$191+ Cheap flights from La Crosse to Charleston (LSE - CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from La Crosse to CharlestonExplore the most affordable flight options available from La Crosse to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from La Crosse to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:26 pm
LSE
- CHS
1 stop5h 45m
American Airlines
Sat 10/37:18 am
CHS
- LSE
1 stop5h 04m
American Airlines
Deal found 7/27![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:54 am
LSE
- CHS
2 stops9h 56m
American Airlines
Wed 10/77:16 am
CHS
- LSE
1 stop5h 37m
American Airlines
Deal found 7/25![American Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:01 pm
LSE
- CHS
1 stop6h 19m
American Airlines
Sun 8/2312:23 pm
CHS
- LSE
1 stop5h 33m
American Airlines
Deal found 7/24![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:54 am
LSE
- CHS
1 stop6h 21m
American Airlines
Tue 10/67:16 am
CHS
- LSE
1 stop5h 37m
American Airlines
Deal found 7/25![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:02 pm
LSE
- CHS
1 stop5h 40m
American Airlines
Tue 10/67:16 am
CHS
- LSE
1 stop5h 37m
American Airlines
Deal found 7/25![American Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:02 pm
LSE
- CHS
1 stop5h 40m
American Airlines
Wed 10/75:05 am
CHS
- LSE
2 stops7h 48m
American Airlines
Deal found 7/25![American Airlines logo]()
$412
Best flights from La Crosse to CharlestonDiscover carefully curated flight deals from La Crosse to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from La Crosse to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:26 pm
LSE
- CHS
1 stop5h 45m
American Airlines
Sat 10/37:18 am
CHS
- LSE
1 stop5h 04m
American Airlines
Deal found 7/27![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:02 pm
LSE
- CHS
1 stop5h 40m
American Airlines
Sat 10/37:46 pm
CHS
- LSE
1 stop5h 34m
American Airlines
Deal found 7/25![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:01 pm
LSE
- CHS
1 stop6h 19m
American Airlines
Sun 8/235:05 am
CHS
- LSE
2 stops7h 18m
American Airlines
Deal found 7/24![American Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:01 pm
LSE
- CHS
1 stop6h 19m
American Airlines
Sun 8/235:05 am
CHS
- LSE
2 stops7h 18m
American Airlines
Deal found 7/24![American Airlines logo]()
$491
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:26 pm
LSE
- CHS
1 stop5h 45m
American Airlines
Sat 10/34:08 pm
CHS
- LSE
2 stops9h 12m
American Airlines
Deal found 7/25![American Airlines logo]()
$493
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:54 am
LSE
- CHS
1 stop6h 21m
American Airlines
Mon 10/57:16 am
CHS
- LSE
1 stop5h 37m
American Airlines
Deal found 7/25![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:54 am
LSE
- CHS
2 stops9h 56m
American Airlines
Mon 10/58:08 pm
CHS
- LSE
2 stops16h 45m
American Airlines
Deal found 7/25![American Airlines logo]()
$617
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:54 am
LSE
- CHS
1 stop6h 21m
American Airlines
Fri 10/97:16 am
CHS
- LSE
1 stop5h 37m
American Airlines
Deal found 7/25![American Airlines logo]()
$619
Last-minute flights from La Crosse to CharlestonDiscover last-minute flight deals from La Crosse to Charleston. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Charleston. Data last updated July 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:02 am
LSE
- CHS
1 stop4h 31m
American Airlines
Thu 8/137:00 am
CHS
- LSE
1 stop18h 22m
American Airlines
Deal found 7/25![American Airlines logo]()
$1,302
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:01 pm
LSE
- CHS
1 stop6h 19m
American Airlines
Sun 8/2312:23 pm
CHS
- LSE
1 stop5h 33m
American Airlines
Deal found 7/24![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:01 pm
LSE
- CHS
1 stop6h 19m
American Airlines
Sun 8/2312:23 pm
CHS
- LSE
1 stop5h 33m
American Airlines
Deal found 7/24![American Airlines logo]()
$485
One-way flights from La Crosse to CharlestonSearch for one-way flight options from La Crosse to Charleston. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from La Crosse to Charleston. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2310:51 am
LSE
- CHS
3 stops45h 46m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:17 pm
LSE
- CHS
2 stops19h 30m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:36 pm
LSE
- CHS
3 stops43h 02m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:26 pm
LSE
- CHS
1 stop17h 07m
American Airlines
Deal found 7/27![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:01 pm
LSE
- CHS
2 stops9h 49m
American Airlines
Deal found 7/23![American Airlines logo]()
$647
Find flight deals from La Crosse to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Kiwi.com) |
One-way from | $196 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from La Crosse to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Tue 9/29
12:26 pm-7:11 pm
1 stop5h 45m
Charleston
Sat 10/3
7:18 am-11:22 am
1 stop5h 04m
$280
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Wed 9/30
12:02 pm-6:42 pm
1 stop5h 40m
Charleston
Sat 10/3
7:46 pm-12:20 am
1 stop5h 34m
$370
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Wed 8/19
12:01 pm-7:20 pm
1 stop6h 19m
Charleston
Sun 8/23
5:05 am-11:23 am
2 stops7h 18m
$397
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Thu 8/20
12:01 pm-7:20 pm
1 stop6h 19m
Charleston
Sun 8/23
5:05 am-11:23 am
2 stops7h 18m
$491
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Thu 10/1
12:26 pm-7:11 pm
1 stop5h 45m
Charleston
Sat 10/3
4:08 pm-12:20 am
2 stops9h 12m
$493
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Fri 10/2
5:54 am-1:15 pm
1 stop6h 21m
Charleston
Mon 10/5
7:16 am-11:53 am
1 stop5h 37m
$562
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Tue 9/29
5:54 am-4:50 pm
2 stops9h 56m
Charleston
Mon 10/5
8:08 pm-11:53 am
2 stops16h 45m
$617
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Tue 9/29
5:54 am-1:15 pm
1 stop6h 21m
Charleston
Fri 10/9
7:16 am-11:53 am
1 stop5h 37m
$619
Cheapest one-way
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Sun 8/23
10:51 am-9:37 am
3 stops45h 46m
$191
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Sun 10/25
6:17 pm-2:47 pm
2 stops19h 30m
$196
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on La Crosse-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from La Crosse with our price prediction graph.
LSE-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated July 28, 2026.
Read through reviews of airlines operating flights from La Crosse to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Food
6.4
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Overall
7.1
Food
6.4
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for La Crosse to Charleston
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Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from La Crosse to Charleston by cabin class
Find flights from La Crosse to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
La Crosse and Charleston flights
Browse other La Crosse and Charleston flight options. Last updated on July 28, 2026.
Other flights from La Crosse
Browse through other flights departing from La Crosse. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from La Crosse to Charleston
Discover the top airline that operate flights from La Crosse to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$604 | FlexibilityNo cancel fee | On-time71% |