$95+ Cheap flights from O'Hare Intl (ORD) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Aug 23 — Aug 301
Round-trip
1 adult, Economy
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Cheapest flights from O'Hare Intl to South CarolinaExplore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:33 am
ORD
- CHS
Nonstop2h 25m
United Airlines
Mon 8/174:38 pm
CHS
- ORD
Nonstop2h 32m
United Airlines
Deal found 7/23![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:57 pm
ORD
- CHS
Nonstop2h 21m
American Airlines
Sun 9/612:23 pm
CHS
- ORD
Nonstop2h 36m
American Airlines
Deal found 7/22![American Airlines logo]()
$242
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:10 am
ORD
- SAV
Nonstop2h 30m
United Airlines
Wed 9/93:28 pm
SAV
- ORD
1 stop7h 47m
United Airlines
Deal found 7/23![United Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:05 am
ORD
- CHS
1 stop9h 09m
Multiple Airlines
Tue 8/254:04 pm
CHS
- ORD
2 stops40h 49m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:45 am
ORD
- CHS
1 stop12h 11m
Multiple Airlines
Tue 9/159:18 am
CHS
- ORD
2 stops11h 26m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:05 am
ORD
- CHS
1 stop9h 09m
Multiple Airlines
Tue 9/83:13 pm
CHS
- ORD
1 stop8h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$246
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:10 am
ORD
- SAV
Nonstop2h 30m
United Airlines
Sun 9/69:50 am
SAV
- ORD
1 stop5h 37m
United Airlines
Deal found 7/20![United Airlines logo]()
$247
This American Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:50 pm
ORD
- CHS
Nonstop2h 24m
American Airlines
Sun 9/61:07 pm
CHS
- ORD
1 stop4h 36m
American Airlines
Deal found 7/19![American Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
ORD
- SAV
1 stop28h 50m
Multiple Airlines
Wed 8/1912:19 pm
SAV
- ORD
1 stop25h 31m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am
ORD
- SAV
Nonstop2h 30m
United Airlines
Mon 10/269:08 am
SAV
- ORD
Nonstop2h 33m
United Airlines
Deal found 7/23![United Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:45 am
ORD
- CHS
2 stops27h 46m
Multiple Airlines
Tue 10/69:18 am
CHS
- ORD
1 stop15h 37m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Sat 8/2212:19 pm
SAV
- ORD
2 stops20h 34m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$251
Best flights from O'Hare Intl to South CarolinaDiscover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from O'Hare Intl to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:10 am
ORD
- SAV
Nonstop2h 30m
United Airlines
Wed 9/93:28 pm
SAV
- ORD
1 stop7h 47m
United Airlines
Deal found 7/23![United Airlines logo]()
$243
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am
ORD
- SAV
1 stop6h 20m
Delta
Mon 10/52:55 pm
SAV
- ORD
1 stop4h 50m
Delta
Deal found 7/22![Delta logo]()
$267
This JetBlue deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:01 am
ORD
- CHS
1 stop5h 47m
JetBlue
Fri 8/281:05 pm
CHS
- ORD
1 stop7h 22m
JetBlue
Deal found 7/22![JetBlue logo]()
$295
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:18 pm
ORD
- AGS
1 stop7h 21m
American Airlines
Wed 10/216:00 am
AGS
- ORD
1 stop6h 36m
American Airlines
Deal found 7/21![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
ORD
- CHS
1 stop7h 10m
United Airlines
Mon 8/1711:40 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 7/23![United Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:45 am
ORD
- CHS
1 stop4h 28m
United Airlines
Mon 11/210:19 am
CHS
- ORD
1 stop5h 02m
United Airlines
Deal found 7/23![United Airlines logo]()
$257
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am
ORD
- CAE
1 stop6h 44m
Delta
Sun 9/203:53 pm
CAE
- ORD
1 stop6h 03m
Delta
Deal found 7/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:52 pm
ORD
- SAV
Nonstop2h 24m
United Airlines
Mon 10/56:10 am
SAV
- ORD
Nonstop2h 39m
United Airlines
Deal found 7/22![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:50 am
ORD
- CAE
1 stop4h 09m
Delta
Mon 10/2611:50 am
CAE
- ORD
1 stop6h 07m
Delta
Deal found 7/19![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:30 am
ORD
- CAE
1 stop4h 35m
Delta
Sun 11/12:00 pm
CAE
- ORD
1 stop5h 59m
Delta
Deal found 7/19![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:45 am
ORD
- FLO
1 stop6h 24m
American Airlines
Sat 10/242:34 pm
FLO
- ORD
1 stop4h 17m
American Airlines
Deal found 7/23![American Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:29 am
ORD
- CAE
Nonstop2h 14m
United Airlines
Mon 8/315:38 pm
CAE
- ORD
Nonstop2h 26m
United Airlines
Deal found 7/20![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:40 am
ORD
- CAE
1 stop5h 34m
Delta
Sun 9/275:40 am
CAE
- ORD
1 stop5h 40m
Delta
Deal found 7/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:09 pm
ORD
- CAE
Nonstop2h 19m
United Airlines
Mon 8/315:38 pm
CAE
- ORD
Nonstop2h 26m
United Airlines
Deal found 7/20![United Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:49 pm
ORD
- AGS
1 stop4h 27m
American Airlines
Wed 8/1910:18 am
AGS
- ORD
1 stop7h 30m
American Airlines
Deal found 7/20![American Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:05 am
ORD
- HHH
1 stop6h 22m
Delta
Mon 9/2812:17 pm
HHH
- ORD
1 stop5h 20m
Delta
Deal found 7/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:45 am
ORD
- SAV
1 stop4h 53m
United Airlines
Mon 8/242:10 pm
SAV
- ORD
1 stop7h 20m
United Airlines
Deal found 7/20![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:30 am
ORD
- GSP
1 stop4h 38m
Delta
Mon 10/56:25 pm
GSP
- ORD
1 stop6h 34m
Delta
Deal found 7/23![Delta logo]()
$294
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:53 pm
ORD
- CLT
Nonstop2h 01m
American Airlines
Sun 8/304:16 pm
CLT
- ORD
Nonstop2h 21m
American Airlines
Deal found 7/23![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am
ORD
- CAE
1 stop4h 39m
Delta
Sun 8/305:40 am
CAE
- ORD
1 stop4h 04m
Delta
Deal found 7/22![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:55 pm
ORD
- CLT
Nonstop2h 22m
United Airlines
Fri 9/186:01 pm
CLT
- ORD
Nonstop2h 29m
United Airlines
Deal found 7/21![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:45 am
ORD
- CAE
1 stop5h 29m
Delta
Sun 10/255:40 am
CAE
- ORD
1 stop3h 58m
Delta
Deal found 7/22![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:50 am
ORD
- CLT
Nonstop2h 18m
United Airlines
Tue 8/1810:25 am
CLT
- ORD
1 stop5h 05m
United Airlines
Deal found 7/20![United Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:49 pm
ORD
- AGS
1 stop4h 27m
American Airlines
Sun 8/912:45 pm
AGS
- ORD
1 stop5h 52m
American Airlines
Deal found 7/21![American Airlines logo]()
$451
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:00 pm
ORD
- GSP
1 stop6h 27m
Delta
Sun 10/185:40 am
GSP
- ORD
1 stop3h 58m
Delta
Deal found 7/22![Delta logo]()
$299
This KAYAK deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:00 am
ORD
- GSP
Nonstop2h 00m
American Airlines
Thu 8/1311:00 am
GSP
- ORD
1 stop7h 57m
American Airlines
Deal found 7/20![American Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:10 am
ORD
- SAV
Nonstop2h 23m
United Airlines
Tue 11/311:53 am
SAV
- ORD
Nonstop2h 33m
United Airlines
Deal found 7/21![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:40 pm
ORD
- SAV
1 stop4h 19m
Delta
Sat 9/195:00 pm
SAV
- ORD
1 stop4h 56m
Delta
Deal found 7/19![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:39 am
ORD
- CHS
Nonstop2h 25m
United Airlines
Fri 10/211:27 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 7/23![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:54 am
ORD
- HHH
1 stop4h 38m
Delta
Tue 9/812:17 pm
HHH
- ORD
1 stop7h 24m
Delta
Deal found 7/21![Delta logo]()
$299
Last-minute flights from O'Hare Intl to South CarolinaDiscover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to South Carolina. Data last updated July 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:55 pm
ORD
- SAV
Nonstop2h 24m
United Airlines
Sat 8/158:10 am
SAV
- ORD
Nonstop2h 33m
United Airlines
Deal found 7/21![United Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:05 am
ORD
- SAV
1 stop28h 50m
Multiple Airlines
Wed 8/1912:19 pm
SAV
- ORD
1 stop25h 31m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:33 am
ORD
- CHS
Nonstop2h 25m
United Airlines
Mon 8/174:38 pm
CHS
- ORD
Nonstop2h 32m
United Airlines
Deal found 7/23![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:23 am
ORD
- CHS
1 stop6h 29m
Delta
Mon 8/176:45 pm
CHS
- ORD
1 stop6h 12m
Delta
Deal found 7/22![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:40 am
ORD
- SAV
1 stop3h 57m
Delta
Tue 8/2510:23 am
SAV
- ORD
1 stop4h 46m
Delta
Deal found 7/22![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Wed 8/1912:19 pm
SAV
- ORD
1 stop25h 31m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:05 am
ORD
- CHS
1 stop9h 09m
Multiple Airlines
Tue 8/254:04 pm
CHS
- ORD
2 stops40h 49m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:56 pm
ORD
- SAV
1 stop5h 39m
United Airlines
Tue 8/253:23 pm
SAV
- ORD
1 stop7h 52m
United Airlines
Deal found 7/22![United Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Sat 8/2212:19 pm
SAV
- ORD
2 stops20h 34m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:59 pm
ORD
- CHS
1 stop13h 39m
Multiple Airlines
Tue 8/253:13 pm
CHS
- ORD
1 stop8h 55m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:05 am
ORD
- CHS
1 stop27h 59m
Multiple Airlines
Sun 8/307:47 pm
CHS
- ORD
1 stop18h 03m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$258
This United Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:10 am
ORD
- SAV
Nonstop2h 30m
United Airlines
Sun 9/69:50 am
SAV
- ORD
1 stop5h 37m
United Airlines
Deal found 7/20![United Airlines logo]()
$247
One-way flights from O'Hare Intl to South CarolinaSearch for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from O'Hare Intl to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$95
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:15 am
ORD
- MYR
Nonstop2h 19m
American Airlines
Deal found 7/22![American Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:05 am
ORD
- GSP
1 stop22h 52m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$101
This WAYA deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am
ORD
- MYR
1 stop5h 34m
Frontier
Deal found 7/21![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:45 am
ORD
- GSP
1 stop28h 43m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:45 am
ORD
- GSP
2 stops8h 38m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$105
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/205:55 pm
ORD
- MYR
1 stop4h 40m
Delta
Deal found 7/23![Delta logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:05 am
ORD
- CHS
1 stop9h 09m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:45 am
ORD
- GSP
1 stop9h 45m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:05 am
ORD
- CHS
1 stop9h 09m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:45 am
ORD
- GSP
2 stops9h 38m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$113
Find flight deals from O'Hare Intl to South Carolina
Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated July 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (United Airlines) |
One-way from | $95 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $415 |
Good round-trip deal | $289 or less |
Good one-way deal | $158 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSavannah
ORD - SAV
ORDSAV
Chicago O'Hare Intl
Thu 9/3
7:10 am-10:40 am
Nonstop2h 30m
Savannah/Hilton Head
Wed 9/9
3:28 pm-10:15 pm
1 stop7h 47m
$243
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Thu 8/13
7:00 am-3:10 pm
1 stop7h 10m
Charleston
Mon 8/17
11:40 am-1:13 pm
Nonstop2h 33m
$247
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Thu 10/29
8:45 am-2:13 pm
1 stop4h 28m
Charleston
Mon 11/2
10:19 am-2:21 pm
1 stop5h 02m
$257
ChicagoSavannah
ORD - SAV
ORDSAV
Chicago O'Hare Intl
Thu 10/1
4:52 pm-8:16 pm
Nonstop2h 24m
Savannah/Hilton Head
Mon 10/5
6:10 am-7:49 am
Nonstop2h 39m
$258
ChicagoSavannah
ORD - SAV
ORDSAV
Chicago O'Hare Intl
Thu 10/1
6:40 am-2:00 pm
1 stop6h 20m
Savannah/Hilton Head
Mon 10/5
2:55 pm-6:45 pm
1 stop4h 50m
$267
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Thu 8/27
6:29 am-9:43 am
Nonstop2h 14m
Columbia Metropolitan
Mon 8/31
5:38 pm-7:04 pm
Nonstop2h 26m
$269
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Wed 8/26
6:09 pm-9:28 pm
Nonstop2h 19m
Columbia Metropolitan
Mon 8/31
5:38 pm-7:04 pm
Nonstop2h 26m
$269
ChicagoSavannah
ORD - SAV
ORDSAV
Chicago O'Hare Intl
Thu 8/20
8:45 am-2:38 pm
1 stop4h 53m
Savannah/Hilton Head
Mon 8/24
2:10 pm-8:30 pm
1 stop7h 20m
$278
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Thu 9/17
5:30 am-1:14 pm
1 stop6h 44m
Columbia Metropolitan
Sun 9/20
3:53 pm-8:56 pm
1 stop6h 03m
$289
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Fri 10/23
9:50 am-2:59 pm
1 stop4h 09m
Columbia Metropolitan
Mon 10/26
11:50 am-4:57 pm
1 stop6h 07m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from O'Hare Intl to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
ORD-SAV
ORD-MYR
ORD-GSP
ORD-CHS
ORD-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina
ORD-USSC
ORD-SAV
ORD-MYR
ORD-GSP
ORD-CHS
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $335). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $409). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to SC?
Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 24, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 22% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.
Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina
Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 24, 2026.
The most flights from ORD to USSC are scheduled on a Tuesday (19 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (14 on average).
How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to South Carolina?
Airfare is below average for this route at the moment.
Chicago O'Hare Intl Airport to South Carolina flights typically cost between $295 and $448 in August.The cheapest round-trip price found within the last 5 days was $237 on United Airlines (Aug 13-Aug 17).
How far ahead should I book a flight from Chicago O'Hare Intl Airport to South Carolina?
The price you pay for your flight from Chicago O'Hare Intl Airport to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on July 18, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 24, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for O'Hare Intl to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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O'Hare Intl and South Carolina flights
Browse other O'Hare Intl and South Carolina flight options. Last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
O'Hare Intl to South Carolina flights
Consider these flights traveling from O'Hare Intl to South Carolina.
Top 3 airlines flying from O'Hare Intl to South Carolina
Discover the top 3 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$146 | Average$257 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$202 | Average$371 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$387 | FlexibilityNo cancel fee | On-time69% |