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Des Moines

$113+ Cheap flights from Charlotte to Des Moines (CLT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
May 22 — May 291
Fri 5/22
Fri 5/29
1 adult, Economy
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Find cheap flights from Charlotte to Des Moines with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Charlotte Douglas to Des Moines are usually found in September or August, booked 58 days in advance, depart on a Wednesday or Sunday and return on a Wednesday

Cheap flight deals from Charlotte to Des Moines

Cheapest flights from Charlotte to Des Moines
Explore the most affordable flight options available from Charlotte to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:16 pm
CLT
-
DSM
2 stops31h 11m
Multiple Airlines
Mon 6/84:07 pm
DSM
-
CLT
1 stop18h 58m
Multiple Airlines
Deal found 4/20$226
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:00 pm
CLT
-
DSM
1 stop10h 31m
Multiple Airlines
Thu 5/284:41 pm
DSM
-
CLT
1 stop16h 22m
Multiple Airlines
Deal found 4/20$236
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:35 pm
CLT
-
DSM
1 stop22h 40m
Multiple Airlines
Mon 5/186:48 pm
DSM
-
CLT
2 stops18h 23m
Multiple Airlines
Deal found 4/22$265
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:07 pm
CLT
-
DSM
2 stops26h 50m
Multiple Airlines
Sun 5/244:41 pm
DSM
-
CLT
1 stop16h 22m
Multiple Airlines
Deal found 4/19$266
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:35 am
CLT
-
DSM
1 stop4h 50m
Southwest
Wed 5/273:15 pm
DSM
-
CLT
1 stop4h 40m
Southwest
Deal found 4/20$267
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:29 pm
CLT
-
DSM
1 stop11h 58m
Multiple Airlines
Sun 6/75:02 pm
DSM
-
CLT
1 stop16h 01m
Multiple Airlines
Deal found 4/18$275
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
CLT
-
DSM
1 stop10h 15m
Multiple Airlines
Sun 5/177:45 am
DSM
-
CLT
1 stop27h 20m
Multiple Airlines
Deal found 4/19$279
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:58 pm
CLT
-
DSM
2 stops44h 01m
Multiple Airlines
Mon 5/253:57 pm
DSM
-
CLT
1 stop19h 08m
Multiple Airlines
Deal found 4/20$297
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:16 pm
CLT
-
DSM
2 stops32h 15m
Multiple Airlines
Wed 5/272:16 pm
DSM
-
CLT
1 stop27h 02m
Multiple Airlines
Deal found 4/20$300

Find flight deals from Charlotte to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$226
(Kiwi.com)

One-way from

$113
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$448

Good round-trip deal

$441 or less
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
Search Deals
From Charlotte Douglas to Des Moines
Search Deals
One-way flight from Charlotte Douglas to Des Moines
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Charlotte Douglas to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 5/20

7:35 am-11:25 am

1 stop4h 50m

Des Moines

Wed 5/27

3:15 pm-8:55 pm

1 stop4h 40m

$283

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 8/11

6:35 pm-9:55 pm

1 stop4h 20m

Des Moines

Sun 8/16

5:40 am-11:45 am

1 stop5h 05m

$363

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Sat 5/23

8:10 am-11:30 am

1 stop4h 20m

Des Moines

Sat 5/30

5:35 am-11:35 am

1 stop5h 00m

$366

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 9/9

10:23 am-5:02 pm

2 stops7h 39m

Des Moines

Wed 9/30

6:45 pm-12:50 am

1 stop5h 05m

$412

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 9/9

1:30 pm-9:55 pm

2 stops9h 25m

Des Moines

Wed 9/30

6:10 am-5:55 pm

2 stops10h 45m

$421
Quickest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 8/11

6:00 am-9:19 am

1 stop4h 19m

Des Moines

Sun 8/16

6:20 am-12:03 pm

1 stop4h 43m

$441

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 5/19

11:20 am-10:10 pm

2 stops11h 50m

Des Moines

Tue 5/26

5:30 am-12:55 pm

2 stops6h 25m

$448

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 6/12

2:22 pm-5:54 pm

1 stop4h 32m

Des Moines

Sun 6/14

10:23 am-3:58 pm

1 stop4h 35m

$471

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Thu 5/21

6:59 am-11:08 am

1 stop5h 09m

Des Moines

Sun 5/24

4:25 pm-11:55 pm

1 stop6h 30m

$471

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 5/18

6:15 am-1:10 pm

2 stops7h 55m

Des Moines

Mon 5/25

5:25 am-6:20 pm

2 stops11h 55m

$490

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Charlotte to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Des Moines in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charlotte-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charlotte-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charlotte-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charlotte-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charlotte to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Des Moines

How far ahead should I book a flight from Charlotte to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Charlotte to Des Moines. Price data was last updated on April 17, 2026.

To ensure you get the cheapest price possible for a flight from Charlotte to Des Moines, you should look to book at least 58 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Charlotte to Des Moines?

Currently, September is the cheapest month in which you can book a flight from Charlotte to Des Moines (average of $349). Flying from Charlotte to Des Moines in November is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to DSM?

Find hourly flight availability from Charlotte to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2026.

One of the essential ways to save on airfare from Charlotte to Des Moines is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 13% on airfare.

How much does it cost to fly round-trip from Charlotte to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 22, 2026.
Get a feel of what it's like to fly with American Airlines from Charlotte to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,647 reviews

Boarding

7.5

Crew

7.9

Overall

7.1

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,647 reviews
American Airlines
7.1
Good
11,647 reviews

Boarding

7.5

Crew

7.9

Overall

7.1

Comfort

7.2

Entertainment

6.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Charlotte to Des Moines?

    If you wish to fly to Des Moines from Charlotte, then you need to book flights from Charlotte Douglas to Des Moines. There is 1 flight from Douglas (CLT) to Des Moines (DSM) per day to choose from. Flights to Des Moines from Douglas are available from 1 airline, which means you should have some options if you want to compare airfare deals. 2h 25m is how long a nonstop flight from Charlotte to Des Moines typically takes.

  • How popular is this Charlotte to Des Moines flight route?

    Flights from Charlotte Douglas to Des Moines have been viewed 2 times in the past calendar month.

  • How long is the flight from Charlotte to Des Moines?

    For as low as $283, Southwest can have you in Des Moines from Charlotte in 4h 50m. Charlotte and Des Moines are separated by a distance of 813 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Charlotte to Des Moines round-trip?

    Currently priced at $349, American Airlines will fly you from Charlotte to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. American Airlines is currently priced 19% below the average price you’ll pay for this route.

  • What are the cheapest flights from Charlotte to Des Moines?

    Looking for the cheapest flight from Charlotte to Des Moines? While on average our users pay $448, our data indicates the cheapest price to be $391. The most popular route (Charlotte Douglas - Des Moines), is priced around $226.

  • Can I find deals for flights from Charlotte to Des Moines that include hotel bookings?

    Yes. In addition to deals on Charlotte to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Des Moines.

  • Can I find deals for business class flights from Charlotte to Des Moines?

    Yes. Cheapflights offers flight deals from Charlotte to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from Charlotte to Des Moines (average of $349). Flying from Charlotte to Des Moines in November is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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Top airline flying from Charlotte to Des Moines

Discover the top airline that operate flights from Charlotte to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$349Average$449FlexibilityNo cancel feeOn-time71%

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