$220+ Cheap flights from Des Moines to Greensboro (DSM - GSO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSO
Oct 6 — Oct 131
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Greensboro with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Greensboro
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Cheapest flights from Des Moines to GreensboroExplore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
Explore the most affordable flight options available from Des Moines to Greensboro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:54 pm -
1 stop4h 05m
Sun 10/185:25 am -
1 stop6h 17m
Deal found 8/31![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:34 pm -
1 stop5h 23m
Sat 9/191:14 pm -
1 stop4h 35m
Deal found 9/1![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:54 pm -
1 stop4h 01m
Mon 9/285:30 am -
1 stop6h 16m
Deal found 9/5![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:30 am -
1 stop6h 27m
Tue 12/156:15 am -
2 stops10h 45m
Deal found 9/3![United Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:11 pm -
1 stop6h 44m
Sun 9/138:10 am -
1 stop6h 39m
Deal found 9/3![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
1 stop7h 20m
Thu 10/85:05 am -
1 stop6h 37m
Deal found 9/1![American Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am -
1 stop6h 38m
Mon 9/286:43 pm -
1 stop6h 21m
Deal found 9/3![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:32 am -
1 stop4h 42m
Sun 9/136:00 am -
2 stops7h 16m
Deal found 9/3![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:33 am -
1 stop5h 45m
Mon 9/77:44 am -
1 stop5h 40m
Deal found 8/31![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:25 am -
2 stops8h 31m
Sun 11/87:36 pm -
1 stop5h 50m
Deal found 9/3![American Airlines logo]()
$432
Best flights from Des Moines to GreensboroDiscover carefully curated flight deals from Des Moines to Greensboro that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
Discover carefully curated flight deals from Des Moines to Greensboro that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:54 pm -
1 stop4h 05m
Tue 10/132:55 pm -
1 stop4h 14m
Deal found 8/31![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am -
3 stops10h 48m
Sun 9/136:00 am -
2 stops9h 20m
Deal found 9/3![United Airlines logo]()
$505
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:54 pm -
1 stop4h 05m
Sun 10/185:25 am -
1 stop6h 17m
Deal found 8/31![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:54 pm -
1 stop4h 05m
Sun 10/187:00 am -
1 stop4h 42m
Deal found 8/31![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:54 pm -
1 stop4h 05m
Tue 10/205:25 am -
1 stop6h 17m
Deal found 8/31![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:54 pm -
1 stop4h 01m
Mon 9/285:30 am -
1 stop6h 16m
Deal found 9/5![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
2 stops7h 14m
Mon 9/282:55 pm -
2 stops9h 40m
Deal found 9/4![United Airlines logo]()
$527
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:11 pm -
1 stop6h 44m
Sun 9/138:10 am -
1 stop6h 39m
Deal found 9/3![Delta logo]()
$365
Last-minute flights from Des Moines to GreensboroDiscover last-minute flight deals from Des Moines to Greensboro. Data last updated September 6, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Greensboro. Data last updated September 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:33 am -
1 stop5h 45m
Mon 9/77:44 am -
1 stop5h 40m
Deal found 8/31![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:11 pm -
1 stop6h 44m
Sun 9/138:10 am -
1 stop6h 39m
Deal found 9/3![Delta logo]()
$365
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:32 am -
1 stop4h 42m
Sun 9/136:00 am -
2 stops7h 16m
Deal found 9/3![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:34 pm -
1 stop5h 23m
Sat 9/191:14 pm -
1 stop4h 35m
Deal found 9/1![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
2 stops8h 30m
Sat 9/197:04 pm -
1 stop6h 00m
Deal found 9/1![American Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:54 pm -
1 stop4h 01m
Mon 9/285:30 am -
1 stop6h 16m
Deal found 9/5![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:35 am -
1 stop6h 38m
Mon 9/286:43 pm -
1 stop6h 21m
Deal found 9/3![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
1 stop7h 20m
Thu 10/85:05 am -
1 stop6h 37m
Deal found 9/1![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:54 pm -
1 stop4h 05m
Sun 10/185:25 am -
1 stop6h 17m
Deal found 8/31![Delta logo]()
$319
One-way flights from Des Moines to GreensboroSearch for one-way flight options from Des Moines to Greensboro. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
Search for one-way flight options from Des Moines to Greensboro. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am -
2 stops25h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$220
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:30 pm -
1 stop6h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:34 pm -
1 stop6h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
2 stops7h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$279
Find flight deals from Des Moines to Greensboro
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greensboro (GSO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Delta) |
One-way from | $220 (Kiwi.com) |
Popular in | September |
Cheapest in | November |
Average price | $577 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Greensboro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
Use the filters below to find and compare flights from Des Moines to Greensboro that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 10/1
8:10 am-10:54 am
2 stops25h 44m
Greensboro/H. Point
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$220
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 10/2
1:30 pm-9:10 pm
1 stop6h 40m
Greensboro/H. Point
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$269
Quickest round-trip
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 10/1
2:34 pm-10:10 pm
1 stop6h 36m
Greensboro/H. Point
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$274
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 10/2
6:00 am-2:14 pm
2 stops7h 14m
Greensboro/H. Point
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$279
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 10/8
6:54 pm-11:59 pm
1 stop4h 05m
Greensboro/H. Point
Tue 10/13
2:55 pm-6:09 pm
1 stop4h 14m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 10/15
6:54 pm-11:59 pm
1 stop4h 05m
Greensboro/H. Point
Sun 10/18
5:25 am-10:42 am
1 stop6h 17m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 10/16
6:54 pm-11:59 pm
1 stop4h 05m
Greensboro/H. Point
Sun 10/18
7:00 am-10:42 am
1 stop4h 42m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 10/16
6:54 pm-11:59 pm
1 stop4h 05m
Greensboro/H. Point
Tue 10/20
5:25 am-10:42 am
1 stop6h 17m
$319
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Thu 9/24
6:54 pm-11:55 pm
1 stop4h 01m
Greensboro/H. Point
Mon 9/28
5:30 am-10:46 am
1 stop6h 16m
$354
Des MoinesGreensboro
DSM Des Moines - GSO Greensboro/H. Point
DSMGSO
Des Moines
Fri 9/11
4:11 pm-11:55 pm
1 stop6h 44m
Greensboro/H. Point
Sun 9/13
8:10 am-1:49 pm
1 stop6h 39m
$365
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Greensboro
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greensboro in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Greensboro flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Greensboro flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Greensboro flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Greensboro flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greensboro flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Greensboro
Have a flexible travel schedule? Discover the best time to fly to Greensboro from Des Moines with our price prediction graph.
DSM-GSO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Greensboro
Reviews of airlines servicing Greensboro
Get insights into the airlines that provide service to Greensboro. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greensboro. Reviews last updated September 6, 2026.
See what other customers who have flown with Delta and American Airlines from Des Moines to Greensboro have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Boarding
8.1
Overall
7.8
Entertainment
7.8
Comfort
7.8
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Greensboro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greensboro?
Book flights to Greensboro if you plan to visit one of these locationsAsheboro
Kernersville
High Point
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Greensboro
Explore flights to Greensboro departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 6, 2026.
Des Moines and Greensboro flights
Browse other Des Moines and Greensboro flight options. Last updated on September 6, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Greensboro
Discover the top 2 airlines that operate flights from Des Moines to Greensboro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$310 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$368 | FlexibilityNo cancel fee | On-time71% |