$140+ Cheap flights from Des Moines to Memphis (DSM - MEM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Memphis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Memphis
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Cheapest flights from Des Moines to MemphisExplore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:00 am -
1 stop5h 09m
Mon 12/145:05 pm -
1 stop5h 16m
Deal found 9/9![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am -
2 stops9h 05m
Wed 10/283:15 pm -
1 stop6h 45m
Deal found 9/10![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:20 am -
2 stops7h 35m
Mon 12/145:55 am -
2 stops8h 20m
Deal found 9/9![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:26 am -
1 stop4h 21m
Sun 11/15:12 am -
1 stop5h 29m
Deal found 9/9![American Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 am -
2 stops6h 50m
Sun 11/16:05 am -
1 stop7h 05m
Deal found 9/9![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
2 stops10h 05m
Mon 11/92:40 pm -
1 stop7h 15m
Deal found 9/9![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:01 pm -
1 stop6h 42m
Mon 11/93:53 pm -
1 stop6h 42m
Deal found 9/12![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop5h 55m
Mon 11/92:20 pm -
2 stops8h 45m
Deal found 9/12![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 59m
Fri 10/309:51 am -
1 stop7h 36m
Deal found 9/10![United Airlines logo]()
$369
Best flights from Des Moines to MemphisDiscover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:00 am -
1 stop5h 09m
Mon 12/145:05 pm -
1 stop5h 16m
Deal found 9/9![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:12 pm -
1 stop6h 59m
Wed 10/285:52 pm -
1 stop6h 22m
Deal found 9/10![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:00 am -
1 stop7h 10m
Mon 12/142:50 pm -
2 stops7h 10m
Deal found 9/9![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
2 stops10h 05m
Mon 11/92:40 pm -
1 stop7h 15m
Deal found 9/9![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:45 am -
1 stop7h 21m
Mon 12/145:36 pm -
1 stop6h 50m
Deal found 9/12![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
1 stop5h 55m
Mon 11/92:20 pm -
2 stops8h 45m
Deal found 9/12![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:25 am -
1 stop4h 22m
Mon 11/95:36 pm -
1 stop6h 50m
Deal found 9/12![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 59m
Fri 10/309:51 am -
1 stop7h 36m
Deal found 9/10![United Airlines logo]()
$369
Last-minute flights from Des Moines to MemphisDiscover last-minute flight deals from Des Moines to Memphis. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Memphis. Data last updated September 13, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:30 pm -
1 stop7h 25m
Sun 10/115:10 am -
1 stop6h 10m
Deal found 9/10![Southwest logo]()
$422
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:12 pm -
1 stop6h 59m
Wed 10/285:52 pm -
1 stop6h 22m
Deal found 9/10![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am -
2 stops9h 05m
Wed 10/283:15 pm -
1 stop6h 45m
Deal found 9/10![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 59m
Fri 10/309:51 am -
1 stop7h 36m
Deal found 9/10![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:26 am -
1 stop4h 21m
Sun 11/15:12 am -
1 stop5h 29m
Deal found 9/9![American Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 am -
2 stops6h 50m
Sun 11/16:05 am -
1 stop7h 05m
Deal found 9/9![Southwest logo]()
$353
One-way flights from Des Moines to MemphisSearch for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:07 pm -
1 stop4h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$140
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:54 pm -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$179
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:27 am -
2 stops12h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:30 pm -
2 stops7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:48 pm -
3 stops53h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:00 am -
3 stops29h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Allegiant Air logo]()
$562
Find flight deals from Des Moines to Memphis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (United Airlines) |
One-way from | $140 (Delta) |
Popular in | November |
Cheapest in | August |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 10/10
4:07 pm-8:35 pm
1 stop4h 28m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 10/10
11:27 am-11:49 pm
2 stops12h 22m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$180
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Fri 10/30
4:30 pm-11:35 pm
2 stops7h 05m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$225
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 12/12
9:00 am-2:09 pm
1 stop5h 09m
Memphis
Mon 12/14
5:05 pm-10:21 pm
1 stop5h 16m
$279
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Wed 10/21
4:12 pm-11:11 pm
1 stop6h 59m
Memphis
Wed 10/28
5:52 pm-12:14 am
1 stop6h 22m
$279
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Fri 10/30
2:48 pm-8:09 pm
3 stops53h 21m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$309
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 12/12
7:00 am-2:10 pm
1 stop7h 10m
Memphis
Mon 12/14
2:50 pm-10:00 pm
2 stops7h 10m
$314
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Tue 11/3
8:00 am-6:05 pm
2 stops10h 05m
Memphis
Mon 11/9
2:40 pm-9:55 pm
1 stop7h 15m
$354
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 12/12
9:45 am-5:06 pm
1 stop7h 21m
Memphis
Mon 12/14
5:36 pm-12:26 am
1 stop6h 50m
$357
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Tue 11/3
9:25 am-1:47 pm
1 stop4h 22m
Memphis
Mon 11/9
5:36 pm-12:26 am
1 stop6h 50m
$357
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Memphis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Memphis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Memphis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Memphis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Memphis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Memphis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Memphis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Memphis
Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
DSM-MEM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Memphis
What is the cheapest month to book a flight from Des Moines to Memphis?
Currently, August is the cheapest month in which you can book a flight from Des Moines to Memphis (average of $226). Flying from Des Moines to Memphis in November is currently the most expensive (average of $403). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Memphis?
Airfare is below average for this route at the moment.
Des Moines to Memphis flights typically cost between $386 and $432 in December.The cheapest round-trip price found within the last 5 days was $279 on United Airlines (Dec 12-Dec 14).
Reviews of airlines servicing Memphis
Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated September 13, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Crew
8.5
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Memphis?
Book flights to Memphis if you plan to visit one of these locationsSouthaven
Forrest City
Cordova
Batesville
West Memphis
Marion
Germantown
Horn Lake
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Other flights to Memphis
Explore flights to Memphis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
Des Moines and Memphis flights
Browse other Des Moines and Memphis flight options. Last updated on September 13, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 13, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Memphis
Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$338 | FlexibilityNo cancel fee | On-time71% |