$178+ Cheap flights from LaGuardia, NY (LGA) to Panama City, FL (ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — ECP
Dec 4 — Dec 111
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from LaGuardia to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from New York LaGuardia to Panama City NW Florida Beaches are usually found in January or July, booked 89 days in advance, depart on a Tuesday or Monday and return on a Wednesday
Cheap flight deals from LaGuardia to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from LaGuardia to Panama CityExplore the most affordable flight options available from LaGuardia to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from LaGuardia to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:00 pm -
1 stop7h 15m
Sun 12/63:00 pm -
1 stop6h 55m
Deal found 11/1![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
Nonstop3h 13m
Sun 12/612:57 pm -
Nonstop2h 33m
Deal found 11/2![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:45 am -
Nonstop3h 13m
Sat 12/125:16 pm -
1 stop5h 24m
Deal found 11/2![Delta logo]()
$390
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:05 pm -
1 stop7h 30m
Mon 12/74:10 pm -
1 stop5h 30m
Deal found 10/31![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:30 am -
1 stop6h 40m
Mon 12/71:40 pm -
1 stop5h 50m
Deal found 11/3![American Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:05 pm -
1 stop7h 30m
Tue 12/84:10 pm -
1 stop5h 30m
Deal found 11/2![Southwest logo]()
$426
Best flights from LaGuardia to Panama CityDiscover carefully curated flight deals from LaGuardia to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from LaGuardia to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:00 am -
1 stop6h 01m
Sun 12/612:57 pm -
Nonstop2h 33m
Deal found 11/1![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/224:30 pm -
1 stop5h 50m
Tue 4/276:15 am -
1 stop8h 15m
Deal found 11/3![Southwest logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops11h 13m
Mon 12/141:30 pm -
1 stop7h 07m
Deal found 10/30![United Airlines logo]()
$530
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2310:30 am -
Nonstop3h 01m
Sat 3/279:23 am -
1 stop6h 17m
Deal found 11/3![Delta logo]()
$389
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/233:00 pm -
1 stop5h 36m
Fri 4/304:10 pm -
1 stop6h 31m
Deal found 11/2![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:35 am -
2 stops11h 05m
Mon 1/181:05 pm -
2 stops8h 55m
Deal found 11/2![Southwest logo]()
$544
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2410:00 am -
2 stops11h 06m
Sat 5/16:30 am -
1 stop9h 10m
Deal found 10/30![United Airlines logo]()
$613
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:48 am -
Nonstop3h 05m
Wed 11/256:00 am -
1 stop4h 43m
Deal found 10/31![Delta logo]()
$529
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:15 am -
2 stops12h 55m
Wed 11/256:15 am -
2 stops8h 40m
Deal found 10/31![Southwest logo]()
$614
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
1 stop9h 40m
Sat 12/263:25 pm -
1 stop5h 05m
Deal found 10/30![Southwest logo]()
$637
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/221:00 pm -
1 stop7h 36m
Tue 4/271:14 pm -
Nonstop2h 40m
Deal found 11/3![Delta logo]()
$597
Last-minute flights from LaGuardia to Panama CityDiscover last-minute flight deals from LaGuardia to Panama City. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Panama City. Data last updated November 4, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:05 pm -
1 stop7h 30m
Tue 12/84:10 pm -
1 stop5h 30m
Deal found 11/2![Southwest logo]()
$426
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:00 pm -
1 stop7h 15m
Sun 12/63:00 pm -
1 stop6h 55m
Deal found 11/1![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
Nonstop3h 13m
Sun 12/612:57 pm -
Nonstop2h 33m
Deal found 11/2![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:05 pm -
1 stop7h 30m
Mon 12/74:10 pm -
1 stop5h 30m
Deal found 10/31![Southwest logo]()
$391
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:30 am -
1 stop6h 40m
Mon 12/71:40 pm -
1 stop5h 50m
Deal found 11/3![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:45 am -
Nonstop3h 13m
Sat 12/125:16 pm -
1 stop5h 24m
Deal found 11/2![Delta logo]()
$390
One-way flights from LaGuardia to Panama CitySearch for one-way flight options from LaGuardia to Panama City. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from LaGuardia to Panama City. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:05 pm -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$178
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/257:00 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Southwest logo]()
$183
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:08 am -
1 stop5h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:00 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$205
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:00 am -
1 stop8h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1810:25 am -
1 stop8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Southwest logo]()
$230
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:45 am -
Nonstop3h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Delta logo]()
$239
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/118:29 am -
1 stop5h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:25 am -
1 stop6h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$250
Find flight deals from LaGuardia to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $375 (Southwest) |
One-way from | $178 (Southwest) |
Popular in | March |
Cheapest in | January |
Average price | $639 |
Good round-trip deal | $448 or less |
Good one-way deal | $388 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Mon 1/25
8:00 am-3:15 pm
1 stop8h 15m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$178
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Thu 12/3
2:05 pm-8:35 pm
1 stop7h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$178
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Thu 12/3
9:45 am-11:58 am
Nonstop3h 13m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$239
Quickest round-trip
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Fri 11/27
9:48 am-11:53 am
Nonstop3h 05m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$264
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Sat 11/14
6:35 am-12:55 pm
1 stop7h 20m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$279
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Sat 11/14
9:48 am-11:53 am
Nonstop3h 05m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$299
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Thu 12/3
6:00 am-9:38 pm
3 stops16h 38m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$309
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Sat 11/28
9:48 am-11:53 am
Nonstop3h 05m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$344
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Sat 11/21
6:00 am-2:28 pm
1 stop9h 28m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$359
New YorkPanama City
LGA New York LaGuardia - ECP Panama City NW Florida Beaches
LGAECP
New York LaGuardia
Thu 1/28
6:00 am-9:40 pm
3 stops16h 40m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from LaGuardia to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from LaGuardia to Panama City in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on New York LaGuardia Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on New York LaGuardia Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from New York LaGuardia Airport-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on New York LaGuardia Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New York LaGuardia Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from LaGuardia to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from LaGuardia with our price prediction graph.
LGA-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from New York LaGuardia Airport to Panama City
Prices
Airlines
How far ahead should I book a flight from New York LaGuardia Airport to Panama City, Florida?
To ensure you get the cheapest price possible for a flight from New York LaGuardia Airport to Panama City, Florida, you should look to book at least 87 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from New York LaGuardia Airport to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from New York LaGuardia Airport to Panama City, Florida (average of $319). Flying from New York LaGuardia Airport to Panama City, Florida in March is currently the most expensive (average of $724). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LGA to ECP?
Find hourly flight availability from LaGuardia to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
When flying from New York LaGuardia Airport to Panama City, Florida, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated November 4, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from New York LaGuardia Airport to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from LaGuardia
Panama City flight routes
Popular flights
Alternative routes for LaGuardia to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from LaGuardia to Panama City by cabin class
Find flights from LaGuardia to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
LaGuardia and Panama City flights
Browse other LaGuardia and Panama City flight options. Last updated on November 4, 2026.
Other flights from LaGuardia
Browse through other flights departing from LaGuardia. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from LaGuardia to Panama City
Discover the top 3 airlines that operate flights from LaGuardia to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$489 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$280 | Average$433 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$319 | Average$388 | FlexibilityNo cancel fee | On-time71% |