$138+ Cheap flights from Myrtle Beach to Key West (MYR - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — EYW
May 21 — May 281
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Key West
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Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to Key WestExplore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
Explore the most affordable flight options available from Myrtle Beach to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:30 am
MYR
- EYW
2 stops30h 37m
Multiple Airlines
Wed 5/1310:39 am
EYW
- MYR
1 stop25h 40m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/53:53 pm
MYR
- EYW
1 stop19h 34m
Breeze Airways
Thu 7/97:56 pm
EYW
- MYR
1 stop18h 10m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:42 pm
MYR
- EYW
1 stop20h 43m
Breeze Airways
Wed 5/1311:46 am
EYW
- MYR
1 stop24h 33m
Breeze Airways
Deal found 4/19![Breeze Airways logo]()
$298
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
MYR
- EYW
2 stops8h 08m
American Airlines
Wed 5/1311:24 am
EYW
- MYR
2 stops11h 00m
American Airlines
Deal found 4/17![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/42:45 pm
MYR
- EYW
1 stop7h 02m
American Airlines
Wed 11/1112:40 pm
EYW
- MYR
1 stop6h 47m
American Airlines
Deal found 4/17![American Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:58 pm
MYR
- EYW
1 stop19h 04m
Multiple Airlines
Thu 5/2812:05 pm
EYW
- MYR
1 stop21h 00m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:09 pm
MYR
- EYW
1 stop6h 27m
American Airlines
Wed 5/208:05 am
EYW
- MYR
1 stop5h 22m
American Airlines
Deal found 4/18![American Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:20 am
MYR
- EYW
2 stops24h 51m
Multiple Airlines
Thu 4/304:22 pm
EYW
- MYR
1 stop19h 58m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$317
Best flights from Myrtle Beach to Key WestDiscover carefully curated flight deals from Myrtle Beach to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
Discover carefully curated flight deals from Myrtle Beach to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:05 pm
MYR
- EYW
1 stop15h 29m
Multiple Airlines
Thu 6/189:16 pm
EYW
- MYR
2 stops22h 36m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
MYR
- EYW
1 stop4h 53m
Delta
Wed 5/207:30 am
EYW
- MYR
1 stop5h 10m
Delta
Deal found 4/16![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:28 am
MYR
- EYW
2 stops8h 11m
American Airlines
Sun 8/232:30 pm
EYW
- MYR
1 stop5h 17m
American Airlines
Deal found 4/19![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
MYR
- EYW
1 stop4h 46m
Delta
Tue 5/56:23 pm
EYW
- MYR
1 stop5h 51m
Delta
Deal found 4/16![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:00 am
MYR
- EYW
1 stop8h 37m
Multiple Airlines
Sun 8/167:56 pm
EYW
- MYR
1 stop18h 10m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:31 pm
MYR
- EYW
2 stops8h 27m
American Airlines
Sat 5/911:35 am
EYW
- MYR
2 stops10h 47m
American Airlines
Deal found 4/20![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:50 am
MYR
- EYW
1 stop5h 26m
American Airlines
Wed 6/311:28 am
EYW
- MYR
2 stops10h 19m
American Airlines
Deal found 4/18![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:30 pm
MYR
- EYW
1 stop6h 19m
Delta
Mon 6/16:19 pm
EYW
- MYR
1 stop5h 39m
Delta
Deal found 4/16![Delta logo]()
$445
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:30 pm
MYR
- EYW
1 stop6h 19m
Delta
Tue 6/96:24 pm
EYW
- MYR
1 stop5h 35m
Delta
Deal found 4/19![Delta logo]()
$489
Last-minute flights from Myrtle Beach to Key WestDiscover last-minute flight deals from Myrtle Beach to Key West. Data last updated April 21, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Key West. Data last updated April 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2810:20 am
MYR
- EYW
2 stops24h 51m
Multiple Airlines
Thu 4/304:22 pm
EYW
- MYR
1 stop19h 58m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:14 am
MYR
- EYW
1 stop6h 26m
American Airlines
Mon 5/114:20 pm
EYW
- MYR
1 stop6h 04m
American Airlines
Deal found 4/16![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:30 am
MYR
- EYW
2 stops30h 37m
Multiple Airlines
Wed 5/1310:39 am
EYW
- MYR
1 stop25h 40m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:42 pm
MYR
- EYW
1 stop20h 43m
Breeze Airways
Wed 5/1311:46 am
EYW
- MYR
1 stop24h 33m
Breeze Airways
Deal found 4/19![Breeze Airways logo]()
$298
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
MYR
- EYW
2 stops8h 08m
American Airlines
Wed 5/1311:24 am
EYW
- MYR
2 stops11h 00m
American Airlines
Deal found 4/17![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:09 pm
MYR
- EYW
1 stop6h 27m
American Airlines
Wed 5/208:05 am
EYW
- MYR
1 stop5h 22m
American Airlines
Deal found 4/18![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
MYR
- EYW
1 stop4h 53m
Delta
Wed 5/207:30 am
EYW
- MYR
1 stop5h 10m
Delta
Deal found 4/16![Delta logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:58 pm
MYR
- EYW
1 stop19h 04m
Multiple Airlines
Thu 5/2812:05 pm
EYW
- MYR
1 stop21h 00m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$305
One-way flights from Myrtle Beach to Key WestSearch for one-way flight options from Myrtle Beach to Key West. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
Search for one-way flight options from Myrtle Beach to Key West. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/283:53 pm
MYR
- EYW
1 stop19h 34m
Breeze Airways
Deal found 4/17![Breeze Airways logo]()
$138
This Priceline deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MYR
- EYW
1 stop7h 35m
Spirit Airlines
Deal found 4/19![Spirit Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2811:55 am
MYR
- EYW
2 stops27h 50m
Allegiant Air
Deal found 4/17![Allegiant Air logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
MYR
- EYW
3 stops53h 06m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:03 pm
MYR
- EYW
2 stops38h 22m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$212
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:51 pm
MYR
- EYW
1 stop6h 02m
Delta
Deal found 4/16![Delta logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:10 pm
MYR
- EYW
3 stops40h 24m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:43 pm
MYR
- EYW
1 stop5h 57m
Delta
Deal found 4/20![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:00 am
MYR
- EYW
2 stops5h 54m
American Airlines
Deal found 4/20![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:14 pm
MYR
- EYW
3 stops24h 48m
United Airlines
Deal found 4/19![United Airlines logo]()
$725
Find flight deals from Myrtle Beach to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (Kiwi.com) |
One-way from | $138 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $542 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Mon 6/15
9:05 pm-12:34 pm
1 stop15h 29m
Key West
Thu 6/18
9:16 pm-7:52 pm
2 stops22h 36m
$324
Quickest round-trip
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Wed 5/13
6:00 am-10:53 am
1 stop4h 53m
Key West
Wed 5/20
7:30 am-12:40 pm
1 stop5h 10m
$329
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/1
6:00 am-10:46 am
1 stop4h 46m
Key West
Tue 5/5
6:23 pm-12:14 am
1 stop5h 51m
$339
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 8/20
11:28 am-7:39 pm
2 stops8h 11m
Key West
Sun 8/23
2:30 pm-7:47 pm
1 stop5h 17m
$414
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 8/14
10:00 am-6:37 pm
1 stop8h 37m
Key West
Sun 8/16
7:56 pm-2:06 pm
1 stop18h 10m
$422
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Tue 5/5
2:31 pm-10:58 pm
2 stops8h 27m
Key West
Sat 5/9
11:35 am-10:22 pm
2 stops10h 47m
$435
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/29
6:50 am-12:16 pm
1 stop5h 26m
Key West
Wed 6/3
11:28 am-9:47 pm
2 stops10h 19m
$443
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Wed 5/20
1:30 pm-7:49 pm
1 stop6h 19m
Key West
Mon 6/1
6:19 pm-11:58 pm
1 stop5h 39m
$445
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 6/4
1:30 pm-7:49 pm
1 stop6h 19m
Key West
Tue 6/9
6:24 pm-11:59 pm
1 stop5h 35m
$489
Cheapest one-way
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sun 6/28
3:53 pm-11:27 am
1 stop19h 34m
$138
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Key West in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Myrtle Beach with our price prediction graph.
MYR-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Key West
What is the cheapest month to book a flight from Myrtle Beach to Key West?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Key West (average of $335). Flying from Myrtle Beach to Key West in March is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 21, 2026.
See what other customers who have flown with Delta and American Airlines from Myrtle Beach to Key West have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Overall
7.9
Crew
8.5
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentMatthew,Oct 2025
GSP - ATL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 21, 2026.
Myrtle Beach and Key West flights
Browse other Myrtle Beach and Key West flight options. Last updated on April 21, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on April 21, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Key West
Discover the top 2 airlines that operate flights from Myrtle Beach to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$258 | Average$441 | FlexibilityNo cancel fee | On-time71% |