$118+ Cheap flights from O'Hare Intl (ORD) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Oct 8 — Oct 151
Round-trip
1 adult, Economy
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Find cheap flights from O'Hare Intl to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from O'Hare Intl to South CarolinaExplore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 8, 2026.
This Frontier deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:11 am -
1 stop11h 44m
Mon 9/288:50 am -
1 stop5h 40m
Deal found 9/4![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:04 am -
1 stop7h 16m
Thu 10/225:14 pm -
1 stop23h 16m
Deal found 9/8![Multiple Airlines logo]()
$240
This Expedia deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop6h 28m
Mon 10/195:38 pm -
1 stop22h 52m
Deal found 9/4![Frontier logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:11 am -
1 stop12h 53m
Wed 10/712:23 pm -
1 stop28h 07m
Deal found 9/8![Multiple Airlines logo]()
$243
This FlightHub deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:11 pm -
1 stop19h 46m
Sun 11/1511:52 am -
1 stop9h 07m
Deal found 9/4![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:11 am -
1 stop8h 04m
Wed 9/3012:23 pm -
1 stop27h 22m
Deal found 9/6![Multiple Airlines logo]()
$244
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:30 am -
1 stop4h 30m
Tue 9/2212:05 pm -
1 stop9h 24m
Deal found 9/7![Multiple Airlines logo]()
$245
This Booking.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 am -
1 stop8h 18m
Sun 9/277:54 pm -
1 stop29h 29m
Deal found 9/6![Frontier logo]()
$246
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:11 am -
1 stop11h 01m
Mon 10/58:50 am -
1 stop5h 40m
Deal found 9/7![Frontier logo]()
$249
This Frontier deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop13h 10m
Sat 9/194:51 pm -
1 stop7h 13m
Deal found 9/4![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 am -
1 stop8h 04m
Wed 10/712:23 pm -
1 stop28h 07m
Deal found 9/8![Multiple Airlines logo]()
$252
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:20 am -
1 stop6h 48m
Sun 10/412:09 pm -
1 stop10h 30m
Deal found 9/8![Frontier logo]()
$254
Best flights from O'Hare Intl to South CarolinaDiscover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
Discover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 8, 2026.
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:03 pm -
Nonstop2h 12m
Sat 10/245:30 pm -
Nonstop2h 29m
Deal found 9/3![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
1 stop5h 34m
Mon 10/53:53 pm -
1 stop6h 03m
Deal found 9/6![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:25 am -
2 stops9h 58m
Mon 9/283:18 pm -
1 stop25h 02m
Deal found 9/8![Multiple Airlines logo]()
$346
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:09 am -
Nonstop1h 59m
Sun 10/256:01 am -
Nonstop2h 21m
Deal found 9/8![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:03 pm -
Nonstop2h 12m
Mon 10/127:50 pm -
1 stop4h 42m
Deal found 9/8![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:50 am -
1 stop4h 30m
Thu 10/13:04 pm -
Nonstop2h 25m
Deal found 9/3![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/39:30 am -
1 stop4h 19m
Mon 2/87:55 pm -
1 stop4h 55m
Deal found 9/4![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:17 pm -
Nonstop2h 10m
Sun 10/119:43 am -
Nonstop2h 22m
Deal found 9/3![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:50 am -
1 stop4h 30m
Fri 9/256:45 am -
Nonstop2h 15m
Deal found 9/3![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:22 pm -
1 stop7h 13m
Tue 11/105:30 am -
1 stop6h 30m
Deal found 9/5![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:55 pm -
1 stop6h 56m
Mon 11/97:15 pm -
1 stop5h 39m
Deal found 9/7![Delta logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:09 am -
Nonstop1h 59m
Mon 10/268:33 pm -
1 stop4h 35m
Deal found 9/8![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:00 am -
Nonstop2h 27m
Wed 10/147:53 pm -
1 stop4h 39m
Deal found 9/8![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:23 pm -
1 stop4h 38m
Mon 10/126:00 am -
1 stop5h 29m
Deal found 9/5![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:27 am -
1 stop4h 35m
Sun 11/85:25 am -
1 stop4h 14m
Deal found 9/8![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:45 pm -
Nonstop2h 06m
Wed 12/306:00 am -
1 stop4h 40m
Deal found 9/6![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:29 am -
1 stop6h 40m
Sun 11/15:09 am -
1 stop4h 51m
Deal found 9/4![American Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 am -
1 stop4h 34m
Thu 11/1211:47 am -
1 stop5h 31m
Deal found 9/8![Delta logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
Nonstop2h 24m
Mon 10/1912:46 pm -
Nonstop2h 35m
Deal found 9/8![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
1 stop6h 20m
Sat 10/38:05 am -
1 stop5h 36m
Deal found 9/8![Delta logo]()
$377
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:29 am -
1 stop6h 40m
Mon 10/125:09 am -
1 stop5h 01m
Deal found 9/7![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:30 pm -
Nonstop2h 34m
Wed 11/112:52 pm -
1 stop5h 02m
Deal found 9/4![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:45 pm -
1 stop6h 12m
Sun 10/112:34 pm -
1 stop6h 17m
Deal found 9/5![American Airlines logo]()
$421
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/175:30 am -
1 stop4h 40m
Sun 12/206:59 pm -
1 stop6h 00m
Deal found 9/4![Delta logo]()
$395
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:06 pm -
1 stop4h 50m
Mon 10/126:45 am -
Nonstop2h 15m
Deal found 9/7![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:04 am -
1 stop4h 29m
Wed 11/2511:30 am -
1 stop5h 48m
Deal found 9/6![Delta logo]()
$405
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:10 pm -
Nonstop2h 23m
Tue 10/273:35 pm -
Nonstop2h 30m
Deal found 9/4![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:05 am -
1 stop5h 04m
Wed 11/255:09 am -
1 stop4h 50m
Deal found 9/6![American Airlines logo]()
$455
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:55 pm -
Nonstop2h 23m
Sun 10/46:00 am -
1 stop6h 46m
Deal found 9/8![United Airlines logo]()
$371
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:41 am -
1 stop6h 28m
Fri 11/275:09 am -
1 stop6h 51m
Deal found 9/6![American Airlines logo]()
$467
Last-minute flights from O'Hare Intl to South CarolinaDiscover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated September 8, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated September 8, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:30 am -
1 stop4h 30m
Tue 9/2212:05 pm -
1 stop9h 24m
Deal found 9/7![Multiple Airlines logo]()
$245
This Frontier deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop13h 10m
Sat 9/194:51 pm -
1 stop7h 13m
Deal found 9/4![Frontier logo]()
$251
This Frontier deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 am -
1 stop8h 18m
Mon 9/288:50 am -
1 stop5h 40m
Deal found 9/4![Frontier logo]()
$240
This Booking.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 am -
1 stop8h 18m
Sun 9/277:54 pm -
1 stop29h 29m
Deal found 9/6![Frontier logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:11 am -
1 stop8h 04m
Wed 9/3012:23 pm -
1 stop27h 22m
Deal found 9/6![Multiple Airlines logo]()
$244
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:11 am -
1 stop11h 01m
Mon 10/58:50 am -
1 stop5h 40m
Deal found 9/7![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 am -
1 stop8h 04m
Wed 10/712:23 pm -
1 stop28h 07m
Deal found 9/8![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:11 am -
1 stop12h 53m
Wed 10/712:23 pm -
1 stop28h 07m
Deal found 9/8![Multiple Airlines logo]()
$243
This Priceline deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:20 am -
1 stop6h 48m
Sun 10/412:09 pm -
1 stop10h 30m
Deal found 9/8![Frontier logo]()
$254
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:50 pm -
1 stop15h 45m
Thu 10/89:42 pm -
1 stop10h 49m
Deal found 9/5![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:04 am -
1 stop7h 16m
Thu 10/225:14 pm -
1 stop23h 16m
Deal found 9/8![Multiple Airlines logo]()
$240
This Expedia deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop6h 28m
Mon 10/195:38 pm -
1 stop22h 52m
Deal found 9/4![Frontier logo]()
$243
One-way flights from O'Hare Intl to South CarolinaSearch for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
Search for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:11 am -
1 stop9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:11 am -
1 stop8h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:00 am -
1 stop12h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:11 am -
1 stop8h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:11 am -
1 stop12h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:00 am -
1 stop23h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 am -
1 stop8h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:11 am -
1 stop24h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$129
This Priceline deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:20 am -
1 stop6h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:11 am -
1 stop12h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$130
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:50 pm -
1 stop19h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$131
This Super.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:11 am -
1 stop11h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$134
Find flight deals from O'Hare Intl to South Carolina
Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated September 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Frontier) |
One-way from | $118 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $421 |
Good round-trip deal | $279 or less |
Good one-way deal | $199 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Tue 9/29
7:28 pm-3:16 pm
2 stops18h 48m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$153
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Fri 11/27
11:18 am-7:33 pm
1 stop7h 15m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Tue 10/6
8:05 am-1:00 pm
1 stop3h 55m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Wed 10/7
6:30 am-11:35 am
1 stop4h 05m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Tue 12/29
8:05 am-3:26 pm
1 stop6h 21m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Sat 10/10
8:05 am-3:28 pm
1 stop6h 23m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$171
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Sat 3/6
1:35 pm-9:50 pm
1 stop7h 15m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Thu 10/1
1:55 pm-5:18 pm
Nonstop2h 23m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
ChicagoSavannah
ORD Chicago O'Hare Intl - SAV Savannah/Hilton Head
ORDSAV
Chicago O'Hare Intl
Wed 10/7
6:09 pm-9:48 pm
Nonstop2h 39m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
ChicagoMyrtle Beach
ORD Chicago O'Hare Intl - MYR Myrtle Beach Intl
ORDMYR
Chicago O'Hare Intl
Wed 11/11
10:32 am-6:01 pm
1 stop6h 29m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$182
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from O'Hare Intl to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
ORD-CLT
ORD-SAV
ORD-GSP
ORD-MYR
ORD-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina
ORD-USSC
ORD-CLT
ORD-SAV
ORD-GSP
ORD-MYR
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $327). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $410). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to SC?
Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 8, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 24% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.
Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina
Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 8, 2026.
The most flights from ORD to USSC are scheduled on a Monday (16 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to South Carolina?
Airfare is below average for this route at the moment.
Chicago O'Hare Intl Airport to South Carolina flights typically cost between $279 and $460 in November.The cheapest round-trip price found within the last 5 days was $273 on Multiple Airlines (Nov 7-Nov 11).
How far ahead should I book a flight from Chicago O'Hare Intl Airport to South Carolina?
The price you pay for your flight from Chicago O'Hare Intl Airport to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 8, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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O'Hare Intl and South Carolina flights
Browse other O'Hare Intl and South Carolina flight options. Last updated on September 8, 2026.
Popular flight searches
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O'Hare Intl to South Carolina flights
Consider these flights traveling from O'Hare Intl to South Carolina.
Top 3 airlines flying from O'Hare Intl to South Carolina
Discover the top 3 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$277 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$369 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$391 | FlexibilityNo cancel fee | On-time69% |