$117+ Cheap flights from Memphis to Des Moines (MEM - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Memphis to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Memphis to Des Moines
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Cheapest flights from Memphis to Des MoinesExplore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:16 pm -
1 stop7h 32m
Mon 10/266:45 pm -
1 stop4h 59m
Deal found 9/18![United Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:36 pm -
1 stop6h 47m
Wed 10/211:27 pm -
1 stop7h 38m
Deal found 9/15![United Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:16 pm -
1 stop7h 32m
Sun 10/258:00 am -
1 stop6h 53m
Deal found 9/18![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:50 pm -
1 stop5h 08m
Wed 12/308:05 pm -
1 stop4h 36m
Deal found 9/18![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:04 am -
1 stop5h 30m
Mon 10/56:55 pm -
1 stop4h 21m
Deal found 9/16![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:40 pm -
1 stop5h 32m
Mon 10/54:12 pm -
1 stop6h 59m
Deal found 9/15![American Airlines logo]()
$392
Best flights from Memphis to Des MoinesDiscover carefully curated flight deals from Memphis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Memphis to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:16 pm -
1 stop7h 32m
Mon 10/266:45 pm -
1 stop4h 59m
Deal found 9/18![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:10 am -
1 stop7h 10m
Mon 10/54:30 pm -
2 stops7h 05m
Deal found 9/16![Southwest logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:16 am -
1 stop6h 15m
Sun 10/46:00 am -
1 stop6h 16m
Deal found 9/14![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:36 pm -
1 stop6h 47m
Wed 10/211:27 pm -
1 stop7h 38m
Deal found 9/16![United Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:04 am -
1 stop5h 30m
Mon 10/56:55 pm -
1 stop4h 21m
Deal found 9/16![United Airlines logo]()
$377
Last-minute flights from Memphis to Des MoinesDiscover last-minute flight deals from Memphis to Des Moines. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Memphis to Des Moines. Data last updated September 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:04 am -
1 stop5h 30m
Mon 10/56:55 pm -
1 stop4h 21m
Deal found 9/16![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:40 pm -
1 stop5h 32m
Mon 10/54:12 pm -
1 stop6h 59m
Deal found 9/15![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:36 pm -
1 stop6h 47m
Wed 10/211:27 pm -
1 stop7h 38m
Deal found 9/15![United Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:16 pm -
1 stop7h 32m
Mon 10/266:45 pm -
1 stop4h 59m
Deal found 9/18![United Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:16 pm -
1 stop7h 32m
Sun 10/258:00 am -
1 stop6h 53m
Deal found 9/18![United Airlines logo]()
$336
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
1 stop5h 23m
Mon 10/262:01 pm -
2 stops7h 41m
Deal found 9/18![American Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:40 pm -
2 stops9h 40m
Sun 11/15:25 am -
1 stop6h 20m
Deal found 9/18![Southwest logo]()
$403
One-way flights from Memphis to Des MoinesSearch for one-way flight options from Memphis to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Memphis to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:35 am -
1 stop5h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$117
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:09 pm -
1 stop4h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$133
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:25 pm -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$146
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:08 pm -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$148
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:32 am -
2 stops9h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$157
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:35 pm -
1 stop26h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$196
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:27 pm -
2 stops8h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:58 pm -
3 stops42h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$218
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1212:40 pm -
2 stops9h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$225
Find flight deals from Memphis to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $297 (United Airlines) |
One-way from | $117 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Mon 10/12
6:25 pm-11:35 pm
1 stop5h 10m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Mon 10/12
12:40 pm-10:10 pm
2 stops9h 30m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$225
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Mon 10/12
7:58 pm-7:38 am
3 stops59h 40m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Fri 10/23
4:16 pm-11:48 pm
1 stop7h 32m
Des Moines
Mon 10/26
6:45 pm-11:44 pm
1 stop4h 59m
$297
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Tue 10/20
2:36 pm-9:23 pm
1 stop6h 47m
Des Moines
Wed 10/21
1:27 pm-9:05 pm
1 stop7h 38m
$303
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 9/24
5:45 am-1:45 pm
2 stops8h 00m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Sat 9/26
6:00 am-5:48 pm
2 stops11h 48m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Wed 9/23
6:45 am-4:19 pm
2 stops9h 34m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Thu 10/1
7:04 am-12:34 pm
1 stop5h 30m
Des Moines
Mon 10/5
6:55 pm-11:16 pm
1 stop4h 21m
$377
Quickest round-trip
MemphisDes Moines
MEM Memphis - DSM Des Moines
MEMDSM
Memphis
Mon 9/21
9:47 am-2:20 pm
1 stop4h 33m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$399
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Memphis to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Memphis to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Memphis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Memphis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Memphis-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Memphis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Memphis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Memphis to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
MEM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 19, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
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Memphis and Des Moines flights
Browse other Memphis and Des Moines flight options. Last updated on September 19, 2026.
Other flights from Memphis
Browse through other flights departing from Memphis. Flights are based on user searches made on Cheapflights and were last updated on September 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Memphis to Des Moines
Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$452 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$279 | Average$486 | FlexibilityNo cancel fee | On-time71% |