$355+ Cheap flights from Charleston to La Crosse (CHS - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LSE
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to La Crosse
Cheapest
Best
Last-minute
Cheapest flights from Charleston to La CrosseExplore the most affordable flight options available from Charleston to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Charleston to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:16 am -
1 stop5h 37m
Sun 10/187:04 am -
1 stop6h 58m
Deal found 9/6![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:17 pm -
1 stop6h 59m
Sun 11/155:57 am -
2 stops6h 41m
Deal found 9/9![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:13 am -
1 stop5h 40m
Tue 11/175:57 am -
1 stop4h 27m
Deal found 9/9![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:03 pm -
2 stops7h 13m
Wed 11/1812:24 pm -
2 stops9h 13m
Deal found 9/9![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:17 pm -
1 stop6h 59m
Wed 12/96:00 am -
1 stop4h 24m
Deal found 9/9![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:13 am -
1 stop5h 40m
Wed 12/96:00 am -
1 stop4h 24m
Deal found 9/9![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:09 am -
1 stop5h 47m
Fri 11/276:39 am -
1 stop7h 39m
Deal found 9/9![American Airlines logo]()
$430
Best flights from Charleston to La CrosseDiscover carefully curated flight deals from Charleston to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Charleston to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:16 am -
1 stop5h 37m
Sun 10/187:04 am -
1 stop6h 58m
Deal found 9/6![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:17 pm -
1 stop6h 59m
Tue 11/175:57 am -
2 stops10h 01m
Deal found 9/9![American Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:13 am -
1 stop5h 40m
Tue 11/175:57 am -
1 stop4h 27m
Deal found 9/9![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:03 pm -
2 stops7h 13m
Wed 11/186:52 pm -
1 stop4h 28m
Deal found 9/9![American Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:18 am -
1 stop5h 04m
Tue 9/295:53 am -
1 stop6h 23m
Deal found 9/6![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:46 pm -
1 stop5h 34m
Mon 9/2812:02 pm -
1 stop5h 40m
Deal found 9/6![American Airlines logo]()
$446
Last-minute flights from Charleston to La CrosseDiscover last-minute flight deals from Charleston to La Crosse. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to La Crosse. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:18 am -
1 stop5h 04m
Tue 9/295:53 am -
1 stop6h 23m
Deal found 9/6![American Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:18 am -
1 stop5h 04m
Tue 9/295:53 am -
1 stop6h 23m
Deal found 9/6![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:46 pm -
1 stop5h 34m
Mon 9/2812:02 pm -
1 stop5h 40m
Deal found 9/6![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:46 pm -
1 stop5h 34m
Tue 9/295:53 am -
1 stop6h 23m
Deal found 9/6![American Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:16 am -
1 stop5h 37m
Sun 10/187:04 am -
1 stop6h 58m
Deal found 9/6![American Airlines logo]()
$355
Find flight deals from Charleston to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Charleston to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Wed 10/7
7:16 am-11:53 am
1 stop5h 37m
La Crosse
Sun 10/18
7:04 am-3:02 pm
1 stop6h 58m
$355
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Thu 11/12
12:17 pm-6:16 pm
1 stop6h 59m
La Crosse
Tue 11/17
5:57 am-4:58 pm
2 stops10h 01m
$361
Quickest round-trip
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Wed 11/11
7:13 am-11:53 am
1 stop5h 40m
La Crosse
Tue 11/17
5:57 am-11:24 am
1 stop4h 27m
$370
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Wed 11/11
12:03 pm-6:16 pm
2 stops7h 13m
La Crosse
Wed 11/18
6:52 pm-12:20 am
1 stop4h 28m
$376
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Tue 9/22
7:18 am-11:22 am
1 stop5h 04m
La Crosse
Tue 9/29
5:53 am-1:16 pm
1 stop6h 23m
$442
CharlestonLa Crosse
CHS Charleston - LSE La Crosse
CHSLSE
Charleston
Tue 9/22
7:46 pm-12:20 am
1 stop5h 34m
La Crosse
Mon 9/28
12:02 pm-6:42 pm
1 stop5h 40m
$446
Sorted by cheapest first
Compare providers for flights from Charleston to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to La Crosse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Charleston with our price prediction graph.
CHS-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with American Airlines from Charleston to La Crosse by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Crew
7.9
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Boarding
7.5
Entertainment
6.8
Comfort
7.2
Crew
7.9
Overall
7.1
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Charleston to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Top airline flying from Charleston to La Crosse
Discover the top airline that operate flights from Charleston to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$376 | Average$586 | FlexibilityNo cancel fee | On-time71% |