Mexico

$163+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CUN
Feb 18 — Feb 251
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Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated February 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$368
(eDestinos)

One-way from

$163
(Expedia)

Popular in

December

Cheapest in

April

Average price

$655
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
From Des Moines to Mexico
One-way flight from Des Moines to Mexico
Highest demand for flights based on searches. 7% potential increase in price ($55 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in February 2025

Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2025.

This eDestinos deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/31:27 pmDSM - MTY
1 stop9h 18mMultiple Airlines
Mon 4/289:08 amMTY - DSM
1 stop12h 47mMultiple Airlines
Deal found 2/13$368
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/303:30 pmDSM - MEX
1 stop30h 40mMultiple Airlines
Sun 4/63:45 pmMEX - DSM
2 stops30h 28mMultiple Airlines
Deal found 2/13$462
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/43:53 pmDSM - CUN
2 stops19h 27mMultiple Airlines
Sun 3/99:21 amCUN - DSM
1 stop9h 56mMultiple Airlines
Deal found 2/13$481
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:14 pmDSM - CUN
2 stops17h 41mDelta
Thu 11/278:10 amCUN - DSM
1 stop10h 28mDelta
Deal found 2/13$485
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/55:45 amDSM - SJD
1 stop9h 58mUnited Airlines
Sat 4/122:50 pmSJD - DSM
1 stop6h 52mUnited Airlines
Deal found 2/13$487
This Aeromexico deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/15:45 amDSM - CZM
1 stop8h 15mAeromexico
Tue 4/82:20 pmCZM - DSM
1 stop7h 39mAeromexico
Deal found 2/13$491
This SmartFares deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/102:14 pmDSM - CUN
1 stop5h 44mAeromexico
Tue 7/158:00 amCUN - DSM
1 stop9h 38mAeromexico
Deal found 2/12$496
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/283:44 pmDSM - GDL
2 stops20h 53mMultiple Airlines
Wed 3/58:15 pmGDL - DSM
2 stops26h 26mMultiple Airlines
Deal found 2/11$502
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/191:01 pmDSM - CUN
1 stop6h 42mAmerican Airlines
Mon 3/246:05 pmCUN - DSM
1 stop18h 26mAmerican Airlines
Deal found 2/13$515
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/277:00 amDSM - SJD
2 stops13h 23mDelta
Fri 5/212:15 pmSJD - DSM
1 stop8h 32mDelta
Deal found 2/13$516
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/235:29 pmDSM - MTY
1 stop16h 44mAmerican Airlines
Sun 3/305:00 amMTY - DSM
1 stop17h 51mAmerican Airlines
Deal found 2/13$523
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/255:00 amDSM - CZM
1 stop8h 54mAmerican Airlines
Fri 5/21:55 pmCZM - DSM
1 stop25h 52mAmerican Airlines
Deal found 2/13$525

Find flights from Des Moines to Mexico within your budget

Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2025.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Thu 4/3

1:27 pm-9:45 pm

1 stop9h 18m

Monterrey Gen Mariano Escobedo

Mon 4/28

9:08 am-10:55 pm

1 stop12h 47m

$368

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Sun 3/30

3:30 pm-9:10 pm

1 stop30h 40m

Mexico City Benito Juarez

Sun 4/6

3:45 pm-11:13 pm

2 stops30h 28m

$462

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 3/4

3:53 pm-12:20 pm

2 stops19h 27m

Cancun

Sun 3/9

9:21 am-7:17 pm

1 stop9h 56m

$481

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 3/23

5:45 am-6:40 pm

2 stops12h 55m

Cancun

Wed 3/26

8:00 am-9:20 pm

2 stops13h 20m

$485

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Sat 4/5

5:45 am-1:43 pm

1 stop9h 58m

San José del Cabo Los Cabos

Sat 4/12

2:50 pm-11:42 pm

1 stop6h 52m

$487

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 4/1

5:45 am-1:00 pm

1 stop8h 15m

Cozumel

Tue 4/8

2:20 pm-10:59 pm

1 stop7h 39m

$491

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 7/10

2:14 pm-7:58 pm

1 stop5h 44m

Cancun

Tue 7/15

8:00 am-5:38 pm

1 stop9h 38m

$496

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 2/28

3:44 pm-12:37 pm

2 stops20h 53m

Guadalajara Miguel Hidal

Wed 3/5

8:15 pm-10:41 pm

2 stops26h 26m

$502

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 3/19

1:01 pm-7:43 pm

1 stop6h 42m

Cancun

Mon 3/24

6:05 pm-12:31 pm

1 stop18h 26m

$515

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Sun 4/27

7:00 am-6:23 pm

2 stops13h 23m

San José del Cabo Los Cabos

Fri 5/2

12:15 pm-10:47 pm

1 stop8h 32m

$516

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Mexico

Get recent, data-driven insights about flights from Des Moines to Mexico including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $360). Flying from Des Moines to Mexico in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.