Cheap flights from Des Moines (DSM) to South Carolina (SC)

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How to find the cheapest flight from
Des Moines (DSM) to South Carolina

All the information you need to plan the best DSM to CHS flight in 2021: compare Des Moines to South Carolina flight prices with the expected peak season, weather and rainfall in South Carolina.
How far in advance should I book a flight from Des Moines to South Carolina?

To save up to 21% on this flight, we recommend booking at least 16 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Des Moines to South Carolina from $234 1-2 weeks out and tickets from $306 for flights departing within the next 72 hours.

What is the cheapest month to fly from Des Moines to South Carolina?

The best pricing can be found in the month of August. Prices to South Carolina from Des Moines average $324. You can even find prices in August for less than $324, as users have found deals to South Carolina from as low as $124. The month of December appears to be one of the more expensive times to travel to South Carolina from Des Moines. Flying in the targeted month can save you up to 64%.

Cheap flights from Des Moines to South Carolina in May, June 2021

The best prices found for DSM to South Carolina flights for May, June
30 Jun - 7 Jul
$312pp
DSM
Des Moines
American Airlines
 
1 STOP
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
American Airlines
 
1 STOP
DSM
Des Moines
22 Jun - 26 Jun
$313pp
DSM
Des Moines
Multiple Airlines
 
1 STOP
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
United Airlines
 
1 STOP
DSM
Des Moines
27 May - 3 Jun
$315pp
DSM
Des Moines
United Airlines
 
1 STOP
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
United Airlines
 
1 STOP
DSM
Des Moines

Des Moines to South Carolina 2021 flight deals

Cheap flights to South Carolina from Des Moines found for this year
18 Sep - 22 Sep
$177pp
DSM
Des Moines
Delta
 
1 STOP
CHS
Charleston
CHS
Charleston
Delta
 
1 STOP
DSM
Des Moines
18 Sep - 22 Sep
$181pp
DSM
Des Moines
Delta
   
2 STOPS
CHS
Charleston
CHS
Charleston
Delta
 
1 STOP
DSM
Des Moines
18 Sep - 22 Sep
$204pp
DSM
Des Moines
Multiple Airlines
   
2 STOPS
CHS
Charleston
CHS
Charleston
American Airlines
   
2 STOPS
DSM
Des Moines

Last minute flights from Des Moines to South Carolina

Late deals on round-trip flights to South Carolina from Des Moines, departing today and this week
25 May - 28 May
$374pp
DSM
Des Moines
United Airlines
 
1 STOP
CHS
Charleston
CHS
Charleston
United Airlines
 
1 STOP
DSM
Des Moines
21 May - 26 May
$404pp
DSM
Des Moines
American Airlines
 
1 STOP
CHS
Charleston
CHS
Charleston
American Airlines
 
1 STOP
DSM
Des Moines
21 May - 26 May
$408pp
DSM
Des Moines
American Airlines
 
1 STOP
CHS
Charleston
CHS
Charleston
American Airlines
   
2 STOPS
DSM
Des Moines

One-way flights to South Carolina from Des Moines

The cheapest one-way flights from Des Moines to South Carolina
6:00 am - 7:08 am
Multiple Airlines
3 Stops
24h 08m
DSM - MYR
Multiple Airlines
$214
Gotogate
9:00 am - 6:54 pm
Delta
2 Stops
8h 54m
DSM - CHS
Delta
$223
Delta
6:53 am - 5:06 pm
American Airlines
2 Stops
9h 13m
DSM - GSP
American Airlines

Related info for your journey

Useful info, stats and facts about <span class="emphasized">Des Moines</span> to <span class="emphasized">South Carolina</span> flights.

Flight FAQs

From Des Moines to South Carolina

Are flight prices decreasing from Des Moines to South Carolina due to COVID-19 (coronavirus)?

At this time, Cheapflights has noticed price decreases for many domestic flights due to COVID-19. Travel is not necessarily recommended at this time, and flights may be prone to cancellation: please check with local authorities in both Des Moines and South Carolina for travel alerts, and be sure to review the airline's cancellation policy and travel advisories before booking. For more information, please view our post on what to know about COVID-19 (coronavirus) and travel.

Which airlines flying from Des Moines to South Carolina have flexible cancellations due to COVID-19?

American Airlines, Delta, and United Airlines are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

What airport do you fly from for flights from Des Moines to South Carolina?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South Carolina.

Can I find flights from Des Moines to South Carolina for under $200 on Cheapflights?

Yes, there are multiple flights from Des Moines to South Carolina for under $200. The cheapest flight booked recently is on Delta for just $177, but on average you can expect to pay $215.

Are there nonstop flights from Des Moines to South Carolina for under $200 on Cheapflights?

There are no nonstop flights from Des Moines to South Carolina, but Cheapflights can provide you with all the information you need to find the fastest route with the fewest stops.

Are there last-minute flights available from Des Moines to South Carolina for under $400?

There are currently 20+ open flights from Des Moines to South Carolina within the next 7 days for less than $400.

What are the most popular airlines that fly from Des Moines to South Carolina?

When booking a flight from Des Moines to South Carolina, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What are the most popular routes from Des Moines to South Carolina?

The most popular flight routes from Des Moines to South Carolina are Des Moines - Myrtle Beach Metropolitan Area, Des Moines - Charleston and Des Moines - Hilton Head Island.

What are the cheapest Flights from Des Moines to South Carolina?

Looking at all options, your cheapest flight can be booked for $129. While the most popular route (Des Moines - Myrtle Beach Metropolitan Area) can be booked for $214 on average our data indicates $303 when flying from Des Moines to South Carolina

How long is the flight from Des Moines to South Carolina?

For as low as $354, American Airlines can have you in South Carolina from Des Moines in 3h 55m. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to South Carolina round-trip?

Cheapflights users have booked flights from Des Moines to South Carolina round-trip from $177. Another airline that can offer you cheap pricing is American Airlines.

What are the cheapest airlines to fly from Des Moines to South Carolina one-way?

The cheapest airlines for a one-way flight from Des Moines to South Carolina are American Airlines ($123), Delta ($129), and United Airlines ($168).

Destination points for flights from Des Moines to South Carolina

Select to see more specific information for flights from Des Moines to all places in South Carolina.

Destination information for South Carolina

Things to know before you go - useful duration and weather info for your trip from Des Moines to South Carolina.

Airports servicing Des Moines

Airports servicing

Charleston (CHS)
Florence (FLO)
Greenville (GSP)
Hilton Head Island (HHH)
Myrtle Beach (MYR)

Top 3 airlines flying from Des Moines to South Carolina

The chart below displays the airlines Cheapflights users traveling from Des Moines to South Carolina choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.
Airline Cheapest Average Flexibility On-time COVID-19 safety
United Airlines
$132 $311 No cancel fee 69%
Delta
$140 $358 No cancel fee N/A
American Airlines
$152 $394 No cancel fee 71%
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