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$79+ Cheap flights from O'Hare Intl (ORD) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — SAN
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to San Diego are usually found in October or September, booked 71 days in advance, depart on a Friday or Thursday and return on a Thursday

Cheap flight deals from O'Hare Intl to San Diego

Cheapest flights from O'Hare Intl to San Diego
Explore the most affordable flight options available from O'Hare Intl to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:25 amORD - SAN
1 stop13h 01mMultiple Airlines
Wed 12/241:30 pmSAN - ORD
Nonstop4h 32mMultiple Airlines
Deal found 12/2$178
This CheapOair deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:25 amORD - SAN
1 stop13h 01mFrontier
Mon 1/56:25 amSAN - ORD
1 stop15h 47mFrontier
Deal found 12/2$183
This Expedia deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:30 pmORD - SAN
1 stop8h 35mMultiple Airlines
Wed 1/75:10 pmSAN - ORD
Nonstop4h 27mMultiple Airlines
Deal found 12/2$187
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:30 pmORD - SAN
2 stops10h 29mFrontier
Wed 1/71:03 pmSAN - ORD
1 stop23h 54mFrontier
Deal found 12/2$189
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:30 pmORD - SAN
2 stops10h 29mFrontier
Thu 1/82:50 pmSAN - ORD
1 stop28h 42mFrontier
Deal found 12/2$190
This Alaska Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:59 pmORD - SAN
Nonstop4h 28mAlaska Airlines
Tue 12/235:31 pmSAN - ORD
Nonstop4h 28mAlaska Airlines
Deal found 12/1$194
This Alaska Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:58 pmORD - SAN
Nonstop4h 46mAlaska Airlines
Fri 12/268:05 amSAN - ORD
Nonstop4h 32mAlaska Airlines
Deal found 12/1$197
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:15 pmORD - SAN
Nonstop4h 36mUnited Airlines
Wed 1/77:00 amSAN - ORD
Nonstop4h 13mUnited Airlines
Deal found 12/2$202
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:15 amORD - SAN
Nonstop4h 33mAmerican Airlines
Sun 1/116:20 amSAN - ORD
Nonstop4h 09mAmerican Airlines
Deal found 12/2$204
This Alaska Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:58 pmORD - SAN
Nonstop4h 46mAlaska Airlines
Wed 12/311:30 pmSAN - ORD
Nonstop4h 32mAlaska Airlines
Deal found 12/1$207
This Kiwi.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amORD - SAN
1 stop18h 59mFrontier
Wed 12/316:25 amSAN - ORD
1 stop15h 47mFrontier
Deal found 12/1$208
This Kiwi.com deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:34 pmORD - SAN
2 stops24h 37mMultiple Airlines
Fri 1/309:45 pmSAN - ORD
1 stop17h 06mMultiple Airlines
Deal found 12/3$212

Find flight deals from O'Hare Intl to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$161
(American Airlines)

One-way from

$79
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$319

Good round-trip deal

$180 or less

Good one-way deal

$98 or less
Provider with most accurate pricing for Chicago O'Hare Intl-San Diego flight deals.
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Provider most trusted by Cheapflights users for Chicago O'Hare Intl-San Diego flights.
Search Deals
From Chicago O'Hare Intl to San Diego
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One-way flight from Chicago O'Hare Intl to San Diego
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($109 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Chicago O'Hare Intl to San Diego.
Search Deals
Price to beat on a one-way flight from Chicago O'Hare Intl to San Diego.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to San Diego that are best for you.

Fly from

O'Hare Intl

Fly to

San Diego

Route

Depart

Return

Price

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Tue 2/3

2:15 pm-8:50 pm

2 stops8h 35m

San Diego

Tue 2/10

9:40 am-10:35 pm

2 stops10h 55m

$169

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Tue 1/20

1:00 pm-7:10 pm

1 stop8h 10m

San Diego

Mon 1/26

10:30 am-9:50 pm

1 stop9h 20m

$175

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/21

1:00 pm-8:50 pm

2 stops9h 50m

San Diego

Tue 1/27

9:00 am-10:35 pm

2 stops11h 35m

$179

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Fri 2/6

3:44 pm-6:26 pm

Nonstop4h 42m

San Diego

Tue 2/10

6:15 am-5:10 pm

1 stop8h 55m

$185

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/7

9:00 am-11:43 am

Nonstop4h 43m

San Diego

Tue 1/13

11:49 am-11:50 pm

1 stop10h 01m

$189

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/21

7:15 am-11:50 am

1 stop6h 35m

San Diego

Sat 1/24

2:20 pm-10:35 pm

1 stop6h 15m

$192

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 1/15

3:44 pm-6:26 pm

Nonstop4h 42m

San Diego

Mon 1/19

5:10 pm-11:37 pm

Nonstop4h 27m

$197

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Tue 1/13

7:15 am-2:45 pm

2 stops9h 30m

San Diego

Wed 1/21

9:40 am-10:35 pm

2 stops10h 55m

$199

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Mon 1/19

9:00 am-11:43 am

Nonstop4h 43m

San Diego

Sun 1/25

6:15 am-11:50 pm

1 stop15h 35m

$200

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 1/28

2:20 pm-10:42 pm

1 stop10h 22m

San Diego

Sat 1/31

11:00 am-11:53 pm

1 stop10h 53m

$206

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Showing 1-10 of 23 results
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Compare providers for flights from O'Hare Intl to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to San Diego in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
CheapfaremartPrice Accuracy-Trust Score*1 star
CheapOairPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-San Diego flights, users find the pricing of CheapOair to be most consistent on Cheapflights vs. CheapOair Users can find the same prices on Chicago O'Hare Intl Airport-San Diego flight deals on Cheapflights vs. CheapOair >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-San Diego flights, Cheapflights users trust CheapOair the most. CheapOair has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to San Diego

How far ahead should I book a flight from Chicago O'Hare Intl Airport to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from O'Hare Intl to San Diego. Price data was last updated on November 28, 2025.

The price you pay for your flight from Chicago O'Hare Intl Airport to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 71 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to San Diego?

Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to San Diego (average of $88). Flying from Chicago O'Hare Intl Airport to San Diego in May is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SAN?

Find hourly flight availability from O'Hare Intl to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s optimal to fly from Chicago O'Hare Intl Airport to San Diego at noon. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to San Diego?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to San Diego. Price data was last updated on November 29, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to San Diego flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Chicago O'Hare Intl Airport to San Diego flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago O'Hare Intl Airport to San Diego trip
Airports
ORD

For a quick departure, take the "L" train to ORD, avoiding Chicago traffic delays common with taxis or rideshares.

Read more about ORDby Ramsey Qubein
SAN

Upon arrival at SAN, use the free San Diego Flyer shuttle to connect to the Old Town Transit Center for easy downtown access.

Read more about SANby Blane Bachelor
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on ORD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Blane Bachelor

Blane Bachelor

Expert on SAN

Blane Bachelor

Blane Bachelor

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Read more

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated December 4, 2025.
See what other customers who have flown with Alaska Airlines, United Airlines, and American Airlines from Chicago O'Hare Intl Airport to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,401 reviews
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
United Airlines
7.4
Good
9,066 reviews
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,046 reviews
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Spirit Airlines
6.3
Okay
8,159 reviews
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,092 reviews
Alaska Airlines
8.0
Very good
11,401 reviews

Food

7.1

Crew

8.5

Boarding

8.1

Overall

8.0

Entertainment

7.0

Comfort

7.8

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Chicago O'Hare Intl?

    San Diego (SAN) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to San Diego. You should not have trouble finding flights to San Diego from Chicago O'Hare Intl; the airport handles an average of 25 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 8 airlines have flights to the San Diego airport from Chicago O'Hare Intl. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Chicago O'Hare Intl Airport to San Diego?

    Departing from Chicago O'Hare Intl Airport to San Diego will take you 4h 42m. There are 1719 mi between Chicago O'Hare Intl Airport and San Diego. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to San Diego round-trip?

    According to our current data, Spirit Airlines ($84), Frontier ($100), and Hawaiian Airlines ($138) offers the cheapest pricing from Chicago O'Hare Intl Airport to San Diego. These flights start at 73% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to San Diego one-way?

    $43 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Frontier and Alaska Airlines, with prices starting from $58 and $71, respectively.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to San Diego?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to San Diego are Japan Airlines (80%), Air Canada (77%) and United Airlines (77%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to San Diego?

    Looking at all options, your cheapest flight can be booked for $76. While the most popular route (Chicago O'Hare Intl - San Diego) can be booked for $91 on average, our data indicates $664 when flying from Chicago O'Hare Intl Airport to San Diego.

  • Can I find deals for flights from O'Hare Intl to San Diego that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to San Diego.

  • Can I find deals for business class flights from O'Hare Intl to San Diego?

    Yes. Cheapflights offers flight deals from O'Hare Intl to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to San Diego (average of $88). Flying from Chicago O'Hare Intl Airport to San Diego in May is currently the most expensive (average of $198). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Julian
National City

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Alternative routes for O'Hare Intl to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from O'Hare Intl to San Diego

Discover the top 8 airlines that operate flights from O'Hare Intl to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$87Average$199FlexibilityNo cancel feeOn-time65%
FrontierCheapest$103Average$205FlexibilityNo cancel feeOn-time62%
Alaska AirlinesCheapest$142Average$238FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$164Average$358FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$166Average$385FlexibilityNo cancel feeOn-time69%
Hawaiian AirlinesCheapest$168Average$237FlexibilityNo cancel feeOn-time85%
DeltaCheapest$256Average$312FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$261Average$501FlexibilityNo cancel feeOn-time63%

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