$142+ Cheap flights from Des Moines to Charlotte (DSM - CLT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Charlotte with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Charlotte Douglas are usually found in April or January, booked 43 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday
Cheap flight deals from Des Moines to Charlotte
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to CharlotteExplore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to Charlotte. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Sat 10/3111:37 am -
1 stop28h 22m
Deal found 9/9![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop7h 38m
Wed 10/285:37 pm -
1 stop22h 05m
Deal found 9/7![Multiple Airlines logo]()
$288
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am -
1 stop6h 30m
Sun 9/277:54 pm -
1 stop24h 39m
Deal found 9/8![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:37 pm -
1 stop24h 22m
Sat 11/78:08 pm -
1 stop24h 38m
Deal found 9/8![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
2 stops12h 46m
Sat 10/315:37 pm -
1 stop22h 22m
Deal found 9/8![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop22h 49m
Sat 10/249:29 am -
1 stop29h 30m
Deal found 9/6![Multiple Airlines logo]()
$321
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop6h 30m
Sun 9/137:54 pm -
1 stop24h 39m
Deal found 9/8![Frontier logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Tue 11/311:52 am -
2 stops27h 03m
Deal found 9/8![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
1 stop7h 40m
Tue 11/311:52 am -
2 stops27h 03m
Deal found 9/8![Multiple Airlines logo]()
$334
Best flights from Des Moines to CharlotteDiscover carefully curated flight deals from Des Moines to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to Charlotte that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:25 pm -
1 stop4h 10m
Mon 11/97:00 pm -
1 stop5h 00m
Deal found 9/8![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop5h 20m
Sun 10/186:00 am -
1 stop4h 42m
Deal found 9/6![Delta logo]()
$541
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:00 pm -
1 stop5h 10m
Tue 10/137:25 am -
1 stop5h 05m
Deal found 9/7![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 am -
1 stop4h 25m
Fri 11/68:10 am -
1 stop4h 20m
Deal found 9/6![Southwest logo]()
$437
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:10 am -
2 stops11h 30m
Tue 1/56:50 pm -
1 stop4h 10m
Deal found 9/6![Southwest logo]()
$442
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1212:45 pm -
1 stop4h 45m
Fri 1/156:05 pm -
1 stop5h 10m
Deal found 9/6![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/84:30 pm -
1 stop4h 20m
Sun 10/187:50 am -
1 stop4h 30m
Deal found 9/8![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:25 am -
2 stops12h 25m
Wed 12/236:15 pm -
2 stops6h 15m
Deal found 9/9![Southwest logo]()
$469
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:10 am -
2 stops6h 50m
Tue 10/201:10 pm -
2 stops9h 50m
Deal found 9/5![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:30 am -
2 stops9h 55m
Wed 10/2811:15 am -
2 stops10h 25m
Deal found 9/7![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:10 am -
1 stop4h 25m
Tue 10/66:55 pm -
1 stop4h 05m
Deal found 9/9![Southwest logo]()
$487
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:10 am -
2 stops11h 30m
Wed 12/237:25 pm -
1 stop5h 05m
Deal found 9/8![Southwest logo]()
$554
Last-minute flights from Des Moines to CharlotteDiscover last-minute flight deals from Des Moines to Charlotte. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Charlotte. Data last updated September 10, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop6h 30m
Sun 9/137:54 pm -
1 stop24h 39m
Deal found 9/8![Frontier logo]()
$330
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am -
1 stop6h 30m
Sun 9/277:54 pm -
1 stop24h 39m
Deal found 9/8![Frontier logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop22h 49m
Sat 10/249:29 am -
1 stop29h 30m
Deal found 9/6![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop7h 38m
Wed 10/285:37 pm -
1 stop22h 05m
Deal found 9/7![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:11 pm -
2 stops12h 46m
Sat 10/315:37 pm -
1 stop22h 22m
Deal found 9/8![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Sat 10/3111:37 am -
1 stop28h 22m
Deal found 9/9![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Tue 11/311:52 am -
2 stops27h 03m
Deal found 9/8![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Thu 11/56:05 am -
2 stops33h 31m
Deal found 9/8![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:48 pm -
2 stops16h 49m
Sat 10/315:37 pm -
1 stop22h 22m
Deal found 9/9![Multiple Airlines logo]()
$338
One-way flights from Des Moines to CharlotteSearch for one-way flight options from Des Moines to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to Charlotte. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:35 pm -
1 stop18h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$142
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:29 am -
1 stop6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$153
This Frontier deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:29 am -
1 stop6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
2 stops46h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 pm -
2 stops13h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$174
Find flight deals from Des Moines to Charlotte
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Charlotte (CLT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $187 (Kiwi.com) |
One-way from | $142 (CheapOair) |
Popular in | March |
Cheapest in | April |
Average price | $471 |
Good round-trip deal | $413 or less |
Good one-way deal | $176 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Mon 12/7
3:30 pm-9:20 pm
1 stop4h 50m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Tue 12/8
6:00 am-5:40 pm
2 stops10h 40m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$184
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Wed 11/4
3:30 pm-9:20 pm
1 stop4h 50m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$219
Quickest round-trip
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Sun 12/20
5:10 am-10:35 am
1 stop4h 25m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$275
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Wed 10/7
6:00 am-9:15 pm
1 stop14h 15m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$322
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Wed 12/9
9:30 am-8:48 pm
1 stop10h 18m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$322
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Sat 12/5
11:27 am-11:44 pm
2 stops11h 17m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$328
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Sat 10/10
6:00 am-11:56 pm
2 stops16h 56m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$328
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Mon 11/2
4:25 pm-9:35 pm
1 stop4h 10m
Charlotte Douglas
Mon 11/9
7:00 pm-11:00 pm
1 stop5h 00m
$357
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Tue 10/6
3:00 pm-9:10 pm
1 stop5h 10m
Charlotte Douglas
Tue 10/13
7:25 am-11:30 am
1 stop5h 05m
$437
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Charlotte
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Charlotte in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Charlotte flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Charlotte flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Charlotte flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Charlotte flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Charlotte flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Charlotte
Have a flexible travel schedule? Discover the best time to fly to Charlotte from Des Moines with our price prediction graph.
DSM-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Charlotte
How far ahead should I book a flight from Des Moines to Charlotte?
The price you pay for your flight from Des Moines to Charlotte may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Charlotte?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Charlotte (average of $411). Flying from Des Moines to Charlotte in March is currently the most expensive (average of $769). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to CLT?
Find hourly flight availability from Des Moines to Charlotte. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Charlotte as you normally would.
Reviews of airlines servicing Charlotte
Get insights into the airlines that provide service to Charlotte. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charlotte. Reviews last updated September 10, 2026.
See what other customers who have flown with Southwest and American Airlines from Des Moines to Charlotte have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Charlotte. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charlotte?
Book flights to Charlotte if you plan to visit one of these locationsRock Hill
Gastonia
Boone
Salisbury
Cornelius
Morganton
Mooresville
Huntersville
Matthews
Lancaster
Hickory
Shelby
Gaffney
Fort Mill
Statesville
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Explore flights to Charlotte departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
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Find flights from Des Moines to Charlotte, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Charlotte flights
Browse other Des Moines and Charlotte flight options. Last updated on September 10, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
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Top 2 airlines flying from Des Moines to Charlotte
Discover the top 2 airlines that operate flights from Des Moines to Charlotte. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$334 | Average$450 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$369 | Average$465 | FlexibilityNo cancel fee | On-time71% |