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$410+ Cheap flights from La Crosse (LSE) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from La Crosse to South Carolina

Keep the following information in mind while searching for La Crosse to South Carolina flight deals. Data was last updated July 3, 2025.

Round-trip from

$410
(American Airlines)
From La Crosse to South Carolina
Search Deals

Find flight deals from La Crosse to South Carolina

Cheapest flights from La Crosse to South Carolina
Explore the most affordable flight options available from La Crosse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:52 pmLSE - CHS
1 stop4h 28mAmerican Airlines
Tue 11/115:54 pmCHS - LSE
1 stop4h 44mAmerican Airlines
Deal found 7/1$410
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:00 amLSE - CLT
1 stop4h 31mAmerican Airlines
Sun 7/206:04 pmCLT - LSE
1 stop6h 27mAmerican Airlines
Deal found 7/1$475
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2012:27 pmLSE - GSP
2 stops7h 28mAmerican Airlines
Thu 8/217:46 pmGSP - LSE
1 stop4h 33mAmerican Airlines
Deal found 7/1$496
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/96:00 amLSE - SAV
1 stop4h 37mAmerican Airlines
Tue 8/1212:29 pmSAV - LSE
1 stop6h 33mAmerican Airlines
Deal found 7/2$550

Cheapflights Fare Finder

Customize your flight search to find flights from La Crosse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from La Crosse to South Carolina that are best for you.

Fly from

La Crosse

Fly to

South Carolina

Route

Depart

Return

Price

La CrosseCharleston

LSE - CHS

LSECHS

La Crosse

Wed 11/5

2:52 pm-8:20 pm

1 stop4h 28m

Charleston

Tue 11/11

5:54 pm-9:38 pm

1 stop4h 44m

$410

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

Wed 7/16

6:00 am-11:31 am

1 stop4h 31m

Charlotte Douglas

Sun 7/20

6:04 pm-11:31 pm

1 stop6h 27m

$475

La CrosseGreenville

LSE - GSP

LSEGSP

La Crosse

Wed 8/20

12:27 pm-8:55 pm

2 stops7h 28m

Greenville

Thu 8/21

7:46 pm-11:19 pm

1 stop4h 33m

$496

La CrosseSavannah

LSE - SAV

LSESAV

La Crosse

Sat 8/9

6:00 am-11:37 am

1 stop4h 37m

Savannah/Hilton Head

Tue 8/12

12:29 pm-6:02 pm

1 stop6h 33m

$550

La CrosseCharlotte

LSE - CLT

LSECLT

La Crosse

Wed 7/9

6:00 am-11:31 am

1 stop4h 31m

$413

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from La Crosse to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 3, 2025.
Read reviews from past customers who have flown American Airlines from La Crosse to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Food

6.5

Overall

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Food

6.5

Overall

7.2

Crew

8.0

Entertainment

6.9

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from La Crosse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to South Carolina?

    Most people fly from La Crosse (LSE) if they book a flight from La Crosse to South Carolina. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • What are the most popular routes from La Crosse to South Carolina?

    Most travelers choose La Crosse - Charleston, La Crosse - Savannah/Hilton Head or La Crosse - Charlotte Douglas when deciding on the best route from La Crosse to South Carolina.

  • Can I find deals for flights from La Crosse to South Carolina that include hotel bookings?

    Yes. In addition to deals on La Crosse to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to South Carolina.

  • Can I find deals for business class flights from La Crosse to South Carolina?

    Yes. Cheapflights offers flight deals from La Crosse to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from La Crosse to South Carolina (average of $217). Flying from La Crosse to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from La Crosse to South Carolina

Discover the top airline that operate flights from La Crosse to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$514Average$674FlexibilityNo cancel feeOn-time71%

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