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Cheap flights from Des Moines (DSM) to South Carolina (SC)

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How to find the cheapest flight from
Des Moines (DSM) to South Carolina

How far in advance should I book a flight from Des Moines to South Carolina?

To save up to 21% on this flight, we recommend booking at least 16 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Des Moines to South Carolina from $234 1-2 weeks out and tickets from $306 for flights departing within the next 72 hours.

What is the cheapest month to fly from Des Moines to South Carolina?

The best pricing can be found in the month of August. Prices to South Carolina from Des Moines average $324. You can even find prices in August for less than $324, as users have found deals to South Carolina from as low as $124. The month of December appears to be one of the more expensive times to travel to South Carolina from Des Moines. Flying in the targeted month can save you up to 64%.

Cheap flights from Des Moines to South Carolina in January, February 2021

24 Feb - 1 Mar
$203pp
DSM
Des Moines
United Airlines
 
1 STOP
GSP
Greenville
GSP
Greenville
United Airlines
 
1 STOP
DSM
Des Moines
24 Feb - 1 Mar
$207pp
DSM
Des Moines
United Airlines
   
2 STOPS
GSP
Greenville
GSP
Greenville
United Airlines
 
1 STOP
DSM
Des Moines
24 Feb - 1 Mar
$211pp
DSM
Des Moines
United Airlines
   
2 STOPS
GSP
Greenville
GSP
Greenville
United Airlines
   
2 STOPS
DSM
Des Moines

Des Moines to South Carolina 2021 flight deals

22 Apr - 26 Apr
$203pp
DSM
Des Moines
United Airlines
 
1 STOP
CHS
Charleston AFB-Municipal
CHS
Charleston AFB-Municipal
United Airlines
 
1 STOP
DSM
Des Moines
24 Feb - 1 Mar
$203pp
DSM
Des Moines
United Airlines
 
1 STOP
GSP
Greenville
GSP
Greenville
United Airlines
 
1 STOP
DSM
Des Moines
22 Apr - 26 Apr
$207pp
DSM
Des Moines
United Airlines
   
2 STOPS
CHS
Charleston AFB-Municipal
CHS
Charleston AFB-Municipal
United Airlines
 
1 STOP
DSM
Des Moines

Last minute flights from Des Moines to South Carolina

7 Feb - 14 Feb
$235pp
DSM
Des Moines
Multiple Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Multiple Airlines
   
2 STOPS
DSM
Des Moines
7 Feb - 11 Feb
$254pp
DSM
Des Moines
Multiple Airlines
   
2 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Multiple Airlines
   
2 STOPS
DSM
Des Moines
7 Feb - 14 Feb
$281pp
DSM
Des Moines
Multiple Airlines
     
3 STOPS
MYR
Myrtle Beach Metropolitan Area
MYR
Myrtle Beach Metropolitan Area
Multiple Airlines
   
2 STOPS
DSM
Des Moines

One-way flights to South Carolina from Des Moines

12:29 pm - 5:19 am
American Airlines
2 Stops
15h 50m
DSM - GSP
American Airlines
1:10 am - 9:54 am
Delta
2 Stops
7h 44m
DSM - CAE
Delta
$246
Delta
1:35 pm - 8:56 am
United Airlines
3 Stops
18h 21m
DSM - GSP
United Airlines
$251
United

Related info for your journey

Flight FAQs

From Des Moines to South Carolina

Are flight prices decreasing from Des Moines to South Carolina due to COVID-19 (coronavirus)?

At this time, Cheapflights has noticed price decreases for many domestic flights due to COVID-19. Travel is not necessarily recommended at this time, and flights may be prone to cancellation: please check with local authorities in both Des Moines and South Carolina for travel alerts, and be sure to review the airline's cancellation policy and travel advisories before booking. For more information, please view our post on what to know about COVID-19 (coronavirus) and travel.

What safety measures are being taken by airlines flying from Des Moines to South Carolina to control the spread of COVID-19?

Delta is one of the many airlines that have implemented additional safety measures to control the spread of COVID-19. New policies for travelers booking flights from Des Moines to South Carolina include masks being provided and required on board, daily cleaning and sanitization, use of HEPA filters, pre-flight testing for antibodies and symptoms, and socially distanced seating (for a limited time). Keep in mind that policies will vary by airline.

Which airlines flying from Des Moines to South Carolina have flexible cancellations due to COVID-19?

American Airlines, Delta, and United Airlines are some of the carriers that may have flexible cancellation policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

Can I find flights from Des Moines to South Carolina for under $300 on Cheapflights?

Yes, there are multiple flights from Des Moines to South Carolina for under $300. The cheapest flight booked recently is on United Airlines for just $203, but on average you can expect to pay $228.

Are there nonstop flights from Des Moines to South Carolina for under $200 on Cheapflights?

There are no nonstop flights from Des Moines to South Carolina, but Cheapflights can provide you with all the information you need to find the fastest route with the fewest stops.

Are there last-minute flights available from Des Moines to South Carolina for under $300?

There are currently 17+ open flights from Des Moines to South Carolina within the next 7 days for less than $300.

What are the most popular airlines that fly from Des Moines to South Carolina?

When booking a flight from Des Moines to South Carolina, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What are the most popular routes from Des Moines to South Carolina?

The most popular flight routes from Des Moines to South Carolina are Des Moines - Myrtle Beach Metropolitan Area, Des Moines - Charleston AFB-Municipal and Des Moines - Columbia Metropolitan.

What are the cheapest Flights from Des Moines to South Carolina?

Looking at all options, your cheapest flight can be booked for $129. While the most popular route (Des Moines - Myrtle Beach Metropolitan Area) can be booked for $228 on average our data indicates $308 when flying from Des Moines to South Carolina

How long is the flight from Des Moines to South Carolina?

For as low as $249, Delta can have you in South Carolina from Des Moines in 3h 43m. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to South Carolina round-trip?

Cheapflights users have booked flights from Des Moines to South Carolina round-trip from $203. Other airlines that can offer you cheap pricing are American Airlines, from $235, and Delta, from $249.

What are the cheapest airlines to fly from Des Moines to South Carolina one-way?

The cheapest airlines for a one-way flight from Des Moines to South Carolina are United Airlines ($107), American Airlines ($113), and Delta ($129).

Arrival points for flights from Des Moines to South Carolina

Destination information for South Carolina

Airports servicing Des Moines

Airports servicing

Charleston (CHS)
Florence (FLO)
Greenville (GSP)
Hilton Head Island (HHH)
Myrtle Beach (MYR)

Top 3 airlines flying from Des Moines to South Carolina

Airline Cheapest Average Flexibility On-time COVID-19 safety
United Airlines
$132 $311 No cancel fee 69%
Delta
$140 $358 No cancel fee N/A
American Airlines
$152 $394 No cancel fee 71%
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