$590+ Cheap flights from Key West to Panama City, FL (EYW - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — ECP
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Key West to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Key West to Panama City
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Best
Last-minute
One-way
Cheapest flights from Key West to Panama CityExplore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Key West to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:08 pm -
1 stop6h 16m
Thu 12/31:38 pm -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$653
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:57 pm -
2 stops6h 55m
Wed 11/1812:00 pm -
1 stop5h 01m
Deal found 10/29![American Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:18 pm -
1 stop5h 29m
Thu 12/37:10 am -
2 stops11h 20m
Deal found 10/29![American Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:30 am -
1 stop6h 12m
Wed 11/186:00 am -
1 stop3h 48m
Deal found 10/29![Delta logo]()
$743
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:10 pm -
2 stops19h 42m
Thu 12/31:58 pm -
3 stops23h 38m
Deal found 10/29![United Airlines logo]()
$1,217
Best flights from Key West to Panama CityDiscover carefully curated flight deals from Key West to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Key West to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:18 pm -
1 stop5h 29m
Thu 12/37:10 am -
2 stops11h 20m
Deal found 10/29![American Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:30 am -
1 stop6h 12m
Wed 11/186:00 am -
1 stop3h 48m
Deal found 10/29![Delta logo]()
$743
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:15 pm -
2 stops23h 12m
Wed 2/32:56 pm -
2 stops22h 17m
Deal found 10/29![United Airlines logo]()
$1,187
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:57 pm -
2 stops6h 55m
Wed 11/188:19 am -
2 stops7h 56m
Deal found 10/29![American Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:10 pm -
2 stops19h 42m
Thu 12/31:58 pm -
3 stops23h 38m
Deal found 10/29![United Airlines logo]()
$1,217
Last-minute flights from Key West to Panama CityDiscover last-minute flight deals from Key West to Panama City. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Key West to Panama City. Data last updated October 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:57 pm -
2 stops6h 55m
Wed 11/1812:00 pm -
1 stop5h 01m
Deal found 10/29![American Airlines logo]()
$665
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:30 am -
1 stop6h 12m
Wed 11/186:00 am -
1 stop3h 48m
Deal found 10/29![Delta logo]()
$743
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:08 pm -
1 stop6h 16m
Thu 12/31:38 pm -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$653
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:18 pm -
1 stop5h 29m
Thu 12/37:10 am -
2 stops11h 20m
Deal found 10/29![American Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:10 pm -
2 stops19h 42m
Thu 12/31:58 pm -
3 stops23h 38m
Deal found 10/29![United Airlines logo]()
$1,217
One-way flights from Key West to Panama CitySearch for one-way flight options from Key West to Panama City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Key West to Panama City. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:08 pm -
1 stop6h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$590
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 pm -
2 stops17h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$832
Find flight deals from Key West to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $653 (Delta) |
One-way from | $590 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Key West to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Key West to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Sun 11/15
6:08 pm-11:24 pm
1 stop6h 16m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$590
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Thu 11/19
7:18 pm-11:47 pm
1 stop5h 29m
Panama City NW Florida Beaches
Thu 12/3
7:10 am-7:30 pm
2 stops11h 20m
$691
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Sat 11/14
4:57 pm-10:52 pm
2 stops6h 55m
Panama City NW Florida Beaches
Wed 11/18
8:19 am-5:15 pm
2 stops7h 56m
$719
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Sat 11/14
7:30 am-12:42 pm
1 stop6h 12m
Panama City NW Florida Beaches
Wed 11/18
6:00 am-10:48 am
1 stop3h 48m
$743
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Sun 11/15
7:00 pm-11:30 am
2 stops17h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$832
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Sat 1/30
3:15 pm-1:27 pm
2 stops23h 12m
Panama City NW Florida Beaches
Wed 2/3
2:56 pm-2:13 pm
2 stops22h 17m
$1,187
Key WestPanama City
EYW Key West - ECP Panama City NW Florida Beaches
EYWECP
Key West
Thu 11/19
4:10 pm-10:52 am
2 stops19h 42m
Panama City NW Florida Beaches
Thu 12/3
1:58 pm-2:36 pm
3 stops23h 38m
$1,217
Sorted by cheapest first
Compare providers for flights from Key West to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Key West-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Key West-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Key West to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Key West with our price prediction graph.
EYW-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Key West to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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