$269+ Cheap flights from Des Moines to Greensboro (DSM - GSO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSO
Sep 13 — Sep 201
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Greensboro with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Greensboro
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Best
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One-way
Cheapest flights from Des Moines to GreensboroExplore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
Explore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:11 pm -
1 stop6h 44m
Wed 9/1611:21 am -
1 stop6h 58m
Deal found 8/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am -
1 stop7h 13m
Tue 9/15:30 am -
1 stop6h 13m
Deal found 8/13![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:54 pm -
1 stop4h 05m
Mon 10/127:05 pm -
1 stop4h 28m
Deal found 8/13![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:55 am -
1 stop4h 51m
Mon 9/76:29 am -
1 stop6h 55m
Deal found 8/10![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:30 pm -
1 stop4h 02m
Wed 9/165:20 pm -
2 stops7h 21m
Deal found 8/11![American Airlines logo]()
$432
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:10 pm -
1 stop4h 41m
Tue 9/11:43 pm -
2 stops6h 36m
Deal found 8/13![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:26 am -
2 stops8h 28m
Mon 10/126:13 pm -
1 stop5h 54m
Deal found 8/13![American Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:00 am -
1 stop12h 13m
Wed 10/286:15 am -
1 stop17h 35m
Deal found 8/13![United Airlines logo]()
$623
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:26 am -
2 stops8h 28m
Mon 10/126:13 pm -
1 stop5h 54m
Deal found 8/13![American Airlines logo]()
$630
Best flights from Des Moines to GreensboroDiscover carefully curated flight deals from Des Moines to Greensboro that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
Discover carefully curated flight deals from Des Moines to Greensboro that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:11 pm -
1 stop6h 44m
Thu 9/176:00 am -
1 stop4h 38m
Deal found 8/9![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:55 am -
1 stop4h 51m
Mon 9/76:29 am -
1 stop6h 55m
Deal found 8/11![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/276:15 am -
1 stop13h 42m
Sat 1/308:00 am -
1 stop10h 33m
Deal found 8/11![United Airlines logo]()
$623
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:11 pm -
1 stop6h 44m
Wed 9/1611:21 am -
1 stop6h 58m
Deal found 8/11![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:39 am -
1 stop6h 33m
Mon 10/127:05 pm -
1 stop4h 28m
Deal found 8/13![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:54 pm -
1 stop4h 05m
Mon 10/127:05 pm -
1 stop4h 28m
Deal found 8/13![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:30 am -
2 stops7h 26m
Thu 9/176:43 pm -
1 stop6h 21m
Deal found 8/9![American Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:00 am -
1 stop12h 13m
Wed 10/286:15 am -
1 stop17h 35m
Deal found 8/13![United Airlines logo]()
$623
Last-minute flights from Des Moines to GreensboroDiscover last-minute flight deals from Des Moines to Greensboro. Data last updated August 14, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Greensboro. Data last updated August 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am -
1 stop7h 13m
Tue 9/15:30 am -
1 stop6h 13m
Deal found 8/13![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:10 pm -
1 stop4h 41m
Tue 9/11:43 pm -
2 stops6h 36m
Deal found 8/13![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:55 am -
1 stop4h 51m
Mon 9/76:29 am -
1 stop6h 55m
Deal found 8/10![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:15 am -
2 stops16h 27m
Mon 9/76:00 am -
2 stops12h 28m
Deal found 8/13![United Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:20 pm -
2 stops21h 54m
Wed 9/166:00 am -
2 stops12h 28m
Deal found 8/13![United Airlines logo]()
$700
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:11 pm -
1 stop6h 44m
Wed 9/1611:21 am -
1 stop6h 58m
Deal found 8/11![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:30 pm -
1 stop4h 02m
Wed 9/165:20 pm -
2 stops7h 21m
Deal found 8/11![American Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:13 am -
2 stops13h 28m
Wed 9/166:00 am -
2 stops12h 28m
Deal found 8/11![United Airlines logo]()
$673
One-way flights from Des Moines to GreensboroSearch for one-way flight options from Des Moines to Greensboro. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
Search for one-way flight options from Des Moines to Greensboro. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
1 stop7h 20m
Deal found 8/11![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:11 pm -
2 stops26h 23m
Deal found 8/11![United Airlines logo]()
$468
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:15 pm -
2 stops7h 29m
Deal found 8/10![United Airlines logo]()
$704
Find flight deals from Des Moines to Greensboro
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greensboro (GSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Delta) |
One-way from | $269 (American Airlines) |
Popular in | September |
Cheapest in | November |
Average price | $283 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Greensboro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Des Moines to Greensboro that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 9/10
4:11 pm-11:55 pm
1 stop6h 44m
Greensboro/H. Point
Thu 9/17
6:00 am-9:38 am
1 stop4h 38m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 9/10
4:11 pm-11:55 pm
1 stop6h 44m
Greensboro/H. Point
Wed 9/16
11:21 am-5:19 pm
1 stop6h 58m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Sat 10/10
5:39 am-1:12 pm
1 stop6h 33m
Greensboro/H. Point
Mon 10/12
7:05 pm-10:33 pm
1 stop4h 28m
$364
Quickest round-trip
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 10/9
6:54 pm-11:59 pm
1 stop4h 05m
Greensboro/H. Point
Mon 10/12
7:05 pm-10:33 pm
1 stop4h 28m
$364
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 9/3
6:55 am-12:46 pm
1 stop4h 51m
Greensboro/H. Point
Mon 9/7
6:29 am-12:24 pm
1 stop6h 55m
$398
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 9/10
6:30 am-2:56 pm
2 stops7h 26m
Greensboro/H. Point
Thu 9/17
6:43 pm-12:04 am
1 stop6h 21m
$570
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Wed 1/27
6:15 am-8:57 pm
1 stop13h 42m
Greensboro/H. Point
Sat 1/30
8:00 am-5:33 pm
1 stop10h 33m
$623
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Sat 10/24
8:00 am-9:13 pm
1 stop12h 13m
Greensboro/H. Point
Wed 10/28
6:15 am-10:50 pm
1 stop17h 35m
$623
Cheapest one-way
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 9/25
3:11 pm-6:34 pm
2 stops26h 23m
$468
Quickest one-way
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Sun 11/1
3:15 pm-11:44 pm
2 stops7h 29m
$704
Sorted by cheapest first
Compare providers for flights from Des Moines to Greensboro
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greensboro in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Greensboro flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Greensboro flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Greensboro flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Greensboro flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greensboro flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Greensboro
Have a flexible travel schedule? Discover the best time to fly to Greensboro from Des Moines with our price prediction graph.
DSM-GSO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Greensboro
Reviews of airlines servicing Greensboro
Get insights into the airlines that provide service to Greensboro. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greensboro. Reviews last updated August 14, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Greensboro have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Greensboro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greensboro?
Book flights to Greensboro if you plan to visit one of these locationsAsheboro
Kernersville
High Point
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Other flights to Greensboro
Explore flights to Greensboro departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Des Moines and Greensboro flights
Browse other Des Moines and Greensboro flight options. Last updated on August 14, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Greensboro
Discover the top 2 airlines that operate flights from Des Moines to Greensboro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$319 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$283 | FlexibilityNo cancel fee | On-timeN/A |