$303+ Cheap flights from George Bush Intcntl (IAH) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
IAH — SCL
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from George Bush Intcntl to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from George Bush Intcntl to Santiago
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Cheapest flights from George Bush Intcntl to SantiagoExplore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from George Bush Intcntl to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Trip.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:32 pm -
2 stops37h 06m
Thu 11/269:55 pm -
1 stop22h 13m
Deal found 9/22![Multiple Airlines logo]()
$744
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:35 pm -
2 stops28h 00m
Fri 11/2011:25 pm -
1 stop35h 54m
Deal found 9/18![Multiple Airlines logo]()
$754
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:32 pm -
2 stops37h 06m
Thu 11/128:35 am -
2 stops32h 12m
Deal found 9/22![Multiple Airlines logo]()
$755
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:21 pm -
2 stops32h 17m
Fri 11/2011:25 pm -
1 stop35h 54m
Deal found 9/18![Multiple Airlines logo]()
$762
This Mytrip deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:14 pm -
3 stops30h 24m
Tue 11/104:15 pm -
3 stops25h 35m
Deal found 9/20![Multiple Airlines logo]()
$770
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:21 pm -
2 stops32h 17m
Tue 11/179:35 am -
1 stop25h 44m
Deal found 9/18![Multiple Airlines logo]()
$771
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:35 pm -
2 stops28h 03m
Fri 11/2011:25 pm -
1 stop35h 54m
Deal found 9/18![Multiple Airlines logo]()
$775
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:35 pm -
2 stops28h 03m
Tue 11/179:35 am -
1 stop25h 44m
Deal found 9/18![Multiple Airlines logo]()
$784
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:21 pm -
3 stops31h 17m
Tue 11/249:55 pm -
2 stops26h 44m
Deal found 9/18![Multiple Airlines logo]()
$795
Best flights from George Bush Intcntl to SantiagoDiscover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from George Bush Intcntl to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:30 pm -
Nonstop9h 20m
Tue 12/1510:45 pm -
Nonstop9h 40m
Deal found 9/18![United Airlines logo]()
$1,135
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:05 am -
2 stops20h 25m
Mon 11/3012:48 am -
2 stops19h 41m
Deal found 9/20![Delta logo]()
$1,195
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:05 am -
2 stops20h 25m
Mon 11/3011:10 pm -
1 stop25h 56m
Deal found 9/21![Delta logo]()
$1,201
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:50 pm -
Nonstop9h 00m
Thu 11/1210:45 pm -
Nonstop9h 40m
Deal found 9/21![United Airlines logo]()
$1,266
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/201:15 pm -
2 stops22h 45m
Sat 3/611:55 pm -
1 stop17h 55m
Deal found 9/20![Delta logo]()
$1,235
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/218:30 pm -
Nonstop9h 20m
Sun 1/3110:45 pm -
Nonstop9h 40m
Deal found 9/20![United Airlines logo]()
$1,306
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
2 stops21h 30m
Sat 11/288:13 am -
2 stops18h 46m
Deal found 9/22![Delta logo]()
$1,285
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:30 pm -
Nonstop9h 20m
Mon 11/3010:45 pm -
Nonstop9h 40m
Deal found 9/21![United Airlines logo]()
$1,306
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:00 am -
2 stops21h 30m
Sun 11/2911:10 pm -
1 stop19h 12m
Deal found 9/18![Delta logo]()
$1,290
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:50 pm -
Nonstop9h 00m
Sat 11/2110:45 pm -
Nonstop9h 40m
Deal found 9/20![United Airlines logo]()
$1,346
Last-minute flights from George Bush Intcntl to SantiagoDiscover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from George Bush Intcntl to Santiago. Data last updated September 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:21 pm -
2 stops36h 39m
Tue 11/39:35 am -
1 stop25h 44m
Deal found 9/22![Multiple Airlines logo]()
$994
This Mytrip deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:12 pm -
3 stops28h 23m
Fri 10/305:00 am -
3 stops28h 23m
Deal found 9/23![Multiple Airlines logo]()
$818
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:14 am -
3 stops29h 01m
Tue 10/277:30 am -
3 stops34h 00m
Deal found 9/22![Multiple Airlines logo]()
$883
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:35 pm -
3 stops31h 10m
Thu 10/297:43 am -
3 stops32h 04m
Deal found 9/22![Multiple Airlines logo]()
$964
This Mytrip deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:31 am -
3 stops34h 05m
Tue 10/274:15 pm -
3 stops24h 35m
Deal found 9/20![Multiple Airlines logo]()
$857
This Mytrip deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:32 pm -
2 stops31h 23m
Tue 11/34:15 pm -
3 stops25h 35m
Deal found 9/23![Multiple Airlines logo]()
$941
One-way flights from George Bush Intcntl to SantiagoSearch for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from George Bush Intcntl to Santiago. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:35 pm -
2 stops29h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:35 pm -
2 stops49h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:21 pm -
3 stops29h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:00 pm -
2 stops30h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:35 pm -
2 stops28h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:39 pm -
3 stops30h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:00 pm -
2 stops30h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$351
Find flight deals from George Bush Intcntl to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from George Bush Intcntl (IAH) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $744 (Trip.com) |
One-way from | $303 (Kiwi.com) |
Popular in | May |
Cheapest in | February |
Average price | $1,799 |
Good round-trip deal | $1,170 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from George Bush Intcntl to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Houston George Bush Intcntl Airport to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Sat 10/24
6:35 pm-8:19 pm
2 stops47h 44m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$316
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Sun 10/4
8:25 pm-7:00 am
2 stops32h 35m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$411
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/10
6:24 pm-10:35 pm
3 stops49h 11m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$433
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Tue 9/29
9:04 pm-7:00 am
3 stops31h 56m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$463
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/24
9:15 am-10:35 pm
2 stops34h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$507
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Mon 10/12
8:35 pm-8:15 am
2 stops33h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$513
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Fri 2/5
10:35 am-9:15 pm
1 stop31h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$557
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Fri 12/18
9:15 am-5:03 am
3 stops40h 48m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$628
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Wed 10/14
12:00 pm-4:00 pm
2 stops26h 00m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$904
Quickest round-trip
HoustonSantiago
IAH Houston George Bush Intcntl - SCL Santiago Arturo Merino Benitez
IAHSCL
Houston George Bush Intcntl
Thu 12/10
8:30 pm-8:50 am
Nonstop9h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$1,064
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from George Bush Intcntl to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from George Bush Intcntl to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Houston George Bush Intcntl Airport-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Houston George Bush Intcntl Airport-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Houston George Bush Intcntl Airport-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Houston George Bush Intcntl Airport-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from George Bush Intcntl to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from George Bush Intcntl with our price prediction graph.
IAH-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Houston George Bush Intcntl Airport to Santiago
Prices
More
What is the cheapest month to book a flight from Houston George Bush Intcntl Airport to Santiago?
Currently, February is the cheapest month in which you can book a flight from Houston George Bush Intcntl Airport to Santiago (average of $989). Flying from Houston George Bush Intcntl Airport to Santiago in May is currently the most expensive (average of $2,231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Houston George Bush Intcntl Airport to Santiago?
Airfare is below average for this route at the moment.
Houston George Bush Intcntl Airport to Santiago flights typically cost between $1,460 and $1,604 in November.The cheapest round-trip price found within the last 5 days was $744 on Multiple Airlines (Nov 12-Nov 26).
What’s the top layover airport for flights from Houston George Bush Intcntl Airport to Santiago?
Share of 1-stop round-trip flights from Houston George Bush Intcntl Airport to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.
Miami (MIA) – chosen by Cheapflights users on 75% of 1-stop itineraries from Houston George Bush Intcntl Airport to Santiago on Cheapflights.
What’s the cheapest layover airport for flights from Houston George Bush Intcntl Airport to Santiago?
Average round-trip fare for 1-stop flights from Houston George Bush Intcntl Airport to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Miami (MIA) is the most affordable 1-stop option, with an average round-trip price of $1,175.
What’s the fastest layover option from Houston George Bush Intcntl Airport to Santiago?
Shortest average travel time for 1-stop one-way flights from Houston George Bush Intcntl Airport to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Panama City (PTY) have the shortest average one-way travel time for 1-stop routes: 11h 36m.
Which airport typically offers the quickest layover for flights from Houston George Bush Intcntl Airport to Santiago?
Average layover duration for 1-stop one-way flights from Houston George Bush Intcntl Airport to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Panama City (PTY) offer the fastest connection on this route, with an average layover time of 1h 05m.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 23, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Houston George Bush Intcntl Airport to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Boarding
7.7
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Boarding
7.7
Comfort
7.3
Overall
7.4
Food
6.7
Entertainment
7.1
Crew
8.1
Reviews
1 / 20
2.0
MediocreSebrena,Oct 2025
IAH - RSW
Related info for your journey
Find useful and relevant information for your journey from George Bush Intcntl to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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George Bush Intcntl and Santiago flights
Browse other George Bush Intcntl and Santiago flight options. Last updated on September 23, 2026.
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Browse through other flights departing from George Bush Intcntl. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 23, 2026.
Top 2 airlines flying from George Bush Intcntl to Santiago
Discover the top 2 airlines that operate flights from George Bush Intcntl to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$989 | Average$1,260 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,086 | Average$1,405 | FlexibilityNo cancel fee | On-time71% |