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$99+ Cheap flights from Des Moines to Charlotte (DSM - CLT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Find cheap flights from Des Moines to Charlotte with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in September or January, booked 46 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Des Moines to Charlotte

Cheapest flights from Des Moines to Charlotte
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:37 pm
DSM
-
CLT
1 stop17h 26m
Multiple Airlines
Thu 6/111:09 pm
CLT
-
DSM
1 stop9h 18m
Multiple Airlines
Deal found 4/21$220
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:07 pm
DSM
-
CLT
1 stop18h 58m
Multiple Airlines
Thu 6/119:37 am
CLT
-
DSM
1 stop12h 50m
Multiple Airlines
Deal found 4/21$223
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
-
CLT
2 stops24h 44m
Multiple Airlines
Mon 6/112:29 pm
CLT
-
DSM
1 stop11h 55m
Multiple Airlines
Deal found 4/23$238
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:57 pm
DSM
-
CLT
1 stop21h 14m
Multiple Airlines
Wed 6/33:16 pm
CLT
-
DSM
2 stops31h 11m
Multiple Airlines
Deal found 4/20$244
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:57 pm
DSM
-
CLT
1 stop19h 08m
Multiple Airlines
Fri 5/2912:29 pm
CLT
-
DSM
1 stop11h 55m
Multiple Airlines
Deal found 4/22$247
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:45 am
DSM
-
CLT
1 stop27h 20m
Multiple Airlines
Sun 5/2410:58 am
CLT
-
DSM
1 stop12h 33m
Multiple Airlines
Deal found 4/19$252
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:57 pm
DSM
-
CLT
1 stop18h 37m
Multiple Airlines
Mon 6/112:29 pm
CLT
-
DSM
1 stop11h 55m
Multiple Airlines
Deal found 4/22$255

Find flight deals from Des Moines to Charlotte

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$220
(Kiwi.com)

One-way from

$99
(Trip.com)

Popular in

March

Cheapest in

September

Average price

$411

Good round-trip deal

$429 or less

Good one-way deal

$214 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
Search Deals
From Des Moines to Charlotte Douglas
Search Deals
One-way flight from Des Moines to Charlotte Douglas
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Des Moines to Charlotte Douglas.
Search Deals
Price to beat on a one-way flight from Des Moines to Charlotte Douglas.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 5/17

7:45 am-12:05 pm

1 stop27h 20m

Charlotte Douglas

Sun 5/24

10:58 am-10:31 pm

1 stop12h 33m

$252

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 5/25

8:43 am-8:03 pm

1 stop10h 20m

Charlotte Douglas

Mon 5/25

10:50 pm-12:17 am

Nonstop2h 27m

$372
Quickest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 7/25

3:35 pm-8:45 pm

1 stop4h 10m

Charlotte Douglas

Wed 7/29

8:20 am-11:30 am

1 stop4h 10m

$411

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 7/25

10:54 am-4:27 pm

1 stop4h 33m

Charlotte Douglas

Tue 7/28

5:02 pm-8:49 pm

1 stop4h 47m

$411

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 6/13

3:35 pm-8:45 pm

1 stop4h 10m

Charlotte Douglas

Sat 6/20

6:00 pm-10:50 pm

1 stop5h 50m

$411

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 7/17

4:40 pm-9:50 pm

1 stop4h 10m

Charlotte Douglas

Sat 7/25

7:50 am-11:35 am

1 stop4h 45m

$417

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 6/19

5:10 am-10:55 am

1 stop4h 45m

Charlotte Douglas

Tue 6/23

8:35 am-11:30 am

1 stop3h 55m

$418

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 5/19

3:15 pm-8:55 pm

1 stop4h 40m

Charlotte Douglas

Sat 5/23

6:10 am-1:20 pm

2 stops8h 10m

$443

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 6/5

4:40 pm-11:15 pm

2 stops5h 35m

Charlotte Douglas

Sun 6/7

7:05 am-3:35 pm

2 stops9h 30m

$449

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 7/20

4:40 pm-9:50 pm

1 stop4h 10m

Charlotte Douglas

Fri 7/24

7:35 am-11:30 am

1 stop4h 55m

$459

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Des Moines to Charlotte

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Charlotte

Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Charlotte

How far ahead should I book a flight from Des Moines to Charlotte?

The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 45 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Charlotte?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $374). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $912). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to CLT?

Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Charlotte as you normally would.

How much does it cost to fly round-trip from Des Moines to Charlotte?

Reviews of airlines servicing Charlotte

Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated April 24, 2026.
See what other customers who have flown with American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Comfort

7.2

Food

6.4

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Susie,Jan 2026

DAY - CLT

We weren’t offered any beverages on this flight. It was not bumpy at all
American Airlines
7.1
Good
11,666 reviews
American Airlines
7.1
Good
11,666 reviews

Boarding

7.5

Comfort

7.2

Food

6.4

Entertainment

6.9

Crew

7.9

Overall

7.1

Reviews

1 / 20
10.0
Excellent

Susie,Jan 2026

DAY - CLT

We weren’t offered any beverages on this flight. It was not bumpy at all

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Des Moines to Charlotte?

    To fly from Des Moines to Charlotte, you need to book a flight from Des Moines (DSM) to Douglas (CLT). Nonstop flights to Charlotte Douglas from Des Moines take 2h 21m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Des Moines to Douglas offered by 1 airline.

  • How popular is this Des Moines to Charlotte flight route?

    The Des Moines to Charlotte Douglas flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to Charlotte?

    There are many flights that can get you from Des Moines to Charlotte in 4h 10m. Fly via American Airlines, Southwest, or Delta to get the fastest option. There are 813 mi between Des Moines and Charlotte. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Des Moines to Charlotte round-trip?

    Flying on American Airlines is currently your cheapest option to Charlotte, with prices starting at $337. American Airlines is priced at 29% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Des Moines to Charlotte?

    Looking at all options, your cheapest flight can be booked for $165. While the most popular route (Des Moines - Charlotte Douglas) can be booked for $231 on average, our data indicates $865 when flying from Des Moines to Charlotte.

  • Can I find deals for flights from Des Moines to Charlotte that include hotel bookings?

    Yes. In addition to deals on Des Moines to Charlotte flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Charlotte?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Charlotte.

  • Can I find deals for business class flights from Des Moines to Charlotte?

    Yes. Cheapflights offers flight deals from Des Moines to Charlotte by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Charlotte?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $374). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $912). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Rock Hill
Gastonia
Salisbury
Hickory
Morganton
Mooresville
Huntersville
Matthews
Boone
Lancaster
Shelby
Kannapolis
Gaffney
Fort Mill
Statesville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Des Moines to Charlotte

Discover the top airline that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$337Average$446FlexibilityNo cancel feeOn-time71%

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