HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$110+ Cheap flights from O'Hare Intl (ORD) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — GSP
Jul 11 — Jul 181
Sat 7/11
Sat 7/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from O'Hare Intl to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Chicago O'Hare Intl to Greenville are usually found in January or July, booked 60 days in advance, depart on a Saturday or Thursday and return on a Thursday

Cheap flight deals from O'Hare Intl to Greenville

Cheapest flights from O'Hare Intl to Greenville
Explore the most affordable flight options available from O'Hare Intl to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:05 am
ORD
-
GSP
1 stop10h 51m
Multiple Airlines
Sun 7/128:37 am
GSP
-
ORD
1 stop28h 38m
Multiple Airlines
Deal found 6/7$239
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
ORD
-
GSP
1 stop22h 52m
Multiple Airlines
Thu 8/68:37 am
GSP
-
ORD
1 stop28h 38m
Multiple Airlines
Deal found 6/6$254
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:55 pm
ORD
-
GSP
Nonstop2h 05m
United Airlines
Sat 7/46:10 am
GSP
-
ORD
Nonstop2h 20m
United Airlines
Deal found 6/9$269
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:17 pm
ORD
-
GSP
Nonstop2h 09m
United Airlines
Sun 7/126:10 am
GSP
-
ORD
Nonstop2h 20m
United Airlines
Deal found 6/8$271
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:59 pm
ORD
-
GSP
Nonstop1h 59m
American Airlines
Tue 7/711:31 am
GSP
-
ORD
Nonstop2h 09m
American Airlines
Deal found 6/7$277
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:40 pm
ORD
-
GSP
Nonstop1h 51m
American Airlines
Mon 11/28:14 pm
GSP
-
ORD
Nonstop2h 16m
American Airlines
Deal found 6/6$280
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:00 am
ORD
-
GSP
Nonstop2h 01m
American Airlines
Mon 7/67:30 pm
GSP
-
ORD
1 stop5h 31m
American Airlines
Deal found 6/9$287
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:17 pm
ORD
-
GSP
1 stop4h 43m
American Airlines
Thu 7/97:20 pm
GSP
-
ORD
1 stop5h 10m
American Airlines
Deal found 6/10$289

Find flight deals from O'Hare Intl to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$239
(Kiwi.com)

One-way from

$110
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$317

Good round-trip deal

$289 or less

Good one-way deal

$288 or less
Provider with most accurate pricing for Chicago O'Hare Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Greenville flights.
Search Deals
From Chicago O'Hare Intl to Greenville
Search Deals
One-way flight from Chicago O'Hare Intl to Greenville
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Chicago O'Hare Intl to Greenville.
Search Deals
Price to beat on a one-way flight from Chicago O'Hare Intl to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 7/1

6:55 am-9:55 am

Nonstop2h 00m

Greenville

Wed 7/8

5:43 pm-7:00 pm

Nonstop2h 17m

$269

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 9/10

6:29 am-9:35 am

Nonstop2h 06m

Greenville

Mon 9/14

6:10 pm-7:32 pm

Nonstop2h 22m

$269

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 7/17

6:17 pm-9:26 pm

Nonstop2h 09m

Greenville

Mon 7/20

7:40 pm-11:31 pm

1 stop4h 51m

$279

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 7/9

6:17 pm-9:26 pm

Nonstop2h 09m

Greenville

Sun 7/12

6:10 am-7:30 am

Nonstop2h 20m

$279

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/1

1:55 pm-5:00 pm

Nonstop2h 05m

Greenville

Thu 8/6

7:40 pm-11:31 pm

1 stop4h 51m

$287

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 8/8

7:00 am-11:51 am

1 stop3h 51m

Greenville

Sun 8/9

6:55 am-10:13 am

1 stop4h 18m

$289

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 10/15

5:30 am-10:58 am

1 stop4h 28m

Greenville

Sun 10/18

7:15 am-12:37 pm

1 stop6h 22m

$289

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Tue 8/4

8:40 am-2:20 pm

1 stop4h 40m

Greenville

Sat 8/8

7:40 pm-11:31 pm

1 stop4h 51m

$295

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 7/3

1:40 pm-9:48 pm

1 stop7h 08m

Greenville

Thu 7/9

7:10 am-10:37 am

1 stop4h 27m

$297

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Fri 7/31

6:35 am-2:01 pm

1 stop6h 26m

Greenville

Sun 8/2

5:44 am-8:35 am

1 stop3h 51m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from O'Hare Intl to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Greenville in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Greenville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Greenville?

The price you pay for your flight from Chicago O'Hare Intl Airport to Greenville may vary depending on when you book. For the best chance of a lower fare, look to book 59 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $247). Flying from Chicago O'Hare Intl Airport to Greenville in April is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to GSP?

Find hourly flight availability from O'Hare Intl to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 11, 2026.

One of the essential ways to save on airfare from Chicago O'Hare Intl Airport to Greenville is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 10% on airfare.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Greenville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Greenville. Price data was last updated on June 8, 2026.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Greenville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 11, 2026.
Read through reviews of airlines operating flights from Chicago O'Hare Intl Airport to Greenville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,399 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,399 reviews
Delta
7.9
Good
8,399 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,805 reviews
Delta
7.9
Good
8,399 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,640 reviews
Delta
7.9
Good
8,399 reviews

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Comfort

7.8

Food

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Chicago O'Hare Intl?

    Located just 10.4 mi from the city center, Greenville is the airport most travelers will use when flying to Greenville from Chicago O'Hare Intl. Booking flights from Chicago O'Hare Intl to Greenville (GSP) should be relatively easy as there are 17 daily inbound flights from Chicago O'Hare Intl from 3 different airlines.

  • How long is the flight from Chicago O'Hare Intl Airport to Greenville?

    A quick flight from Chicago O'Hare Intl Airport to Greenville can take about 2h. United Airlines provides one of the quickest options available for as low as $269. There are 577 mi between Chicago O'Hare Intl Airport and Greenville. Most flights are nonstop.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Greenville round-trip?

    Flying on Delta is currently your cheapest option to Greenville, with prices starting at $146. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $202 and $205, respectively. You may be able to fly from Chicago O'Hare Intl Airport to Greenville for 52% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to Greenville one-way?

    $118 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $133 and $133, respectively.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Greenville?

    Before booking your flight to Greenville from Chicago O'Hare Intl Airport, check out the most reliable airlines to get you to your destination on time: Republic Airways (96%), United Airlines (84%), Avianca( 83%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Greenville?

    While on average a flight from Chicago O'Hare Intl Airport to Greenville is generally $349, our data shows the cheapest flight currently is $250. When looking at the most popular route, (Chicago O'Hare Intl - Greenville), you can expect to pay $269 for that flight.

  • Can I find deals for flights from O'Hare Intl to Greenville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Greenville.

  • Can I find deals for business class flights from O'Hare Intl to Greenville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Greenville (average of $247). Flying from Chicago O'Hare Intl Airport to Greenville in April is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from O'Hare Intl to Greenville

Discover the top 3 airlines that operate flights from O'Hare Intl to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$146Average$212FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$202Average$295FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$205Average$322FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.