$185+ Cheap flights from Roanoke to Key West (ROA - EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
May 11 — May 181
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Key West
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Cheapest flights from Roanoke to Key WestExplore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
Explore the most affordable flight options available from Roanoke to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Thu 5/711:04 am
EYW
- ROA
1 stop8h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:10 am
ROA
- EYW
2 stops10h 37m
American Airlines
Wed 7/297:29 pm
EYW
- ROA
1 stop4h 26m
American Airlines
Deal found 4/10![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:58 pm
ROA
- EYW
2 stops10h 00m
American Airlines
Tue 5/196:45 am
EYW
- ROA
2 stops10h 48m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:18 pm
ROA
- EYW
1 stop5h 18m
American Airlines
Wed 4/2911:56 am
EYW
- ROA
1 stop7h 09m
American Airlines
Deal found 4/10![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
ROA
- EYW
1 stop4h 58m
Delta
Wed 10/146:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:10 am
ROA
- EYW
2 stops10h 37m
American Airlines
Wed 8/53:00 pm
EYW
- ROA
1 stop4h 53m
American Airlines
Deal found 4/8![American Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:58 pm
ROA
- EYW
1 stop22h 45m
Allegiant Air
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$370
Best flights from Roanoke to Key WestDiscover carefully curated flight deals from Roanoke to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
Discover carefully curated flight deals from Roanoke to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:10 am
ROA
- EYW
2 stops10h 37m
American Airlines
Wed 7/297:29 pm
EYW
- ROA
1 stop4h 26m
American Airlines
Deal found 4/10![American Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:38 pm
ROA
- EYW
2 stops19h 03m
Allegiant Air
Sun 6/219:16 pm
EYW
- ROA
1 stop18h 02m
Allegiant Air
Deal found 4/10![Allegiant Air logo]()
$437
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:10 am
ROA
- EYW
2 stops10h 39m
American Airlines
Tue 6/27:29 pm
EYW
- ROA
1 stop4h 18m
American Airlines
Deal found 4/9![American Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
ROA
- EYW
1 stop4h 53m
Delta
Tue 6/26:19 pm
EYW
- ROA
1 stop6h 15m
Delta
Deal found 4/9![Delta logo]()
$411
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
ROA
- EYW
1 stop4h 58m
Delta
Thu 10/156:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
ROA
- EYW
1 stop4h 58m
Delta
Sat 10/176:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$431
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:00 am
ROA
- EYW
1 stop5h 16m
American Airlines
Tue 6/27:29 pm
EYW
- ROA
1 stop4h 18m
American Airlines
Deal found 4/7![American Airlines logo]()
$530
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am
ROA
- EYW
2 stops12h 43m
Delta
Tue 10/136:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$520
Last-minute flights from Roanoke to Key WestDiscover last-minute flight deals from Roanoke to Key West. Data last updated April 11, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Key West. Data last updated April 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:58 pm
ROA
- EYW
1 stop22h 45m
Allegiant Air
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Allegiant Air
Deal found 4/7![Allegiant Air logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:58 pm
ROA
- EYW
1 stop22h 45m
Multiple Airlines
Thu 5/711:04 am
EYW
- ROA
1 stop8h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Thu 5/711:04 am
EYW
- ROA
1 stop8h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:09 am
ROA
- EYW
1 stop5h 40m
American Airlines
Fri 5/14:20 pm
EYW
- ROA
1 stop6h 06m
American Airlines
Deal found 4/10![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:18 pm
ROA
- EYW
1 stop5h 18m
American Airlines
Wed 4/2911:56 am
EYW
- ROA
1 stop7h 09m
American Airlines
Deal found 4/10![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:58 pm
ROA
- EYW
2 stops10h 00m
American Airlines
Tue 5/196:45 am
EYW
- ROA
2 stops10h 48m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
One-way flights from Roanoke to Key WestSearch for one-way flight options from Roanoke to Key West. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
Search for one-way flight options from Roanoke to Key West. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:23 pm
ROA
- EYW
1 stop18h 23m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$185
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:00 am
ROA
- EYW
2 stops8h 07m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
Find flight deals from Roanoke to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $323 (Delta) |
One-way from | $185 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $490 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Roanoke to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/12
7:05 am-1:42 pm
1 stop6h 37m
Key West
Tue 5/19
2:32 pm-11:00 pm
1 stop8h 28m
$323
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Sat 7/25
8:10 am-6:47 pm
2 stops10h 37m
Key West
Wed 7/29
7:29 pm-11:55 pm
1 stop4h 26m
$328
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/26
8:10 am-6:49 pm
2 stops10h 39m
Key West
Tue 6/2
7:29 pm-11:47 pm
1 stop4h 18m
$391
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/26
6:00 am-10:53 am
1 stop4h 53m
Key West
Tue 6/2
6:19 pm-12:34 am
1 stop6h 15m
$411
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Wed 10/7
6:00 am-10:58 am
1 stop4h 58m
Key West
Thu 10/15
6:00 pm-11:49 pm
1 stop5h 49m
$426
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 10/6
6:00 am-10:58 am
1 stop4h 58m
Key West
Sat 10/17
6:00 pm-11:49 pm
1 stop5h 49m
$431
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Thu 6/18
2:38 pm-9:41 am
2 stops19h 03m
Key West
Sun 6/21
9:16 pm-3:18 pm
1 stop18h 02m
$437
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 10/6
7:00 am-7:43 pm
2 stops12h 43m
Key West
Tue 10/13
6:00 pm-11:49 pm
1 stop5h 49m
$520
Quickest round-trip
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Thu 5/28
7:00 am-12:16 pm
1 stop5h 16m
Key West
Tue 6/2
7:29 pm-11:47 pm
1 stop4h 18m
$530
Cheapest one-way
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Sun 5/24
9:23 pm-3:46 pm
1 stop18h 23m
$185
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Key West in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Roanoke with our price prediction graph.
ROA-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Key West
What is the cheapest month to book a flight from Roanoke to Key West?
Currently, February is the cheapest month in which you can book a flight from Roanoke to Key West (average of $233). Flying from Roanoke to Key West in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Roanoke to Key West?
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 11, 2026.
Read through reviews of airlines operating flights from Roanoke to Key West, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Overall
7.9
Food
7.2
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Overall
7.9
Food
7.2
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Crew
8.5
Overall
7.9
Food
7.2
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Search flights from Roanoke to Key West by cabin class
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 11, 2026.
Roanoke and Key West flights
Browse other Roanoke and Key West flight options. Last updated on April 11, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on April 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Roanoke to Key West
Discover the top 2 airlines that operate flights from Roanoke to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$465 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$473 | FlexibilityNo cancel fee | On-timeN/A |