$313+ Cheap flights from George Bush Intcntl (IAH) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
IAH — SCL
Jun 15 — Jun 221
Round-trip
1 adult, Economy
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Cheapest flights from George Bush Intcntl to SantiagoExplore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 16, 2026.
Explore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:44 pm
IAH
- SCL
2 stops46h 39m
Multiple Airlines
Wed 6/1710:30 am
SCL
- IAH
1 stop22h 32m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$849
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:24 pm
IAH
- SCL
2 stops30h 36m
Multiple Airlines
Thu 6/258:30 am
SCL
- IAH
2 stops24h 32m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$871
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:44 pm
IAH
- SCL
2 stops30h 16m
Multiple Airlines
Wed 6/311:00 pm
SCL
- IAH
1 stop13h 42m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$874
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:37 pm
IAH
- SCL
1 stop22h 08m
Multiple Airlines
Mon 8/178:20 pm
SCL
- IAH
2 stops40h 14m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$886
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:28 pm
IAH
- SCL
2 stops32h 35m
Multiple Airlines
Tue 6/1611:00 pm
SCL
- IAH
1 stop34h 02m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$894
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:33 pm
IAH
- SCL
2 stops30h 27m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$898
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:44 pm
IAH
- SCL
2 stops25h 59m
Multiple Airlines
Sun 6/78:30 am
SCL
- IAH
2 stops28h 12m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$900
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Mon 6/294:50 pm
SCL
- IAH
2 stops27h 35m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$903
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:28 pm
IAH
- SCL
2 stops26h 15m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$904
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:44 pm
IAH
- SCL
2 stops46h 39m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$906
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:57 pm
IAH
- SCL
2 stops36h 38m
Multiple Airlines
Wed 6/1010:30 am
SCL
- IAH
1 stop22h 32m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$912
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:24 pm
IAH
- SCL
2 stops46h 59m
Multiple Airlines
Sun 7/511:00 pm
SCL
- IAH
1 stop33h 54m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$914
Best flights from George Bush Intcntl to SantiagoDiscover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 16, 2026.
Discover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:28 pm
IAH
- SCL
2 stops32h 35m
Multiple Airlines
Tue 6/1611:00 pm
SCL
- IAH
1 stop34h 02m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$894
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:08 pm
IAH
- SCL
2 stops16h 42m
American Airlines
Sat 10/109:30 pm
SCL
- IAH
1 stop14h 49m
American Airlines
Deal found 5/12![American Airlines logo]()
$1,090
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:52 pm
IAH
- SCL
1 stop13h 23m
Delta
Mon 8/178:40 pm
SCL
- IAH
1 stop22h 00m
Delta
Deal found 5/15![Delta logo]()
$1,135
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:24 pm
IAH
- SCL
2 stops29h 26m
Multiple Airlines
Wed 7/110:30 am
SCL
- IAH
1 stop22h 32m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$938
This Mytrip deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:05 pm
IAH
- SCL
3 stops34h 15m
Multiple Airlines
Mon 8/173:20 pm
SCL
- IAH
3 stops29h 05m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$954
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/812:09 pm
IAH
- SCL
1 stop18h 06m
Delta
Sun 7/198:40 pm
SCL
- IAH
1 stop22h 02m
Delta
Deal found 5/12![Delta logo]()
$1,175
This Mytrip deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:05 pm
IAH
- SCL
3 stops34h 15m
Multiple Airlines
Fri 10/91:30 am
SCL
- IAH
2 stops16h 40m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$986
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:05 pm
IAH
- SCL
3 stops25h 10m
Multiple Airlines
Tue 10/274:25 pm
SCL
- IAH
2 stops21h 40m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$986
This Mytrip deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:55 pm
IAH
- SCL
2 stops25h 25m
Multiple Airlines
Mon 6/13:20 pm
SCL
- IAH
3 stops21h 45m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$1,087
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:52 am
IAH
- SCL
1 stop32h 18m
Multiple Airlines
Fri 6/1912:55 am
SCL
- IAH
3 stops32h 07m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$1,177
Last-minute flights from George Bush Intcntl to SantiagoDiscover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated May 16, 2026 and is based on user searches.
Discover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated May 16, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:44 pm
IAH
- SCL
2 stops30h 16m
Multiple Airlines
Wed 6/311:00 pm
SCL
- IAH
1 stop13h 42m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$874
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:44 pm
IAH
- SCL
2 stops46h 39m
Multiple Airlines
Wed 6/1710:30 am
SCL
- IAH
1 stop22h 32m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$849
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:44 pm
IAH
- SCL
2 stops25h 59m
Multiple Airlines
Sun 6/78:30 am
SCL
- IAH
2 stops28h 12m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$900
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:57 pm
IAH
- SCL
2 stops36h 38m
Multiple Airlines
Wed 6/1010:30 am
SCL
- IAH
1 stop22h 32m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$912
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:28 pm
IAH
- SCL
2 stops26h 15m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$904
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:44 pm
IAH
- SCL
2 stops46h 39m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$906
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:33 pm
IAH
- SCL
2 stops30h 27m
Multiple Airlines
Sun 8/212:40 am
SCL
- IAH
1 stop32h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$898
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:28 pm
IAH
- SCL
2 stops32h 35m
Multiple Airlines
Tue 6/1611:00 pm
SCL
- IAH
1 stop34h 02m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$894
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Mon 6/294:50 pm
SCL
- IAH
2 stops27h 35m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$903
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/207:24 pm
IAH
- SCL
2 stops30h 36m
Multiple Airlines
Thu 6/258:30 am
SCL
- IAH
2 stops24h 32m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$871
This Mytrip deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:55 pm
IAH
- SCL
3 stops28h 40m
Multiple Airlines
Thu 6/258:20 pm
SCL
- IAH
2 stops24h 05m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$920
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:24 pm
IAH
- SCL
2 stops46h 59m
Multiple Airlines
Sun 7/511:00 pm
SCL
- IAH
1 stop33h 54m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$914
One-way flights from George Bush Intcntl to SantiagoSearch for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated May 16, 2026.
Search for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated May 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:53 pm
IAH
- SCL
2 stops40h 42m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:12 am
IAH
- SCL
3 stops55h 11m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:55 pm
IAH
- SCL
3 stops29h 05m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:51 am
IAH
- SCL
3 stops38h 09m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:27 pm
IAH
- SCL
3 stops37h 33m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:53 pm
IAH
- SCL
2 stops32h 42m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:44 pm
IAH
- SCL
2 stops46h 39m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:44 pm
IAH
- SCL
3 stops40h 01m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$369
Find flight deals from George Bush Intcntl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from George Bush Intcntl (IAH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $849 (Kiwi.com) |
One-way from | $313 (Kiwi.com) |
Popular in | April |
Cheapest in | May |
Average price | $804 |
Cheapflights Fare Finder
Customize your flight search to find flights from George Bush Intcntl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Sun 6/7
7:28 pm-5:03 am
2 stops32h 35m
Santiago Arturo Merino Benitez
Tue 6/16
11:00 pm-8:02 am
1 stop34h 02m
$894
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Thu 6/25
7:24 pm-1:50 am
2 stops29h 26m
Santiago Arturo Merino Benitez
Wed 7/1
10:30 am-8:02 am
1 stop22h 32m
$938
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Tue 8/11
12:05 pm-11:20 pm
3 stops34h 15m
Santiago Arturo Merino Benitez
Mon 8/17
3:20 pm-7:25 pm
3 stops29h 05m
$954
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Sun 10/4
12:05 pm-12:20 am
3 stops34h 15m
Santiago Arturo Merino Benitez
Fri 10/9
1:30 am-4:10 pm
2 stops16h 40m
$986
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Tue 10/20
12:05 pm-3:15 pm
3 stops25h 10m
Santiago Arturo Merino Benitez
Tue 10/27
4:25 pm-12:05 pm
2 stops21h 40m
$986
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Thu 5/28
8:55 pm-11:20 pm
2 stops25h 25m
Santiago Arturo Merino Benitez
Mon 6/1
3:20 pm-12:05 pm
3 stops21h 45m
$1,087
Quickest round-trip
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Sun 10/4
2:08 pm-8:50 am
2 stops16h 42m
Santiago Arturo Merino Benitez
Sat 10/10
9:30 pm-10:19 am
1 stop14h 49m
$1,090
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 8/5
4:52 pm-7:15 am
1 stop13h 23m
Santiago Arturo Merino Benitez
Mon 8/17
8:40 pm-5:40 pm
1 stop22h 00m
$1,135
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Wed 7/8
12:09 pm-7:15 am
1 stop18h 06m
Santiago Arturo Merino Benitez
Sun 7/19
8:40 pm-5:42 pm
1 stop22h 02m
$1,175
HoustonSantiago
IAH - SCL
IAHSCL
Houston George Bush Intcntl
Sat 6/13
11:52 am-9:10 pm
1 stop32h 18m
Santiago Arturo Merino Benitez
Fri 6/19
12:55 am-8:02 am
3 stops32h 07m
$1,177
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from George Bush Intcntl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from George Bush Intcntl to Santiago in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Houston George Bush Intcntl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Houston George Bush Intcntl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Houston George Bush Intcntl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from George Bush Intcntl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from George Bush Intcntl with our price prediction graph.
IAH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston George Bush Intcntl Airport to Santiago
What is the cheapest month to book a flight from Houston George Bush Intcntl Airport to Santiago?
Currently, May is the cheapest month in which you can book a flight from Houston George Bush Intcntl Airport to Santiago (average of $804). Flying from Houston George Bush Intcntl Airport to Santiago in April is currently the most expensive (average of $1,645). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston George Bush Intcntl Airport to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 16, 2026.
Peruse reviews from past customers who have flown with LATAM Airlines,United Airlines, andAmerican Airlines from Houston George Bush Intcntl Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Comfort
7.3
Entertainment
7.0
Boarding
7.5
Crew
8.0
Overall
7.4
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Food
6.7
Comfort
7.3
Entertainment
7.0
Boarding
7.5
Crew
8.0
Overall
7.4
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Food
6.7
Comfort
7.3
Entertainment
7.0
Boarding
7.5
Crew
8.0
Overall
7.4
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Food
6.7
Comfort
7.3
Entertainment
7.0
Boarding
7.5
Crew
8.0
Overall
7.4
Reviews
1 / 20
6.0
GoodJuan,Apr 2026
BOG - CLO
Related info for your journey
Find useful and relevant information for your journey from George Bush Intcntl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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George Bush Intcntl and Santiago flights
Browse other George Bush Intcntl and Santiago flight options. Last updated on May 16, 2026.
Other flights from George Bush Intcntl
Browse through other flights departing from George Bush Intcntl. Flights are based on user searches made on Cheapflights and were last updated on May 16, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 16, 2026.
Top 3 airlines flying from George Bush Intcntl to Santiago
Discover the top 3 airlines that operate flights from George Bush Intcntl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$949 | Average$1,169 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$963 | Average$1,193 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,050 | Average$1,645 | FlexibilityNo cancel fee | On-time71% |