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$200+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated July 1, 2025.

Round-trip from

$283
(American Airlines)

One-way from

$211
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$560
From Des Moines to Mexico
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One-way flight from Des Moines to Mexico
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Highest demand for flights based on searches. 10% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/125:12 amDSM - SJD
1 stop7h 33mAmerican Airlines
Tue 8/191:16 pmSJD - DSM
1 stop8h 58mAmerican Airlines
Deal found 6/30$283
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/155:12 pmDSM - SJD
2 stops17h 36mUnited Airlines
Fri 7/181:12 pmSJD - DSM
1 stop8h 47mUnited Airlines
Deal found 7/1$325
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/182:49 pmDSM - SJD
2 stops22h 34mDelta
Fri 8/222:25 pmSJD - DSM
2 stops17h 53mDelta
Deal found 6/29$353
This Kissandfly.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:30 pmDSM - SJD
2 stops20h 50mKLM
Fri 8/222:25 pmSJD - DSM
2 stops21h 44mKLM
Deal found 7/1$368
This Kissandfly.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:30 pmDSM - SJD
2 stops20h 50mMultiple Airlines
Fri 8/221:46 pmSJD - DSM
1 stop6h 42mMultiple Airlines
Deal found 7/1$382
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/159:10 pmDSM - GDL
1 stop21h 01mMultiple Airlines
Fri 8/2210:20 amGDL - DSM
1 stop11h 22mMultiple Airlines
Deal found 7/1$389
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:05 pmDSM - CUN
1 stop6h 10mDelta
Wed 10/158:15 amCUN - DSM
1 stop9h 24mDelta
Deal found 6/30$397
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:52 pmDSM - CUN
1 stop16h 03mAmerican Airlines
Tue 11/183:00 pmCUN - DSM
1 stop20h 03mAmerican Airlines
Deal found 6/29$405
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:15 pmDSM - CUN
3 stops39h 55mMultiple Airlines
Thu 8/211:42 pmCUN - DSM
3 stops30h 59mMultiple Airlines
Deal found 6/30$408
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/159:10 pmDSM - MEX
1 stop23h 50mMultiple Airlines
Fri 8/2211:45 amMEX - DSM
1 stop9h 57mMultiple Airlines
Deal found 7/1$417
This eDestinos deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1010:31 pmDSM - MTY
2 stops34h 04mMultiple Airlines
Sun 8/1711:05 amMTY - DSM
1 stop6h 20mMultiple Airlines
Deal found 7/1$455
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:20 pmDSM - MID
1 stop19h 45mAmerican Airlines
Thu 8/212:45 pmMID - DSM
1 stop23h 16mAmerican Airlines
Deal found 7/1$466

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 8/12

5:12 am-10:45 am

1 stop7h 33m

San José del Cabo Los Cabos

Tue 8/19

1:16 pm-12:14 am

1 stop8h 58m

$283

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 8/18

2:49 pm-11:23 am

2 stops22h 34m

San José del Cabo Los Cabos

Fri 8/22

2:25 pm-10:18 am

2 stops17h 53m

$353

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Fri 8/15

6:30 pm-1:20 pm

2 stops20h 50m

San José del Cabo Los Cabos

Fri 8/22

2:25 pm-2:09 pm

2 stops21h 44m

$368

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Fri 8/15

6:30 pm-1:20 pm

2 stops20h 50m

San José del Cabo Los Cabos

Fri 8/22

1:46 pm-10:28 pm

1 stop6h 42m

$382

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 8/15

9:10 pm-5:11 pm

1 stop21h 01m

Guadalajara Miguel Hidal

Fri 8/22

10:20 am-10:42 pm

1 stop11h 22m

$389

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 8/14

7:15 pm-11:10 am

3 stops39h 55m

Cancun

Thu 8/21

1:42 pm-8:41 pm

3 stops30h 59m

$408

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 8/12

5:12 am-1:49 pm

1 stop8h 37m

Cancun

Tue 8/19

7:45 am-3:01 pm

1 stop7h 16m

$415

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 8/15

9:10 pm-8:00 pm

1 stop23h 50m

Mexico City Benito Juarez

Fri 8/22

11:45 am-10:42 pm

1 stop9h 57m

$417

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Sun 8/10

10:31 pm-7:35 am

2 stops34h 04m

Monterrey Gen Mariano Escobedo

Sun 8/17

11:05 am-6:25 pm

1 stop6h 20m

$455

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 8/12

8:00 am-10:11 am

3 stops28h 11m

San José del Cabo Los Cabos

Tue 8/19

1:46 pm-10:39 am

2 stops18h 53m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Showing 1-10 of 50 results
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $388). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico as you normally would.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated July 1, 2025.
See what other customers who have flown with Southwest, Delta, and KLM from Des Moines to Mexico have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,273 reviews
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,973 reviews
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
KLM
7.8
Good
1,366 reviews
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Aeromexico
7.5
Good
1,718 reviews
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,858 reviews
Southwest
8.0
Very good
4,273 reviews

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $211. Users have also found prices from $225 and $307 on United Airlines and Delta, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - Puerto Vallarta Ordaz when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $388). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$300Average$580FlexibilityNo cancel feeOn-timeN/A
AeromexicoCheapest$350Average$501FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$423Average$681FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$460Average$635FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$471Average$635FlexibilityNo cancel feeOn-time71%

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