$121+ Cheap flights from Knoxville (TYS) to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
May 19 — May 261
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to IowaExplore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- OMA
1 stop19h 57m
Multiple Airlines
Sat 5/238:19 pm
OMA
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:40 pm
TYS
- DSM
1 stop7h 26m
Allegiant Air
Mon 5/42:59 pm
DSM
- TYS
1 stop22h 59m
Allegiant Air
Deal found 4/15![Allegiant Air logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:31 pm
TYS
- OMA
1 stop18h 00m
Allegiant Air
Mon 5/116:01 pm
OMA
- TYS
1 stop14h 39m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:38 pm
TYS
- DSM
1 stop6h 49m
Allegiant Air
Sun 7/265:54 pm
DSM
- TYS
1 stop23h 20m
Allegiant Air
Deal found 4/14![Allegiant Air logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- OMA
1 stop19h 57m
Multiple Airlines
Sat 5/308:19 pm
OMA
- TYS
2 stops21h 18m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:02 pm
TYS
- DSM
2 stops33h 45m
Multiple Airlines
Sat 6/274:22 pm
DSM
- TYS
1 stop5h 33m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$290
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:50 pm
TYS
- OMA
1 stop8h 55m
Southwest
Wed 5/206:10 am
OMA
- TYS
1 stop10h 00m
Southwest
Deal found 4/17![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:33 pm
TYS
- DSM
1 stop7h 26m
American Airlines
Sat 6/271:33 pm
DSM
- TYS
1 stop5h 37m
American Airlines
Deal found 4/14![American Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:38 pm
TYS
- DSM
1 stop6h 49m
Multiple Airlines
Sun 7/264:57 pm
DSM
- TYS
2 stops24h 33m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:40 pm
TYS
- DSM
1 stop7h 26m
Multiple Airlines
Mon 5/46:33 pm
DSM
- TYS
2 stops39h 03m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:48 pm
TYS
- MLI
1 stop4h 06m
American Airlines
Tue 5/264:24 pm
MLI
- TYS
1 stop4h 34m
American Airlines
Deal found 4/14![American Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:00 am
TYS
- OMA
2 stops7h 43m
American Airlines
Mon 5/115:07 pm
OMA
- TYS
1 stop5h 48m
American Airlines
Deal found 4/16![American Airlines logo]()
$316
Best flights from Knoxville to IowaDiscover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
Discover carefully curated flight deals from Knoxville to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 19, 2026.
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:50 pm
TYS
- OMA
1 stop8h 55m
Southwest
Wed 5/205:30 am
OMA
- TYS
2 stops10h 40m
Southwest
Deal found 4/17![Southwest logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:38 pm
TYS
- DSM
1 stop6h 49m
Multiple Airlines
Sun 7/264:57 pm
DSM
- TYS
2 stops24h 33m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:48 pm
TYS
- MLI
1 stop4h 06m
American Airlines
Tue 5/264:24 pm
MLI
- TYS
1 stop4h 34m
American Airlines
Deal found 4/14![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:30 am
TYS
- MLI
1 stop5h 56m
Delta
Sat 9/511:00 am
MLI
- TYS
1 stop6h 17m
Delta
Deal found 4/17![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/301:54 pm
TYS
- MLI
1 stop3h 54m
United Airlines
Sun 5/313:47 pm
MLI
- TYS
1 stop4h 09m
United Airlines
Deal found 4/18![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/151:43 pm
TYS
- DSM
1 stop9h 50m
Allegiant Air
Sun 5/177:45 am
DSM
- TYS
1 stop12h 05m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$354
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:33 pm
TYS
- MLI
1 stop6h 57m
American Airlines
Tue 6/24:45 pm
MLI
- TYS
1 stop6h 11m
American Airlines
Deal found 4/15![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:02 pm
TYS
- MLI
1 stop4h 21m
United Airlines
Mon 6/12:31 pm
MLI
- TYS
1 stop5h 25m
United Airlines
Deal found 4/18![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:40 am
TYS
- MLI
1 stop5h 40m
Delta
Tue 6/25:17 pm
MLI
- TYS
1 stop5h 44m
Delta
Deal found 4/17![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:45 pm
TYS
- DSM
2 stops11h 00m
Southwest
Sat 6/275:10 am
DSM
- TYS
2 stops7h 55m
Southwest
Deal found 4/14![Southwest logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:34 pm
TYS
- DSM
1 stop19h 56m
Allegiant Air
Sat 6/204:22 pm
DSM
- TYS
1 stop5h 33m
Allegiant Air
Deal found 4/14![Allegiant Air logo]()
$381
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:45 am
TYS
- OMA
1 stop6h 35m
Delta
Mon 9/282:00 pm
OMA
- TYS
1 stop6h 28m
Delta
Deal found 4/15![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:20 am
TYS
- OMA
1 stop4h 56m
United Airlines
Mon 7/66:25 pm
OMA
- TYS
1 stop5h 10m
United Airlines
Deal found 4/17![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:35 pm
TYS
- OMA
2 stops11h 20m
Southwest
Sat 8/111:00 am
OMA
- TYS
1 stop7h 35m
Southwest
Deal found 4/17![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:40 am
TYS
- OMA
1 stop5h 29m
Delta
Sun 6/76:33 pm
OMA
- TYS
1 stop4h 21m
Delta
Deal found 4/18![Delta logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Tue 5/55:40 am
LSE
- TYS
1 stop4h 38m
American Airlines
Deal found 4/16![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:40 am
TYS
- OMA
2 stops9h 20m
Southwest
Sun 6/710:40 am
OMA
- TYS
2 stops9h 35m
Southwest
Deal found 4/17![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:35 pm
TYS
- OMA
2 stops11h 20m
Southwest
Sun 8/210:40 am
OMA
- TYS
2 stops9h 35m
Southwest
Deal found 4/14![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:25 pm
TYS
- DSM
2 stops8h 10m
United Airlines
Wed 5/63:20 pm
DSM
- TYS
1 stop4h 25m
United Airlines
Deal found 4/17![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/316:40 am
TYS
- OMA
2 stops9h 20m
Southwest
Mon 8/36:15 am
OMA
- TYS
2 stops8h 30m
Southwest
Deal found 4/14![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:00 am
TYS
- OMA
2 stops12h 56m
United Airlines
Mon 9/286:29 pm
OMA
- TYS
1 stop5h 01m
United Airlines
Deal found 4/14![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:05 pm
TYS
- OMA
1 stop7h 55m
Southwest
Sun 9/136:15 am
OMA
- TYS
1 stop6h 45m
Southwest
Deal found 4/17![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:30 am
TYS
- DSM
1 stop4h 57m
United Airlines
Sun 6/2811:18 am
DSM
- TYS
1 stop4h 54m
United Airlines
Deal found 4/14![United Airlines logo]()
$498
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:40 am
TYS
- OMA
2 stops9h 20m
Southwest
Sat 6/2011:00 am
OMA
- TYS
1 stop7h 35m
Southwest
Deal found 4/14![Southwest logo]()
$428
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:40 am
TYS
- DSM
2 stops16h 40m
Southwest
Sat 6/205:10 am
DSM
- TYS
2 stops7h 55m
Southwest
Deal found 4/14![Southwest logo]()
$432
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
TYS
- DSM
2 stops7h 50m
Southwest
Wed 5/65:30 am
DSM
- TYS
2 stops10h 40m
Southwest
Deal found 4/17![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:35 pm
TYS
- DSM
2 stops11h 55m
Southwest
Sun 7/265:10 am
DSM
- TYS
2 stops5h 55m
Southwest
Deal found 4/14![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:15 pm
TYS
- DSM
2 stops11h 50m
Southwest
Sun 5/175:20 am
DSM
- TYS
2 stops14h 45m
Southwest
Deal found 4/18![Southwest logo]()
$469
Last-minute flights from Knoxville to IowaDiscover last-minute flight deals from Knoxville to Iowa. Data last updated April 19, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Iowa. Data last updated April 19, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:40 pm
TYS
- DSM
1 stop7h 26m
Allegiant Air
Mon 5/42:59 pm
DSM
- TYS
1 stop22h 59m
Allegiant Air
Deal found 4/15![Allegiant Air logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:40 pm
TYS
- DSM
1 stop7h 26m
Multiple Airlines
Mon 5/46:33 pm
DSM
- TYS
2 stops39h 03m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:31 pm
TYS
- OMA
1 stop18h 00m
Allegiant Air
Mon 5/46:01 pm
OMA
- TYS
1 stop14h 39m
Allegiant Air
Deal found 4/15![Allegiant Air logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/74:31 pm
TYS
- OMA
1 stop18h 00m
Allegiant Air
Mon 5/116:01 pm
OMA
- TYS
1 stop14h 39m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$268
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:00 am
TYS
- OMA
2 stops7h 43m
American Airlines
Mon 5/115:07 pm
OMA
- TYS
1 stop5h 48m
American Airlines
Deal found 4/16![American Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:04 am
TYS
- OMA
1 stop7h 51m
American Airlines
Wed 5/132:50 pm
OMA
- TYS
1 stop6h 35m
American Airlines
Deal found 4/17![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1912:50 pm
TYS
- OMA
1 stop8h 55m
Southwest
Wed 5/206:10 am
OMA
- TYS
1 stop10h 00m
Southwest
Deal found 4/17![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:48 pm
TYS
- MLI
1 stop4h 06m
American Airlines
Tue 5/264:24 pm
MLI
- TYS
1 stop4h 34m
American Airlines
Deal found 4/14![American Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- OMA
1 stop19h 57m
Multiple Airlines
Sat 5/238:19 pm
OMA
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- OMA
1 stop19h 57m
Multiple Airlines
Sat 5/308:19 pm
OMA
- TYS
2 stops21h 18m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:40 am
TYS
- MLI
1 stop5h 40m
Delta
Tue 6/25:17 pm
MLI
- TYS
1 stop5h 44m
Delta
Deal found 4/17![Delta logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:33 pm
TYS
- MLI
1 stop6h 57m
American Airlines
Tue 6/24:45 pm
MLI
- TYS
1 stop6h 11m
American Airlines
Deal found 4/17![American Airlines logo]()
$343
One-way flights from Knoxville to IowaSearch for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
Search for one-way flight options from Knoxville to Iowa. Find affordable one-way fares based on user searches. Data last updated April 19, 2026.
This Trip.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/264:28 pm
TYS
- OMA
1 stop28h 45m
Frontier
Deal found 4/17![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- OMA
1 stop19h 57m
Allegiant Air
Deal found 4/18![Allegiant Air logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:17 pm
TYS
- DSM
1 stop24h 27m
Allegiant Air
Deal found 4/16![Allegiant Air logo]()
$151
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:50 pm
TYS
- OMA
2 stops10h 30m
Southwest
Deal found 4/18![Southwest logo]()
$154
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:01 pm
TYS
- OMA
1 stop6h 30m
United Airlines
Deal found 4/14![United Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:00 pm
TYS
- MLI
1 stop25h 02m
Allegiant Air
Deal found 4/14![Allegiant Air logo]()
$168
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:26 pm
TYS
- OMA
1 stop6h 31m
American Airlines
Deal found 4/16![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:35 am
TYS
- DSM
2 stops7h 35m
Southwest
Deal found 4/16![Southwest logo]()
$194
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:25 am
TYS
- OMA
2 stops8h 45m
Southwest
Deal found 4/15![Southwest logo]()
$194
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:40 am
TYS
- DSM
1 stop4h 33m
Delta
Deal found 4/14![Delta logo]()
$199
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:30 am
TYS
- DSM
1 stop4h 52m
United Airlines
Deal found 4/16![United Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 pm
TYS
- DSM
3 stops44h 56m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$226
Find flight deals from Knoxville to Iowa
Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated April 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (Kiwi.com) |
One-way from | $97 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $404 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
Use the filters below to find and compare flights from Knoxville to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleOmaha
TYS - OMA
TYSOMA
Knoxville McGhee Tyson
Tue 5/19
12:50 pm-8:45 pm
1 stop8h 55m
Omaha Eppley Airfield
Wed 5/20
5:30 am-5:10 pm
2 stops10h 40m
$301
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Thu 7/23
3:38 pm-9:27 pm
1 stop6h 49m
Des Moines
Sun 7/26
4:57 pm-6:30 pm
2 stops24h 33m
$307
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Tue 5/19
8:48 pm-11:54 pm
1 stop4h 06m
Moline Quad-City
Tue 5/26
4:24 pm-9:58 pm
1 stop4h 34m
$310
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Wed 9/2
5:30 am-10:26 am
1 stop5h 56m
Moline Quad-City
Sat 9/5
11:00 am-6:17 pm
1 stop6h 17m
$329
Quickest round-trip
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Sat 5/30
1:54 pm-4:48 pm
1 stop3h 54m
Moline Quad-City
Sun 5/31
3:47 pm-8:56 pm
1 stop4h 09m
$329
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Tue 5/26
5:33 pm-11:30 pm
1 stop6h 57m
Moline Quad-City
Tue 6/2
4:45 pm-11:56 pm
1 stop6h 11m
$329
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Sat 5/30
6:02 pm-9:23 pm
1 stop4h 21m
Moline Quad-City
Mon 6/1
2:31 pm-8:56 pm
1 stop5h 25m
$329
KnoxvilleMoline
TYS - MLI
TYSMLI
Knoxville McGhee Tyson
Tue 5/26
5:40 am-10:20 am
1 stop5h 40m
Moline Quad-City
Tue 6/2
5:17 pm-12:01 am
1 stop5h 44m
$329
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Fri 5/15
1:43 pm-10:33 pm
1 stop9h 50m
Des Moines
Sun 5/17
7:45 am-8:50 pm
1 stop12h 05m
$354
KnoxvilleDes Moines
TYS - DSM
TYSDSM
Knoxville McGhee Tyson
Wed 6/24
12:45 pm-10:45 pm
2 stops11h 00m
Des Moines
Sat 6/27
5:10 am-2:05 pm
2 stops7h 55m
$354
Showing 1-10 of 49 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
TYS-OMA
TYS-DSM
TYS-MLI
TYS-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Iowa
TYS-USIA
TYS-OMA
TYS-DSM
TYS-MLI
TYS-LSE
What is the cheapest month to book a flight from Knoxville to Iowa?
Currently, September is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $197). Flying from Knoxville to Iowa in March is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to Iowa?
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 19, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Knoxville to Iowa to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.9
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Comfort
7.9
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Comfort
7.9
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Comfort
7.9
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Iowa
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Complete your trip
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Knoxville and Iowa flights
Browse other Knoxville and Iowa flight options. Last updated on April 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Iowa flights
Consider these flights traveling from Knoxville to Iowa.
Top 3 airlines flying from Knoxville to Iowa
Discover the top 3 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$366 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$338 | FlexibilityNo cancel fee | On-timeN/A |