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South Carolina

$32+ Cheap flights from O'Hare Intl (ORD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Jan 2 — Jan 91
Fri 1/2
Fri 1/9
1 adult, Economy
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Cheap flight deals from O'Hare Intl to South Carolina

Cheapest flights from O'Hare Intl to South Carolina
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 3, 2025.

This Super.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
Thu 1/19:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/2$77
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:50 amORD - CLT
Nonstop2h 07mFrontier
Sun 1/113:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/2$92
This Frontier deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:50 amORD - CLT
Nonstop2h 07mFrontier
Mon 1/123:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/2$93
This Frontier deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
Thu 1/83:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/3$97
This Super.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:25 amORD - CLT
Nonstop2h 07mFrontier
Thu 12/259:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/1$101
This Frontier deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:50 amORD - CLT
Nonstop2h 07mFrontier
Thu 1/19:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/1$103
This Frontier deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amORD - CLT
Nonstop2h 07mFrontier
Fri 1/93:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/1$104
This Super.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:05 amORD - CLT
Nonstop2h 07mFrontier
Thu 1/19:27 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/1$112
This Super.com deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:50 amORD - CLT
Nonstop2h 07mFrontier
Tue 12/3010:52 amCLT - ORD
Nonstop2h 13mFrontier
Deal found 12/1$114
This Frontier deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:45 amORD - CLT
Nonstop2h 07mFrontier
Fri 1/93:45 pmCLT - ORD
Nonstop2h 22mFrontier
Deal found 12/1$118
This Cheapflightsfares deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:00 amORD - MYR
1 stop11h 48mSpirit Airlines
Thu 12/189:54 amMYR - ORD
1 stop9h 45mSpirit Airlines
Deal found 12/1$190
This Mytrip deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:00 amORD - MYR
1 stop11h 48mSpirit Airlines
Thu 12/119:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Deal found 12/1$199

Find flight deals from O'Hare Intl to South Carolina

Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated December 3, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$74
(Super.com)

One-way from

$32
(Trip.com)

Popular in

December

Cheapest in

January

Average price

$444

Good round-trip deal

$255 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
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From Chicago O'Hare Intl to South Carolina
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One-way flight from Chicago O'Hare Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($33 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to South Carolina.
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Price to beat on a one-way flight from Chicago O'Hare Intl to South Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

O'Hare Intl

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/27

6:10 pm-9:21 pm

Nonstop2h 11m

Charlotte Douglas

Mon 3/2

6:15 am-7:41 am

Nonstop2h 26m

$116

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Tue 1/6

7:17 am-10:33 am

Nonstop2h 16m

Charlotte Douglas

Sat 1/10

7:44 pm-11:39 pm

1 stop4h 55m

$137

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 2/27

2:19 pm-5:24 pm

Nonstop2h 05m

Charlotte Douglas

Tue 3/3

10:42 am-12:11 pm

Nonstop2h 29m

$169

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 2/14

11:18 am-4:04 pm

1 stop3h 46m

Charlotte Douglas

Sun 2/15

2:26 pm-7:19 pm

1 stop5h 53m

$177

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 2/21

5:25 am-10:23 am

1 stop3h 58m

Charlotte Douglas

Sun 3/1

6:00 am-9:41 am

1 stop4h 41m

$180

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 2/19

11:42 am-8:15 am

1 stop19h 33m

Myrtle Beach Intl

Mon 2/23

9:10 am-12:18 am

1 stop16h 08m

$187

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 2/19

5:53 pm-11:57 pm

1 stop5h 04m

Myrtle Beach Intl

Mon 2/23

9:10 am-6:52 pm

1 stop10h 42m

$187

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Fri 1/16

5:30 am-1:30 pm

1 stop7h 00m

Myrtle Beach Intl

Mon 1/19

10:31 am-1:40 pm

1 stop4h 09m

$201

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Fri 1/16

7:05 am-1:30 pm

1 stop5h 25m

Myrtle Beach Intl

Sun 1/18

4:00 pm-7:35 pm

1 stop4h 35m

$201

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 1/21

1:55 pm-4:52 pm

Nonstop1h 57m

Greenville

Mon 1/26

5:34 pm-6:48 pm

Nonstop2h 14m

$202

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 60 results
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Best time to book a flight from O'Hare Intl to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $60). Flying from Chicago O'Hare Intl Airport to South Carolina in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SC?

Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 3, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 29% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on November 29, 2025.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina

Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 3, 2025.

The most flights from ORD to USSC are scheduled on a Tuesday (16 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 3, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,011 reviews
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,063 reviews
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Spirit Airlines
6.3
Okay
8,156 reviews
Southwest
8.0
Very good
4,253 reviews

Food

7.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago O'Hare Intl Airport to South Carolina?

    There are many flights that can get you from Chicago O'Hare Intl Airport to South Carolina in 2h 11m. Fly via United Airlines, Delta, or Spirit Airlines to get the fastest option. Chicago O'Hare Intl Airport and South Carolina are separated by a distance of 599 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to South Carolina one-way?

    For one-way options, check prices for Volaris. According to our data, you can fly for as low as $42. Users have also found prices from $50 and $73 on Viva and Frontier, respectively.

  • What are the most popular routes from Chicago O'Hare Intl Airport to South Carolina?

    The most popular route from Chicago O'Hare Intl Airport to South Carolina is Chicago O'Hare Intl - Charlotte Douglas. You may also consider Chicago O'Hare Intl - Charleston or Chicago O'Hare Intl - Savannah/Hilton Head.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to South Carolina?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to South Carolina are Emirates (100%), Alaska Airlines (82%) and Envoy Air (78%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to South Carolina?

    Looking at all options, your cheapest flight can be booked for $139. While the most popular route (Chicago O'Hare Intl - Charlotte Douglas) can be booked for $98 on average, our data indicates $384 when flying from Chicago O'Hare Intl Airport to South Carolina.

  • Can I find deals for flights from O'Hare Intl to South Carolina that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to South Carolina.

  • Can I find deals for business class flights from O'Hare Intl to South Carolina?

    Yes. Cheapflights offers flight deals from O'Hare Intl to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $60). Flying from Chicago O'Hare Intl Airport to South Carolina in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for O'Hare Intl to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from O'Hare Intl to South Carolina

Discover the top 5 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$64Average$192FlexibilityNo cancel feeOn-time65%
DeltaCheapest$148Average$285FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$188Average$411FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$202Average$374FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$210Average$277FlexibilityNo cancel feeOn-time63%

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