$105+ Cheap flights from Des Moines to Memphis (DSM - MEM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
Nov 28 — Dec 51
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Memphis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Memphis
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Cheapest flights from Des Moines to MemphisExplore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:23 am -
1 stop4h 33m
Mon 12/75:58 pm -
1 stop5h 32m
Deal found 10/27![American Airlines logo]()
$247
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Tue 12/12:24 pm -
1 stop4h 30m
Deal found 10/24![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Mon 11/305:37 pm -
1 stop6h 42m
Deal found 10/25![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:00 am -
1 stop5h 39m
Mon 11/162:40 pm -
1 stop7h 15m
Deal found 10/26![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops9h 05m
Tue 12/15:25 am -
1 stop6h 00m
Deal found 10/24![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:58 pm -
2 stops7h 57m
Mon 11/165:36 pm -
1 stop6h 50m
Deal found 10/26![American Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:20 pm -
1 stop6h 28m
Sat 12/59:05 am -
2 stops12h 20m
Deal found 10/25![United Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:25 pm -
1 stop4h 59m
Sat 11/286:50 am -
1 stop6h 38m
Deal found 10/24![American Airlines logo]()
$406
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:30 am -
2 stops12h 26m
Mon 12/711:30 am -
2 stops9h 55m
Deal found 10/24![United Airlines logo]()
$427
Best flights from Des Moines to MemphisDiscover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
Discover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:23 am -
1 stop4h 33m
Mon 12/75:58 pm -
1 stop5h 32m
Deal found 10/27![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops9h 05m
Tue 12/15:25 am -
1 stop6h 00m
Deal found 10/24![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:20 pm -
1 stop6h 28m
Sat 12/59:05 am -
2 stops12h 20m
Deal found 10/25![United Airlines logo]()
$390
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Tue 12/12:24 pm -
1 stop4h 30m
Deal found 10/24![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Mon 11/305:37 pm -
1 stop6h 42m
Deal found 10/25![American Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops9h 05m
Mon 11/304:35 pm -
1 stop7h 00m
Deal found 10/25![Southwest logo]()
$453
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:58 pm -
2 stops7h 57m
Mon 11/165:36 pm -
1 stop6h 50m
Deal found 10/26![American Airlines logo]()
$383
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:30 am -
2 stops10h 35m
Mon 12/711:30 am -
2 stops9h 55m
Deal found 10/27![United Airlines logo]()
$478
Last-minute flights from Des Moines to MemphisDiscover last-minute flight deals from Des Moines to Memphis. Data last updated October 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Memphis. Data last updated October 29, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
1 stop7h 00m
Fri 11/136:05 am -
1 stop7h 05m
Deal found 10/25![Southwest logo]()
$509
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:00 am -
1 stop5h 39m
Mon 11/162:40 pm -
1 stop7h 15m
Deal found 10/26![United Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:58 pm -
2 stops7h 57m
Mon 11/165:36 pm -
1 stop6h 50m
Deal found 10/26![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
2 stops7h 20m
Mon 11/162:50 pm -
2 stops7h 15m
Deal found 10/26![Southwest logo]()
$473
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:25 pm -
1 stop4h 59m
Sat 11/286:50 am -
1 stop6h 38m
Deal found 10/24![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Tue 12/12:24 pm -
1 stop4h 30m
Deal found 10/24![American Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:23 am -
1 stop5h 46m
Mon 11/305:37 pm -
1 stop6h 42m
Deal found 10/25![American Airlines logo]()
$356
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops9h 05m
Tue 12/15:25 am -
1 stop6h 00m
Deal found 10/24![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:10 am -
2 stops9h 05m
Mon 11/304:35 pm -
1 stop7h 00m
Deal found 10/25![Southwest logo]()
$453
One-way flights from Des Moines to MemphisSearch for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
Search for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop23h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Frontier logo]()
$105
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:15 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$148
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:00 am -
1 stop6h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Southwest logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:25 pm -
2 stops44h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:13 pm -
2 stops42h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:45 pm -
1 stop4h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:26 pm -
1 stop4h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
3 stops18h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:46 pm -
2 stops30h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$404
Find flight deals from Des Moines to Memphis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (American Airlines) |
One-way from | $132 (Southwest) |
Popular in | October |
Cheapest in | August |
Average price | $820 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Wed 12/23
7:15 pm-11:15 pm
1 stop4h 00m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sat 12/5
9:23 am-1:56 pm
1 stop4h 33m
Memphis
Mon 12/7
5:58 pm-11:30 pm
1 stop5h 32m
$247
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Mon 11/9
4:25 pm-11:45 pm
2 stops7h 20m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$260
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Thu 11/26
6:10 am-3:15 pm
2 stops9h 05m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$260
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Fri 11/6
10:25 pm-7:09 pm
2 stops44h 44m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$278
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Wed 12/23
8:13 pm-2:33 pm
2 stops42h 20m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$279
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Thu 11/26
5:23 am-11:09 am
1 stop5h 46m
Memphis
Tue 12/1
2:24 pm-6:54 pm
1 stop4h 30m
$295
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Sun 11/29
6:45 pm-11:44 pm
1 stop4h 59m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$302
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Fri 11/6
7:26 pm-11:59 pm
1 stop4h 33m
Memphis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$344
Des MoinesMemphis
DSM Des Moines - MEM Memphis
DSMMEM
Des Moines
Thu 11/26
5:23 am-11:09 am
1 stop5h 46m
Memphis
Mon 11/30
5:37 pm-12:19 am
1 stop6h 42m
$356
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Memphis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Memphis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Memphis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Memphis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Memphis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Memphis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Memphis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Memphis
Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
DSM-MEM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Memphis
Reviews of airlines servicing Memphis
Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated October 29, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Memphis?
Book flights to Memphis if you plan to visit one of these locationsSouthaven
West Memphis
Forrest City
Cordova
Batesville
Germantown
Horn Lake
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Complete your trip to Memphis by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Memphis
Explore flights to Memphis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Des Moines and Memphis flights
Browse other Des Moines and Memphis flight options. Last updated on October 29, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Memphis
Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$263 | Average$370 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$337 | FlexibilityNo cancel fee | On-time71% |