$230+ Cheap flights from La Crosse (LSE) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CHS
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from La Crosse to South CarolinaExplore the most affordable flight options available from La Crosse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from La Crosse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Sat 7/186:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Deal found 6/8![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:19 pm
LSE
- CHS
1 stop4h 56m
American Airlines
Wed 10/148:01 pm
CHS
- LSE
1 stop4h 18m
American Airlines
Deal found 6/9![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- CLT
1 stop6h 58m
American Airlines
Fri 7/108:27 pm
CLT
- LSE
1 stop4h 32m
American Airlines
Deal found 6/9![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:50 am
LSE
- SAV
2 stops10h 45m
American Airlines
Mon 11/167:37 am
SAV
- LSE
2 stops10h 55m
American Airlines
Deal found 6/9![American Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
LSE
- CHS
1 stop4h 54m
American Airlines
Wed 7/88:21 pm
CHS
- LSE
1 stop4h 38m
American Airlines
Deal found 6/5![American Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:53 pm
LSE
- GSP
1 stop5h 05m
American Airlines
Mon 7/277:20 pm
GSP
- LSE
1 stop5h 39m
American Airlines
Deal found 6/9![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Fri 7/316:26 pm
CLT
- LSE
1 stop6h 33m
American Airlines
Deal found 6/8![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:50 am
LSE
- CLT
1 stop6h 25m
American Airlines
Sun 11/221:01 pm
CLT
- LSE
1 stop5h 31m
American Airlines
Deal found 6/8![American Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:20 pm
LSE
- CLT
1 stop5h 34m
American Airlines
Tue 8/256:26 pm
CLT
- LSE
2 stops6h 56m
American Airlines
Deal found 6/7![American Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:54 am
LSE
- SAV
1 stop4h 32m
American Airlines
Sat 9/193:25 pm
SAV
- LSE
2 stops9h 55m
American Airlines
Deal found 6/6![American Airlines logo]()
$478
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:25 pm
LSE
- CLT
1 stop5h 33m
American Airlines
Sun 6/148:10 pm
CLT
- LSE
1 stop5h 09m
American Airlines
Deal found 6/5![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:26 pm
LSE
- SAV
2 stops8h 30m
American Airlines
Sun 9/2011:56 am
SAV
- LSE
1 stop5h 56m
American Airlines
Deal found 6/5![American Airlines logo]()
$542
Best flights from La Crosse to South CarolinaDiscover carefully curated flight deals from La Crosse to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from La Crosse to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Sat 7/186:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Deal found 6/8![American Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:42 am
LSE
- CHS
1 stop10h 22m
United Airlines
Tue 12/86:05 am
CHS
- LSE
1 stop13h 05m
United Airlines
Deal found 6/8![United Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- CLT
1 stop6h 58m
American Airlines
Fri 7/108:27 pm
CLT
- LSE
1 stop4h 32m
American Airlines
Deal found 6/9![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:20 pm
LSE
- CLT
1 stop5h 34m
American Airlines
Tue 8/251:06 pm
CLT
- LSE
1 stop4h 44m
American Airlines
Deal found 6/7![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
LSE
- CHS
1 stop4h 54m
American Airlines
Wed 7/88:21 pm
CHS
- LSE
1 stop4h 38m
American Airlines
Deal found 6/5![American Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:18 am
LSE
- CHS
2 stops8h 21m
American Airlines
Wed 10/148:01 pm
CHS
- LSE
1 stop4h 18m
American Airlines
Deal found 6/8![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Fri 7/316:26 pm
CLT
- LSE
1 stop6h 33m
American Airlines
Deal found 6/8![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:41 pm
LSE
- GSP
2 stops23h 29m
United Airlines
Sat 10/315:41 pm
GSP
- LSE
1 stop17h 15m
United Airlines
Deal found 6/5![United Airlines logo]()
$680
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:50 am
LSE
- CLT
1 stop6h 25m
American Airlines
Sun 11/2211:31 am
CLT
- LSE
1 stop7h 01m
American Airlines
Deal found 6/5![American Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:00 am
LSE
- SAV
2 stops10h 46m
American Airlines
Mon 7/201:24 pm
SAV
- LSE
1 stop4h 59m
American Airlines
Deal found 6/8![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:01 pm
LSE
- CHS
1 stop6h 30m
American Airlines
Tue 7/2812:44 pm
CHS
- LSE
1 stop5h 43m
American Airlines
Deal found 6/7![American Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
LSE
- SAV
1 stop4h 27m
American Airlines
Sun 8/237:00 am
SAV
- LSE
2 stops10h 56m
American Airlines
Deal found 6/5![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2012:01 pm
LSE
- GSP
2 stops10h 55m
American Airlines
Mon 7/272:35 pm
GSP
- LSE
2 stops10h 24m
American Airlines
Deal found 6/9![American Airlines logo]()
$669
Last-minute flights from La Crosse to South CarolinaDiscover last-minute flight deals from La Crosse to South Carolina. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to South Carolina. Data last updated June 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:25 pm
LSE
- CLT
1 stop5h 33m
American Airlines
Sun 6/148:10 pm
CLT
- LSE
1 stop5h 09m
American Airlines
Deal found 6/5![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:25 pm
LSE
- CLT
1 stop5h 33m
American Airlines
Sun 6/288:10 pm
CLT
- LSE
1 stop5h 09m
American Airlines
Deal found 6/8![American Airlines logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:26 pm
LSE
- CLT
1 stop17h 08m
Multiple Airlines
Sun 6/287:14 pm
CLT
- LSE
2 stops25h 00m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$625
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:00 am
LSE
- SAV
2 stops10h 46m
American Airlines
Mon 7/201:24 pm
SAV
- LSE
1 stop4h 59m
American Airlines
Deal found 6/8![American Airlines logo]()
$553
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:00 am
LSE
- CHS
1 stop4h 54m
American Airlines
Wed 7/88:21 pm
CHS
- LSE
1 stop4h 38m
American Airlines
Deal found 6/5![American Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:01 pm
LSE
- CLT
1 stop6h 58m
American Airlines
Fri 7/108:27 pm
CLT
- LSE
1 stop4h 32m
American Airlines
Deal found 6/9![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Sat 7/186:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Deal found 6/8![American Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:53 pm
LSE
- GSP
1 stop5h 05m
American Airlines
Mon 7/277:20 pm
GSP
- LSE
1 stop5h 39m
American Airlines
Deal found 6/9![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Fri 7/316:26 pm
CLT
- LSE
1 stop6h 33m
American Airlines
Deal found 6/8![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:01 pm
LSE
- CHS
1 stop6h 30m
American Airlines
Tue 7/2812:44 pm
CHS
- LSE
1 stop5h 43m
American Airlines
Deal found 6/7![American Airlines logo]()
$576
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:01 pm
LSE
- CLT
2 stops7h 48m
American Airlines
Sat 7/256:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Deal found 6/8![American Airlines logo]()
$610
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:01 pm
LSE
- CLT
2 stops7h 48m
American Airlines
Mon 7/276:26 pm
CLT
- LSE
1 stop6h 33m
American Airlines
Deal found 6/8![American Airlines logo]()
$685
One-way flights from La Crosse to South CarolinaSearch for one-way flight options from La Crosse to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from La Crosse to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:26 pm
LSE
- CLT
1 stop17h 08m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:21 am
LSE
- CLT
3 stops32h 34m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$272
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 pm
LSE
- CLT
1 stop24h 08m
United Airlines
Deal found 6/7![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:42 am
LSE
- CLT
1 stop14h 08m
United Airlines
Deal found 6/7![United Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:25 pm
LSE
- CLT
1 stop5h 33m
American Airlines
Deal found 6/8![American Airlines logo]()
$600
Find flight deals from La Crosse to South Carolina
Keep the following information in mind while searching for La Crosse to South Carolina flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $306 (American Airlines) |
One-way from | $230 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from La Crosse to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrosseCharlotte
LSE - CLT
LSECLT
La Crosse
Wed 7/8
5:53 pm-11:59 pm
1 stop5h 06m
Charlotte Douglas
Sat 7/18
6:26 pm-12:22 am
1 stop6h 56m
$306
La CrosseCharlotte
LSE - CLT
LSECLT
La Crosse
Sat 7/4
12:01 pm-7:59 pm
1 stop6h 58m
Charlotte Douglas
Fri 7/10
8:27 pm-11:59 pm
1 stop4h 32m
$345
La CrosseCharlotte
LSE - CLT
LSECLT
La Crosse
Thu 8/20
5:20 pm-11:54 pm
1 stop5h 34m
Charlotte Douglas
Tue 8/25
1:06 pm-4:50 pm
1 stop4h 44m
$345
Quickest round-trip
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Thu 7/2
6:00 am-11:54 am
1 stop4h 54m
Charleston
Wed 7/8
8:21 pm-11:59 pm
1 stop4h 38m
$400
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Wed 10/7
11:18 am-8:39 pm
2 stops8h 21m
Charleston
Wed 10/14
8:01 pm-11:19 pm
1 stop4h 18m
$420
La CrosseCharlotte
LSE - CLT
LSECLT
La Crosse
Fri 7/24
5:53 pm-11:59 pm
1 stop5h 06m
Charlotte Douglas
Fri 7/31
6:26 pm-11:59 pm
1 stop6h 33m
$420
La CrosseCharlotte
LSE - CLT
LSECLT
La Crosse
Thu 11/19
9:50 am-5:15 pm
1 stop6h 25m
Charlotte Douglas
Sun 11/22
11:31 am-5:32 pm
1 stop7h 01m
$440
La CrosseSavannah
LSE - SAV
LSESAV
La Crosse
Sun 6/28
6:00 am-5:46 pm
2 stops10h 46m
Savannah/Hilton Head
Mon 7/20
1:24 pm-5:23 pm
1 stop4h 59m
$553
La CrosseCharleston
LSE - CHS
LSECHS
La Crosse
Fri 7/24
12:01 pm-7:31 pm
1 stop6h 30m
Charleston
Tue 7/28
12:44 pm-5:27 pm
1 stop5h 43m
$576
La CrosseSavannah
LSE - SAV
LSESAV
La Crosse
Thu 8/20
6:00 am-11:27 am
1 stop4h 27m
Savannah/Hilton Head
Sun 8/23
7:00 am-4:56 pm
2 stops10h 56m
$600
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from La Crosse to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from La Crosse with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to South Carolina
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No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 10, 2026.
Read reviews from past customers who have flown American Airlines from La Crosse to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Overall
7.1
Crew
7.9
Entertainment
6.9
Boarding
7.5
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Comfort
7.2
Overall
7.1
Crew
7.9
Entertainment
6.9
Boarding
7.5
Food
6.4
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from La Crosse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for La Crosse to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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La Crosse and South Carolina flights
Browse other La Crosse and South Carolina flight options. Last updated on June 10, 2026.
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La Crosse to South Carolina flights
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Top airline flying from La Crosse to South Carolina
Discover the top airline that operate flights from La Crosse to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$604 | FlexibilityNo cancel fee | On-time71% |