$199+ Cheap flights from Memphis to Des Moines (MEM - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Find cheap flights from Memphis to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Memphis to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Memphis to Des MoinesExplore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am -
1 stop7h 25m
Wed 9/162:40 pm -
1 stop7h 50m
Deal found 8/10![Southwest logo]()
$240
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 pm -
1 stop4h 37m
Wed 9/95:45 am -
1 stop6h 47m
Deal found 8/10![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
1 stop5h 50m
Tue 9/152:40 pm -
2 stops7h 10m
Deal found 8/11![Southwest logo]()
$252
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:20 pm -
1 stop6h 05m
Thu 9/36:33 am -
1 stop4h 40m
Deal found 8/11![American Airlines logo]()
$276
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:16 pm -
1 stop7h 32m
Mon 10/126:55 pm -
1 stop4h 21m
Deal found 8/7![United Airlines logo]()
$314
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:21 am -
2 stops7h 58m
Wed 9/96:41 am -
1 stop4h 26m
Deal found 8/10![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:20 pm -
1 stop6h 05m
Sun 9/66:34 am -
1 stop7h 44m
Deal found 8/11![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:45 am -
1 stop7h 14m
Sun 9/206:41 am -
1 stop4h 26m
Deal found 8/11![American Airlines logo]()
$326
Best flights from Memphis to Des MoinesDiscover carefully curated flight deals from Memphis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Memphis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am -
1 stop7h 25m
Wed 9/162:40 pm -
1 stop7h 50m
Deal found 8/10![Southwest logo]()
$240
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
1 stop4h 17m
Tue 9/155:45 am -
1 stop5h 02m
Deal found 8/11![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:30 am -
1 stop6h 41m
Mon 2/11:45 pm -
1 stop7h 29m
Deal found 8/10![United Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:56 am -
1 stop7h 52m
Sun 9/207:58 pm -
1 stop4h 25m
Deal found 8/7![American Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
1 stop5h 50m
Tue 9/152:40 pm -
2 stops7h 10m
Deal found 8/11![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 pm -
1 stop4h 37m
Wed 9/95:45 am -
1 stop6h 47m
Deal found 8/7![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:21 am -
2 stops7h 58m
Wed 9/96:41 am -
1 stop4h 26m
Deal found 8/11![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop7h 19m
Mon 11/231:27 pm -
1 stop7h 09m
Deal found 8/8![United Airlines logo]()
$357
Last-minute flights from Memphis to Des MoinesDiscover last-minute flight deals from Memphis to Des Moines. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Memphis to Des Moines. Data last updated August 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:20 pm -
1 stop6h 05m
Thu 9/36:33 am -
1 stop4h 40m
Deal found 8/11![American Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 pm -
1 stop4h 37m
Wed 9/95:45 am -
1 stop6h 47m
Deal found 8/10![Delta logo]()
$245
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:21 am -
2 stops7h 58m
Wed 9/96:41 am -
1 stop4h 26m
Deal found 8/10![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:20 pm -
1 stop6h 05m
Sun 9/66:34 am -
1 stop7h 44m
Deal found 8/11![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am -
1 stop5h 50m
Tue 9/152:40 pm -
2 stops7h 10m
Deal found 8/11![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:30 am -
1 stop7h 25m
Wed 9/162:40 pm -
1 stop7h 50m
Deal found 8/10![Southwest logo]()
$240
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:45 am -
1 stop7h 14m
Sun 9/206:41 am -
1 stop4h 26m
Deal found 8/11![American Airlines logo]()
$326
One-way flights from Memphis to Des MoinesSearch for one-way flight options from Memphis to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Memphis to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:15 am -
1 stop7h 01m
Deal found 8/9![United Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:44 pm -
1 stop6h 36m
Deal found 8/11![American Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:25 pm -
2 stops9h 30m
Deal found 8/11![Southwest logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:50 pm -
3 stops31h 18m
Deal found 8/9![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:50 pm -
2 stops22h 44m
Deal found 8/9![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:57 pm -
3 stops22h 06m
Deal found 8/10![Multiple Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:26 am -
1 stop5h 39m
Deal found 8/10![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:55 pm -
2 stops7h 15m
Deal found 8/10![Southwest logo]()
$329
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/254:33 pm -
3 stops24h 55m
Deal found 8/11![United Airlines logo]()
$530
Find flight deals from Memphis to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Southwest) |
One-way from | $199 (United Airlines) |
Popular in | April |
Cheapest in | September |
Average price | $391 |
Cheapflights Fare Finder
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Wed 9/9
6:30 am-1:55 pm
1 stop7h 25m
Des Moines
Wed 9/16
2:40 pm-10:30 pm
1 stop7h 50m
$240
Quickest round-trip
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Tue 9/8
6:00 am-10:17 am
1 stop4h 17m
Des Moines
Tue 9/15
5:45 am-10:47 am
1 stop5h 02m
$245
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Tue 9/8
6:00 am-11:50 am
1 stop5h 50m
Des Moines
Tue 9/15
2:40 pm-9:50 pm
2 stops7h 10m
$252
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Wed 9/2
6:00 pm-10:37 pm
1 stop4h 37m
Des Moines
Wed 9/9
5:45 am-12:32 pm
1 stop6h 47m
$299
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 1/28
7:30 am-2:11 pm
1 stop6h 41m
Des Moines
Mon 2/1
1:45 pm-9:14 pm
1 stop7h 29m
$303
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 9/17
11:56 am-7:48 pm
1 stop7h 52m
Des Moines
Sun 9/20
7:58 pm-12:23 am
1 stop4h 25m
$328
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Wed 9/2
11:21 am-7:19 pm
2 stops7h 58m
Des Moines
Wed 9/9
6:41 am-11:07 am
1 stop4h 26m
$330
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 11/19
7:00 am-2:19 pm
1 stop7h 19m
Des Moines
Mon 11/23
1:27 pm-8:36 pm
1 stop7h 09m
$357
Cheapest one-way
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 9/3
7:15 am-2:16 pm
1 stop7h 01m
$199
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Tue 8/25
12:25 pm-9:55 pm
2 stops9h 30m
$240
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Memphis to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Memphis to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Memphis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Memphis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Memphis-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Memphis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Memphis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Memphis to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
MEM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 12, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Memphis and Des Moines flights
Browse other Memphis and Des Moines flight options. Last updated on August 12, 2026.
Other flights from Memphis
Browse through other flights departing from Memphis. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Memphis to Des Moines
Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$185 | Average$456 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$201 | Average$452 | FlexibilityNo cancel fee | On-timeN/A |