HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$159+ Cheap flights from Greensboro to Des Moines (GSO - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
GSO — DSM
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greensboro to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greensboro to Des Moines

Cheapest flights from Greensboro to Des Moines
Explore the most affordable flight options available from Greensboro to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:20 pm
GSO
-
DSM
1 stop6h 18m
Delta
Mon 6/156:39 pm
DSM
-
GSO
1 stop4h 20m
Delta
Deal found 4/22$329
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:18 am
GSO
-
DSM
2 stops6h 13m
American Airlines
Thu 5/215:16 am
DSM
-
GSO
2 stops7h 45m
American Airlines
Deal found 4/22$398
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:15 am
GSO
-
DSM
1 stop5h 22m
United Airlines
Tue 5/1210:02 am
DSM
-
GSO
1 stop5h 56m
United Airlines
Deal found 4/23$419
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:31 pm
GSO
-
DSM
1 stop5h 56m
American Airlines
Tue 5/55:01 pm
DSM
-
GSO
1 stop4h 53m
American Airlines
Deal found 4/23$423
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:49 am
GSO
-
DSM
1 stop14h 13m
Multiple Airlines
Fri 8/1410:06 pm
DSM
-
GSO
2 stops56h 53m
Multiple Airlines
Deal found 4/23$425
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:56 am
GSO
-
DSM
1 stop14h 41m
Allegiant Air
Sun 6/216:00 am
DSM
-
GSO
2 stops25h 06m
Allegiant Air
Deal found 4/25$434
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
GSO
-
DSM
1 stop4h 44m
Delta
Sun 6/216:39 pm
DSM
-
GSO
1 stop4h 20m
Delta
Deal found 4/25$439
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:10 pm
GSO
-
DSM
1 stop5h 35m
Delta
Sun 5/36:31 pm
DSM
-
GSO
1 stop4h 24m
Delta
Deal found 4/26$441
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
GSO
-
DSM
1 stop7h 34m
American Airlines
Fri 8/145:00 am
DSM
-
GSO
1 stop5h 02m
American Airlines
Deal found 4/23$443
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:15 am
GSO
-
DSM
1 stop5h 22m
United Airlines
Sun 5/311:40 am
DSM
-
GSO
2 stops11h 03m
United Airlines
Deal found 4/26$446

Find flight deals from Greensboro to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Greensboro (GSO) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(Delta)

One-way from

$159
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$338
Provider with most accurate pricing for Greensboro/H. Point-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greensboro/H. Point-Des Moines flights.
Search Deals
From Greensboro/H. Point to Des Moines
Search Deals
One-way flight from Greensboro/H. Point to Des Moines
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greensboro to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Greensboro to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Fri 6/12

2:20 pm-7:38 pm

1 stop6h 18m

Des Moines

Mon 6/15

6:39 pm-11:59 pm

1 stop4h 20m

$329

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Fri 5/8

6:15 am-10:37 am

1 stop5h 22m

Des Moines

Tue 5/12

10:02 am-4:58 pm

1 stop5h 56m

$419

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Mon 6/15

8:56 am-10:37 pm

1 stop14h 41m

Des Moines

Sun 6/21

6:00 am-8:06 am

2 stops25h 06m

$434
Quickest round-trip

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Mon 6/15

6:00 am-9:44 am

1 stop4h 44m

Des Moines

Sun 6/21

6:39 pm-11:59 pm

1 stop4h 20m

$439

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/14

8:25 pm-11:49 pm

1 stop4h 24m

Des Moines

Thu 5/21

5:16 am-2:01 pm

2 stops7h 45m

$452

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Tue 5/12

12:16 pm-11:24 pm

2 stops12h 08m

Des Moines

Sat 5/16

10:02 am-4:58 pm

1 stop5h 56m

$466

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/14

4:07 pm-10:32 pm

1 stop7h 25m

Des Moines

Thu 5/21

6:41 pm-11:57 pm

1 stop4h 16m

$507

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/7

8:25 pm-11:49 pm

1 stop4h 24m

Des Moines

Fri 5/8

8:03 pm-11:09 am

1 stop14h 06m

$558

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 5/7

9:28 am-2:24 pm

1 stop5h 56m

Des Moines

Fri 5/8

11:31 am-12:24 am

2 stops11h 53m

$572
Cheapest one-way

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Fri 8/7

8:49 am-10:02 pm

1 stop14h 13m

$159

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Greensboro to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greensboro to Des Moines in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greensboro-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greensboro-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greensboro-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greensboro-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greensboro-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greensboro to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Greensboro with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greensboro to Des Moines

How much does it cost to fly round-trip from Greensboro to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 27, 2026.
See what other customers who have flown with Delta and American Airlines from Greensboro to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,463 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,463 reviews
Delta
7.9
Good
8,463 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,668 reviews
Delta
7.9
Good
8,463 reviews

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greensboro to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greensboro to Des Moines?

    For as low as $419, Delta can have you in Des Moines from Greensboro in 5h 22m. The distance between Greensboro and Des Moines is about 827 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greensboro to Des Moines round-trip?

    American Airlines, at $242, was found to be the cheapest airline from Greensboro to Des Moines. An alternate airline flying to your destination would be Delta. You may be able to fly from Greensboro to Des Moines for 27% less than the average price by searching for these airlines.

  • Can I find deals for flights from Greensboro to Des Moines that include hotel bookings?

    Yes. In addition to deals on Greensboro to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greensboro to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greensboro to Des Moines.

  • Can I find deals for business class flights from Greensboro to Des Moines?

    Yes. Cheapflights offers flight deals from Greensboro to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Greensboro to Des Moines

Discover the top 2 airlines that operate flights from Greensboro to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$242Average$328FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$289FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.