$149+ Cheap flights from San Diego to Key West (SAN - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
Aug 10 — Aug 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Key West
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Best
Last-minute
One-way
Cheapest flights from San Diego to Key WestExplore the most affordable flight options available from San Diego to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
Explore the most affordable flight options available from San Diego to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:30 pm
SAN
- EYW
1 stop10h 20m
Delta
Mon 8/176:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/10![Delta logo]()
$411
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:25 pm
SAN
- EYW
1 stop9h 25m
Delta
Sun 8/307:40 am
EYW
- SAN
1 stop7h 53m
Delta
Deal found 7/10![Delta logo]()
$456
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Wed 8/261:50 pm
EYW
- SAN
1 stop8h 54m
American Airlines
Deal found 7/10![American Airlines logo]()
$460
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:15 am
SAN
- EYW
1 stop8h 08m
Delta
Mon 8/36:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/9![Delta logo]()
$490
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:57 pm
SAN
- EYW
2 stops12h 51m
Delta
Sat 10/317:40 am
EYW
- SAN
1 stop8h 00m
Delta
Deal found 7/8![Delta logo]()
$537
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:45 pm
SAN
- EYW
1 stop9h 23m
American Airlines
Tue 8/181:40 pm
EYW
- SAN
2 stops9h 14m
American Airlines
Deal found 7/9![American Airlines logo]()
$542
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2612:09 pm
SAN
- EYW
1 stop19h 18m
Multiple Airlines
Thu 7/309:22 pm
EYW
- SAN
2 stops21h 05m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$564
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Sun 8/302:30 pm
EYW
- SAN
1 stop9h 41m
American Airlines
Deal found 7/9![American Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:45 pm
SAN
- EYW
1 stop7h 59m
American Airlines
Mon 8/171:50 pm
EYW
- SAN
2 stops10h 13m
American Airlines
Deal found 7/10![American Airlines logo]()
$618
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:28 pm
SAN
- EYW
1 stop10h 46m
American Airlines
Mon 8/311:28 am
EYW
- SAN
2 stops11h 35m
American Airlines
Deal found 7/9![American Airlines logo]()
$663
Best flights from San Diego to Key WestDiscover carefully curated flight deals from San Diego to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
Discover carefully curated flight deals from San Diego to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 am
SAN
- EYW
1 stop6h 39m
American Airlines
Sat 10/312:35 pm
EYW
- SAN
1 stop8h 29m
American Airlines
Deal found 7/8![American Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:30 pm
SAN
- EYW
1 stop10h 20m
Delta
Mon 8/176:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/10![Delta logo]()
$411
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:25 pm
SAN
- EYW
1 stop9h 25m
Delta
Tue 8/186:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/11![Delta logo]()
$411
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Wed 8/261:50 pm
EYW
- SAN
1 stop8h 54m
American Airlines
Deal found 7/11![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:15 am
SAN
- EYW
1 stop7h 15m
American Airlines
Wed 1/62:43 pm
EYW
- SAN
1 stop7h 29m
American Airlines
Deal found 7/11![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:15 am
SAN
- EYW
1 stop8h 08m
Delta
Mon 8/36:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/9![Delta logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:45 pm
SAN
- EYW
1 stop9h 23m
American Airlines
Tue 8/181:40 pm
EYW
- SAN
2 stops9h 14m
American Airlines
Deal found 7/8![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Sun 8/302:30 pm
EYW
- SAN
1 stop9h 41m
American Airlines
Deal found 7/10![American Airlines logo]()
$603
Last-minute flights from San Diego to Key WestDiscover last-minute flight deals from San Diego to Key West. Data last updated July 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Key West. Data last updated July 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/2612:09 pm
SAN
- EYW
1 stop19h 18m
Multiple Airlines
Thu 7/309:22 pm
EYW
- SAN
2 stops21h 05m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:15 am
SAN
- EYW
1 stop8h 08m
Delta
Mon 8/36:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/9![Delta logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:28 pm
SAN
- EYW
1 stop10h 46m
American Airlines
Mon 8/311:28 am
EYW
- SAN
2 stops11h 35m
American Airlines
Deal found 7/9![American Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:30 pm
SAN
- EYW
1 stop10h 20m
Delta
Mon 8/176:15 pm
EYW
- SAN
1 stop7h 45m
Delta
Deal found 7/7![Delta logo]()
$411
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:45 pm
SAN
- EYW
1 stop9h 23m
American Airlines
Tue 8/181:40 pm
EYW
- SAN
2 stops9h 14m
American Airlines
Deal found 7/9![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:45 pm
SAN
- EYW
1 stop7h 59m
American Airlines
Mon 8/171:50 pm
EYW
- SAN
2 stops10h 13m
American Airlines
Deal found 7/10![American Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:25 pm
SAN
- EYW
1 stop9h 25m
Delta
Sun 8/307:40 am
EYW
- SAN
1 stop7h 53m
Delta
Deal found 7/10![Delta logo]()
$456
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Wed 8/261:50 pm
EYW
- SAN
1 stop8h 54m
American Airlines
Deal found 7/10![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:22 pm
SAN
- EYW
2 stops14h 22m
American Airlines
Sun 8/302:30 pm
EYW
- SAN
1 stop9h 41m
American Airlines
Deal found 7/9![American Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:20 pm
SAN
- EYW
2 stops11h 45m
American Airlines
Tue 9/11:50 pm
EYW
- SAN
2 stops10h 13m
American Airlines
Deal found 7/11![American Airlines logo]()
$673
One-way flights from San Diego to Key WestSearch for one-way flight options from San Diego to Key West. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
Search for one-way flight options from San Diego to Key West. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:45 pm
SAN
- EYW
2 stops17h 49m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:45 pm
SAN
- EYW
2 stops17h 49m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:25 am
SAN
- EYW
2 stops27h 22m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$219
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:20 pm
SAN
- EYW
1 stop12h 09m
United Airlines
Deal found 7/9![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:15 am
SAN
- EYW
1 stop7h 14m
American Airlines
Deal found 7/7![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:15 am
SAN
- EYW
1 stop8h 01m
Delta
Deal found 7/8![Delta logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2410:24 am
SAN
- EYW
3 stops20h 55m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$543
Find flight deals from San Diego to Key West
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $411 (American Airlines) |
One-way from | $149 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $548 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from San Diego to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Tue 10/27
7:15 am-4:54 pm
1 stop6h 39m
Key West
Sat 10/31
2:35 pm-8:04 pm
1 stop8h 29m
$411
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Fri 8/14
9:30 pm-10:50 am
1 stop10h 20m
Key West
Mon 8/17
6:15 pm-11:00 pm
1 stop7h 45m
$411
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Fri 8/14
10:25 pm-10:50 am
1 stop9h 25m
Key West
Tue 8/18
6:15 pm-11:00 pm
1 stop7h 45m
$411
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Sat 8/22
4:22 pm-9:44 am
2 stops14h 22m
Key West
Wed 8/26
1:50 pm-7:44 pm
1 stop8h 54m
$460
Quickest round-trip
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Fri 1/1
6:15 am-4:30 pm
1 stop7h 15m
Key West
Wed 1/6
2:43 pm-7:12 pm
1 stop7h 29m
$473
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Mon 7/27
6:15 am-5:23 pm
1 stop8h 08m
Key West
Mon 8/3
6:15 pm-11:00 pm
1 stop7h 45m
$490
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Fri 8/14
10:45 pm-11:08 am
1 stop9h 23m
Key West
Tue 8/18
1:40 pm-7:54 pm
2 stops9h 14m
$542
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Sat 8/22
4:22 pm-9:44 am
2 stops14h 22m
Key West
Sun 8/30
2:30 pm-9:11 pm
1 stop9h 41m
$603
Cheapest one-way
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Wed 10/7
6:25 am-7:55 pm
3 stops34h 30m
$231
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Mon 8/31
10:20 pm-1:29 pm
1 stop12h 09m
$374
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from San Diego to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Key West in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from San Diego with our price prediction graph.
SAN-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated July 11, 2026.
Read reviews from past customers who have flown American Airlines from San Diego to Key West. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Entertainment
6.8
Boarding
7.5
Overall
7.1
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Crew
7.9
Food
6.4
Entertainment
6.8
Boarding
7.5
Overall
7.1
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from San Diego to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Diego to Key West
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Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Key West by cabin class
Find flights from San Diego to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 11, 2026.
San Diego and Key West flights
Browse other San Diego and Key West flight options. Last updated on July 11, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on July 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from San Diego to Key West
Discover the top airline that operate flights from San Diego to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$314 | Average$439 | FlexibilityNo cancel fee | On-time71% |