$472+ Cheap flights from Sioux Falls to Key West (FSD - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Sioux Falls to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Key West
Cheapest
Best
Last-minute
Cheapest flights from Sioux Falls to Key WestExplore the most affordable flight options available from Sioux Falls to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Sioux Falls to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop6h 23m
Sat 10/314:00 pm -
2 stops8h 03m
Deal found 10/20![Delta logo]()
$484
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:38 pm -
2 stops13h 46m
Sat 11/215:18 pm -
1 stop17h 23m
Deal found 10/20![Multiple Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop8h 29m
Sat 10/314:10 pm -
1 stop6h 27m
Deal found 10/21![United Airlines logo]()
$743
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:05 am -
2 stops11h 05m
Sat 11/217:30 am -
2 stops9h 28m
Deal found 10/20![Delta logo]()
$904
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop8h 29m
Sat 11/214:10 pm -
1 stop6h 27m
Deal found 10/20![United Airlines logo]()
$971
Best flights from Sioux Falls to Key WestDiscover carefully curated flight deals from Sioux Falls to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Sioux Falls to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/105:03 am -
2 stops11h 23m
Sat 1/231:53 pm -
2 stops11h 44m
Deal found 10/22![American Airlines logo]()
$472
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/296:35 am -
1 stop8h 29m
Tue 2/22:50 pm -
1 stop5h 57m
Deal found 10/24![Delta logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:38 pm -
2 stops13h 46m
Sat 11/215:18 pm -
1 stop17h 23m
Deal found 10/20![Multiple Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:30 am -
3 stops29h 43m
Wed 2/34:09 pm -
1 stop7h 12m
Deal found 10/23![United Airlines logo]()
$758
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/297:00 am -
1 stop8h 52m
Mon 2/11:52 pm -
2 stops11h 34m
Deal found 10/24![American Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/236:45 am -
1 stop5h 23m
Wed 3/32:35 pm -
1 stop6h 06m
Deal found 10/23![Delta logo]()
$608
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:00 am -
1 stop8h 52m
Tue 2/21:52 pm -
2 stops11h 34m
Deal found 10/24![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/155:15 pm -
1 stop17h 09m
Fri 2/197:39 pm -
2 stops17h 04m
Deal found 10/20![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:03 am -
2 stops13h 33m
Sat 2/69:58 am -
2 stops11h 56m
Deal found 10/24![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/205:03 am -
2 stops12h 37m
Fri 2/267:39 pm -
2 stops17h 04m
Deal found 10/24![American Airlines logo]()
$656
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:00 am -
1 stop8h 52m
Mon 2/19:58 am -
2 stops9h 58m
Deal found 10/24![American Airlines logo]()
$714
Last-minute flights from Sioux Falls to Key WestDiscover last-minute flight deals from Sioux Falls to Key West. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Key West. Data last updated October 25, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop6h 23m
Sat 10/314:00 pm -
2 stops8h 03m
Deal found 10/20![Delta logo]()
$484
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 am -
1 stop8h 29m
Sat 10/314:10 pm -
1 stop6h 27m
Deal found 10/21![United Airlines logo]()
$743
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:38 pm -
2 stops13h 46m
Sat 11/215:18 pm -
1 stop17h 23m
Deal found 10/20![Multiple Airlines logo]()
$514
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:05 am -
2 stops11h 05m
Sat 11/217:30 am -
2 stops9h 28m
Deal found 10/20![Delta logo]()
$904
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop8h 29m
Sat 11/214:10 pm -
1 stop6h 27m
Deal found 10/20![United Airlines logo]()
$971
Find flight deals from Sioux Falls to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $333 (Kiwi.com) |
Popular in | November |
Cheapest in | April |
Average price | $533 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Sioux Falls to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sun 1/10
5:03 am-5:26 pm
2 stops11h 23m
Key West
Sat 1/23
1:53 pm-12:37 am
2 stops11h 44m
$472
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Fri 1/29
6:35 am-4:04 pm
1 stop8h 29m
Key West
Tue 2/2
2:50 pm-7:47 pm
1 stop5h 57m
$499
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Fri 1/29
7:00 am-4:52 pm
1 stop8h 52m
Key West
Mon 2/1
1:52 pm-12:26 am
2 stops11h 34m
$511
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Fri 11/20
6:38 pm-9:24 am
2 stops13h 46m
Key West
Sat 11/21
5:18 pm-9:41 am
1 stop17h 23m
$514
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 1/30
7:00 am-4:52 pm
1 stop8h 52m
Key West
Tue 2/2
1:52 pm-12:26 am
2 stops11h 34m
$587
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Mon 2/15
5:15 pm-11:24 am
1 stop17h 09m
Key West
Fri 2/19
7:39 pm-11:43 am
2 stops17h 04m
$606
Quickest round-trip
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Tue 2/23
6:45 am-1:08 pm
1 stop5h 23m
Key West
Wed 3/3
2:35 pm-7:41 pm
1 stop6h 06m
$608
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 1/30
5:03 am-7:36 pm
2 stops13h 33m
Key West
Sat 2/6
9:58 am-8:54 pm
2 stops11h 56m
$631
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 2/20
5:03 am-6:40 pm
2 stops12h 37m
Key West
Fri 2/26
7:39 pm-11:43 am
2 stops17h 04m
$656
Sioux FallsKey West
FSD Sioux Falls Joe Foss Field - EYW Key West
FSDEYW
Sioux Falls Joe Foss Field
Sat 1/30
7:00 am-4:52 pm
1 stop8h 52m
Key West
Mon 2/1
9:58 am-6:56 pm
2 stops9h 58m
$714
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Key West in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Sioux Falls with our price prediction graph.
FSD-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated October 25, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Sioux Falls to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Search flights from Sioux Falls to Key West by cabin class
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Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Sioux Falls and Key West flights
Browse other Sioux Falls and Key West flight options. Last updated on October 25, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Sioux Falls to Key West
Discover the top 3 airlines that operate flights from Sioux Falls to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$341 | Average$487 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$374 | Average$533 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$456 | Average$793 | FlexibilityNo cancel fee | On-time69% |