$230+ Cheap flights from Des Moines (DSM) to Mexico City (MEX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jul 22 — Jul 291
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Mexico City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Mexico City
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Best
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Cheapest flights from Des Moines to Mexico CityExplore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 22, 2026.
Explore the most affordable flight options available from Des Moines to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MEX
1 stop28h 14m
Multiple Airlines
Wed 7/88:45 pm
MEX
- DSM
2 stops23h 47m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:49 pm
DSM
- MEX
1 stop8h 56m
Multiple Airlines
Tue 8/114:10 pm
MEX
- DSM
2 stops20h 24m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:44 pm
DSM
- MEX
1 stop25h 01m
Multiple Airlines
Thu 8/1311:05 am
MEX
- DSM
2 stops35h 09m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:49 pm
DSM
- MEX
1 stop8h 56m
Multiple Airlines
Wed 8/128:45 am
MEX
- DSM
2 stops30h 33m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$530
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:19 pm
DSM
- MEX
1 stop28h 11m
Multiple Airlines
Tue 8/184:15 pm
MEX
- DSM
2 stops43h 50m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$533
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- MEX
1 stop24h 44m
Multiple Airlines
Mon 7/2710:45 pm
MEX
- DSM
2 stops37h 14m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$551
Best flights from Des Moines to Mexico CityDiscover carefully curated flight deals from Des Moines to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 22, 2026.
Discover carefully curated flight deals from Des Moines to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 22, 2026.
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:35 pm
DSM
- MEX
1 stop8h 35m
United Airlines
Tue 8/182:15 pm
MEX
- DSM
1 stop7h 15m
United Airlines
Deal found 6/21![United Airlines logo]()
$622
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:13 pm
DSM
- MEX
1 stop17h 50m
American Airlines
Sat 8/85:35 am
MEX
- DSM
1 stop16h 50m
American Airlines
Deal found 6/17![American Airlines logo]()
$637
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:55 am
DSM
- MEX
2 stops13h 05m
Delta
Tue 8/116:50 am
MEX
- DSM
2 stops12h 49m
Delta
Deal found 6/19![Delta logo]()
$640
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
DSM
- MEX
2 stops8h 40m
United Airlines
Tue 8/188:05 am
MEX
- DSM
1 stop7h 14m
United Airlines
Deal found 6/21![United Airlines logo]()
$626
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am
DSM
- MEX
1 stop10h 06m
American Airlines
Sun 9/207:00 am
MEX
- DSM
1 stop10h 58m
American Airlines
Deal found 6/19![American Airlines logo]()
$654
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:20 am
DSM
- MEX
2 stops12h 30m
Delta
Sun 9/209:05 am
MEX
- DSM
2 stops12h 24m
Delta
Deal found 6/19![Delta logo]()
$680
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:00 am
DSM
- MEX
2 stops10h 50m
United Airlines
Sat 8/228:05 am
MEX
- DSM
1 stop7h 14m
United Airlines
Deal found 6/21![United Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:00 am
DSM
- MEX
2 stops12h 30m
Delta
Sat 8/158:50 am
MEX
- DSM
2 stops11h 09m
Delta
Deal found 6/21![Delta logo]()
$680
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:12 am
DSM
- MEX
2 stops10h 24m
American Airlines
Sat 8/155:00 am
MEX
- DSM
1 stop9h 12m
American Airlines
Deal found 6/21![American Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:40 pm
DSM
- MEX
1 stop8h 30m
United Airlines
Wed 7/224:40 am
MEX
- DSM
1 stop8h 30m
United Airlines
Deal found 6/21![United Airlines logo]()
$681
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:41 am
DSM
- MEX
2 stops10h 49m
Delta
Thu 8/136:25 am
MEX
- DSM
2 stops13h 14m
Delta
Deal found 6/21![Delta logo]()
$719
Last-minute flights from Des Moines to Mexico CityDiscover last-minute flight deals from Des Moines to Mexico City. Data last updated June 22, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Mexico City. Data last updated June 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MEX
1 stop28h 14m
Multiple Airlines
Wed 7/88:45 pm
MEX
- DSM
2 stops23h 47m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- MEX
1 stop24h 44m
Multiple Airlines
Mon 7/2710:45 pm
MEX
- DSM
2 stops37h 14m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:00 am
DSM
- MEX
2 stops25h 45m
Multiple Airlines
Wed 7/228:40 am
MEX
- DSM
2 stops30h 27m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$582
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:33 pm
DSM
- MEX
1 stop25h 12m
Multiple Airlines
Mon 8/318:10 am
MEX
- DSM
2 stops10h 54m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:40 pm
DSM
- MEX
1 stop8h 30m
United Airlines
Mon 8/3111:35 am
MEX
- DSM
1 stop9h 55m
United Airlines
Deal found 6/21![United Airlines logo]()
$649
This Aeromexico deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:41 am
DSM
- MEX
2 stops18h 19m
Aeromexico
Mon 7/279:35 pm
MEX
- DSM
2 stops23h 54m
Aeromexico
Deal found 6/20![Aeromexico logo]()
$636
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:12 am
DSM
- MEX
1 stop14h 23m
American Airlines
Sat 8/155:00 am
MEX
- DSM
1 stop9h 12m
American Airlines
Deal found 6/21![American Airlines logo]()
$656
One-way flights from Des Moines to Mexico CitySearch for one-way flight options from Des Moines to Mexico City. Find affordable one-way fares based on user searches. Data last updated June 22, 2026.
Search for one-way flight options from Des Moines to Mexico City. Find affordable one-way fares based on user searches. Data last updated June 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm
DSM
- MEX
1 stop21h 40m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:36 pm
DSM
- MEX
1 stop26h 09m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm
DSM
- MEX
1 stop22h 34m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$248
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:41 am
DSM
- MEX
1 stop12h 54m
American Airlines
Deal found 6/21![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:55 am
DSM
- MEX
2 stops12h 30m
Delta
Deal found 6/18![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:13 pm
DSM
- MEX
1 stop16h 07m
American Airlines
Deal found 6/19![American Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
DSM
- MEX
2 stops13h 25m
Delta
Deal found 6/22![Delta logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:03 pm
DSM
- MEX
1 stop17h 57m
American Airlines
Deal found 6/17![American Airlines logo]()
$376
Find flight deals from Des Moines to Mexico City
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $513 (Kiwi.com) |
One-way from | $230 (Kiwi.com) |
Popular in | December |
Cheapest in | March |
Average price | $764 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Tue 8/11
1:35 pm-9:10 pm
1 stop8h 35m
Mexico City Benito Juarez
Tue 8/18
2:15 pm-10:30 pm
1 stop7h 15m
$622
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Wed 8/12
8:00 am-3:40 pm
2 stops8h 40m
Mexico City Benito Juarez
Tue 8/18
8:05 am-4:19 pm
1 stop7h 14m
$626
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Sat 8/1
7:13 pm-12:03 pm
1 stop17h 50m
Mexico City Benito Juarez
Sat 8/8
5:35 am-11:25 pm
1 stop16h 50m
$637
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Tue 8/4
6:55 am-7:00 pm
2 stops13h 05m
Mexico City Benito Juarez
Tue 8/11
6:50 am-8:39 pm
2 stops12h 49m
$640
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Tue 8/11
8:00 am-5:50 pm
2 stops10h 50m
Mexico City Benito Juarez
Sat 8/22
8:05 am-4:19 pm
1 stop7h 14m
$649
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Fri 9/11
5:30 am-2:36 pm
1 stop10h 06m
Mexico City Benito Juarez
Sun 9/20
7:00 am-6:58 pm
1 stop10h 58m
$654
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Fri 9/11
10:20 am-9:50 pm
2 stops12h 30m
Mexico City Benito Juarez
Sun 9/20
9:05 am-10:29 pm
2 stops12h 24m
$680
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Fri 7/31
6:00 am-5:30 pm
2 stops12h 30m
Mexico City Benito Juarez
Sat 8/15
8:50 am-8:59 pm
2 stops11h 09m
$680
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Tue 7/14
1:40 pm-9:10 pm
1 stop8h 30m
Mexico City Benito Juarez
Wed 7/22
4:40 am-2:10 pm
1 stop8h 30m
$681
Des MoinesMexico City
DSM - MEX
DSMMEX
Des Moines
Fri 7/31
5:12 am-2:36 pm
2 stops10h 24m
Mexico City Benito Juarez
Sat 8/15
5:00 am-3:12 pm
1 stop9h 12m
$709
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Mexico City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Mexico City in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Mexico City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Mexico City
Have a flexible travel schedule? Discover the best time to fly to Mexico City from Des Moines with our price prediction graph.
DSM-MEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Mexico City
What is the cheapest month to book a flight from Des Moines to Mexico City?
Currently, March is the cheapest month in which you can book a flight from Des Moines to Mexico City (average of $549). Flying from Des Moines to Mexico City in December is currently the most expensive (average of $1,019). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Mexico City?
Reviews of airlines servicing Mexico City
Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated June 22, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Des Moines to Mexico City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.4
Food
6.6
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Overall
7.4
Food
6.6
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Crew
8.1
Overall
7.4
Food
6.6
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Mexico City?
Book flights to Mexico City if you plan to visit one of these locationsTaxco
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Complete your trip
Complete your trip to Mexico City by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Mexico City
Explore flights to Mexico City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 22, 2026.
Des Moines and Mexico City flights
Browse other Des Moines and Mexico City flight options. Last updated on June 22, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on June 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Mexico City
Discover the top 2 airlines that operate flights from Des Moines to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$379 | Average$659 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$540 | Average$689 | FlexibilityNo cancel fee | On-time71% |