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Des Moines

$136+ Cheap flights from Memphis to Des Moines (MEM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
giu 7 — giu 141
dom 6/7
dom 6/14
1 adult, Economy
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Cheap flight deals from Memphis to Des Moines

Cheapest flights from Memphis to Des Moines
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maggio 8, 2026.

This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 6/15:05 am
MEM
-
DSM
1 stop6h 40m
Southwest
mer 6/35:30 am
DSM
-
MEM
1 stop6h 15m
Southwest
Deal found 5/4$278
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 8/185:45 am
MEM
-
DSM
1 stop4h 26m
United Airlines
mer 8/191:40 pm
DSM
-
MEM
1 stop7h 09m
United Airlines
Deal found 5/4$341
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/56:07 am
MEM
-
DSM
1 stop6h 50m
American Airlines
dom 6/77:02 pm
DSM
-
MEM
1 stop4h 57m
American Airlines
Deal found 5/6$347
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/2412:01 pm
MEM
-
DSM
1 stop6h 20m
American Airlines
mer 5/276:02 am
DSM
-
MEM
2 stops8h 05m
American Airlines
Deal found 5/7$352
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 10/304:50 pm
MEM
-
DSM
2 stops6h 40m
Southwest
lun 11/26:40 am
DSM
-
MEM
2 stops15h 20m
Southwest
Deal found 5/7$363

Find flight deals from Memphis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated maggio 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$278
(Southwest)

One-way from

$136
(Delta)

Popular in

July

Cheapest in

September

Average price

$346
Provider with most accurate pricing for Memphis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Memphis-Des Moines flights.
Search Deals
From Memphis to Des Moines
Search Deals
One-way flight from Memphis to Des Moines
Search Deals
High demand for flights, 4% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maggio 8, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

lun 6/1

5:05 am-11:45 am

1 stop6h 40m

Des Moines

mer 6/3

5:30 am-5:30 pm

2 stops12h 00m

$283
Quickest round-trip

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar 8/18

5:45 am-10:11 am

1 stop4h 26m

Des Moines

mer 8/19

9:14 am-2:35 pm

1 stop5h 21m

$341

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

ven 6/5

4:10 pm-12:12 am

1 stop8h 02m

Des Moines

dom 6/7

7:02 pm-11:59 pm

1 stop4h 57m

$347

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

dom 5/24

7:22 am-2:24 pm

1 stop7h 02m

Des Moines

mer 5/27

9:14 am-2:29 pm

1 stop5h 15m

$347

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

ven 10/30

6:10 am-1:10 pm

1 stop7h 00m

Des Moines

lun 11/2

4:25 pm-11:20 pm

1 stop6h 55m

$347

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

dom 5/24

12:01 pm-6:21 pm

1 stop6h 20m

Des Moines

mer 5/27

6:02 am-2:07 pm

2 stops8h 05m

$352
Cheapest one-way

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar 6/23

5:48 pm-12:35 am

1 stop6h 47m

$136

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar 6/23

12:25 pm-10:45 pm

2 stops10h 20m

$147

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mer 6/24

12:25 pm-9:40 pm

2 stops9h 15m

$189

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

gio 5/21

7:05 am-12:52 pm

1 stop5h 47m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Memphis to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Memphis to Des Moines in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Memphis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Memphis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Memphis-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Memphis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Memphis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Memphis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Memphis to Des Moines

How much does it cost to fly round-trip from Memphis to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated maggio 8, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,459 reviews

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,459 reviews
Delta
7.9
Good
8,459 reviews

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,672 reviews
Delta
7.9
Good
8,459 reviews

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Memphis to Des Moines?

    Airlines like Southwest and United Airlines fly from Memphis to Des Moines in about 4h 26m. The time it takes to get you to your destination can typically vary by up to 2h 14m. There are 491 mi between Memphis and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Memphis to Des Moines round-trip?

    Currently priced at $185, American Airlines will fly you from Memphis to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $201. These flights start at 53% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Memphis to Des Moines one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $98. United Airlines flights start at $125 while deals on American Airlines start at $153 one-way.

  • Can I find deals for flights from Memphis to Des Moines that include hotel bookings?

    Yes. In addition to deals on Memphis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Memphis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Memphis to Des Moines.

  • Can I find deals for business class flights from Memphis to Des Moines?

    Yes. Cheapflights offers flight deals from Memphis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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Top 2 airlines flying from Memphis to Des Moines

Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maggio 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$185Average$357FlexibilityNo cancel feeOn-time71%
DeltaCheapest$201Average$452FlexibilityNo cancel feeOn-timeN/A

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