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$123+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in April or January, booked 46 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
Thu 10/17:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/26$257
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1311:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
Thu 9/177:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/25$265
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
Sun 9/277:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/26$305
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm
DSM
-
CLT
1 stop5h 00m
Southwest
Sat 9/123:25 pm
CLT
-
DSM
1 stop5h 00m
Southwest
Deal found 7/22$321
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am
DSM
-
CLT
1 stop5h 50m
Southwest
Wed 9/912:35 pm
CLT
-
DSM
2 stops10h 20m
Southwest
Deal found 7/22$326
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:54 pm
DSM
-
CLT
1 stop27h 01m
Multiple Airlines
Thu 10/159:22 am
CLT
-
DSM
1 stop6h 20m
Multiple Airlines
Deal found 7/22$345
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/131:58 pm
DSM
-
CLT
1 stop17h 29m
Multiple Airlines
Thu 9/179:22 am
CLT
-
DSM
1 stop11h 35m
Multiple Airlines
Deal found 7/22$348
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
DSM
-
CLT
1 stop17h 53m
Multiple Airlines
Fri 9/119:59 pm
CLT
-
DSM
2 stops46h 58m
Multiple Airlines
Deal found 7/26$364
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:50 pm
DSM
-
CLT
1 stop5h 00m
Southwest
Thu 8/278:10 am
CLT
-
DSM
1 stop4h 15m
Southwest
Deal found 7/26$369
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:40 pm
DSM
-
CLT
1 stop5h 30m
Southwest
Sun 9/65:40 pm
CLT
-
DSM
1 stop5h 30m
Southwest
Deal found 7/25$371

Find flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$257
(CheapOair)

One-way from

$123
(Frontier)

Popular in

March

Cheapest in

April

Average price

$471

Good round-trip deal

$389 or less

Good one-way deal

$259 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
Search Deals
From Des Moines to Charlotte Douglas
Search Deals
One-way flight from Des Moines to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
Search Deals
Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/5

12:10 pm-6:10 pm

1 stop5h 00m

Charlotte Douglas

Sat 9/12

3:25 pm-7:25 pm

1 stop5h 00m

$321

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 10/13

3:00 pm-9:05 pm

1 stop5h 05m

Charlotte Douglas

Wed 10/21

1:10 pm-9:55 pm

2 stops9h 45m

$326

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/5

5:30 am-12:20 pm

1 stop5h 50m

Charlotte Douglas

Wed 9/9

12:35 pm-10:00 pm

2 stops10h 25m

$326

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/19

7:20 am-6:25 pm

2 stops10h 05m

Charlotte Douglas

Thu 9/24

1:05 pm-10:10 pm

2 stops10h 05m

$331

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 8/29

5:30 am-2:25 pm

2 stops7h 55m

Charlotte Douglas

Mon 8/31

6:35 am-1:45 pm

2 stops8h 10m

$331
Quickest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 8/12

6:10 am-11:55 am

1 stop4h 45m

Charlotte Douglas

Sat 8/22

3:25 pm-7:25 pm

1 stop5h 00m

$398

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 8/28

3:50 pm-9:50 pm

1 stop5h 00m

Charlotte Douglas

Sun 8/30

7:35 am-11:35 am

1 stop5h 00m

$443

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 9/12

6:24 am-2:18 pm

2 stops6h 54m

Charlotte Douglas

Mon 9/14

4:23 pm-11:33 pm

1 stop8h 10m

$466

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 9/23

8:00 am-6:56 pm

2 stops9h 56m

Charlotte Douglas

Sun 9/27

6:45 am-10:31 am

1 stop4h 46m

$546

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 9/11

6:24 am-2:18 pm

2 stops6h 54m

Charlotte Douglas

Mon 9/14

4:23 pm-11:33 pm

1 stop8h 10m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Charlotte

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 45 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $395). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $769). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 27, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Charlotte as you normally would.

How much does it cost to fly round-trip from Des Moines to Charlotte?

Airfare is below average for this route at the moment.

Des Moines to Charlotte flights typically cost between $373 and $581 in September.
The cheapest round-trip price found within the last 5 days was $257 on Frontier (Sep 24-Oct 1).

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated July 27, 2026.
See what other customers who have flown with Southwest and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Southwest
8.0
Very good
4,229 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
American Airlines
7.1
Good
11,837 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 22m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Des Moines to Douglas offered by 2 different airlines.

  • How popular is this Des Moines to Charlotte flight route?

    The Des Moines to Charlotte Douglas flight path was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 5h. Fly via Southwest to get the fastest option. There are 813 mi between Des Moines and Charlotte.

  • What are the cheapest airlines flying from Des Moines to Charlotte round-trip?

    Flying on Southwest is currently your cheapest option to Charlotte, with prices starting at $322. Another option worth looking into is American Airlines, starting at $351 round trip. Southwest is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $190. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $321 on average, our data indicates $395 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $395). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $769). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Rock Hill
Hickory
Gastonia
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Boone
Lancaster
Shelby
Gaffney
Fort Mill
Statesville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Des Moines to Charlotte

Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$322Average$450FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$351Average$465FlexibilityNo cancel feeOn-time71%

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