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$396+ Cheap flights from La Crosse to Charleston (LSE - CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from La Crosse to Charleston

Cheapest flights from La Crosse to Charleston
Explore the most affordable flight options available from La Crosse to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:52 am
LSE
-
CHS
2 stops10h 06m
American Airlines
Tue 6/3012:25 pm
CHS
-
LSE
1 stop5h 37m
American Airlines
Deal found 4/19$396
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:19 pm
LSE
-
CHS
1 stop4h 56m
American Airlines
Wed 10/148:01 pm
CHS
-
LSE
1 stop4h 18m
American Airlines
Deal found 4/20$499
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:36 pm
LSE
-
CHS
1 stop16h 13m
American Airlines
Tue 5/127:07 am
CHS
-
LSE
1 stop17h 47m
American Airlines
Deal found 4/23$527

Find flight deals from La Crosse to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$396
(American Airlines)
Provider with most accurate pricing for La Crosse-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for La Crosse-Charleston flights.
Search Deals
From La Crosse to Charleston
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Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from La Crosse to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Fri 6/26

11:52 am-10:58 pm

2 stops10h 06m

Charleston

Tue 6/30

12:25 pm-5:02 pm

1 stop5h 37m

$396
Quickest round-trip

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Wed 10/7

6:19 pm-12:15 am

1 stop4h 56m

Charleston

Wed 10/14

8:01 pm-11:19 pm

1 stop4h 18m

$499

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Fri 5/8

6:36 pm-11:49 am

1 stop16h 13m

Charleston

Tue 5/12

7:07 am-11:54 pm

1 stop17h 47m

$527

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/19

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on La Crosse-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on La Crosse-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from La Crosse to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated April 23, 2026.
Read through reviews of airlines operating flights from La Crosse to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,659 reviews

Food

6.4

Boarding

7.5

Overall

7.1

Comfort

7.2

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,659 reviews
American Airlines
7.1
Good
11,659 reviews

Food

6.4

Boarding

7.5

Overall

7.1

Comfort

7.2

Crew

7.9

Entertainment

6.9

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to Charleston?

    American Airlines can get you from La Crosse to Charleston in just under 10h 06m. Your travel time can differ by up to . The distance from La Crosse to Charleston is about 970 mi.

  • Can I find deals for flights from La Crosse to Charleston that include hotel bookings?

    Yes. In addition to deals on La Crosse to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Charleston.

  • Can I find deals for business class flights from La Crosse to Charleston?

    Yes. Cheapflights offers flight deals from La Crosse to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from La Crosse to Charleston

Discover the top airline that operate flights from La Crosse to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$308Average$608FlexibilityNo cancel feeOn-time71%

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