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$111+ Cheap flights from Knoxville (TYS) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DSM
3월 23 — 3월 301
일 3/23
일 3/30
1 adult, Economy
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Cheap flight deals from Knoxville to Iowa

Keep the following information in mind while searching for Knoxville to Iowa flight deals. Data was last updated 3월 18, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$111
(Mytrip)

Popular in

November

Cheapest in

August

Average price

$331
Provider with most accurate pricing for Knoxville McGhee Tyson-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Des Moines flights.
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From Knoxville McGhee Tyson to Iowa
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One-way flight from Knoxville McGhee Tyson to Iowa
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Highest demand for flights based on searches. 12% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Knoxville to Iowa

Cheapest flights from Knoxville to Iowa
Explore the most affordable flight options available from Knoxville to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3월 18, 2025.

This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 8/58:31 pmTYS - OMA
1 stop4h 49mAmerican Airlines
토 8/91:58 pmOMA - TYS
1 stop6h 37mAmerican Airlines
Deal found 3/17$199
This Mytrip deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 4/1811:13 amTYS - DSM
1 stop12h 08mAllegiant Air
일 4/207:47 pmDSM - TYS
1 stop17h 40mAllegiant Air
Deal found 3/17$232
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 7/316:05 pmTYS - OMA
1 stop5h 58mDelta
화 8/56:30 pmOMA - TYS
1 stop4h 17mDelta
Deal found 3/17$233
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 8/55:45 amTYS - OMA
2 stops9h 39mUnited Airlines
토 8/92:57 pmOMA - TYS
1 stop7h 22mUnited Airlines
Deal found 3/17$234
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 4/305:15 amTYS - DSM
1 stop7h 06mAmerican Airlines
월 5/55:27 pmDSM - TYS
1 stop5h 31mAmerican Airlines
Deal found 3/17$249
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 4/55:25 pmTYS - MLI
1 stop5h 10mUnited Airlines
금 4/115:25 pmMLI - TYS
1 stop3h 57mUnited Airlines
Deal found 3/17$254
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 4/111:31 amTYS - DSM
1 stop8h 38mDelta
화 4/85:59 pmDSM - TYS
1 stop4h 07mDelta
Deal found 3/18$254
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 4/51:00 pmTYS - MLI
2 stops9h 23mAmerican Airlines
금 4/113:24 pmMLI - TYS
1 stop7h 31mAmerican Airlines
Deal found 3/17$259
This Mytrip deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 3/268:00 amTYS - OMA
1 stop26h 29mAllegiant Air
월 3/316:06 pmOMA - TYS
1 stop22h 34mAllegiant Air
Deal found 3/16$273
This Mytrip deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 3/291:10 pmTYS - DSM
1 stop8h 33mMultiple Airlines
월 3/311:32 pmDSM - TYS
2 stops32h 59mMultiple Airlines
Deal found 3/18$319
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 8/55:45 amTYS - DSM
2 stops9h 57mUnited Airlines
토 8/93:38 pmDSM - TYS
1 stop6h 02mUnited Airlines
Deal found 3/17$324
This Mytrip deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 4/107:15 amTYS - OMA
3 stops28h 33mMultiple Airlines
일 4/135:49 pmOMA - TYS
1 stop25h 50mMultiple Airlines
Deal found 3/18$391

Find flights from Knoxville to Iowa within your budget

Customize your flight search to find flights from Knoxville to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 3월 18, 2025.

Fly from

Knoxville

Fly to

Iowa

Route

Depart

Return

Price

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

화 8/5

8:31 pm-12:20 am

1 stop4h 49m

Omaha Eppley Airfield

토 8/9

1:58 pm-9:35 pm

1 stop6h 37m

$199

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

금 4/18

11:13 am-10:21 pm

1 stop12h 08m

Des Moines

일 4/20

7:47 pm-2:27 pm

1 stop17h 40m

$232

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

목 7/31

6:05 pm-11:03 pm

1 stop5h 58m

Omaha Eppley Airfield

화 8/5

6:30 pm-11:47 pm

1 stop4h 17m

$233

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

화 8/5

5:45 am-2:24 pm

2 stops9h 39m

Omaha Eppley Airfield

토 8/9

2:57 pm-11:19 pm

1 stop7h 22m

$234

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

수 4/30

5:15 am-11:21 am

1 stop7h 06m

Des Moines

월 5/5

5:27 pm-11:58 pm

1 stop5h 31m

$249

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

토 4/5

5:25 pm-9:35 pm

1 stop5h 10m

Moline Quad-City

금 4/11

5:25 pm-10:22 pm

1 stop3h 57m

$254

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

화 4/1

11:31 am-7:09 pm

1 stop8h 38m

Des Moines

화 4/8

5:59 pm-11:06 pm

1 stop4h 07m

$254

KnoxvilleMoline

TYS - MLI

TYSMLI

Knoxville McGhee Tyson

토 4/5

1:00 pm-9:23 pm

2 stops9h 23m

Moline Quad-City

금 4/11

3:24 pm-11:55 pm

1 stop7h 31m

$259

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

토 3/29

1:10 pm-8:43 pm

1 stop8h 33m

Des Moines

월 3/31

1:32 pm-11:31 pm

2 stops32h 59m

$319

KnoxvilleOmaha

TYS - OMA

TYSOMA

Knoxville McGhee Tyson

목 5/15

12:01 pm-12:08 pm

1 stop25h 07m

Omaha Eppley Airfield

일 5/18

4:41 pm-9:39 pm

1 stop27h 58m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 19 results
1
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Best time to book a flight from Knoxville to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Iowa

Get recent, data-driven insights about flights from Knoxville to Iowa including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Iowa?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $336). Flying from Knoxville to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IA?

Find hourly flight availability from Knoxville to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 3월 18, 2025.

When flying from Knoxville to Iowa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated 3월 18, 2025.
Read through reviews of airlines operating flights from Knoxville to Iowa, such as Delta, United Airlines and Allegiant Air. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,908 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,908 reviews
Delta
8.0
Very good
7,908 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,611 reviews
Delta
8.0
Very good
7,908 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
731 reviews
Delta
8.0
Very good
7,908 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,908 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Iowa?

    If you book a flight to Iowa from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Knoxville to Iowa one-way?

    $111 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $176 and $181, respectively.

  • What are the most popular routes from Knoxville to Iowa?

    The most popular route from Knoxville to Iowa is Knoxville McGhee Tyson - Omaha Eppley Airfield. You may also consider Knoxville McGhee Tyson - Des Moines or Knoxville McGhee Tyson - La Crosse.

  • Can I find deals for flights from Knoxville to Iowa that include hotel bookings?

    Yes. In addition to deals on Knoxville to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Iowa.

  • Can I find deals for business class flights from Knoxville to Iowa?

    Yes. Cheapflights offers flight deals from Knoxville to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Iowa (average of $336). Flying from Knoxville to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Iowa

Discover the top 3 airlines that operate flights from Knoxville to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 3월 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$212Average$259FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$238Average$322FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$393FlexibilityNo cancel feeOn-time69%
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