$140+ Cheap flights from Des Moines to Memphis (DSM - MEM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEM
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Memphis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Memphis
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Best
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One-way
Cheapest flights from Des Moines to MemphisExplore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Des Moines to Memphis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:31 am
DSM
- MEM
1 stop5h 33m
Delta
Thu 9/176:00 am
MEM
- DSM
1 stop4h 17m
Delta
Deal found 7/27![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am
DSM
- MEM
1 stop6h 10m
Southwest
Sat 10/2412:05 pm
MEM
- DSM
2 stops8h 40m
Southwest
Deal found 7/24![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm
DSM
- MEM
1 stop6h 40m
Southwest
Fri 9/185:15 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 7/27![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:22 pm
DSM
- MEM
1 stop4h 28m
American Airlines
Sun 9/65:20 pm
MEM
- DSM
1 stop5h 47m
American Airlines
Deal found 7/27![American Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm
DSM
- MEM
1 stop7h 10m
Southwest
Fri 9/1811:20 am
MEM
- DSM
2 stops10h 55m
Southwest
Deal found 7/28![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:25 pm
DSM
- MEM
2 stops7h 30m
Southwest
Mon 8/3112:20 pm
MEM
- DSM
2 stops9h 50m
Southwest
Deal found 7/25![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:40 am
DSM
- MEM
2 stops10h 30m
Southwest
Sun 9/61:40 pm
MEM
- DSM
1 stop7h 35m
Southwest
Deal found 7/27![Southwest logo]()
$325
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:40 am
DSM
- MEM
2 stops15h 20m
Southwest
Wed 11/115:30 am
MEM
- DSM
2 stops8h 40m
Southwest
Deal found 7/28![Southwest logo]()
$334
Best flights from Des Moines to MemphisDiscover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Des Moines to Memphis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am
DSM
- MEM
2 stops8h 30m
Southwest
Sat 10/2412:05 pm
MEM
- DSM
2 stops8h 40m
Southwest
Deal found 7/24![Southwest logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:08 pm
DSM
- MEM
1 stop6h 37m
American Airlines
Sat 8/151:11 pm
MEM
- DSM
1 stop8h 55m
American Airlines
Deal found 7/27![American Airlines logo]()
$469
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm
DSM
- MEM
1 stop6h 40m
Southwest
Fri 9/185:15 am
MEM
- DSM
1 stop6h 10m
Southwest
Deal found 7/26![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am
DSM
- MEM
1 stop6h 00m
Southwest
Mon 8/3112:20 pm
MEM
- DSM
2 stops9h 50m
Southwest
Deal found 7/25![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:25 pm
DSM
- MEM
1 stop7h 10m
Southwest
Fri 9/1811:20 am
MEM
- DSM
2 stops10h 55m
Southwest
Deal found 7/28![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:25 pm
DSM
- MEM
1 stop7h 05m
Southwest
Sun 8/3012:40 pm
MEM
- DSM
2 stops10h 10m
Southwest
Deal found 7/28![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:25 pm
DSM
- MEM
2 stops7h 30m
Southwest
Fri 8/143:20 pm
MEM
- DSM
1 stop6h 50m
Southwest
Deal found 7/26![Southwest logo]()
$474
Last-minute flights from Des Moines to MemphisDiscover last-minute flight deals from Des Moines to Memphis. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Memphis. Data last updated July 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:13 pm
DSM
- MEM
1 stop6h 37m
American Airlines
Mon 8/106:32 am
MEM
- DSM
1 stop5h 52m
American Airlines
Deal found 7/25![American Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:50 pm
DSM
- MEM
1 stop4h 31m
United Airlines
Mon 8/1011:46 am
MEM
- DSM
2 stops8h 44m
United Airlines
Deal found 7/24![United Airlines logo]()
$544
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:25 pm
DSM
- MEM
2 stops7h 30m
Southwest
Fri 8/143:20 pm
MEM
- DSM
1 stop6h 50m
Southwest
Deal found 7/26![Southwest logo]()
$474
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:40 pm
DSM
- MEM
1 stop7h 16m
United Airlines
Fri 8/147:15 am
MEM
- DSM
1 stop7h 01m
United Airlines
Deal found 7/23![United Airlines logo]()
$503
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:22 pm
DSM
- MEM
1 stop4h 28m
American Airlines
Sun 8/306:41 pm
MEM
- DSM
1 stop5h 07m
American Airlines
Deal found 7/28![American Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:25 pm
DSM
- MEM
1 stop7h 05m
Southwest
Sun 8/3012:40 pm
MEM
- DSM
2 stops10h 10m
Southwest
Deal found 7/28![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am
DSM
- MEM
1 stop6h 00m
Southwest
Mon 8/313:20 pm
MEM
- DSM
1 stop6h 50m
Southwest
Deal found 7/25![Southwest logo]()
$304
One-way flights from Des Moines to MemphisSearch for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Des Moines to Memphis. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:10 pm
DSM
- MEM
1 stop5h 40m
American Airlines
Deal found 7/27![American Airlines logo]()
$140
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:35 am
DSM
- MEM
2 stops9h 05m
Southwest
Deal found 7/26![Southwest logo]()
$145
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
DSM
- MEM
2 stops7h 45m
Southwest
Deal found 7/27![Southwest logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:31 pm
DSM
- MEM
3 stops28h 29m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:00 am
DSM
- MEM
3 stops34h 23m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$233
Find flight deals from Des Moines to Memphis
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Memphis (MEM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Delta) |
One-way from | $140 (American Airlines) |
Popular in | July |
Cheapest in | August |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Memphis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Des Moines to Memphis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Wed 10/21
5:35 am-2:05 pm
2 stops8h 30m
Memphis
Sat 10/24
12:05 pm-8:45 pm
2 stops8h 40m
$289
Quickest round-trip
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Mon 9/14
3:50 pm-10:30 pm
1 stop6h 40m
Memphis
Fri 9/18
5:15 am-11:25 am
1 stop6h 10m
$304
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Fri 8/28
5:40 am-11:40 am
1 stop6h 00m
Memphis
Mon 8/31
12:20 pm-10:10 pm
2 stops9h 50m
$309
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Fri 9/11
2:25 pm-9:35 pm
1 stop7h 10m
Memphis
Fri 9/18
11:20 am-10:15 pm
2 stops10h 55m
$311
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Fri 8/21
2:25 pm-9:30 pm
1 stop7h 05m
Memphis
Sun 8/30
12:40 pm-10:50 pm
2 stops10h 10m
$358
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Tue 8/11
1:08 pm-7:45 pm
1 stop6h 37m
Memphis
Sat 8/15
1:11 pm-10:06 pm
1 stop8h 55m
$469
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Mon 8/10
2:25 pm-9:55 pm
2 stops7h 30m
Memphis
Fri 8/14
3:20 pm-10:10 pm
1 stop6h 50m
$474
Cheapest one-way
Quickest one-way
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Wed 10/21
6:54 pm-11:24 pm
1 stop4h 30m
$140
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Thu 8/20
5:10 pm-10:50 pm
1 stop5h 40m
$140
Des MoinesMemphis
DSM - MEM
DSMMEM
Des Moines
Wed 10/21
5:35 am-2:40 pm
2 stops9h 05m
$145
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Memphis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Memphis in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Memphis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Memphis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Memphis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Memphis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Memphis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Memphis
Have a flexible travel schedule? Discover the best time to fly to Memphis from Des Moines with our price prediction graph.
DSM-MEM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Memphis
Reviews of airlines servicing Memphis
Get insights into the airlines that provide service to Memphis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Memphis. Reviews last updated July 29, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Memphis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Memphis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Memphis?
Book flights to Memphis if you plan to visit one of these locationsSouthaven
West Memphis
Forrest City
Cordova
Batesville
Marion
Germantown
Horn Lake
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Other flights to Memphis
Explore flights to Memphis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Des Moines and Memphis flights
Browse other Des Moines and Memphis flight options. Last updated on July 29, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Memphis
Discover the top 2 airlines that operate flights from Des Moines to Memphis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$257 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$338 | FlexibilityNo cancel fee | On-time71% |