What are the cheapest airlines flying from Mexico City to Des Moines round-trip?

Our cheapest airline available from Mexico City to Des Moines is Delta. Our recent data shows that you can find tickets from as low as $500 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $502 and $571 round-trip. Delta is 16% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Mexico City to Des Moines one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $356. Users have also found prices from $359 and $423 on United Airlines and Aeromexico, respectively.

What is the cheapest month to book a flight from Mexico City to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $336). Flying from Mexico City to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Mexico City to Des Moines?

Travelers seeking maximum savings on their Mexico City to Des Moines flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What is the cheapest day to fly round-trip from Mexico City to Des Moines?

Users have found that leaving on a Thursday can be a cost-effective option. It’s possible to save up to 28% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Mexico City to Des Moines?

Our data shows that April tends to be the cheapest month to fly to Des Moines from Mexico City. Users have commonly found prices around $598 for the month, but tickets can be as low as $519. Due to multiple factors, prepare for potentially higher prices in August.

Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mexico City to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.

Can I find deals for business class flights from Mexico City to Des Moines?

Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$356+ Flights from Mexico City to Des Moines

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Cheap flight deals from Mexico City to Des Moines

Round-trip from	$500 (Delta)
One-way from	$356 (Delta)
Popular in	August
Cheapest in	April
Average price	$652

From Mexico City Benito Juarez to Des Moines

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One-way flight from Mexico City Benito Juarez to Des Moines

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Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2025.

lun. 9/87:15 amMEX - DSM

2 stops12h 44mDelta

mar. 9/235:44 amDSM - MEX

2 stops12h 46mDelta

Deal found 6/30

$500

lun. 8/114:40 pmMEX - DSM

1 stop20h 36mUnited Airlines

mar. 8/196:15 amDSM - MEX

1 stop5h 30mUnited Airlines

Deal found 7/1

$502

lun. 8/1112:35 pmMEX - DSM

1 stop9h 23mAmerican Airlines

dom. 8/175:12 amDSM - MEX

1 stop6h 08mAmerican Airlines

Deal found 7/2

$571

jue. 7/247:55 amMEX - DSM

2 stops13h 43mMultiple Airlines

jue. 7/316:32 pmDSM - MEX

3 stops28h 28mMultiple Airlines

Deal found 7/1

$572

mar. 8/1212:05 amMEX - DSM

2 stops16h 40mAeromexico

sáb. 8/167:00 amDSM - MEX

2 stops9h 25mAeromexico

Deal found 7/1

$621

dom. 9/712:15 amMEX - DSM

2 stops15h 59mAir Canada

mar. 9/231:10 pmDSM - MEX

2 stops11h 05mAir Canada

Deal found 6/30

$1,289

dom. 8/101:55 amMEX - DSM

2 stops55h 21mWestJet

mar. 8/196:00 amDSM - MEX

2 stops33h 35mWestJet

Deal found 7/1

$1,615

Best flights from Mexico City to Des Moines
Discover carefully curated flight deals from Mexico City to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated julio 2, 2025.

lun. 9/87:15 amMEX - DSM

2 stops12h 44mDelta

mar. 9/235:44 amDSM - MEX

2 stops12h 46mDelta

Deal found 6/30

$500

lun. 8/114:40 pmMEX - DSM

1 stop20h 36mUnited Airlines

mar. 8/196:15 amDSM - MEX

1 stop5h 30mUnited Airlines

Deal found 7/1

$502

lun. 8/1112:35 pmMEX - DSM

1 stop9h 23mAmerican Airlines

dom. 8/175:12 amDSM - MEX

1 stop6h 08mAmerican Airlines

Deal found 7/2

$571

jue. 7/247:55 amMEX - DSM

2 stops13h 43mMultiple Airlines

jue. 7/316:32 pmDSM - MEX

3 stops28h 28mMultiple Airlines

Deal found 7/1

$572

mar. 8/1212:05 amMEX - DSM

2 stops16h 40mAeromexico

sáb. 8/167:00 amDSM - MEX

2 stops9h 25mAeromexico

Deal found 7/1

$621

dom. 9/712:15 amMEX - DSM

2 stops15h 59mAir Canada

mar. 9/231:10 pmDSM - MEX

2 stops11h 05mAir Canada

Deal found 6/30

$1,289

dom. 8/101:55 amMEX - DSM

2 stops55h 21mWestJet

mar. 8/196:00 amDSM - MEX

2 stops33h 35mWestJet

Deal found 7/1

$1,615

Last-minute flights from Mexico City to Des Moines
Discover last-minute flight deals from Mexico City to Des Moines. Data last updated julio 2, 2025 and is based on user searches.

lun. 7/1412:15 amMEX - DSM

2 stops13h 26mAir Canada

mar. 7/156:50 pmDSM - MEX

2 stops29h 25mAir Canada

Deal found 7/1

$2,952

jue. 7/247:55 amMEX - DSM

2 stops13h 43mMultiple Airlines

jue. 7/316:32 pmDSM - MEX

3 stops28h 28mMultiple Airlines

Deal found 7/1

$572

dom. 8/101:55 amMEX - DSM

2 stops55h 21mWestJet

mar. 8/196:00 amDSM - MEX

2 stops33h 35mWestJet

Deal found 7/1

$1,615

lun. 8/119:10 amMEX - DSM

2 stops12h 29mDelta

mar. 8/197:00 amDSM - MEX

1 stop6h 40mDelta

Deal found 7/1

$500

lun. 8/114:40 pmMEX - DSM

1 stop20h 36mUnited Airlines

mar. 8/196:15 amDSM - MEX

1 stop5h 30mUnited Airlines

Deal found 7/1

$502

lun. 8/1112:35 pmMEX - DSM

1 stop9h 23mAmerican Airlines

dom. 8/175:12 amDSM - MEX

1 stop6h 08mAmerican Airlines

Deal found 7/2

$571

mar. 8/1212:05 amMEX - DSM

2 stops16h 40mAeromexico

sáb. 8/167:00 amDSM - MEX

2 stops9h 25mAeromexico

Deal found 7/1

$621

One-way flights from Mexico City to Des Moines
Search for one-way flight options from Mexico City to Des Moines. Find affordable one-way fares based on user searches. Data last updated julio 2, 2025.

mar. 8/129:25 amMEX - DSM

2 stops10h 32mDelta

Deal found 7/1

$356

mar. 8/122:10 pmMEX - DSM

1 stop7h 50mUnited Airlines

Deal found 7/1

$359

lun. 8/1112:05 amMEX - DSM

2 stops16h 40mAeromexico

Deal found 7/1

$423

sáb. 7/54:50 pmMEX - DSM

3 stops43h 59mMultiple Airlines

Deal found 7/1

$518

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

lun. 9/8

7:15 am-8:59 pm

2 stops12h 44m

Des Moines

mar. 9/23

5:44 am-5:30 pm

2 stops12h 46m

$500

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

lun. 8/11

4:40 pm-2:16 pm

1 stop20h 36m

Des Moines

mar. 8/19

6:15 am-10:45 am

1 stop5h 30m

$502

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

lun. 8/11

12:35 pm-10:58 pm

1 stop9h 23m

Des Moines

dom. 8/17

5:12 am-10:20 am

1 stop6h 08m

$571

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

jue. 7/24

7:55 am-10:38 pm

2 stops13h 43m

Des Moines

jue. 7/31

6:32 pm-10:00 pm

3 stops28h 28m

$572

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

mar. 8/12

12:05 am-5:45 pm

2 stops16h 40m

Des Moines

sáb. 8/16

7:00 am-3:25 pm

2 stops9h 25m

$621

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

dom. 9/7

12:15 am-5:14 pm

2 stops15h 59m

Des Moines

mar. 9/23

1:10 pm-11:15 pm

2 stops11h 05m

$1,289

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

dom. 8/10

1:55 am-10:16 am

2 stops55h 21m

Des Moines

mar. 8/19

6:00 am-2:35 pm

2 stops33h 35m

$1,615

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

mar. 8/12

9:25 am-8:57 pm

2 stops10h 32m

$356

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

mar. 8/12

2:10 pm-11:00 pm

1 stop7h 50m

$359

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

lun. 8/11

12:05 am-5:45 pm

2 stops16h 40m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Showing 1-10 of 11 results

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest time of day to fly from MEX to DSM?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mexico City to Des Moines as you normally would.

Reviews of airlines servicing Des Moines

Read through reviews of airlines operating flights from Mexico City to Des Moines, such as Delta, Aeromexico, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,975 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Aeromexico

7.5

Good

1,718 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,861 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

WestJet

7.2

Good

2,912 reviews

Delta

8.0

Very good

7,975 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Mexico City to Des Moines round-trip?
Our cheapest airline available from Mexico City to Des Moines is Delta. Our recent data shows that you can find tickets from as low as $500 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $502 and $571 round-trip. Delta is 16% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Mexico City to Des Moines one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $356. Users have also found prices from $359 and $423 on United Airlines and Aeromexico, respectively.
Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?
Yes. In addition to deals on Mexico City to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mexico City to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Des Moines.
Can I find deals for business class flights from Mexico City to Des Moines?
Yes. Cheapflights offers flight deals from Mexico City to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mexico City to Des Moines?
Currently, August is the cheapest month in which you can book a flight from Mexico City to Des Moines (average of $336). Flying from Mexico City to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Altoona

Ames

Johnston

Boone

West Des Moines

Ankeny

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$356+ Cheap flights from Mexico City (MEX) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mexico City to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Mexico City to Des Moines

Round-trip from

One-way from

Popular in

Cheapest in

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Find flight deals from Mexico City to Des Moines

Cheapest flights from Mexico City to Des MoinesExplore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2025.

Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Des Moines that are best for you.

Best time to book a flight from Mexico City to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Des Moines

What is the cheapest time of day to fly from MEX to DSM?

Find hourly flight availability from Mexico City to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 2, 2025.

Reviews of airlines servicing Des Moines

Read through reviews of airlines operating flights from Mexico City to Des Moines, such as Delta, Aeromexico, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Mexico City to Des Moines round-trip?

What are the cheapest airlines to fly from Mexico City to Des Moines one-way?

Can I find deals for flights from Mexico City to Des Moines that include hotel bookings?

How can I find direct flights from Mexico City to Des Moines?

Can I find deals for business class flights from Mexico City to Des Moines?

What is the cheapest month to book a flight from Mexico City to Des Moines?

Traveling to a place near Mexico City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mexico City to Des Moines

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Travel Smart

Cheapest flights from Mexico City to Des Moines
Explore the most affordable flight options available from Mexico City to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2025.