$309+ Cheap flights from Charleston, WV to Key West (CRW - EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
CRW — EYW
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Key West
Cheapest
Best
Last-minute
Cheapest flights from Charleston to Key WestExplore the most affordable flight options available from Charleston to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Charleston to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:11 am -
1 stop6h 04m
Wed 11/116:05 pm -
1 stop5h 38m
Deal found 9/4![Delta logo]()
$309
This deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:11 am -
1 stop6h 04m
Fri 11/137:25 am -
1 stop6h 30m
Deal found 9/4![Delta logo]()
$338
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:33 pm -
1 stop5h 27m
Thu 10/86:10 pm -
1 stop5h 20m
Deal found 9/3![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:35 pm -
1 stop5h 25m
Tue 11/176:05 pm -
1 stop5h 38m
Deal found 9/2![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am -
1 stop4h 47m
Tue 11/176:05 pm -
1 stop5h 38m
Deal found 9/2![Delta logo]()
$373
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:34 pm -
1 stop5h 22m
Thu 11/197:18 pm -
1 stop4h 45m
Deal found 8/31![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:45 pm -
1 stop5h 10m
Tue 9/2211:30 am -
2 stops7h 49m
Deal found 9/2![American Airlines logo]()
$394
Best flights from Charleston to Key WestDiscover carefully curated flight deals from Charleston to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Charleston to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:33 pm -
1 stop5h 27m
Thu 10/86:10 pm -
1 stop5h 20m
Deal found 9/3![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:34 pm -
1 stop5h 22m
Thu 11/197:18 pm -
1 stop4h 45m
Deal found 8/31![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:35 pm -
1 stop5h 25m
Tue 11/176:05 pm -
1 stop5h 38m
Deal found 9/2![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am -
1 stop4h 47m
Tue 11/176:05 pm -
1 stop5h 38m
Deal found 9/2![Delta logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:45 pm -
1 stop5h 10m
Tue 9/2212:45 pm -
1 stop6h 34m
Deal found 9/2![American Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:34 pm -
1 stop5h 27m
Sat 12/51:52 pm -
1 stop4h 46m
Deal found 9/1![American Airlines logo]()
$458
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:35 pm -
1 stop5h 25m
Tue 11/176:05 pm -
1 stop5h 38m
Deal found 9/2![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:33 pm -
1 stop5h 27m
Mon 9/216:19 pm -
1 stop5h 01m
Deal found 9/2![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:05 am -
2 stops10h 22m
Sat 11/217:16 pm -
1 stop4h 47m
Deal found 9/1![American Airlines logo]()
$543
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:35 pm -
1 stop5h 25m
Fri 11/137:25 am -
1 stop27h 15m
Deal found 9/2![Delta logo]()
$507
Last-minute flights from Charleston to Key WestDiscover last-minute flight deals from Charleston to Key West. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Key West. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:21 am -
1 stop6h 34m
Tue 9/812:06 pm -
1 stop6h 19m
Deal found 9/3![American Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:45 pm -
1 stop5h 10m
Tue 9/2211:30 am -
2 stops7h 49m
Deal found 9/2![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:33 pm -
1 stop5h 27m
Mon 9/216:19 pm -
1 stop5h 01m
Deal found 9/2![Delta logo]()
$448
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:45 pm -
1 stop5h 10m
Mon 9/2110:21 am -
2 stops8h 58m
Deal found 9/2![American Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:33 pm -
1 stop5h 27m
Thu 10/86:10 pm -
1 stop5h 20m
Deal found 9/3![Delta logo]()
$343
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:00 am -
1 stop4h 47m
Sat 10/1711:38 am -
1 stop4h 12m
Deal found 9/2![Delta logo]()
$493
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:01 am -
2 stops8h 02m
Sat 10/1712:29 pm -
1 stop7h 00m
Deal found 9/2![American Airlines logo]()
$589
Find flight deals from Charleston to Key West
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CRW) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 |
Popular in | March |
Cheapest in | January |
Average price | $486 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Charleston to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Fri 10/2
2:33 pm-8:00 pm
1 stop5h 27m
Key West
Thu 10/8
6:10 pm-11:30 pm
1 stop5h 20m
$343
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Tue 11/10
2:35 pm-8:00 pm
1 stop5h 25m
Key West
Tue 11/17
6:05 pm-11:43 pm
1 stop5h 38m
$344
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Fri 11/6
6:00 am-10:47 am
1 stop4h 47m
Key West
Tue 11/17
6:05 pm-11:43 pm
1 stop5h 38m
$373
Quickest round-trip
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Sat 11/14
12:34 pm-5:56 pm
1 stop5h 22m
Key West
Thu 11/19
7:18 pm-12:03 am
1 stop4h 45m
$374
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Tue 9/15
12:45 pm-5:55 pm
1 stop5h 10m
Key West
Tue 9/22
12:45 pm-7:19 pm
1 stop6h 34m
$416
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Wed 11/11
2:35 pm-8:00 pm
1 stop5h 25m
Key West
Tue 11/17
6:05 pm-11:43 pm
1 stop5h 38m
$428
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Thu 9/17
2:33 pm-8:00 pm
1 stop5h 27m
Key West
Mon 9/21
6:19 pm-11:20 pm
1 stop5h 01m
$448
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Wed 12/2
12:34 pm-6:01 pm
1 stop5h 27m
Key West
Sat 12/5
1:52 pm-6:38 pm
1 stop4h 46m
$458
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Wed 11/11
2:35 pm-8:00 pm
1 stop5h 25m
Key West
Fri 11/13
7:25 am-10:40 am
1 stop27h 15m
$507
CharlestonKey West
CRW Charleston Yeager - EYW Key West
CRWEYW
Charleston Yeager
Sat 11/14
6:05 am-4:27 pm
2 stops10h 22m
Key West
Sat 11/21
7:16 pm-12:03 am
1 stop4h 47m
$543
Sorted by cheapest first
Compare providers for flights from Charleston to Key West
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Key West in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston, West Virginia-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston, West Virginia-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston, West Virginia-Key West flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston, West Virginia-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston, West Virginia-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Charleston with our price prediction graph.
CRW-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Key West
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated September 5, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Charleston to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Entertainment
7.8
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Crew
8.5
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Charleston to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to Key West
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Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Key West by cabin class
Find flights from Charleston to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 5, 2026.
Charleston and Key West flights
Browse other Charleston and Key West flight options. Last updated on September 5, 2026.
Other flights from Charleston
Browse through other flights departing from Charleston. Flights are based on user searches made on Cheapflights and were last updated on September 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Charleston to Key West
Discover the top 2 airlines that operate flights from Charleston to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$269 | Average$460 | FlexibilityNo cancel fee | On-time71% |