$81+ Cheap flights from O'Hare Intl (ORD) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Jul 7 — Jul 141
Round-trip
1 adult, Economy
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Cheapest flights from O'Hare Intl to South CarolinaExplore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:05 am
ORD
- GSP
1 stop7h 02m
Multiple Airlines
Mon 8/104:57 pm
GSP
- ORD
1 stop20h 18m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:55 am
ORD
- GSP
1 stop23h 02m
Multiple Airlines
Fri 8/286:41 pm
GSP
- ORD
1 stop18h 44m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$235
This Frontier deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:31 pm
ORD
- CLT
1 stop10h 10m
Frontier
Mon 8/245:59 pm
CLT
- ORD
1 stop7h 43m
Frontier
Deal found 6/2![Frontier logo]()
$244
This Super.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Sun 7/55:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/2![Frontier logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Mon 8/316:40 pm
CLT
- ORD
1 stop18h 45m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$248
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:31 pm
ORD
- CLT
1 stop10h 10m
Frontier
Tue 7/76:41 pm
CLT
- ORD
1 stop18h 34m
Frontier
Deal found 6/4![Frontier logo]()
$249
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/4![Frontier logo]()
$250
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Mon 7/68:28 pm
CLT
- ORD
1 stop27h 59m
Frontier
Deal found 6/3![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
ORD
- GSP
1 stop22h 52m
Multiple Airlines
Thu 8/68:37 am
GSP
- ORD
1 stop28h 38m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$254
This CheapOair deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Wed 7/296:48 pm
CLT
- ORD
2 stops31h 01m
Frontier
Deal found 6/2![Frontier logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Tue 7/71:38 pm
CLT
- ORD
2 stops31h 15m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$257
Best flights from O'Hare Intl to South CarolinaDiscover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
Discover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 7, 2026.
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:29 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Wed 7/158:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/5![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:30 am
ORD
- AGS
1 stop4h 42m
Delta
Sat 7/186:45 pm
AGS
- ORD
1 stop6h 08m
Delta
Deal found 6/7![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 am
ORD
- FLO
1 stop5h 10m
American Airlines
Wed 7/225:17 am
FLO
- ORD
1 stop6h 43m
American Airlines
Deal found 6/4![American Airlines logo]()
$279
This JetBlue deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:40 am
ORD
- SAV
1 stop7h 52m
JetBlue
Wed 7/1510:56 am
SAV
- ORD
1 stop7h 38m
JetBlue
Deal found 6/5![JetBlue logo]()
$433
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:30 am
ORD
- CHS
1 stop4h 56m
Delta
Wed 11/118:20 am
CHS
- ORD
1 stop4h 46m
Delta
Deal found 6/4![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:55 pm
ORD
- GSP
Nonstop2h 05m
United Airlines
Thu 8/67:40 pm
GSP
- ORD
1 stop4h 51m
United Airlines
Deal found 6/6![United Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:15 pm
ORD
- AGS
1 stop6h 17m
American Airlines
Wed 8/1910:18 am
AGS
- ORD
1 stop7h 30m
American Airlines
Deal found 6/7![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:25 pm
ORD
- CHS
Nonstop2h 37m
United Airlines
Tue 10/133:00 pm
CHS
- ORD
1 stop7h 30m
United Airlines
Deal found 6/5![United Airlines logo]()
$288
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:44 pm
ORD
- CAE
1 stop4h 05m
Delta
Sun 7/195:35 am
CAE
- ORD
1 stop4h 00m
Delta
Deal found 6/2![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:14 pm
ORD
- AGS
1 stop7h 13m
American Airlines
Mon 10/196:11 am
AGS
- ORD
1 stop4h 49m
American Airlines
Deal found 6/5![American Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:03 am
ORD
- CAE
1 stop6h 03m
Delta
Mon 7/205:35 am
CAE
- ORD
1 stop4h 00m
Delta
Deal found 6/3![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:00 am
ORD
- MYR
Nonstop2h 19m
United Airlines
Wed 7/223:15 pm
MYR
- ORD
Nonstop2h 34m
United Airlines
Deal found 6/2![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:54 am
ORD
- FLO
1 stop5h 02m
American Airlines
Tue 9/151:43 pm
FLO
- ORD
1 stop6h 55m
American Airlines
Deal found 6/2![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:40 am
ORD
- GSP
1 stop5h 01m
Delta
Sun 8/238:49 am
GSP
- ORD
1 stop4h 51m
Delta
Deal found 6/4![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:05 am
ORD
- CHS
Nonstop2h 31m
United Airlines
Sat 8/226:30 am
CHS
- ORD
Nonstop2h 30m
United Airlines
Deal found 6/3![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:30 am
ORD
- GSP
1 stop4h 28m
Delta
Sun 10/187:15 am
GSP
- ORD
1 stop6h 22m
Delta
Deal found 6/3![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Sun 6/286:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 6/3![United Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:00 am
ORD
- AGS
1 stop4h 17m
American Airlines
Sun 8/26:00 am
AGS
- ORD
1 stop6h 33m
American Airlines
Deal found 6/6![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:30 am
ORD
- CLT
1 stop7h 05m
Delta
Tue 7/75:02 pm
CLT
- ORD
1 stop4h 29m
Delta
Deal found 6/7![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:55 pm
ORD
- CAE
Nonstop2h 21m
United Airlines
Mon 6/297:45 pm
CAE
- ORD
1 stop4h 46m
United Airlines
Deal found 6/6![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:40 pm
ORD
- GSP
1 stop7h 08m
Delta
Thu 7/97:10 am
GSP
- ORD
1 stop4h 27m
Delta
Deal found 6/6![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Sun 6/216:10 am
GSP
- ORD
Nonstop2h 19m
United Airlines
Deal found 6/5![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am
ORD
- CHS
1 stop5h 10m
Delta
Sat 10/312:36 pm
CHS
- ORD
1 stop5h 12m
Delta
Deal found 6/3![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:30 am
ORD
- CLT
1 stop6h 41m
United Airlines
Sat 7/1110:30 am
CLT
- ORD
Nonstop2h 24m
United Airlines
Deal found 6/6![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/79:00 am
ORD
- FLO
1 stop4h 10m
American Airlines
Fri 7/102:35 pm
FLO
- ORD
1 stop6h 16m
American Airlines
Deal found 6/5![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:30 am
ORD
- CAE
1 stop6h 29m
Delta
Sun 8/25:35 am
CAE
- ORD
1 stop4h 00m
Delta
Deal found 6/5![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:17 pm
ORD
- GSP
Nonstop2h 01m
United Airlines
Mon 10/126:20 am
GSP
- ORD
Nonstop2h 02m
United Airlines
Deal found 6/4![United Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:22 pm
ORD
- CAE
1 stop4h 24m
Delta
Sun 7/55:35 am
CAE
- ORD
1 stop5h 38m
Delta
Deal found 6/6![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:30 pm
ORD
- FLO
2 stops10h 07m
American Airlines
Sat 7/112:35 pm
FLO
- ORD
1 stop4h 15m
American Airlines
Deal found 6/5![American Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:02 am
ORD
- GSP
1 stop4h 53m
Delta
Sun 8/95:46 am
GSP
- ORD
1 stop3h 58m
Delta
Deal found 6/5![Delta logo]()
$299
Last-minute flights from O'Hare Intl to South CarolinaDiscover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated June 7, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated June 7, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2512:31 pm
ORD
- CLT
1 stop10h 10m
Frontier
Tue 7/76:41 pm
CLT
- ORD
1 stop18h 34m
Frontier
Deal found 6/4![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Tue 7/71:38 pm
CLT
- ORD
2 stops31h 15m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$257
This CheapOair deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$255
This Super.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Sun 7/55:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/2![Frontier logo]()
$247
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Mon 7/68:28 pm
CLT
- ORD
1 stop27h 59m
Frontier
Deal found 6/3![Frontier logo]()
$251
This Expedia deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/4![Frontier logo]()
$250
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:45 pm
ORD
- CLT
Nonstop2h 14m
American Airlines
Sat 7/114:27 pm
CLT
- ORD
Nonstop2h 23m
American Airlines
Deal found 6/4![American Airlines logo]()
$259
This CheapOair deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:48 pm
ORD
- CLT
1 stop22h 37m
Frontier
Tue 7/76:41 pm
CLT
- ORD
1 stop18h 34m
Frontier
Deal found 6/7![Frontier logo]()
$260
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:30 am
ORD
- AGS
1 stop4h 42m
Delta
Sat 7/186:45 pm
AGS
- ORD
1 stop6h 08m
Delta
Deal found 6/7![Delta logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Wed 7/296:48 pm
CLT
- ORD
2 stops31h 01m
Frontier
Deal found 6/2![Frontier logo]()
$256
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Sat 8/15:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/7![Frontier logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Mon 8/316:40 pm
CLT
- ORD
1 stop18h 45m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$248
One-way flights from O'Hare Intl to South CarolinaSearch for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
Search for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:55 am
ORD
- SAV
1 stop9h 00m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:55 am
ORD
- GSP
1 stop23h 02m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Deal found 6/5![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:52 pm
ORD
- MYR
1 stop13h 51m
Frontier
Deal found 6/3![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:30 pm
ORD
- CHS
1 stop14h 08m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:55 am
ORD
- SAV
1 stop9h 00m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:55 am
ORD
- CLT
2 stops13h 40m
Frontier
Deal found 6/3![Frontier logo]()
$106
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:15 am
ORD
- MYR
Nonstop2h 19m
American Airlines
Deal found 6/6![American Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Deal found 6/6![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:55 am
ORD
- GSP
1 stop23h 02m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 pm
ORD
- CHS
1 stop14h 38m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:55 am
ORD
- CLT
1 stop27h 10m
Frontier
Deal found 6/5![Frontier logo]()
$111
Find flight deals from O'Hare Intl to South Carolina
Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated June 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Kiwi.com) |
One-way from | $81 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $339 |
Good round-trip deal | $279 or less |
Good one-way deal | $172 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 7/11
6:29 am-9:43 am
Nonstop2h 14m
Charlotte Douglas
Wed 7/15
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoAugusta
ORD - AGS
ORDAGS
Chicago O'Hare Intl
Sat 7/11
5:30 am-11:12 am
1 stop4h 42m
Augusta Bush Field
Sat 7/18
6:45 pm-11:53 pm
1 stop6h 08m
$261
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Wed 11/4
5:30 am-11:26 am
1 stop4h 56m
Charleston
Wed 11/11
8:20 am-12:06 pm
1 stop4h 46m
$277
ChicagoFlorence
ORD - FLO
ORDFLO
Chicago O'Hare Intl
Wed 7/15
8:00 am-2:10 pm
1 stop5h 10m
Florence
Wed 7/22
5:17 am-11:00 am
1 stop6h 43m
$279
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 8/1
1:55 pm-5:00 pm
Nonstop2h 05m
Greenville
Thu 8/6
7:40 pm-11:31 pm
1 stop4h 51m
$287
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Sat 10/10
2:25 pm-6:02 pm
Nonstop2h 37m
Charleston
Tue 10/13
3:00 pm-9:30 pm
1 stop7h 30m
$288
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Fri 7/17
1:44 pm-6:49 pm
1 stop4h 05m
Columbia Metropolitan
Sun 7/19
5:35 am-8:35 am
1 stop4h 00m
$289
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Fri 7/17
8:03 am-3:06 pm
1 stop6h 03m
Columbia Metropolitan
Mon 7/20
5:35 am-8:35 am
1 stop4h 00m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 8/21
6:40 am-12:41 pm
1 stop5h 01m
Greenville
Sun 8/23
8:49 am-12:40 pm
1 stop4h 51m
$289
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 10/15
5:30 am-10:58 am
1 stop4h 28m
Greenville
Sun 10/18
7:15 am-12:37 pm
1 stop6h 22m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from O'Hare Intl to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
ORD-SAV
ORD-GSP
ORD-CLT
ORD-MYR
ORD-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina
ORD-USSC
ORD-SAV
ORD-GSP
ORD-CLT
ORD-MYR
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $48). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to SC?
Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 7, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 23% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.
Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina
Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 7, 2026.
The most flights from ORD to USSC are scheduled on a Wednesday (23 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (16 on average).
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to South Carolina?
How far ahead should I book a flight from Chicago O'Hare Intl Airport to South Carolina?
The price you pay for your flight from Chicago O'Hare Intl Airport to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on May 30, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 7, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Overall
7.9
Comfort
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for O'Hare Intl to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from O'Hare Intl to South Carolina by cabin class
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O'Hare Intl and South Carolina flights
Browse other O'Hare Intl and South Carolina flight options. Last updated on June 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
O'Hare Intl to South Carolina flights
Consider these flights traveling from O'Hare Intl to South Carolina.
Top 3 airlines flying from O'Hare Intl to South Carolina
Discover the top 3 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$146 | Average$269 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$202 | Average$370 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$385 | FlexibilityNo cancel fee | On-time69% |