$161+ Cheap flights from Des Moines to Myrtle Beach (DSM - MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MYR
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to Myrtle BeachExplore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Des Moines to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:40 am
DSM
- MYR
1 stop4h 07m
Delta
Sun 9/611:43 am
MYR
- DSM
1 stop4h 33m
Delta
Deal found 6/8![Delta logo]()
$307
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:30 pm
DSM
- MYR
1 stop6h 38m
American Airlines
Mon 9/147:10 pm
MYR
- DSM
1 stop5h 31m
American Airlines
Deal found 6/8![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:10 am
DSM
- MYR
2 stops8h 55m
Southwest
Sun 9/69:20 am
MYR
- DSM
2 stops12h 55m
Southwest
Deal found 6/8![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:30 am
DSM
- MYR
1 stop6h 37m
Delta
Wed 8/56:00 am
MYR
- DSM
1 stop5h 43m
Delta
Deal found 6/5![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am
DSM
- MYR
2 stops6h 30m
Southwest
Mon 8/312:30 pm
MYR
- DSM
2 stops8h 40m
Southwest
Deal found 6/7![Southwest logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:59 pm
DSM
- MYR
2 stops48h 51m
Multiple Airlines
Fri 7/248:41 pm
MYR
- DSM
1 stop26h 02m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- MYR
2 stops12h 05m
Southwest
Wed 8/57:50 am
MYR
- DSM
1 stop5h 00m
Southwest
Deal found 6/5![Southwest logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
DSM
- MYR
1 stop16h 10m
Multiple Airlines
Fri 7/174:02 pm
MYR
- DSM
2 stops41h 31m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 am
DSM
- MYR
1 stop6h 22m
American Airlines
Tue 7/76:51 am
MYR
- DSM
1 stop7h 05m
American Airlines
Deal found 6/7![American Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1311:00 am
DSM
- MYR
1 stop5h 25m
American Airlines
Sat 9/198:08 am
MYR
- DSM
1 stop4h 56m
American Airlines
Deal found 6/8![American Airlines logo]()
$382
Best flights from Des Moines to Myrtle BeachDiscover carefully curated flight deals from Des Moines to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Des Moines to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:45 pm
DSM
- MYR
1 stop5h 05m
Southwest
Mon 7/137:25 am
MYR
- DSM
1 stop5h 05m
Southwest
Deal found 6/8![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:37 pm
DSM
- MYR
1 stop4h 18m
Delta
Tue 7/2811:42 am
MYR
- DSM
1 stop7h 10m
Delta
Deal found 6/4![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1311:00 am
DSM
- MYR
1 stop5h 25m
American Airlines
Sat 9/198:08 am
MYR
- DSM
1 stop4h 56m
American Airlines
Deal found 6/4![American Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:10 am
DSM
- MYR
2 stops10h 35m
Southwest
Fri 7/107:15 pm
MYR
- DSM
1 stop5h 20m
Southwest
Deal found 6/5![Southwest logo]()
$384
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:10 am
DSM
- MYR
1 stop10h 30m
Southwest
Fri 8/71:55 pm
MYR
- DSM
2 stops9h 15m
Southwest
Deal found 6/8![Southwest logo]()
$400
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
DSM
- MYR
1 stop5h 10m
Southwest
Fri 7/177:15 pm
MYR
- DSM
1 stop5h 20m
Southwest
Deal found 6/5![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am
DSM
- MYR
1 stop4h 35m
Southwest
Tue 9/227:50 am
MYR
- DSM
1 stop5h 00m
Southwest
Deal found 6/7![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
DSM
- MYR
2 stops8h 55m
Southwest
Fri 9/48:10 am
MYR
- DSM
1 stop4h 15m
Southwest
Deal found 6/7![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am
DSM
- MYR
2 stops6h 30m
Southwest
Tue 9/297:50 am
MYR
- DSM
1 stop5h 00m
Southwest
Deal found 6/6![Southwest logo]()
$412
Last-minute flights from Des Moines to Myrtle BeachDiscover last-minute flight deals from Des Moines to Myrtle Beach. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Myrtle Beach. Data last updated June 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:37 pm
DSM
- MYR
1 stop7h 09m
American Airlines
Sat 7/41:17 pm
MYR
- DSM
1 stop5h 26m
American Airlines
Deal found 6/8![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:00 am
DSM
- MYR
1 stop6h 22m
American Airlines
Tue 7/76:51 am
MYR
- DSM
1 stop7h 05m
American Airlines
Deal found 6/7![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- MYR
2 stops12h 05m
Southwest
Mon 7/132:00 pm
MYR
- DSM
2 stops9h 25m
Southwest
Deal found 6/8![Southwest logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:59 pm
DSM
- MYR
2 stops16h 51m
Multiple Airlines
Thu 7/1612:01 pm
MYR
- DSM
1 stop28h 49m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
DSM
- MYR
1 stop16h 10m
Multiple Airlines
Fri 7/174:02 pm
MYR
- DSM
2 stops41h 31m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:59 pm
DSM
- MYR
2 stops48h 51m
Multiple Airlines
Fri 7/248:41 pm
MYR
- DSM
1 stop26h 02m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:30 am
DSM
- MYR
1 stop6h 37m
Delta
Wed 8/56:00 am
MYR
- DSM
1 stop5h 43m
Delta
Deal found 6/5![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- MYR
2 stops12h 05m
Southwest
Wed 8/57:50 am
MYR
- DSM
1 stop5h 00m
Southwest
Deal found 6/5![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:04 am
DSM
- MYR
1 stop7h 27m
American Airlines
Sun 8/28:44 pm
MYR
- DSM
1 stop4h 25m
American Airlines
Deal found 6/9![American Airlines logo]()
$399
One-way flights from Des Moines to Myrtle BeachSearch for one-way flight options from Des Moines to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Des Moines to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:08 pm
DSM
- MYR
2 stops46h 05m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- MYR
1 stop15h 51m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$164
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:35 am
DSM
- MYR
1 stop4h 09m
Delta
Deal found 6/8![Delta logo]()
$176
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:10 am
DSM
- MYR
2 stops10h 35m
Southwest
Deal found 6/6![Southwest logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/53:59 pm
DSM
- MYR
2 stops48h 51m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:53 am
DSM
- MYR
2 stops7h 32m
American Airlines
Deal found 6/6![American Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:00 am
DSM
- MYR
1 stop28h 14m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:30 pm
DSM
- MYR
2 stops38h 25m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$211
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:00 am
DSM
- MYR
1 stop6h 22m
American Airlines
Deal found 6/6![American Airlines logo]()
$214
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:30 am
DSM
- MYR
2 stops8h 02m
American Airlines
Deal found 6/8![American Airlines logo]()
$219
Find flight deals from Des Moines to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $307 (Delta) |
One-way from | $161 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $430 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Des Moines to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Tue 7/7
3:45 pm-9:50 pm
1 stop5h 05m
Myrtle Beach Intl
Mon 7/13
7:25 am-11:30 am
1 stop5h 05m
$379
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Sat 7/4
5:10 am-4:45 pm
2 stops10h 35m
Myrtle Beach Intl
Fri 7/10
7:15 pm-11:35 pm
1 stop5h 20m
$384
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Fri 7/24
6:37 pm-11:55 pm
1 stop4h 18m
Myrtle Beach Intl
Tue 7/28
11:42 am-5:52 pm
1 stop7h 10m
$389
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Tue 8/4
6:10 am-5:40 pm
1 stop10h 30m
Myrtle Beach Intl
Fri 8/7
1:55 pm-10:10 pm
2 stops9h 15m
$400
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Mon 7/13
4:40 pm-10:50 pm
1 stop5h 10m
Myrtle Beach Intl
Fri 7/17
7:15 pm-11:35 pm
1 stop5h 20m
$407
Quickest round-trip
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Sat 9/19
5:30 am-11:05 am
1 stop4h 35m
Myrtle Beach Intl
Tue 9/22
7:50 am-11:50 am
1 stop5h 00m
$407
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Wed 9/2
6:10 am-4:05 pm
2 stops8h 55m
Myrtle Beach Intl
Fri 9/4
8:10 am-11:25 am
1 stop4h 15m
$412
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Thu 9/24
5:40 am-1:10 pm
2 stops6h 30m
Myrtle Beach Intl
Tue 9/29
7:50 am-11:50 am
1 stop5h 00m
$412
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Sun 9/13
11:00 am-5:25 pm
1 stop5h 25m
Myrtle Beach Intl
Sat 9/19
8:08 am-12:04 pm
1 stop4h 56m
$414
Cheapest one-way
Des MoinesMyrtle Beach
DSM - MYR
DSMMYR
Des Moines
Sat 7/4
5:50 am-3:04 pm
1 stop8h 14m
$176
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Myrtle Beach in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Des Moines with our price prediction graph.
DSM-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Myrtle Beach
What is the cheapest month to book a flight from Des Moines to Myrtle Beach?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Myrtle Beach (average of $291). Flying from Des Moines to Myrtle Beach in July is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Myrtle Beach?
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated June 9, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Des Moines to Myrtle Beach have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Crew
8.6
Overall
7.9
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Surfside Beach
Pawleys Island
Little River
Garden City Beach
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Top 3 airlines flying from Des Moines to Myrtle Beach
Discover the top 3 airlines that operate flights from Des Moines to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$406 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$302 | Average$396 | FlexibilityNo cancel fee | On-timeN/A |