$91+ Cheap flights from O'Hare Intl (ORD) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Nov 20 — Nov 271
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from O'Hare Intl to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from O'Hare Intl to South CarolinaExplore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:49 am -
1 stop5h 10m
Mon 12/75:34 pm -
1 stop4h 19m
Deal found 10/18![Delta logo]()
$263
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:30 am -
1 stop7h 03m
Tue 12/152:18 pm -
1 stop5h 51m
Deal found 10/19![Delta logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:19 pm -
1 stop18h 19m
Mon 12/78:58 pm -
2 stops18h 32m
Deal found 10/19![Multiple Airlines logo]()
$276
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1412:05 pm -
Nonstop2h 21m
Mon 1/187:24 am -
Nonstop2h 41m
Deal found 10/20![American Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:59 am -
2 stops22h 39m
Mon 11/234:57 pm -
1 stop7h 37m
Deal found 10/20![Multiple Airlines logo]()
$282
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:32 pm -
Nonstop2h 34m
Thu 11/1912:18 pm -
Nonstop2h 41m
Deal found 10/16![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:52 pm -
2 stops16h 56m
Mon 11/234:57 pm -
1 stop7h 37m
Deal found 10/20![Multiple Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:47 am -
Nonstop2h 34m
Thu 11/2610:23 am -
1 stop5h 16m
Deal found 10/20![United Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:51 am -
1 stop21h 47m
Mon 11/168:58 pm -
2 stops22h 32m
Deal found 10/20![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:19 pm -
1 stop18h 31m
Mon 12/71:53 pm -
2 stops33h 07m
Deal found 10/20![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:19 pm -
1 stop18h 31m
Tue 12/84:03 pm -
2 stops49h 01m
Deal found 10/20![Multiple Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:58 pm -
Nonstop2h 22m
Sun 12/204:10 pm -
Nonstop2h 37m
Deal found 10/20![American Airlines logo]()
$298
Best flights from O'Hare Intl to South CarolinaDiscover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:49 am -
1 stop5h 10m
Mon 12/75:34 pm -
1 stop4h 19m
Deal found 10/18![Delta logo]()
$263
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:47 am -
Nonstop2h 34m
Sun 11/227:00 pm -
Nonstop2h 40m
Deal found 10/19![United Airlines logo]()
$337
This KAYAK deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:46 pm -
Nonstop2h 09m
Sun 11/225:53 am -
Nonstop2h 37m
Deal found 10/19![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/87:00 am -
Nonstop2h 10m
Sun 4/115:25 pm -
Nonstop2h 16m
Deal found 10/20![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/149:30 am -
1 stop5h 58m
Sun 4/186:50 pm -
1 stop6h 00m
Deal found 10/21![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:30 pm -
Nonstop2h 34m
Sun 11/223:29 pm -
Nonstop2h 36m
Deal found 10/17![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/315:55 pm -
1 stop4h 59m
Sun 4/45:40 am -
1 stop5h 22m
Deal found 10/18![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1910:30 am -
1 stop6h 24m
Tue 12/227:41 pm -
1 stop5h 18m
Deal found 10/17![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/271:30 pm -
1 stop4h 20m
Sat 4/310:21 am -
1 stop4h 51m
Deal found 10/20![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:00 am -
1 stop5h 16m
Sat 11/73:37 pm -
1 stop5h 34m
Deal found 10/19![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/179:30 am -
1 stop4h 19m
Sun 4/183:42 pm -
1 stop6h 28m
Deal found 10/17![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:00 am -
1 stop5h 09m
Sat 11/146:24 am -
1 stop6h 55m
Deal found 10/20![American Airlines logo]()
$473
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:29 am -
Nonstop2h 01m
Fri 11/272:19 pm -
Nonstop2h 12m
Deal found 10/19![United Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:25 am -
1 stop9h 55m
Wed 1/62:59 pm -
1 stop4h 33m
Deal found 10/19![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:40 pm -
1 stop6h 16m
Sun 11/155:09 am -
1 stop6h 53m
Deal found 10/16![American Airlines logo]()
$490
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:55 pm -
Nonstop2h 03m
Fri 11/272:19 pm -
Nonstop2h 12m
Deal found 10/19![United Airlines logo]()
$416
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:30 am -
1 stop5h 09m
Tue 11/37:20 am -
1 stop6h 39m
Deal found 10/17![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:50 am -
1 stop4h 38m
Wed 11/252:52 pm -
1 stop7h 52m
Deal found 10/20![United Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:00 am -
1 stop5h 09m
Sun 11/85:09 am -
1 stop4h 51m
Deal found 10/20![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:27 am -
1 stop6h 12m
Wed 11/45:00 pm -
1 stop4h 38m
Deal found 10/18![Delta logo]()
$421
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:32 pm -
Nonstop2h 34m
Mon 11/303:29 pm -
Nonstop2h 36m
Deal found 10/18![United Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:05 am -
1 stop5h 05m
Sun 11/152:35 pm -
1 stop6h 29m
Deal found 10/17![American Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:30 am -
1 stop6h 01m
Fri 11/132:18 pm -
1 stop7h 31m
Deal found 10/17![Delta logo]()
$426
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:15 am -
Nonstop2h 38m
Sun 12/276:39 pm -
Nonstop2h 40m
Deal found 10/17![United Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:05 am -
1 stop5h 04m
Sun 11/15:09 am -
1 stop4h 51m
Deal found 10/16![American Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:05 am -
1 stop6h 25m
Sat 10/3112:23 pm -
2 stops9h 07m
Deal found 10/17![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/68:40 am -
1 stop4h 44m
Wed 2/102:26 pm -
Nonstop2h 34m
Deal found 10/17![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:40 pm -
1 stop5h 19m
Sat 11/146:24 am -
2 stops7h 35m
Deal found 10/20![American Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:20 am -
2 stops8h 10m
Wed 11/412:23 pm -
2 stops9h 07m
Deal found 10/16![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:47 am -
Nonstop2h 34m
Fri 11/278:30 am -
Nonstop2h 36m
Deal found 10/20![United Airlines logo]()
$468
Last-minute flights from O'Hare Intl to South CarolinaDiscover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated October 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:47 am -
1 stop3h 36m
Sat 11/141:28 pm -
1 stop5h 59m
Deal found 10/21![American Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:51 am -
1 stop21h 47m
Mon 11/168:58 pm -
2 stops22h 32m
Deal found 10/20![Multiple Airlines logo]()
$292
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/111:22 pm -
1 stop6h 35m
Sun 11/158:35 pm -
1 stop4h 26m
Deal found 10/19![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:55 pm -
1 stop6h 42m
Fri 11/136:00 am -
1 stop5h 05m
Deal found 10/20![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:59 pm -
Nonstop2h 18m
Mon 11/167:13 am -
Nonstop2h 47m
Deal found 10/19![American Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:55 am -
1 stop23h 18m
Thu 11/1910:12 am -
2 stops9h 33m
Deal found 10/18![Multiple Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:32 pm -
Nonstop2h 34m
Thu 11/1912:18 pm -
Nonstop2h 41m
Deal found 10/16![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:54 am -
1 stop4h 42m
Thu 11/199:04 am -
1 stop4h 22m
Deal found 10/16![American Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:59 am -
2 stops22h 39m
Mon 11/234:57 pm -
1 stop7h 37m
Deal found 10/20![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:51 am -
1 stop21h 47m
Wed 11/2510:15 pm -
2 stops18h 42m
Deal found 10/20![Multiple Airlines logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:47 am -
Nonstop2h 34m
Thu 11/2610:23 am -
1 stop5h 16m
Deal found 10/20![United Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:52 pm -
2 stops16h 56m
Mon 11/234:57 pm -
1 stop7h 37m
Deal found 10/20![Multiple Airlines logo]()
$287
One-way flights from O'Hare Intl to South CarolinaSearch for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
2 stops13h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:35 pm -
2 stops36h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:15 am -
2 stops23h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$117
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:38 am -
Nonstop2h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
1 stop26h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![Multiple Airlines logo]()
$124
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:40 pm -
Nonstop2h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/57:52 pm -
1 stop18h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
2 stops25h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$126
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:32 am -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$131
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:36 am -
1 stop4h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Delta logo]()
$132
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/412:05 pm -
1 stop4h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:00 pm -
2 stops39h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$135
Find flight deals from O'Hare Intl to South Carolina
Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated October 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $263 (American Airlines) |
One-way from | $91 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $395 |
Good round-trip deal | $319 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Wed 12/16
10:38 am-2:00 pm
Nonstop2h 22m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$122
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Sat 12/12
5:30 am-1:23 pm
1 stop6h 53m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$131
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Mon 12/14
11:39 am-6:02 pm
1 stop5h 23m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$132
ChicagoGreenville
ORD Chicago O'Hare Intl - GSP Greenville
ORDGSP
Chicago O'Hare Intl
Fri 11/13
7:55 am-8:12 pm
2 stops11h 17m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$143
ChicagoMyrtle Beach
ORD Chicago O'Hare Intl - MYR Myrtle Beach Intl
ORDMYR
Chicago O'Hare Intl
Tue 1/5
9:40 am-3:04 pm
2 stops28h 24m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$146
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Tue 11/10
10:40 am-1:56 pm
Nonstop2h 16m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Fri 1/1
7:25 am-2:46 pm
1 stop6h 21m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Fri 1/1
2:15 pm-5:50 pm
Nonstop2h 35m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
ChicagoGreenville
ORD Chicago O'Hare Intl - GSP Greenville
ORDGSP
Chicago O'Hare Intl
Fri 12/18
1:10 pm-7:53 am
2 stops41h 43m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
ChicagoMyrtle Beach
ORD Chicago O'Hare Intl - MYR Myrtle Beach Intl
ORDMYR
Chicago O'Hare Intl
Mon 11/30
4:00 pm-9:55 am
1 stop16h 55m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$192
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from O'Hare Intl to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
ORD-MYR
ORD-CHS
ORD-GSP
ORD-CAE
ORD-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina
ORD-USSC
ORD-MYR
ORD-CHS
ORD-GSP
ORD-CAE
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?
Currently, November is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $357). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $407). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to SC?
Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 21, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.
Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina
Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 21, 2026.
The most flights from ORD to USSC are scheduled on a Monday (19 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to South Carolina?
Airfare is below average for this route at the moment.
Chicago O'Hare Intl Airport to South Carolina flights typically cost between $318 and $477 in February.The cheapest round-trip price found within the last 5 days was $263 on Delta (Feb 4-Feb 6).
How far ahead should I book a flight from Chicago O'Hare Intl Airport to South Carolina?
The price you pay for your flight from Chicago O'Hare Intl Airport to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on October 17, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 21, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for O'Hare Intl to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from O'Hare Intl to South Carolina by cabin class
Find flights from O'Hare Intl to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
O'Hare Intl and South Carolina flights
Browse other O'Hare Intl and South Carolina flight options. Last updated on October 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
O'Hare Intl to South Carolina flights
Consider these flights traveling from O'Hare Intl to South Carolina.
Top 3 airlines flying from O'Hare Intl to South Carolina
Discover the top 3 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$152 | Average$277 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$372 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$391 | FlexibilityNo cancel fee | On-time69% |