$89+ Cheap flights from Des Moines to Charlotte (DSM - CLT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Apr 3 — Apr 101
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in April or February, booked 56 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday
Cheap flight deals from Des Moines to Charlotte
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to CharlotteExplore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 4, 2026.
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- CLT
1 stop5h 00m
Southwest
Sun 4/194:50 pm
CLT
- DSM
1 stop6h 30m
Southwest
Deal found 2/27![Southwest logo]()
$211
This CheapOair deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:20 pm
DSM
- CLT
1 stop25h 32m
Frontier
Sun 5/107:49 pm
CLT
- DSM
1 stop18h 40m
Frontier
Deal found 2/28![Frontier logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:15 am
DSM
- CLT
1 stop21h 45m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:23 pm
DSM
- CLT
1 stop10h 15m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:03 pm
DSM
- CLT
1 stop11h 03m
American Airlines
Tue 4/2811:22 am
CLT
- DSM
Nonstop2h 30m
American Airlines
Deal found 2/28![American Airlines logo]()
$241
This CheapOair deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- CLT
1 stop25h 52m
Frontier
Sun 4/196:18 pm
CLT
- DSM
1 stop19h 51m
Frontier
Deal found 2/28![Frontier logo]()
$247
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:40 am
DSM
- CLT
1 stop9h 02m
American Airlines
Fri 3/278:26 pm
CLT
- DSM
Nonstop2h 33m
American Airlines
Deal found 3/1![American Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:55 am
DSM
- CLT
2 stops26h 00m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
- CLT
1 stop23h 40m
Multiple Airlines
Wed 4/299:54 pm
CLT
- DSM
1 stop25h 12m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/223:59 pm
DSM
- CLT
2 stops17h 12m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$275
Best flights from Des Moines to CharlotteDiscover carefully curated flight deals from Des Moines to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
Discover carefully curated flight deals from Des Moines to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 4, 2026.
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:35 am
DSM
- CLT
1 stop5h 00m
Southwest
Sun 4/197:00 am
CLT
- DSM
1 stop5h 25m
Southwest
Deal found 3/1![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:30 am
DSM
- CLT
2 stops10h 41m
United Airlines
Tue 5/58:05 am
CLT
- DSM
1 stop7h 19m
United Airlines
Deal found 2/27![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:05 am
DSM
- CLT
Nonstop2h 25m
American Airlines
Sun 4/198:46 pm
CLT
- DSM
Nonstop2h 32m
American Airlines
Deal found 2/27![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:15 pm
DSM
- CLT
1 stop4h 40m
Southwest
Wed 4/2211:20 am
CLT
- DSM
2 stops10h 55m
Southwest
Deal found 3/1![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:35 am
DSM
- CLT
2 stops12h 05m
Southwest
Thu 4/96:15 am
CLT
- DSM
2 stops7h 55m
Southwest
Deal found 2/27![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:10 pm
DSM
- CLT
2 stops9h 47m
United Airlines
Sun 5/36:00 am
CLT
- DSM
2 stops9h 24m
United Airlines
Deal found 3/2![United Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:20 pm
DSM
- CLT
1 stop4h 40m
Southwest
Fri 5/227:00 pm
CLT
- DSM
1 stop5h 05m
Southwest
Deal found 2/28![Southwest logo]()
$404
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:20 am
DSM
- CLT
2 stops8h 10m
Southwest
Wed 4/291:45 pm
CLT
- DSM
2 stops9h 25m
Southwest
Deal found 3/2![Southwest logo]()
$411
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:25 am
DSM
- CLT
2 stops11h 55m
Southwest
Mon 5/187:00 pm
CLT
- DSM
1 stop5h 05m
Southwest
Deal found 2/27![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:25 am
DSM
- CLT
2 stops11h 55m
Southwest
Wed 5/2711:20 am
CLT
- DSM
2 stops10h 55m
Southwest
Deal found 2/28![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:25 am
DSM
- CLT
2 stops11h 55m
Southwest
Sat 4/258:10 am
CLT
- DSM
2 stops13h 45m
Southwest
Deal found 3/3![Southwest logo]()
$430
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:35 am
DSM
- CLT
2 stops12h 50m
Southwest
Tue 3/3110:55 am
CLT
- DSM
2 stops10h 55m
Southwest
Deal found 3/1![Southwest logo]()
$436
Last-minute flights from Des Moines to CharlotteDiscover last-minute flight deals from Des Moines to Charlotte. Data last updated March 4, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Charlotte. Data last updated March 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:15 am
DSM
- CLT
1 stop21h 45m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/223:59 pm
DSM
- CLT
2 stops17h 12m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:55 am
DSM
- CLT
2 stops26h 00m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:23 pm
DSM
- CLT
1 stop10h 15m
Multiple Airlines
Wed 3/259:00 pm
CLT
- DSM
1 stop17h 29m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$236
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:40 am
DSM
- CLT
1 stop9h 02m
American Airlines
Fri 3/278:26 pm
CLT
- DSM
Nonstop2h 33m
American Airlines
Deal found 3/1![American Airlines logo]()
$257
This CheapOair deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- CLT
1 stop25h 52m
Frontier
Sun 4/196:18 pm
CLT
- DSM
1 stop19h 51m
Frontier
Deal found 2/28![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- CLT
1 stop5h 00m
Southwest
Sun 4/194:50 pm
CLT
- DSM
1 stop6h 30m
Southwest
Deal found 2/27![Southwest logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:30 am
DSM
- CLT
1 stop23h 40m
Multiple Airlines
Wed 4/299:54 pm
CLT
- DSM
1 stop25h 12m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:03 pm
DSM
- CLT
1 stop11h 03m
American Airlines
Tue 4/2811:22 am
CLT
- DSM
Nonstop2h 30m
American Airlines
Deal found 2/28![American Airlines logo]()
$241
One-way flights from Des Moines to CharlotteSearch for one-way flight options from Des Moines to Charlotte. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
Search for one-way flight options from Des Moines to Charlotte. Find affordable one-way fares based on user searches. Data last updated March 4, 2026.
This Trip.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
DSM
- CLT
1 stop25h 52m
Frontier
Deal found 2/28![Frontier logo]()
$89
This CheapOair deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
DSM
- CLT
1 stop25h 52m
Frontier
Deal found 3/2![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:00 am
DSM
- CLT
1 stop20h 03m
Frontier
Deal found 3/3![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/314:41 pm
DSM
- CLT
1 stop15h 05m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$110
This CheapOair deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- CLT
1 stop25h 52m
Frontier
Deal found 2/27![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:41 pm
DSM
- CLT
1 stop15h 05m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$116
This Frontier deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:56 pm
DSM
- CLT
1 stop12h 02m
Frontier
Deal found 2/27![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:30 am
DSM
- CLT
1 stop22h 28m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
- CLT
1 stop21h 31m
Frontier
Deal found 3/2![Frontier logo]()
$125
This CheapOair deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:21 pm
DSM
- CLT
1 stop21h 27m
Frontier
Deal found 2/27![Frontier logo]()
$127
Find flight deals from Des Moines to Charlotte
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (Southwest) |
One-way from | $89 (Trip.com) |
Popular in | December |
Cheapest in | April |
Average price | $473 |
Good round-trip deal | $383 or less |
Good one-way deal | $243 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Sat 4/11
5:35 am-11:35 am
1 stop5h 00m
Charlotte Douglas
Sun 4/19
7:00 am-11:25 am
1 stop5h 25m
$369
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Fri 5/1
5:30 am-5:11 pm
2 stops10h 41m
Charlotte Douglas
Tue 5/5
8:05 am-2:24 pm
1 stop7h 19m
$370
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Wed 4/15
3:15 pm-8:55 pm
1 stop4h 40m
Charlotte Douglas
Wed 4/22
11:20 am-9:15 pm
2 stops10h 55m
$376
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Sat 4/18
7:05 am-10:30 am
Nonstop2h 25m
Charlotte Douglas
Sun 4/19
8:46 pm-10:18 pm
Nonstop2h 32m
$381
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Thu 4/2
5:35 am-6:40 pm
2 stops12h 05m
Charlotte Douglas
Thu 4/9
6:15 am-1:10 pm
2 stops7h 55m
$387
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Mon 5/18
4:20 pm-10:00 pm
1 stop4h 40m
Charlotte Douglas
Fri 5/22
7:00 pm-11:05 pm
1 stop5h 05m
$404
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Sun 4/26
5:20 am-2:30 pm
2 stops8h 10m
Charlotte Douglas
Wed 4/29
1:45 pm-10:10 pm
2 stops9h 25m
$411
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Fri 5/15
5:25 am-6:20 pm
2 stops11h 55m
Charlotte Douglas
Mon 5/18
7:00 pm-11:05 pm
1 stop5h 05m
$415
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Fri 5/22
5:25 am-6:20 pm
2 stops11h 55m
Charlotte Douglas
Wed 5/27
11:20 am-9:15 pm
2 stops10h 55m
$417
Des MoinesCharlotte
DSM - CLT
DSMCLT
Des Moines
Fri 4/24
5:25 am-6:20 pm
2 stops11h 55m
Charlotte Douglas
Sat 4/25
8:10 am-8:55 pm
2 stops13h 45m
$430
Showing 1-10 of 24 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Charlotte
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
DSM-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Charlotte
How far ahead should I book a flight from Des Moines to Charlotte?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Charlotte. Price data was last updated on February 27, 2026.
The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 56 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Charlotte?
Currently, March is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $207). Flying from Des Moines to Charlotte in December is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to CLT?
Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 4, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Charlotte as you normally would.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated March 4, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsGaffney
Matthews
Gastonia
Salisbury
Hickory
Morganton
Mooresville
Huntersville
Boone
Rock Hill
Lancaster
Shelby
Kannapolis
Fort Mill
Statesville
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Other flights to Charlotte
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Des Moines and Charlotte flights
Browse other Des Moines and Charlotte flight options. Last updated on March 4, 2026.
Other flights from Des Moines
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Charlotte
Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$437 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$313 | Average$432 | FlexibilityNo cancel fee | On-time71% |