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Key West

$288+ Cheap flights from Sioux Falls to Key West (FSD - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Mar 18 — Mar 251
Wed 3/18
Wed 3/25
1 adult, Economy
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Cheap flight deals from Sioux Falls to Key West

Cheapest flights from Sioux Falls to Key West
Explore the most affordable flight options available from Sioux Falls to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 16, 2026.

This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:29 pm
FSD
-
EYW
2 stops9h 29m
American Airlines
Tue 5/122:29 pm
EYW
-
FSD
1 stop8h 25m
American Airlines
Deal found 2/14$288
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:09 pm
FSD
-
EYW
2 stops17h 12m
Multiple Airlines
Fri 3/63:43 pm
EYW
-
FSD
1 stop23h 03m
Multiple Airlines
Deal found 2/15$319
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:44 am
FSD
-
EYW
2 stops12h 28m
American Airlines
Wed 4/12:25 pm
EYW
-
FSD
1 stop8h 15m
American Airlines
Deal found 2/16$341
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:40 am
FSD
-
EYW
1 stop6h 26m
United Airlines
Wed 9/237:00 am
EYW
-
FSD
1 stop8h 35m
United Airlines
Deal found 2/12$373
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:14 pm
FSD
-
EYW
2 stops9h 08m
American Airlines
Wed 3/42:45 pm
EYW
-
FSD
1 stop7h 55m
American Airlines
Deal found 2/13$379
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:41 pm
FSD
-
EYW
2 stops8h 17m
American Airlines
Tue 5/122:29 pm
EYW
-
FSD
1 stop8h 25m
American Airlines
Deal found 2/13$391
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:02 pm
FSD
-
EYW
1 stop17h 59m
Allegiant Air
Wed 6/35:07 pm
EYW
-
FSD
2 stops41h 00m
Allegiant Air
Deal found 2/15$394
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:45 am
FSD
-
EYW
1 stop23h 19m
Allegiant Air
Sun 5/103:19 pm
EYW
-
FSD
1 stop19h 36m
Allegiant Air
Deal found 2/13$398

Find flight deals from Sioux Falls to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$288
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$657
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Key West flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Key West flights.
Search Deals
From Sioux Falls Joe Foss Field to Key West
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.

Fly from

Sioux Falls

Fly to

Key West

Route

Depart

Return

Price

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

12:29 pm-10:58 pm

2 stops9h 29m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$288

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 3/24

12:14 pm-10:18 pm

2 stops9h 04m

Key West

Wed 4/1

2:25 pm-9:40 pm

1 stop8h 15m

$341

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 5/8

1:41 pm-10:58 pm

2 stops8h 17m

Key West

Tue 5/12

2:29 pm-9:54 pm

1 stop8h 25m

$391

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Mon 5/11

1:41 pm-10:58 pm

2 stops8h 17m

Key West

Sat 5/16

1:08 pm-7:09 pm

1 stop7h 01m

$440

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Tue 5/5

6:45 am-4:30 pm

2 stops8h 45m

Key West

Sat 5/9

1:08 pm-7:09 pm

1 stop7h 01m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Compare providers for flights from Sioux Falls to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Key West in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated February 16, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Sioux Falls to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,299 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,299 reviews
United Airlines
7.4
Good
9,299 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,294 reviews
United Airlines
7.4
Good
9,299 reviews

Boarding

7.7

Entertainment

7.1

Overall

7.4

Food

6.6

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Key West?

    There are many flights that can get you from Sioux Falls to Key West in 9h 29m. Fly via American Airlines to get the fastest option. The distance from Sioux Falls to Key West is about 1563 mi.

  • What are the cheapest airlines flying from Sioux Falls to Key West round-trip?

    Flying on American Airlines is currently your cheapest option to Key West, with prices starting at $288. Another option worth looking into is United Airlines, starting at $490 round trip. You may be able to fly from Sioux Falls to Key West for 44% less than the average price by searching for these airlines.

  • Can I find deals for flights from Sioux Falls to Key West that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Key West.

  • Can I find deals for business class flights from Sioux Falls to Key West?

    Yes. Cheapflights offers flight deals from Sioux Falls to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Sioux Falls to Key West

Discover the top 2 airlines that operate flights from Sioux Falls to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$444FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$490Average$714FlexibilityNo cancel feeOn-time69%

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