Cheap flights from Des Moines (DSM) to South Carolina (SC)

Flight FAQs

From Des Moines to South Carolina

Are flight prices decreasing from Des Moines to South Carolina due to COVID-19 (coronavirus)?

At this time, Cheapflights has noticed price decreases for many domestic flights due to COVID-19. Travel is not necessarily recommended at this time, and flights may be prone to cancellation: please check with local authorities in both Des Moines and South Carolina for travel alerts, and be sure to review the airline's cancellation policy and travel advisories before booking. For more information, please view our post on what to know about COVID-19 (coronavirus) and travel.

Which airlines flying from Des Moines to South Carolina have flexible cancellations due to COVID-19?

American Airlines, Delta, and United Airlines are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

What airport do you fly from for flights from Des Moines to South Carolina?

Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to South Carolina.

Can I find flights from Des Moines to South Carolina for under $200 on Cheapflights?

Yes, there are multiple flights from Des Moines to South Carolina for under $200. The cheapest flight booked recently is on Delta for just $177, but on average you can expect to pay $215.

Are there nonstop flights from Des Moines to South Carolina for under $200 on Cheapflights?

There are no nonstop flights from Des Moines to South Carolina, but Cheapflights can provide you with all the information you need to find the fastest route with the fewest stops.

Are there last-minute flights available from Des Moines to South Carolina for under $400?

There are currently 20+ open flights from Des Moines to South Carolina within the next 7 days for less than $400.

What are the most popular airlines that fly from Des Moines to South Carolina?

When booking a flight from Des Moines to South Carolina, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What are the most popular routes from Des Moines to South Carolina?

The most popular flight routes from Des Moines to South Carolina are Des Moines - Myrtle Beach Metropolitan Area, Des Moines - Charleston and Des Moines - Hilton Head Island.

What are the cheapest Flights from Des Moines to South Carolina?

Looking at all options, your cheapest flight can be booked for $129. While the most popular route (Des Moines - Myrtle Beach Metropolitan Area) can be booked for $214 on average our data indicates $303 when flying from Des Moines to South Carolina

How long is the flight from Des Moines to South Carolina?

For as low as $354, American Airlines can have you in South Carolina from Des Moines in 3h 55m. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to South Carolina round-trip?

Cheapflights users have booked flights from Des Moines to South Carolina round-trip from $177. Another airline that can offer you cheap pricing is American Airlines.

What are the cheapest airlines to fly from Des Moines to South Carolina one-way?

The cheapest airlines for a one-way flight from Des Moines to South Carolina are American Airlines ($123), Delta ($129), and United Airlines ($168).