance between Key West and Panama City, Florida is about 471 mi.

  • Can I find deals for flights from Key West to Panama City that include hotel bookings?

    Yes. In addition to deals on Key West to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Panama City.

  • Can I find deals for business class flights from Key West to Panama City?

    Yes. Cheapflights offers flight deals from Key West to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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