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$221+ Cheap flights from Des Moines to Greensboro (DSM - GSO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSO
Jun 11 — Jun 181
Thu 6/11
Thu 6/18
1 adult, Economy
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Cheap flight deals from Des Moines to Greensboro

Cheapest flights from Des Moines to Greensboro
Explore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.

This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:37 pm
DSM
-
GSO
1 stop4h 31m
American Airlines
Tue 6/307:33 pm
GSO
-
DSM
1 stop6h 02m
American Airlines
Deal found 5/7$309
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:55 am
DSM
-
GSO
1 stop6h 15m
American Airlines
Sat 5/306:45 am
GSO
-
DSM
1 stop7h 07m
American Airlines
Deal found 5/7$310
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:25 pm
DSM
-
GSO
1 stop6h 54m
Delta
Tue 6/302:19 pm
GSO
-
DSM
1 stop6h 14m
Delta
Deal found 5/11$311
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:26 am
DSM
-
GSO
1 stop6h 11m
Delta
Sat 5/306:10 am
GSO
-
DSM
1 stop4h 36m
Delta
Deal found 5/8$315
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:47 pm
DSM
-
GSO
1 stop4h 33m
Delta
Tue 8/116:39 am
GSO
-
DSM
1 stop4h 55m
Delta
Deal found 5/7$319

Find flight deals from Des Moines to Greensboro

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greensboro (GSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

One-way from

$221
(Delta)

Popular in

December

Cheapest in

November

Average price

$292
Provider with most accurate pricing for Des Moines-Greensboro/H. Point flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Greensboro/H. Point flights.
Search Deals
From Des Moines to Greensboro/H. Point
Search Deals
One-way flight from Des Moines to Greensboro/H. Point
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Greensboro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Des Moines to Greensboro that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 6/23

5:35 am-11:38 am

1 stop5h 03m

Greensboro/H. Point

Tue 6/30

9:30 am-3:57 pm

1 stop7h 27m

$311

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 6/24

2:25 pm-10:19 pm

1 stop6h 54m

Greensboro/H. Point

Tue 6/30

9:30 am-3:57 pm

1 stop7h 27m

$311

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Mon 8/3

6:35 pm-11:59 pm

1 stop4h 24m

Greensboro/H. Point

Sat 8/8

7:01 am-10:34 am

1 stop4h 33m

$315
Quickest round-trip

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 5/27

6:41 pm-11:57 pm

1 stop4h 16m

Greensboro/H. Point

Sat 5/30

7:52 am-11:19 am

1 stop4h 27m

$315

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sat 6/27

1:47 pm-9:51 pm

1 stop7h 04m

Greensboro/H. Point

Tue 6/30

6:33 pm-12:35 am

2 stops7h 02m

$316

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Wed 8/5

11:22 am-7:12 pm

1 stop6h 50m

Greensboro/H. Point

Mon 8/10

12:27 pm-5:48 pm

1 stop6h 21m

$319

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 8/6

5:40 am-1:53 pm

1 stop7h 13m

Greensboro/H. Point

Tue 8/11

6:39 am-10:34 am

1 stop4h 55m

$319

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Mon 8/3

6:35 pm-11:59 pm

1 stop4h 24m

Greensboro/H. Point

Sun 8/9

6:39 am-10:34 am

1 stop4h 55m

$319
Cheapest one-way
Quickest one-way

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sun 5/24

5:27 am-12:16 pm

1 stop5h 49m

$221

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Sun 5/24

5:50 am-5:00 pm

2 stops10h 10m

$266

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/10

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Greensboro

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greensboro in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Greensboro flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Greensboro flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Greensboro flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Greensboro flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greensboro flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Greensboro

Have a flexible travel schedule? Discover the best time to fly to Greensboro from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Greensboro

What is the cheapest month to book a flight from Des Moines to Greensboro?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $248). Flying from Des Moines to Greensboro in December is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Greensboro?

Reviews of airlines servicing Greensboro

Get insights into the airlines that provide service to Greensboro. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greensboro. Reviews last updated May 12, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Greensboro have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,451 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,451 reviews
Delta
7.9
Good
8,451 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,667 reviews
Delta
7.9
Good
8,451 reviews

Boarding

8.1

Overall

7.9

Crew

8.5

Entertainment

7.8

Food

7.2

Comfort

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Greensboro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Greensboro?

    Departing from Des Moines to Greensboro will take you 5h 03m. The distance between Des Moines and Greensboro is about 827 mi.

  • What are the cheapest airlines flying from Des Moines to Greensboro round-trip?

    According to our current data, American Airlines ($248), and Delta ($248) offers the cheapest pricing from Des Moines to Greensboro. American Airlines is currently priced 26% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Greensboro that include hotel bookings?

    Yes. In addition to deals on Des Moines to Greensboro flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Greensboro?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Greensboro.

  • Can I find deals for business class flights from Des Moines to Greensboro?

    Yes. Cheapflights offers flight deals from Des Moines to Greensboro by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Greensboro?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Greensboro (average of $248). Flying from Des Moines to Greensboro in December is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greensboro?

Book flights to Greensboro if you plan to visit one of these locations
Asheboro
Kernersville
High Point

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Top 2 airlines flying from Des Moines to Greensboro

Discover the top 2 airlines that operate flights from Des Moines to Greensboro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$299FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$283FlexibilityNo cancel feeOn-timeN/A

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