$168+ Cheap flights from Knoxville to Des Moines (TYS - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
Jul 22 — Jul 291

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Cheap flight deals from Knoxville to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 17, 2024.

Popular in

February

Cheapest in

January

Average price

$272

Round-trip from

$168
(CheapOair)
High demand for flights, 46% potential price rise
Best time to find cheap flights, 35% potential price drop
Average for round-trip flights in July 2024
From Knoxville McGhee Tyson to Des Moines

What is the cheapest day to fly round-trip from Knoxville to Des Moines?

Leaving on a Wednesday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 65% on the overall cost on flights from Knoxville to Des Moines.

What is the cheapest month to fly from Knoxville to Des Moines?

January can be a great time to fly to Des Moines from Knoxville with a flight ticket averaging about $388. Cheapflights users have found deals in the month of January for as cheap as $234. The most expensive prices can be found in the month of February.

What is the cheapest time of day to fly from TYS to DSM?

When flying from Knoxville to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 26% versus a flight in the afternoon.

Cheap Knoxville to Des Moines flights in July & August 2024

Find cheap flight options from Knoxville to Des Moines specifically for the months of July and August 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,731,402 searches. Prices were last updated on July 17, 2024.
Scroll through some of the best deals on flights from Knoxville to Des Moines in 2024. Check back in a little while for more flight options.
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/166:04 pmTYS - DSM
1 stop5h 59mAmerican Airlines
Sun 8/183:07 pmDSM - TYS
1 stop5h 29mAmerican Airlines
Deal found 7/16$248
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2711:05 amTYS - DSM
1 stop4h 16mAmerican Airlines
Fri 8/304:02 pmDSM - TYS
1 stop7h 46mAmerican Airlines
Deal found 7/16$278
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2711:05 amTYS - DSM
2 stops7h 31mAmerican Airlines
Fri 8/304:02 pmDSM - TYS
1 stop7h 46mAmerican Airlines
Deal found 7/16$283
This mytrip.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/167:00 amTYS - DSM
1 stop9h 02mMultiple Airlines
Sun 8/182:00 pmDSM - TYS
2 stops28h 14mMultiple Airlines
Deal found 7/16$341
This mytrip.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/167:00 amTYS - DSM
1 stop9h 02mMultiple Airlines
Sun 8/182:00 pmDSM - TYS
3 stops31h 46mMultiple Airlines
Deal found 7/16$376
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/279:25 amTYS - DSM
2 stops13h 17mUnited Airlines
Fri 8/306:45 pmDSM - TYS
2 stops14h 41mUnited Airlines
Deal found 7/16$528

Knoxville to Des Moines 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and Des Moines in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,731,402 searches. Data last updated July 17, 2024.
Scroll through some of the best deals on flights from Knoxville to Des Moines in 2024. Check back in a little while for more flight options.
This CheapOair deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/185:42 pmTYS - DSM
1 stop27h 33mFrontier
Sun 10/209:15 pmDSM - TYS
1 stop19h 02mFrontier
Deal found 7/16$168
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/166:04 pmTYS - DSM
1 stop5h 59mAmerican Airlines
Sun 8/183:07 pmDSM - TYS
1 stop5h 29mAmerican Airlines
Deal found 7/16$248
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/156:20 pmTYS - DSM
1 stop5h 34mAmerican Airlines
Mon 10/217:58 amDSM - TYS
1 stop6h 44mAmerican Airlines
Deal found 7/17$258
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2711:05 amTYS - DSM
1 stop4h 16mAmerican Airlines
Fri 8/304:02 pmDSM - TYS
1 stop7h 46mAmerican Airlines
Deal found 7/16$278
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2711:05 amTYS - DSM
2 stops7h 31mAmerican Airlines
Fri 8/304:02 pmDSM - TYS
1 stop7h 46mAmerican Airlines
Deal found 7/16$283
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/154:10 pmTYS - DSM
2 stops7h 44mAmerican Airlines
Mon 10/215:53 amDSM - TYS
1 stop4h 07mAmerican Airlines
Deal found 7/17$293
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/84:29 pmTYS - DSM
1 stop7h 10mAmerican Airlines
Mon 11/113:29 pmDSM - TYS
2 stops7h 05mAmerican Airlines
Deal found 7/17$308
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/176:20 pmTYS - DSM
1 stop5h 34mAmerican Airlines
Mon 10/217:58 amDSM - TYS
1 stop6h 44mAmerican Airlines
Deal found 7/16$333
This mytrip.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure mytrip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/167:00 amTYS - DSM
1 stop9h 02mMultiple Airlines
Sun 8/182:00 pmDSM - TYS
2 stops28h 14mMultiple Airlines
Deal found 7/16$341

Find flights from Knoxville to Des Moines within your budget

Customize your flight search to find flights from Knoxville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,731,402 searches. Data last updated July 17, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$168 - $398

Route

Depart

Return

Price

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 10/18

1 stop27h 33m

Des Moines

Sun 10/20

1 stop19h 02m

$168

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 8/16

1 stop5h 59m

Des Moines

Sun 8/18

1 stop5h 29m

$248

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 11/8

1 stop7h 10m

Des Moines

Mon 11/11

1 stop4h 39m

$258

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Tue 8/27

1 stop4h 16m

Des Moines

Fri 8/30

1 stop7h 46m

$278

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Tue 8/27

2 stops7h 31m

Des Moines

Fri 8/30

1 stop7h 46m

$283

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 8/16

1 stop9h 02m

Des Moines

Sun 8/18

2 stops28h 14m

$341

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 8/16

1 stop9h 02m

Des Moines

Sun 8/18

3 stops31h 46m

$376

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 10/17

2 stops9h 36m

Des Moines

Mon 10/21

1 stop6h 13m

$393

Knoxville McGhee TysonDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Tue 10/15

2 stops9h 36m

Des Moines

Mon 10/21

2 stops7h 12m

$398

Flights are sorted by cheapest first

Deals found on 7/16

What is the cheapest day to fly from Knoxville to Des Moines?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Des Moines. Price data was last updated on July 14, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Knoxville to Des Moines flight should consider departing on Thursday mornings when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Best time to book a flight from Knoxville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Temperature and rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature and rainfall totals by month.

DSM

Temperature

23 - 77 °F

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 17, 2024.
To help decide which airline to fly from Knoxville to Des Moines, see what other customers have to say about United Airlines and American Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
7.4
Good
10,000 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.2

Reviews

1 / 10

More comfort and free, fast Wi-Fi would always be appreciated.

7.4
Good
10,000 reviews
7.4
Good
10,000 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.2

Reviews

1 / 10

More comfort and free, fast Wi-Fi would always be appreciated.

7.3
Good
10,000 reviews
7.4
Good
10,000 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.2

Reviews

1 / 10

More comfort and free, fast Wi-Fi would always be appreciated.

6.2
Okay
3,859 reviews
7.4
Good
10,000 reviews

Boarding

7.7

Overall

7.4

Entertainment

7.1

Crew

8.1

Food

6.7

Comfort

7.2

Reviews

1 / 10

More comfort and free, fast Wi-Fi would always be appreciated.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find flights from Knoxville to Des Moines for under $200 on Cheapflights?

    Yes, there are multiple flights from Knoxville to Des Moines for under $200. The cheapest flight booked recently is on Frontier for just $168, but on average you can expect to pay $385.

  • What are the cheapest airlines flying from Knoxville to Des Moines round-trip?

    Cheapflights users have booked flights from Knoxville to Des Moines round-trip from $168. Other airlines that can offer you cheap pricing are American Airlines, from $248, and United Airlines, from $393. Users have found that Frontier is 56% cheaper than the other options available to this destination.

  • What does TYS to DSM mean?

    These are just IATA (International Air Transport Association) codes. They are used in aviation to identify and differentiate airports. That’s why a Knoxville McGhee Tyson Airport to Des Moines Airport flight would often be abbreviated as a TYS to DSM flight.

  • Can I find deals for flights from Knoxville to Des Moines that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to Des Moines flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to Des Moines with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to Des Moines flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to Des Moines that include hotel bookings?

    Yes. In addition to deals on Knoxville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Des Moines.

  • Can I find deals for business class flights from Knoxville to Des Moines?

    Yes. Cheapflights offers flight deals from Knoxville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to Des Moines that allow pets onboard?

    Many airlines flying from Knoxville to Des Moines offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to Des Moines?

    Yes, you can often find last-minute deals on Knoxville to Des Moines flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to Des Moines flight deals updated?

    The Knoxville to Des Moines flight deals you see on this page were last updated on 7/17.

  • What are the most popular airlines that fly from Knoxville to Des Moines?

  • What is the cheapest month to book a flight from Knoxville to Des Moines?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Des Moines (average of $323). Flying from Knoxville to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Des Moines

Discover the top 4 airlines that operate flights from Knoxville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,731,402 searches. Data last updated July 17, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$227Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$247Average$381FlexibilityNo cancel feeOn-time71%
Allegiant AirCheapest$272Average$330FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$312Average$415FlexibilityNo cancel feeOn-time69%

Search flights from Knoxville to Des Moines by cabin class

Find flights from Knoxville to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
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