$249+ Cheap flights from Sioux Falls to Key West (FSD - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Key West
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Best
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One-way
Cheapest flights from Sioux Falls to Key WestExplore the most affordable flight options available from Sioux Falls to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Sioux Falls to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 am -
2 stops8h 53m
Sat 10/312:34 pm -
1 stop7h 39m
Deal found 9/10![American Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:45 pm -
1 stop15h 34m
Sun 11/19:12 am -
1 stop25h 27m
Deal found 9/10![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:59 am -
1 stop22h 03m
Sun 11/19:12 am -
1 stop25h 27m
Deal found 9/6![Allegiant Air logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:20 am -
2 stops9h 38m
Wed 10/281:43 pm -
2 stops11h 58m
Deal found 9/9![American Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:45 pm -
1 stop12h 54m
Sun 11/18:36 pm -
2 stops24h 13m
Deal found 9/10![Allegiant Air logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:14 pm -
1 stop14h 05m
Thu 11/123:03 pm -
2 stops28h 20m
Deal found 9/7![Multiple Airlines logo]()
$410
Best flights from Sioux Falls to Key WestDiscover carefully curated flight deals from Sioux Falls to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Sioux Falls to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 am -
2 stops8h 53m
Sat 10/312:34 pm -
1 stop7h 39m
Deal found 9/10![American Airlines logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:40 am -
1 stop8h 30m
Wed 1/135:51 pm -
1 stop6h 59m
Deal found 9/7![United Airlines logo]()
$453
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/234:09 pm -
2 stops24h 02m
Thu 1/287:00 am -
2 stops9h 50m
Deal found 9/7![Delta logo]()
$565
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 am -
1 stop6h 23m
Sat 9/262:00 pm -
2 stops9h 51m
Deal found 9/7![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2310:58 am -
2 stops7h 45m
Wed 1/276:00 pm -
2 stops19h 11m
Deal found 9/7![Delta logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:50 am -
1 stop6h 34m
Sat 10/104:20 pm -
1 stop7h 51m
Deal found 9/6![United Airlines logo]()
$753
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:48 am -
1 stop6h 41m
Sat 10/314:10 pm -
1 stop6h 27m
Deal found 9/8![United Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:00 am -
1 stop9h 24m
Wed 12/306:20 pm -
1 stop6h 21m
Deal found 9/6![Delta logo]()
$843
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:48 am -
1 stop6h 41m
Thu 11/54:10 pm -
1 stop6h 27m
Deal found 9/7![United Airlines logo]()
$861
Last-minute flights from Sioux Falls to Key WestDiscover last-minute flight deals from Sioux Falls to Key West. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Key West. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:20 am -
2 stops9h 38m
Wed 10/281:43 pm -
2 stops11h 58m
Deal found 9/9![American Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:05 am -
2 stops8h 53m
Sat 10/312:34 pm -
1 stop7h 39m
Deal found 9/10![American Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:45 pm -
1 stop12h 54m
Sun 11/19:12 am -
1 stop25h 27m
Deal found 9/10![Allegiant Air logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:45 pm -
1 stop15h 34m
Sun 11/18:36 pm -
2 stops24h 13m
Deal found 9/10![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:59 am -
1 stop22h 03m
Sun 11/19:12 am -
1 stop25h 27m
Deal found 9/6![Allegiant Air logo]()
$370
One-way flights from Sioux Falls to Key WestSearch for one-way flight options from Sioux Falls to Key West. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Sioux Falls to Key West. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/156:27 pm -
2 stops40h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/157:40 am -
1 stop5h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/279:00 am -
2 stops26h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$673
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2710:33 am -
3 stops32h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Allegiant Air logo]()
$735
Find flight deals from Sioux Falls to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $338 (American Airlines) |
One-way from | $249 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $578 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Wed 10/28
7:05 am-4:58 pm
2 stops8h 53m
Key West
Sat 10/31
2:34 pm-9:13 pm
1 stop7h 39m
$338
Quickest round-trip
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Mon 2/15
7:40 am-2:36 pm
1 stop5h 56m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$389
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Tue 1/5
7:40 am-5:10 pm
1 stop8h 30m
Key West
Wed 1/13
5:51 pm-11:50 pm
1 stop6h 59m
$453
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 1/23
4:09 pm-5:11 pm
2 stops24h 02m
Key West
Thu 1/28
7:00 am-3:50 pm
2 stops9h 50m
$565
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Tue 9/22
5:30 am-12:53 pm
1 stop6h 23m
Key West
Sat 9/26
2:00 pm-10:51 pm
2 stops9h 51m
$584
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 1/23
10:58 am-7:43 pm
2 stops7h 45m
Key West
Wed 1/27
6:00 pm-12:11 pm
2 stops19h 11m
$613
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sun 12/27
9:00 am-12:07 pm
2 stops26h 07m
Key West
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$673
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 10/3
7:50 am-3:24 pm
1 stop6h 34m
Key West
Sat 10/10
4:20 pm-11:11 pm
1 stop7h 51m
$753
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Wed 10/28
7:48 am-3:29 pm
1 stop6h 41m
Key West
Sat 10/31
4:10 pm-9:37 pm
1 stop6h 27m
$799
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Fri 12/25
7:00 am-5:24 pm
1 stop9h 24m
Key West
Wed 12/30
6:20 pm-11:41 pm
1 stop6h 21m
$843
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Key West in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Sioux Falls with our price prediction graph.
FSD-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Key West
What is the cheapest month to book a flight from Sioux Falls to Key West?
Currently, April is the cheapest month in which you can book a flight from Sioux Falls to Key West (average of $408). Flying from Sioux Falls to Key West in December is currently the most expensive (average of $1,105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to Key West?
Airfare is below average for this route at the moment.
Sioux Falls to Key West flights typically cost between $515 and $888 in January.The cheapest round-trip price found within the last 5 days was $327 on Multiple Airlines (Jan 4-Jan 14).
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Crew
8.5
Entertainment
7.8
Comfort
7.8
Overall
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Sioux Falls and Key West flights
Browse other Sioux Falls and Key West flight options. Last updated on September 10, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Sioux Falls to Key West
Discover the top 3 airlines that operate flights from Sioux Falls to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$341 | Average$492 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$372 | Average$515 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$456 | Average$793 | FlexibilityNo cancel fee | On-time69% |