$290+ Cheap flights from George Bush Intcntl (IAH) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
IAH — SCL
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from George Bush Intcntl to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from George Bush Intcntl to Santiago
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Best
Last-minute
One-way
Cheapest flights from George Bush Intcntl to SantiagoExplore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This SmartFares deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Tue 12/89:55 pm -
1 stop38h 12m
Deal found 11/9![Air Canada logo]()
$753
This Air Canada deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:50 am -
2 stops21h 25m
Sun 12/138:25 am -
2 stops29h 28m
Deal found 11/8![Air Canada logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:32 pm -
1 stop21h 43m
Thu 1/1410:12 pm -
2 stops36h 57m
Deal found 11/10![Multiple Airlines logo]()
$853
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:39 pm -
2 stops29h 04m
Thu 12/249:35 am -
1 stop25h 55m
Deal found 11/8![Multiple Airlines logo]()
$869
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:32 am -
2 stops33h 03m
Thu 12/108:35 am -
2 stops28h 27m
Deal found 11/5![Multiple Airlines logo]()
$872
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Tue 12/84:15 pm -
3 stops28h 14m
Deal found 11/9![Multiple Airlines logo]()
$874
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:50 pm -
3 stops31h 48m
Sat 6/196:00 pm -
2 stops26h 10m
Deal found 11/5![Multiple Airlines logo]()
$880
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:50 am -
1 stop16h 00m
Tue 12/158:25 am -
2 stops29h 28m
Deal found 11/5![Air Canada logo]()
$891
This Priceline deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Thu 12/109:55 pm -
1 stop22h 23m
Deal found 11/5![Air Canada logo]()
$897
Best flights from George Bush Intcntl to SantiagoDiscover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/285:10 am -
2 stops23h 20m
Wed 1/138:25 pm -
2 stops18h 03m
Deal found 11/7![Delta logo]()
$1,339
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/188:30 pm -
Nonstop9h 20m
Thu 3/259:45 pm -
Nonstop9h 40m
Deal found 11/6![United Airlines logo]()
$1,466
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:30 pm -
Nonstop9h 20m
Tue 12/1510:45 pm -
Nonstop9h 40m
Deal found 11/10![United Airlines logo]()
$1,591
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:40 pm -
1 stop14h 00m
Thu 12/3112:30 am -
2 stops22h 47m
Deal found 11/5![Delta logo]()
$1,746
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:30 pm -
Nonstop9h 20m
Thu 12/3110:45 pm -
Nonstop9h 40m
Deal found 11/6![United Airlines logo]()
$1,591
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:46 pm -
1 stop32h 54m
Thu 12/3112:30 am -
2 stops22h 47m
Deal found 11/8![Delta logo]()
$1,799
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:00 am -
1 stop21h 40m
Thu 12/3111:00 pm -
1 stop17h 32m
Deal found 11/8![Delta logo]()
$1,871
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:36 am -
1 stop17h 04m
Mon 1/411:00 pm -
1 stop15h 28m
Deal found 11/5![Delta logo]()
$2,216
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/58:30 pm -
Nonstop9h 20m
Wed 3/179:45 pm -
Nonstop9h 40m
Deal found 11/8![United Airlines logo]()
$2,451
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:30 pm -
Nonstop9h 20m
Sun 11/2910:45 pm -
Nonstop9h 40m
Deal found 11/5![United Airlines logo]()
$2,521
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:30 pm -
Nonstop9h 20m
Mon 11/3010:45 pm -
Nonstop9h 40m
Deal found 11/7![United Airlines logo]()
$2,556
Last-minute flights from George Bush Intcntl to SantiagoDiscover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated November 10, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:50 am -
1 stop16h 00m
Tue 12/158:25 am -
2 stops29h 28m
Deal found 11/5![Air Canada logo]()
$891
This SmartFares deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Tue 12/89:55 pm -
1 stop38h 12m
Deal found 11/9![Air Canada logo]()
$753
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:32 am -
2 stops33h 03m
Thu 12/108:35 am -
2 stops28h 27m
Deal found 11/5![Multiple Airlines logo]()
$872
This Mytrip deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Tue 12/84:15 pm -
3 stops28h 14m
Deal found 11/9![Multiple Airlines logo]()
$874
This Priceline deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:50 am -
1 stop16h 00m
Thu 12/109:55 pm -
1 stop22h 23m
Deal found 11/5![Air Canada logo]()
$897
This Air Canada deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/611:50 am -
2 stops21h 25m
Sun 12/138:25 am -
2 stops29h 28m
Deal found 11/8![Air Canada logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:39 pm -
2 stops29h 04m
Thu 12/249:35 am -
1 stop25h 55m
Deal found 11/8![Multiple Airlines logo]()
$869
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/318:32 pm -
1 stop21h 43m
Thu 1/1410:12 pm -
2 stops36h 57m
Deal found 11/10![Multiple Airlines logo]()
$853
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:50 pm -
3 stops31h 48m
Sat 6/196:00 pm -
2 stops26h 10m
Deal found 11/5![Multiple Airlines logo]()
$880
One-way flights from George Bush Intcntl to SantiagoSearch for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1012:03 pm -
2 stops31h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/263:52 pm -
2 stops35h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/317:50 pm -
3 stops31h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$347
This Trip.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:39 am -
2 stops19h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:39 pm -
2 stops28h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:24 pm -
3 stops56h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$392
Find flight deals from George Bush Intcntl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from George Bush Intcntl (IAH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $753 (SmartFares) |
One-way from | $290 (Kiwi.com) |
Popular in | October |
Cheapest in | March |
Average price | $1,365 |
Good round-trip deal | $1,280 or less |
Good one-way deal | $932 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from George Bush Intcntl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/31
7:50 pm-6:38 am
3 stops31h 48m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$347
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Fri 12/4
12:06 pm-12:40 pm
3 stops45h 34m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 11/16
2:32 pm-3:35 am
3 stops34h 03m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$444
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Tue 11/24
1:44 pm-9:15 pm
2 stops28h 31m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$500
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Wed 1/13
12:00 pm-12:15 pm
1 stop21h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$524
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 4/5
10:18 am-9:36 pm
3 stops34h 18m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$556
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Fri 12/4
11:55 am-12:15 pm
1 stop21h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$557
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/10
7:01 pm-9:15 pm
1 stop23h 14m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$587
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 12/21
4:45 pm-3:10 pm
2 stops19h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$1,082
Quickest round-trip
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/31
8:30 pm-8:50 am
Nonstop9h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$1,264
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from George Bush Intcntl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from George Bush Intcntl to Santiago in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Houston George Bush Intcntl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Houston George Bush Intcntl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Houston George Bush Intcntl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from George Bush Intcntl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from George Bush Intcntl with our price prediction graph.
IAH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston George Bush Intcntl Airport to Santiago
Prices
More
What is the cheapest month to book a flight from Houston George Bush Intcntl Airport to Santiago?
Currently, March is the cheapest month in which you can book a flight from Houston George Bush Intcntl Airport to Santiago (average of $1,149). Flying from Houston George Bush Intcntl Airport to Santiago in October is currently the most expensive (average of $3,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IAH to SCL?
Find hourly flight availability from George Bush Intcntl to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2026.
When flying from Houston George Bush Intcntl Airport to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from Houston George Bush Intcntl Airport to Santiago?
Share of 1-stop round-trip flights from Houston George Bush Intcntl Airport to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Miami (MIA) – chosen by Cheapflights users on 75% of 1-stop itineraries from Houston George Bush Intcntl Airport to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Houston George Bush Intcntl Airport to Santiago?
Average round-trip fare for 1-stop flights from Houston George Bush Intcntl Airport to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Miami (MIA) is the most affordable 1-stop option, with an average round-trip price of $1,175.
What’s the fastest layover option from Houston George Bush Intcntl Airport to Santiago?
Shortest average travel time for 1-stop one-way flights from Houston George Bush Intcntl Airport to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 11h 36m.
Which airport typically offers the quickest layover for flights from Houston George Bush Intcntl Airport to Santiago?
Average layover duration for 1-stop one-way flights from Houston George Bush Intcntl Airport to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 10, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Houston George Bush Intcntl Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Food
6.7
Crew
8.1
Boarding
7.7
Overall
7.3
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Entertainment
7.1
Food
6.7
Crew
8.1
Boarding
7.7
Overall
7.3
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Entertainment
7.1
Food
6.7
Crew
8.1
Boarding
7.7
Overall
7.3
Comfort
7.3
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
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Top 2 airlines flying from George Bush Intcntl to Santiago
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$1,010 | Average$1,320 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,086 | Average$1,405 | FlexibilityNo cancel fee | On-time71% |