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Panama City

$291+ Cheap flights from Sioux Falls to Panama City, FL (FSD - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — ECP
Jul 12 — Jul 191
Sun 7/12
Sun 7/19
1 adult, Economy
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Cheap flight deals from Sioux Falls to Panama City

Cheapest flights from Sioux Falls to Panama City
Explore the most affordable flight options available from Sioux Falls to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.

This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:30 am
FSD
-
ECP
1 stop7h 10m
Delta
Sat 9/261:47 pm
ECP
-
FSD
1 stop6h 02m
Delta
Deal found 6/8$291
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am
FSD
-
ECP
1 stop6h 55m
American Airlines
Sun 9/63:15 pm
ECP
-
FSD
1 stop6h 52m
American Airlines
Deal found 6/7$310
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:35 am
FSD
-
ECP
2 stops10h 43m
United Airlines
Sat 10/243:30 pm
ECP
-
FSD
1 stop8h 14m
United Airlines
Deal found 6/9$340
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am
FSD
-
ECP
2 stops11h 32m
American Airlines
Sat 9/268:29 am
ECP
-
FSD
2 stops9h 42m
American Airlines
Deal found 6/8$351
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:30 am
FSD
-
ECP
1 stop6h 55m
American Airlines
Sat 10/243:17 pm
ECP
-
FSD
1 stop6h 38m
American Airlines
Deal found 6/9$373

Find flight deals from Sioux Falls to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(Delta)

Popular in

May

Cheapest in

March

Average price

$381
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Panama City NW Florida Beaches flights.
Search Deals
From Sioux Falls Joe Foss Field to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($114 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Sioux Falls to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 9/22

5:30 am-12:40 pm

1 stop7h 10m

Panama City NW Florida Beaches

Sat 9/26

1:47 pm-7:49 pm

1 stop6h 02m

$291

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Wed 9/2

7:30 am-2:25 pm

1 stop6h 55m

Panama City NW Florida Beaches

Sun 9/6

3:15 pm-10:07 pm

1 stop6h 52m

$310

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Tue 9/22

6:00 am-5:32 pm

2 stops11h 32m

Panama City NW Florida Beaches

Sat 9/26

8:29 am-6:11 pm

2 stops9h 42m

$345
Cheapest one-way

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sun 11/15

5:15 am-5:50 pm

2 stops12h 35m

$309
Quickest one-way

Sioux FallsPanama City

FSD - ECP

FSDECP

Sioux Falls Joe Foss Field

Sun 11/15

6:00 am-4:17 pm

3 stops10h 17m

$591

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Sorted by cheapest first

Compare providers for flights from Sioux Falls to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Panama City in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated June 12, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Sioux Falls to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,403 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,403 reviews
Delta
7.9
Good
8,403 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,642 reviews
Delta
7.9
Good
8,403 reviews

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Panama City, Florida?

    Delta can get you from Sioux Falls to Panama City, Florida in just under 7h 10m. Your travel time can differ by up to . Sioux Falls and Panama City, Florida are separated by a distance of 1092 mi.

  • What are the cheapest airlines flying from Sioux Falls to Panama City, Florida round-trip?

    American Airlines, at $279, was found to be the cheapest airline from Sioux Falls to Panama City, Florida. An alternate airline flying to your destination would be Delta. American Airlines is currently priced 38% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Panama City that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Panama City.

  • Can I find deals for business class flights from Sioux Falls to Panama City?

    Yes. Cheapflights offers flight deals from Sioux Falls to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Sioux Falls to Panama City

Discover the top 2 airlines that operate flights from Sioux Falls to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$279Average$398FlexibilityNo cancel feeOn-time71%
DeltaCheapest$303Average$418FlexibilityNo cancel feeOn-timeN/A

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