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$219+ Cheap flights from Jose Maria Cordova Intl (MDE) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
MDE — SCL
Apr 5 — Apr 121
Sun 4/5
Sun 4/12
1 adult, Economy
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Cheapflights Tip: The best prices from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez are usually found in May or April, booked 72 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Jose Maria Cordova Intl to Santiago

Cheapest flights from Jose Maria Cordova Intl to Santiago
Explore the most affordable flight options available from Jose Maria Cordova Intl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.

This JetSMART deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Mon 7/271:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/3$324
This JetSMART deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Fri 10/231:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/2$325
This JetSMART deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Sun 6/71:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/5$331
This FlightHub deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Mon 10/121:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/3$332
This JetSMART deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Sun 9/131:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/4$333
This JetSMART deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Sun 6/141:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/4$339
This JetSMART deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Fri 6/121:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/3$343
This JetSMART deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Sat 6/68:31 am
SCL
-
MDE
1 stop9h 09m
JetSMART
Deal found 3/6$344
This JetSMART deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:01 pm
MDE
-
SCL
Nonstop6h 10m
JetSMART
Mon 6/81:11 am
SCL
-
MDE
Nonstop6h 24m
JetSMART
Deal found 3/3$345

Find flight deals from Jose Maria Cordova Intl to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jose Maria Cordova Intl (MDE) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$324
(JetSMART)

One-way from

$219
(JetSMART)

Popular in

February

Cheapest in

May

Average price

$387

Good round-trip deal

$379 or less

Good one-way deal

$202 or less
Provider with most accurate pricing for Medellín Jose Maria Cordova Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medellín Jose Maria Cordova Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jose Maria Cordova Intl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Medellín Jose Maria Cordova Intl Airport to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 7/16

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Mon 7/27

1:11 am-6:35 am

Nonstop6h 24m

$324

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 8/20

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Sun 8/30

1:11 am-6:35 am

Nonstop6h 24m

$325

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 6/1

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Thu 6/4

1:11 am-6:35 am

Nonstop6h 24m

$334

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 6/15

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Sun 6/21

1:11 am-6:35 am

Nonstop6h 24m

$356

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Tue 5/5

5:25 pm-3:56 am

1 stop9h 31m

Santiago Arturo Merino Benitez

Sun 5/10

1:11 am-6:35 am

Nonstop6h 24m

$367

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 6/22

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Sun 6/28

1:11 am-6:35 am

Nonstop6h 24m

$367

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Sun 5/31

5:01 pm-12:11 am

Nonstop6h 10m

Santiago Arturo Merino Benitez

Tue 6/9

4:41 am-4:40 pm

1 stop12h 59m

$372

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 6/11

5:25 pm-4:11 am

1 stop9h 46m

Santiago Arturo Merino Benitez

Sat 6/13

4:56 am-4:40 pm

1 stop12h 44m

$381

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Thu 5/7

5:25 pm-4:11 am

1 stop9h 46m

Santiago Arturo Merino Benitez

Tue 5/12

4:46 am-4:40 pm

1 stop12h 54m

$383

MedellínSantiago

MDE - SCL

MDESCL

Medellín Jose Maria Cordova Intl

Mon 6/1

5:25 pm-3:56 am

1 stop9h 31m

Santiago Arturo Merino Benitez

Sun 6/14

1:11 am-6:35 am

Nonstop6h 24m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/2

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Jose Maria Cordova Intl to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jose Maria Cordova Intl to Santiago in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
Kiwi.comPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OneTravelPrice Accuracy3 starsTrust Score*3 stars
CheapOairPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medellín Jose Maria Cordova Intl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medellín Jose Maria Cordova Intl Airport-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medellín Jose Maria Cordova Intl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medellín Jose Maria Cordova Intl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jose Maria Cordova Intl to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jose Maria Cordova Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medellín Jose Maria Cordova Intl Airport to Santiago

How far ahead should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Jose Maria Cordova Intl to Santiago. Price data was last updated on February 27, 2026.

Booking 66 days in advance of your planned departure date is, on average, the best time to get cheap flights from Medellín Jose Maria Cordova Intl Airport to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

Currently, June is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $176). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in July is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDE to SCL?

Find hourly flight availability from Jose Maria Cordova Intl to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 6, 2026.

When flying from Medellín Jose Maria Cordova Intl Airport to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Medellín Jose Maria Cordova Intl Airport to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 6, 2026.
Get a feel of what it's like to fly with Copa Airlines, LATAM Airlines, and JetSMART from Medellín Jose Maria Cordova Intl Airport to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,561 reviews
Copa Airlines
7.5
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
LATAM Airlines
7.4
Good
1,917 reviews
Copa Airlines
7.5
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
JetSMART
6.7
Okay
276 reviews
Copa Airlines
7.5
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Avianca
6.5
Okay
2,496 reviews
Copa Airlines
7.5
Good
1,561 reviews

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Food

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Jose Maria Cordova Intl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago from Medellín Jose Maria Cordova Intl?

    Santiago Arturo Merino Benitez (SCL) is the airport you will fly into if you book a flight from Medellín Jose Maria Cordova Intl to Santiago. You should not have trouble finding flights to Arturo Merino Benitez from Medellín Jose Maria Cordova Intl; the airport handles an average of 0 inbound flights from Medellín Jose Maria Cordova Intl per day. You should also have plenty of airline options to choose from since 4 airlines have flights to the Santiago airport from Medellín Jose Maria Cordova Intl. It is only a 8.4 mi journey from Arturo Merino Benitez (SCL) to Santiago’s city center.

  • How long is the flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    For as low as $367, JetSMART can have you in Santiago from Medellín Jose Maria Cordova Intl Airport in 9h 31m. Medellín Jose Maria Cordova Intl Airport and Santiago are separated by a distance of 2748 mi.

  • What are the cheapest airlines flying from Medellín Jose Maria Cordova Intl Airport to Santiago round-trip?

    Currently priced at $156, JetSMART will fly you from Medellín Jose Maria Cordova Intl Airport to Santiago and back. In addition to JetSMART, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Copa Airlines and Avianca - these airlines can fly you to your destination from $240 and $310, respectively. These flights start at 61% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Medellín Jose Maria Cordova Intl Airport to Santiago one-way?

    For one-way options, check prices for JetSMART. According to our data, you can fly for as low as $129. Users have also found prices from $210 and $228 on Copa Airlines and LATAM Airlines, respectively.

  • What are the cheapest flights from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Looking at all options, your cheapest flight can be booked for $202. While the most popular route (Medellín Jose Maria Cordova Intl - Santiago Arturo Merino Benitez) can be booked for $357 on average, our data indicates $440 when flying from Medellín Jose Maria Cordova Intl Airport to Santiago.

  • Can I find deals for flights from Jose Maria Cordova Intl to Santiago that include hotel bookings?

    Yes. In addition to deals on Jose Maria Cordova Intl to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jose Maria Cordova Intl to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jose Maria Cordova Intl to Santiago.

  • Can I find deals for business class flights from Jose Maria Cordova Intl to Santiago?

    Yes. Cheapflights offers flight deals from Jose Maria Cordova Intl to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago (average of $176). Flying from Medellín Jose Maria Cordova Intl Airport to Santiago in July is currently the most expensive (average of $317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Top 4 airlines flying from Jose Maria Cordova Intl to Santiago

Discover the top 4 airlines that operate flights from Jose Maria Cordova Intl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetSMARTCheapest$156Average$380FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$240Average$441FlexibilityNo cancel feeOn-time70%
AviancaCheapest$310Average$439FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$319Average$444FlexibilityNo cancel feeOn-time81%

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