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Panama City

$301+ Cheap flights from Sioux Falls to Panama City, FL (FSD - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — ECP
Aug 25 — Sep 11
Tue 8/25
Tue 9/1
1 adult, Economy
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Cheap flight deals from Sioux Falls to Panama City

Cheapest flights from Sioux Falls to Panama City
Explore the most affordable flight options available from Sioux Falls to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.

This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am
FSD
-
ECP
1 stop5h 42m
American Airlines
Sat 9/263:17 pm
ECP
-
FSD
1 stop5h 28m
American Airlines
Deal found 7/25$301
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:08 pm
FSD
-
ECP
1 stop7h 51m
American Airlines
Tue 11/108:19 am
ECP
-
FSD
2 stops10h 42m
American Airlines
Deal found 7/25$345
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:53 pm
FSD
-
ECP
2 stops11h 00m
American Airlines
Sat 10/247:15 am
ECP
-
FSD
2 stops11h 50m
American Airlines
Deal found 7/21$354
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:50 am
FSD
-
ECP
1 stop5h 13m
United Airlines
Sat 10/244:16 pm
ECP
-
FSD
1 stop6h 55m
United Airlines
Deal found 7/21$377
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:09 pm
FSD
-
ECP
1 stop8h 07m
American Airlines
Tue 12/86:33 am
ECP
-
FSD
1 stop5h 49m
American Airlines
Deal found 7/23$380

Find flight deals from Sioux Falls to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$301
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$445
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flights.
Search Deals
From Sioux Falls Joe Foss Field to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($303 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 18% potential price decrease ($88 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Sioux Falls to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 11/6

1:08 pm-8:59 pm

1 stop7h 51m

Panama City NW Florida Beaches

Tue 11/10

8:19 am-7:01 pm

2 stops10h 42m

$345

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sat 10/17

7:50 am-1:03 pm

1 stop5h 13m

Panama City NW Florida Beaches

Sat 10/24

4:16 pm-11:11 pm

1 stop6h 55m

$377

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 9/22

1:05 pm-11:05 pm

2 stops10h 00m

Panama City NW Florida Beaches

Sat 9/26

6:00 am-12:19 pm

2 stops6h 19m

$385

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sat 8/29

7:47 am-4:38 pm

2 stops8h 51m

Panama City NW Florida Beaches

Tue 9/1

11:41 am-11:22 pm

2 stops11h 41m

$391

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 8/18

6:24 am-2:30 pm

1 stop8h 06m

Panama City NW Florida Beaches

Mon 8/24

11:42 am-12:30 am

2 stops12h 48m

$404
Quickest round-trip

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 12/11

5:25 am-10:15 am

1 stop4h 50m

Panama City NW Florida Beaches

Mon 12/14

4:10 pm-10:12 pm

1 stop6h 02m

$449

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 11/6

7:30 am-1:44 pm

1 stop6h 14m

Panama City NW Florida Beaches

Tue 11/10

2:25 pm-9:45 pm

1 stop7h 20m

$455
Cheapest one-way
Quickest one-way

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 12/11

1:09 pm-9:16 pm

1 stop8h 07m

$309

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Fri 12/11

7:40 am-8:06 pm

3 stops12h 26m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Sorted by cheapest first

Compare providers for flights from Sioux Falls to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Panama City in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 26, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Sioux Falls to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,487 reviews

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.
Delta
7.8
Good
8,487 reviews
Delta
7.8
Good
8,487 reviews

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.
American Airlines
7.1
Good
11,844 reviews
Delta
7.8
Good
8,487 reviews

Boarding

8.1

Overall

7.8

Entertainment

7.8

Comfort

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
4.0
Okay

Joel,May 2026

ATL - JAX

The flight was delivered 50 minutes and taxing took what felt like 20 minutes to takeoff.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Panama City, Florida?

    American Airlines, United Airlines, and Delta can get you from Sioux Falls to Panama City, Florida in just under 5h 13m. Your travel time can differ by up to 4h 47m. Sioux Falls and Panama City, Florida are separated by a distance of 1092 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Sioux Falls to Panama City, Florida round-trip?

    American Airlines, at $279, was found to be the cheapest airline from Sioux Falls to Panama City, Florida. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 51% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Panama City that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Panama City.

  • Can I find deals for business class flights from Sioux Falls to Panama City?

    Yes. Cheapflights offers flight deals from Sioux Falls to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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Top 2 airlines flying from Sioux Falls to Panama City

Discover the top 2 airlines that operate flights from Sioux Falls to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$279Average$398FlexibilityNo cancel feeOn-time71%
DeltaCheapest$310Average$418FlexibilityNo cancel feeOn-timeN/A

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