HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Key West

$249+ Cheap flights from Myrtle Beach to Key West (MYR - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
Jul 12 — Jul 191
Sat 7/12
Sat 7/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Key West with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Myrtle Beach Intl to Key West are usually found in June or August, booked 13 days in advance, depart on a Wednesday or Friday and return on a Wednesday

Cheap flight deals from Myrtle Beach to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 7, 2025.

Round-trip from

$249
(Delta)

Popular in

March

Cheapest in

June

Average price

$438
From Myrtle Beach Intl to Key West
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Myrtle Beach to Key West

Cheapest flights from Myrtle Beach to Key West
Explore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2025.

This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/164:00 pmMYR - EYW
1 stop4h 12mDelta
Wed 8/206:22 pmEYW - MYR
1 stop5h 27mDelta
Deal found 7/5$249
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2110:17 amMYR - EYW
1 stop5h 50mAmerican Airlines
Tue 10/2811:22 amEYW - MYR
2 stops7h 22mAmerican Airlines
Deal found 7/6$254
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/216:10 amMYR - EYW
1 stop6h 57mMultiple Airlines
Fri 7/2510:23 amEYW - MYR
1 stop6h 39mMultiple Airlines
Deal found 7/6$333

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.

Fly from

Myrtle Beach

Fly to

Key West

Route

Depart

Return

Price

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 8/16

4:00 pm-8:12 pm

1 stop4h 12m

Key West

Tue 8/19

7:00 am-1:35 pm

1 stop6h 35m

$249

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 10/21

10:17 am-4:07 pm

1 stop5h 50m

Key West

Tue 10/28

11:22 am-6:44 pm

2 stops7h 22m

$254

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Mon 7/21

6:10 am-1:07 pm

1 stop6h 57m

Key West

Fri 7/25

10:23 am-5:02 pm

1 stop6h 39m

$333

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Sat 8/2

2:47 pm-12:41 pm

3 stops21h 54m

Key West

Thu 8/7

2:22 pm-2:06 pm

2 stops23h 44m

$602

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/5

Best time to book a flight from Myrtle Beach to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Key West

How far ahead should I book a flight from Myrtle Beach to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Key West. Price data was last updated on June 27, 2025.

The best time to book flights from Myrtle Beach to Key West is 12 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Myrtle Beach to Key West?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $328). Flying from Myrtle Beach to Key West in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to EYW?

Find hourly flight availability from Myrtle Beach to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 7, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Key West is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 9% on airfare.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated July 7, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Myrtle Beach to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
Delta
8.0
Very good
7,962 reviews
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
United Airlines
7.4
Good
8,844 reviews
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,962 reviews

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Lucy,Nov 2023

CAE - ATL

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to Key West round-trip?

    According to our current data, Delta ($249), American Airlines ($254), and United Airlines ($602) offers the cheapest pricing from Myrtle Beach to Key West. Users have found that Delta is 44% cheaper than the other options available to this destination.

  • Can I find deals for flights from Myrtle Beach to Key West that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Key West.

  • Can I find deals for business class flights from Myrtle Beach to Key West?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Key West?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $328). Flying from Myrtle Beach to Key West in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Key West

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charlotte to Orlando flights
Charleston to Fort Lauderdale flights
Charlotte to Tampa flights
Charleston to Miami flights
Charlotte to West Palm Beach flights
Charlotte to Key West flights
Greenville to Miami flights
Savannah to Miami flights
Myrtle Beach to Fort Lauderdale flights
Columbia to Miami flights
Myrtle Beach to Miami flights
Columbia to Fort Lauderdale flights
Charlotte to Fort Myers flights
Charlotte to Jacksonville flights
Charleston to Orlando flights
Charlotte to Sarasota flights
Myrtle Beach to Orlando flights
Charlotte to Panama City flights
Charlotte to Pensacola flights
Greenville to Orlando flights
Savannah to Fort Lauderdale flights
Charleston to Key West flights
Greenville to St Petersburg flights
Greenville to Fort Lauderdale flights
Charleston to Tampa flights
Charlotte to Valparaiso flights
Columbia to Orlando flights
Charleston to West Palm Beach flights
Greenville to Tampa flights
Charlotte to Daytona Beach flights
Greenville to Fort Myers flights
Myrtle Beach to West Palm Beach flights
Columbia to Key West flights
Charleston to Fort Myers flights
Augusta to Orlando flights
Savannah to Key West flights
Columbia to Tampa flights
Greenville to Orlando Sanford Intl flights
Greenville to West Palm Beach flights
Greenville to Panama City flights
Savannah to Orlando flights
Augusta to West Palm Beach flights
Greenville to Jacksonville flights
Augusta to Key West flights
Columbia to Pensacola flights
Augusta to Miami flights
Greenville to Pensacola flights
Charlotte to Orlando Sanford Intl flights

Top 2 airlines flying from Myrtle Beach to Key West

Discover the top 2 airlines that operate flights from Myrtle Beach to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$223Average$439FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$275Average$486FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.