$371+ Cheap flights from George Bush Intcntl (IAH) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
IAH — SCL
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from George Bush Intcntl to Santiago
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Cheapest flights from George Bush Intcntl to SantiagoExplore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This eDestinos deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:24 pm
IAH
- SCL
2 stops41h 11m
Multiple Airlines
Sun 7/1911:00 pm
SCL
- IAH
3 stops47h 03m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$782
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Sun 6/78:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$814
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:37 pm
IAH
- SCL
1 stop22h 08m
Multiple Airlines
Tue 8/113:35 am
SCL
- IAH
2 stops29h 19m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$825
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:37 pm
IAH
- SCL
1 stop22h 08m
Multiple Airlines
Tue 8/115:00 am
SCL
- IAH
2 stops27h 54m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$837
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:37 pm
IAH
- SCL
2 stops28h 58m
Multiple Airlines
Sat 8/2211:00 pm
SCL
- IAH
1 stop13h 34m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$869
Best flights from George Bush Intcntl to SantiagoDiscover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Wed 6/248:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$879
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:12 pm
IAH
- SCL
1 stop11h 48m
American Airlines
Sun 7/199:00 pm
SCL
- IAH
1 stop12h 50m
American Airlines
Deal found 5/11![American Airlines logo]()
$1,128
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:50 am
IAH
- SCL
1 stop16h 50m
Delta
Wed 11/1811:10 pm
SCL
- IAH
1 stop20h 25m
Delta
Deal found 5/6![Delta logo]()
$1,135
This Avianca deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:45 pm
IAH
- SCL
2 stops19h 30m
Avianca
Wed 8/193:20 pm
SCL
- IAH
2 stops21h 45m
Avianca
Deal found 5/10![Avianca logo]()
$1,146
This Avianca deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:45 pm
IAH
- SCL
2 stops19h 30m
Avianca
Wed 6/312:30 am
SCL
- IAH
2 stops16h 40m
Avianca
Deal found 5/7![Avianca logo]()
$1,146
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:15 am
IAH
- SCL
1 stop22h 35m
American Airlines
Sun 10/49:30 pm
SCL
- IAH
1 stop14h 49m
American Airlines
Deal found 5/10![American Airlines logo]()
$1,168
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:09 pm
IAH
- SCL
1 stop18h 06m
Delta
Sun 7/198:40 pm
SCL
- IAH
1 stop22h 02m
Delta
Deal found 5/6![Delta logo]()
$1,175
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:38 pm
IAH
- SCL
1 stop15h 37m
Delta
Tue 8/48:40 pm
SCL
- IAH
1 stop20h 17m
Delta
Deal found 5/10![Delta logo]()
$1,185
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:52 pm
IAH
- SCL
1 stop13h 23m
Delta
Tue 9/87:45 pm
SCL
- IAH
2 stops18h 22m
Delta
Deal found 5/9![Delta logo]()
$1,185
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:52 pm
IAH
- SCL
1 stop13h 23m
Delta
Thu 9/38:40 pm
SCL
- IAH
1 stop16h 27m
Delta
Deal found 5/9![Delta logo]()
$1,185
Last-minute flights from George Bush Intcntl to SantiagoDiscover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated May 11, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Sun 6/78:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$814
This Mytrip deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Tue 6/93:35 am
SCL
- IAH
3 stops31h 39m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$903
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Wed 6/248:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$912
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Wed 6/248:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$879
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Tue 7/73:35 am
SCL
- IAH
3 stops31h 40m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$917
This Mytrip deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:55 pm
IAH
- SCL
3 stops30h 00m
Multiple Airlines
Thu 6/256:00 pm
SCL
- IAH
2 stops26h 25m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$926
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:24 pm
IAH
- SCL
2 stops41h 11m
Multiple Airlines
Mon 7/138:30 am
SCL
- IAH
2 stops24h 24m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$937
One-way flights from George Bush Intcntl to SantiagoSearch for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:44 pm
IAH
- SCL
3 stops30h 11m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:37 pm
IAH
- SCL
2 stops31h 58m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:37 pm
IAH
- SCL
2 stops30h 18m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:12 pm
IAH
- SCL
3 stops53h 48m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:05 pm
IAH
- SCL
3 stops51h 30m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$426
Find flight deals from George Bush Intcntl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from George Bush Intcntl (IAH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $782 (eDestinos) |
One-way from | $371 (Kiwi.com) |
Popular in | April |
Cheapest in | May |
Average price | $804 |
Cheapflights Fare Finder
Customize your flight search to find flights from George Bush Intcntl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 6/10
8:55 pm-2:35 am
3 stops28h 40m
Santiago Arturo Merino Benitez
Wed 6/24
8:20 pm-7:25 pm
2 stops24h 05m
$879
Quickest round-trip
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 7/8
6:12 pm-7:00 am
1 stop11h 48m
Santiago Arturo Merino Benitez
Sun 7/19
9:00 pm-8:50 am
1 stop12h 50m
$1,128
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 11/4
11:50 am-7:40 am
1 stop16h 50m
Santiago Arturo Merino Benitez
Wed 11/18
11:10 pm-4:35 pm
1 stop20h 25m
$1,135
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Mon 8/17
5:45 pm-2:15 pm
2 stops19h 30m
Santiago Arturo Merino Benitez
Wed 8/19
3:20 pm-12:05 pm
2 stops21h 45m
$1,146
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Sun 5/31
5:45 pm-2:15 pm
2 stops19h 30m
Santiago Arturo Merino Benitez
Wed 6/3
12:30 am-4:10 pm
2 stops16h 40m
$1,146
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Fri 8/21
7:15 am-6:50 am
1 stop22h 35m
Santiago Arturo Merino Benitez
Sun 10/4
9:30 pm-10:19 am
1 stop14h 49m
$1,168
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 7/8
12:09 pm-7:15 am
1 stop18h 06m
Santiago Arturo Merino Benitez
Sun 7/19
8:40 pm-5:42 pm
1 stop22h 02m
$1,175
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Tue 7/28
2:38 pm-7:15 am
1 stop15h 37m
Santiago Arturo Merino Benitez
Tue 8/4
8:40 pm-3:57 pm
1 stop20h 17m
$1,185
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 8/19
4:52 pm-7:15 am
1 stop13h 23m
Santiago Arturo Merino Benitez
Tue 9/8
7:45 pm-12:07 pm
2 stops18h 22m
$1,185
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Mon 8/24
4:52 pm-7:15 am
1 stop13h 23m
Santiago Arturo Merino Benitez
Thu 9/3
8:40 pm-12:07 pm
1 stop16h 27m
$1,185
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from George Bush Intcntl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from George Bush Intcntl to Santiago in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Houston George Bush Intcntl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Houston George Bush Intcntl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Houston George Bush Intcntl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from George Bush Intcntl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from George Bush Intcntl with our price prediction graph.
IAH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston George Bush Intcntl Airport to Santiago
What is the cheapest month to book a flight from Houston George Bush Intcntl Airport to Santiago?
Currently, May is the cheapest month in which you can book a flight from Houston George Bush Intcntl Airport to Santiago (average of $804). Flying from Houston George Bush Intcntl Airport to Santiago in April is currently the most expensive (average of $1,645). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston George Bush Intcntl Airport to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 11, 2026.
Peruse reviews from past customers who have flown with LATAM Airlines,United Airlines, andAmerican Airlines from Houston George Bush Intcntl Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.0
Boarding
7.5
Crew
8.0
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.0
Boarding
7.5
Crew
8.0
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.0
Boarding
7.5
Crew
8.0
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.0
Boarding
7.5
Crew
8.0
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from George Bush Intcntl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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George Bush Intcntl and Santiago flights
Browse other George Bush Intcntl and Santiago flight options. Last updated on May 11, 2026.
Other flights from George Bush Intcntl
Browse through other flights departing from George Bush Intcntl. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
Popular flight searches
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Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
Top 3 airlines flying from George Bush Intcntl to Santiago
Discover the top 3 airlines that operate flights from George Bush Intcntl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$949 | Average$1,169 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$963 | Average$1,193 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,050 | Average$1,645 | FlexibilityNo cancel fee | On-time71% |