$453+ Cheap flights from Santa Ana, CA to Key West (SNA - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Key West
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Cheapest flights from Santa Ana to Key WestExplore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Santa Ana to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop8h 34m
Fri 10/302:34 pm -
1 stop8h 42m
Deal found 9/8![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:15 am -
1 stop7h 46m
Thu 12/172:30 pm -
1 stop8h 51m
Deal found 9/8![American Airlines logo]()
$566
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:02 pm -
2 stops13h 45m
Fri 10/302:00 pm -
1 stop7h 38m
Deal found 9/8![Delta logo]()
$570
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:45 am -
1 stop10h 15m
Wed 9/302:00 pm -
1 stop7h 29m
Deal found 9/11![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:45 am -
1 stop8h 02m
Tue 11/242:32 pm -
1 stop7h 43m
Deal found 9/7![American Airlines logo]()
$650
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:58 pm -
2 stops14h 48m
Tue 9/297:40 am -
1 stop7h 53m
Deal found 9/10![Delta logo]()
$757
Best flights from Santa Ana to Key WestDiscover carefully curated flight deals from Santa Ana to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Santa Ana to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/56:45 am -
1 stop7h 09m
Thu 3/112:25 pm -
1 stop8h 58m
Deal found 9/7![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:45 am -
1 stop10h 15m
Wed 9/302:00 pm -
1 stop7h 29m
Deal found 9/11![Delta logo]()
$575
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/302:38 pm -
2 stops20h 30m
Wed 2/33:55 pm -
1 stop9h 35m
Deal found 9/8![United Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop8h 34m
Fri 10/302:34 pm -
1 stop8h 42m
Deal found 9/8![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:58 pm -
2 stops14h 48m
Tue 9/297:40 am -
1 stop7h 53m
Deal found 9/10![Delta logo]()
$757
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:45 am -
1 stop8h 02m
Tue 11/244:43 pm -
2 stops8h 56m
Deal found 9/7![American Airlines logo]()
$723
Last-minute flights from Santa Ana to Key WestDiscover last-minute flight deals from Santa Ana to Key West. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Key West. Data last updated September 12, 2026 and is based on user searches.
This Gotogate deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:30 am -
3 stops23h 49m
Sun 9/2712:01 pm -
3 stops31h 14m
Deal found 9/8![Breeze Airways logo]()
$1,120
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:58 pm -
2 stops14h 48m
Tue 9/297:40 am -
1 stop7h 53m
Deal found 9/10![Delta logo]()
$757
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:45 am -
1 stop8h 10m
Tue 9/292:15 pm -
1 stop8h 52m
Deal found 9/10![American Airlines logo]()
$1,125
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:45 am -
1 stop10h 15m
Wed 9/302:00 pm -
1 stop7h 29m
Deal found 9/11![Delta logo]()
$575
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:15 am -
1 stop8h 34m
Mon 10/192:34 pm -
1 stop8h 42m
Deal found 9/11![American Airlines logo]()
$845
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:15 am -
1 stop8h 34m
Fri 10/302:34 pm -
1 stop8h 42m
Deal found 9/8![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:02 pm -
2 stops13h 45m
Fri 10/302:00 pm -
1 stop7h 38m
Deal found 9/8![Delta logo]()
$570
One-way flights from Santa Ana to Key WestSearch for one-way flight options from Santa Ana to Key West. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Santa Ana to Key West. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 am -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:45 am -
1 stop7h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$466
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:45 am -
1 stop7h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Delta logo]()
$530
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:30 am -
3 stops22h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Breeze Airways logo]()
$585
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 am -
2 stops9h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$597
This KAYAK deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:30 am -
3 stops22h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Breeze Airways logo]()
$640
This KAYAK deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:30 am -
3 stops23h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Breeze Airways logo]()
$671
This KAYAK deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:30 am -
3 stops22h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Breeze Airways logo]()
$770
Find flight deals from Santa Ana to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $545 (American Airlines) |
One-way from | $453 (American Airlines) |
Popular in | March |
Cheapest in | November |
Average price | $437 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Santa Ana to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Fri 11/20
6:45 am-4:54 pm
1 stop7h 09m
Key West
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$453
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Tue 9/22
6:45 am-5:23 pm
1 stop7h 38m
Key West
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$466
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Fri 9/18
6:45 am-5:23 pm
1 stop7h 38m
Key West
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$530
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Fri 3/5
6:45 am-4:54 pm
1 stop7h 09m
Key West
Thu 3/11
2:25 pm-8:23 pm
1 stop8h 58m
$545
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Fri 10/23
7:15 am-6:49 pm
1 stop8h 34m
Key West
Fri 10/30
2:34 pm-8:16 pm
1 stop8h 42m
$545
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Sat 9/26
6:45 am-8:00 pm
1 stop10h 15m
Key West
Wed 9/30
2:00 pm-6:29 pm
1 stop7h 29m
$575
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Tue 9/22
7:30 am-9:24 am
3 stops22h 54m
Key West
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$585
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Sat 11/21
6:45 am-7:07 pm
2 stops9h 22m
Key West
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$597
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Sat 1/30
2:38 pm-2:08 pm
2 stops20h 30m
Key West
Wed 2/3
3:55 pm-10:30 pm
1 stop9h 35m
$612
Santa AnaKey West
SNA Santa Ana J. Wayne/Orange Cnty - EYW Key West
SNAEYW
Santa Ana J. Wayne/Orange Cnty
Thu 11/19
7:45 am-6:47 pm
1 stop8h 02m
Key West
Tue 11/24
4:43 pm-10:39 pm
2 stops8h 56m
$723
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Key West in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Santa Ana with our price prediction graph.
SNA-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 12, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Santa Ana to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Santa Ana and Key West flights
Browse other Santa Ana and Key West flight options. Last updated on September 12, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Santa Ana to Key West
Discover the top 2 airlines that operate flights from Santa Ana to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$348 | Average$666 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$443 | Average$723 | FlexibilityNo cancel fee | On-timeN/A |