$132+ Cheap flights from Des Moines (DSM) to North Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to North CarolinaExplore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:45 pm -
1 stop18h 15m
Wed 12/96:44 pm -
1 stop23h 02m
Deal found 10/22![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
1 stop17h 58m
Thu 12/38:54 am -
1 stop8h 52m
Deal found 10/25![Multiple Airlines logo]()
$263
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:52 pm -
1 stop4h 32m
Thu 11/126:00 am -
1 stop5h 19m
Deal found 10/21![Delta logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:25 pm -
1 stop9h 29m
Thu 11/127:00 am -
1 stop9h 25m
Deal found 10/24![Allegiant Air logo]()
$270
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops8h 15m
Tue 11/171:10 pm -
1 stop5h 18m
Deal found 10/22![United Airlines logo]()
$272
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
2 stops10h 40m
Sat 12/512:55 pm -
2 stops7h 45m
Deal found 10/22![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
1 stop24h 11m
Tue 11/35:26 pm -
1 stop19h 30m
Deal found 10/21![Multiple Airlines logo]()
$283
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:05 am -
1 stop6h 39m
Fri 11/205:24 pm -
1 stop5h 31m
Deal found 10/22![United Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:05 pm -
1 stop6h 57m
Sat 12/57:04 pm -
1 stop5h 26m
Deal found 10/21![American Airlines logo]()
$305
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 am -
1 stop5h 07m
Wed 11/1110:39 am -
2 stops7h 49m
Deal found 10/21![United Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:20 pm -
1 stop4h 57m
Sat 12/512:15 pm -
2 stops12h 00m
Deal found 10/21![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/243:25 pm -
1 stop5h 00m
Wed 1/65:50 pm -
1 stop4h 45m
Deal found 10/22![Southwest logo]()
$310
Best flights from Des Moines to North CarolinaDiscover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:29 pm -
1 stop5h 13m
Wed 11/116:00 am -
1 stop5h 19m
Deal found 10/21![Delta logo]()
$267
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 am -
1 stop5h 07m
Wed 11/1110:39 am -
2 stops7h 49m
Deal found 10/21![United Airlines logo]()
$308
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:40 am -
3 stops13h 45m
Wed 11/115:40 am -
1 stop9h 35m
Deal found 10/21![Southwest logo]()
$315
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/255:30 am -
1 stop4h 34m
Wed 12/308:23 pm -
1 stop4h 35m
Deal found 10/25![American Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
2 stops23h 51m
Sun 12/69:21 am -
1 stop8h 25m
Deal found 10/22![Multiple Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:55 am -
2 stops10h 15m
Mon 1/111:25 pm -
2 stops9h 05m
Deal found 10/21![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:29 pm -
1 stop4h 12m
Mon 11/235:20 am -
1 stop6h 24m
Deal found 10/21![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:00 am -
1 stop7h 35m
Mon 1/114:48 pm -
1 stop6h 42m
Deal found 10/24![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:31 pm -
1 stop6h 51m
Mon 12/147:04 pm -
1 stop5h 26m
Deal found 10/22![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops8h 40m
Fri 11/201:45 pm -
1 stop10h 20m
Deal found 10/22![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:11 pm -
1 stop4h 05m
Tue 12/296:30 am -
1 stop5h 23m
Deal found 10/24![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:05 am -
2 stops7h 14m
Wed 11/255:40 pm -
1 stop5h 15m
Deal found 10/21![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:09 am -
1 stop6h 44m
Wed 11/115:59 pm -
1 stop7h 27m
Deal found 10/23![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:53 pm -
1 stop6h 15m
Tue 12/226:00 am -
1 stop6h 56m
Deal found 10/25![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:00 am -
1 stop6h 57m
Fri 11/276:15 am -
1 stop5h 17m
Deal found 10/22![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops10h 40m
Tue 12/86:50 pm -
1 stop4h 15m
Deal found 10/23![Southwest logo]()
$376
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:15 pm -
1 stop4h 49m
Fri 3/126:00 am -
1 stop5h 18m
Deal found 10/21![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:30 am -
1 stop7h 56m
Wed 11/113:25 pm -
1 stop9h 17m
Deal found 10/23![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/210:55 am -
1 stop6h 18m
Mon 3/156:00 am -
1 stop5h 20m
Deal found 10/21![Delta logo]()
$352
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:15 pm -
1 stop5h 15m
Sat 11/76:30 am -
1 stop6h 50m
Deal found 10/24![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops7h 25m
Mon 11/2311:30 am -
2 stops11h 35m
Deal found 10/21![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:52 pm -
1 stop4h 06m
Wed 11/254:59 pm -
1 stop6h 36m
Deal found 10/21![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop4h 41m
Tue 12/13:03 pm -
2 stops8h 57m
Deal found 10/25![American Airlines logo]()
$517
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:52 pm -
1 stop4h 06m
Mon 11/237:00 am -
1 stop4h 44m
Deal found 10/24![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:05 am -
1 stop5h 19m
Wed 11/115:28 pm -
1 stop5h 27m
Deal found 10/23![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops10h 40m
Thu 11/266:00 am -
2 stops12h 15m
Deal found 10/21![Southwest logo]()
$464
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:17 pm -
1 stop7h 07m
Sun 11/155:40 am -
1 stop5h 04m
Deal found 10/24![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:58 pm -
2 stops8h 53m
Tue 11/248:01 pm -
1 stop5h 25m
Deal found 10/22![American Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:05 am -
2 stops7h 14m
Fri 11/276:15 am -
1 stop5h 17m
Deal found 10/26![United Airlines logo]()
$444
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 am -
2 stops11h 45m
Wed 11/2512:55 pm -
2 stops10h 40m
Deal found 10/21![Southwest logo]()
$491
Last-minute flights from Des Moines to North CarolinaDiscover last-minute flight deals from Des Moines to North Carolina. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to North Carolina. Data last updated October 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop24h 10m
Wed 10/2812:00 pm -
1 stop27h 42m
Deal found 10/22![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:00 am -
1 stop24h 11m
Tue 11/35:26 pm -
1 stop19h 30m
Deal found 10/21![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:25 pm -
1 stop9h 29m
Thu 11/127:00 am -
1 stop9h 25m
Deal found 10/24![Allegiant Air logo]()
$270
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:29 pm -
1 stop5h 13m
Wed 11/116:00 am -
1 stop5h 19m
Deal found 10/21![Delta logo]()
$267
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 am -
1 stop5h 07m
Wed 11/1110:39 am -
2 stops7h 49m
Deal found 10/21![United Airlines logo]()
$308
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops15h 35m
Thu 11/128:55 pm -
2 stops15h 35m
Deal found 10/21![Southwest logo]()
$315
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:40 am -
3 stops13h 45m
Wed 11/116:25 am -
2 stops15h 25m
Deal found 10/21![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:55 am -
2 stops8h 07m
Sun 11/156:30 am -
1 stop5h 02m
Deal found 10/22![United Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops8h 15m
Tue 11/171:10 pm -
1 stop5h 18m
Deal found 10/22![United Airlines logo]()
$272
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:05 am -
1 stop6h 39m
Fri 11/205:24 pm -
1 stop5h 31m
Deal found 10/22![United Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
1 stop17h 58m
Thu 12/38:54 am -
1 stop8h 52m
Deal found 10/25![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
1 stop17h 58m
Sun 12/68:59 am -
2 stops25h 51m
Deal found 10/25![Multiple Airlines logo]()
$320
One-way flights from Des Moines to North CarolinaSearch for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:17 pm -
1 stop25h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$132
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:35 am -
1 stop6h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$134
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/157:00 am -
2 stops9h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/296:00 am -
1 stop26h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$141
This CheapOair deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:26 pm -
1 stop21h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Frontier logo]()
$151
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/183:30 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$156
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:40 am -
2 stops11h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:35 am -
2 stops35h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$180
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:55 am -
1 stop6h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$188
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/279:25 am -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:15 am -
1 stop22h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:40 pm -
3 stops43h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$226
Find flight deals from Des Moines to North Carolina
Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $251 (Kiwi.com) |
One-way from | $132 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $495 |
Good round-trip deal | $441 or less |
Good one-way deal | $243 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Wed 1/27
10:55 am-6:13 pm
1 stop6h 18m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$134
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Tue 12/15
11:35 am-6:53 pm
1 stop6h 18m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$134
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Tue 12/15
7:00 am-5:40 pm
2 stops9h 40m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$139
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Wed 11/18
6:00 am-5:40 pm
2 stops10h 40m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$161
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Thu 12/17
6:40 am-7:25 pm
2 stops11h 45m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$174
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Mon 1/4
7:35 am-7:54 pm
2 stops35h 19m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$180
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Sun 11/22
9:55 am-5:41 pm
1 stop6h 46m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$188
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Wed 1/27
9:25 am-7:05 pm
2 stops8h 40m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$189
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Tue 12/15
3:40 pm-12:36 pm
3 stops43h 56m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$226
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Thu 1/28
8:00 am-9:59 pm
3 stops12h 59m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$230
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Des Moines to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
DSM-RDU
DSM-CLT
DSM-AVL
DSM-ILM
DSM-GSO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to North Carolina
DSM-USNC
DSM-RDU
DSM-CLT
DSM-AVL
DSM-ILM
What is the cheapest month to book a flight from Des Moines to North Carolina?
Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $383). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to NC?
Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 26, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.
How much does it cost to fly round-trip from Des Moines to North Carolina?
Airfare is below average for this route at the moment.
Des Moines to North Carolina flights typically cost between $476 and $553 in November.The cheapest round-trip price found within the last 5 days was $263 on Multiple Airlines (Nov 30-Dec 3).
How far ahead should I book a flight from Des Moines to North Carolina?
The best time to book flights from Des Moines to North Carolina is 12 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated October 26, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
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Alternative routes for Des Moines to North Carolina
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Complete your trip
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Des Moines and North Carolina flights
Browse other Des Moines and North Carolina flight options. Last updated on October 26, 2026.
Popular flight searches
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Des Moines to North Carolina flights
Consider these flights traveling from Des Moines to North Carolina.
Top 4 airlines flying from Des Moines to North Carolina
Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$405 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$426 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$309 | Average$441 | FlexibilityNo cancel fee | On-time63% |