HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
North Carolina

$96+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Jun 23 — Jun 301
Mon 6/23
Mon 6/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to North Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated June 18, 2025.

Round-trip from

$150
(Southwest)

One-way from

$96
(Mytrip)

Popular in

March

Cheapest in

September

Average price

$399

Good round-trip deal

$353 or less

Good one-way deal

$188 or less
From Des Moines to North Carolina
Search Deals
One-way flight from Des Moines to North Carolina
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to North Carolina.
Search Deals
Price to beat on a one-way flight from Des Moines to North Carolina.
Search Deals

Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/68:25 amDSM - CLT
1 stop8h 35mSouthwest
Mon 8/117:50 pmCLT - DSM
1 stop4h 00mSouthwest
Deal found 6/17$150
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/142:00 pmDSM - CLT
2 stops22h 40mMultiple Airlines
Fri 7/189:24 amCLT - DSM
1 stop9h 42mMultiple Airlines
Deal found 6/16$193
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:00 amDSM - RDU
1 stop7h 25mSouthwest
Mon 8/258:05 amRDU - DSM
1 stop4h 00mSouthwest
Deal found 6/17$217
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/55:00 amDSM - ORF
1 stop5h 13mAmerican Airlines
Tue 8/127:51 pmORF - DSM
1 stop4h 59mAmerican Airlines
Deal found 6/18$217
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/125:29 pmDSM - MYR
1 stop4h 42mAmerican Airlines
Tue 8/1910:53 amMYR - DSM
1 stop5h 25mAmerican Airlines
Deal found 6/17$217
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/318:30 amDSM - ORF
1 stop7h 34mAllegiant Air
Thu 8/79:05 amORF - DSM
1 stop24h 44mAllegiant Air
Deal found 6/16$220
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/123:38 pmDSM - ORF
1 stop5h 02mUnited Airlines
Wed 8/206:00 amORF - DSM
2 stops9h 10mUnited Airlines
Deal found 6/17$222
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:34 pmDSM - CLT
Nonstop2h 22mAmerican Airlines
Fri 9/1210:00 pmCLT - DSM
1 stop12h 39mAmerican Airlines
Deal found 6/18$225
This Mytrip deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/186:00 amDSM - MYR
1 stop7h 33mMultiple Airlines
Fri 8/228:45 amMYR - DSM
1 stop7h 05mMultiple Airlines
Deal found 6/17$228
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/318:30 amDSM - ORF
1 stop7h 34mMultiple Airlines
Thu 8/79:05 amORF - DSM
2 stops14h 33mMultiple Airlines
Deal found 6/16$236
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/116:30 pmDSM - MYR
1 stop4h 19mDelta
Wed 8/206:00 amMYR - DSM
1 stop5h 38mDelta
Deal found 6/17$237
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/128:17 amDSM - RDU
1 stop5h 38mAmerican Airlines
Sat 8/239:15 amRDU - DSM
1 stop6h 36mAmerican Airlines
Deal found 6/16$242

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 8/6

8:25 am-4:35 pm

2 stops7h 10m

Charlotte Douglas

Mon 8/11

7:50 pm-10:50 pm

1 stop4h 00m

$150

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 7/14

2:00 pm-1:40 pm

2 stops22h 40m

Charlotte Douglas

Fri 7/18

9:24 am-6:06 pm

1 stop9h 42m

$193

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Tue 8/5

5:00 am-11:13 am

1 stop5h 13m

Norfolk

Tue 8/12

7:51 pm-11:50 pm

1 stop4h 59m

$217

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Thu 8/21

7:00 am-3:25 pm

1 stop7h 25m

Raleigh-Durham

Mon 8/25

8:05 am-11:05 am

1 stop4h 00m

$217

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Tue 8/12

5:29 pm-11:11 pm

1 stop4h 42m

Myrtle Beach Intl

Tue 8/19

7:03 pm-11:50 pm

1 stop5h 47m

$217

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Thu 7/31

8:30 am-5:04 pm

1 stop7h 34m

Norfolk

Thu 8/7

9:05 am-8:49 am

1 stop24h 44m

$220

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Tue 8/12

3:38 pm-9:40 pm

1 stop5h 02m

Norfolk

Wed 8/20

6:00 am-2:10 pm

2 stops9h 10m

$222

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 9/12

5:34 pm-8:56 pm

Nonstop2h 22m

Charlotte Douglas

Fri 9/12

10:00 pm-9:39 am

1 stop12h 39m

$225

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Mon 8/18

6:00 am-2:33 pm

1 stop7h 33m

Myrtle Beach Intl

Fri 8/22

8:45 am-2:50 pm

1 stop7h 05m

$228

Des MoinesNorfolk

DSM - ORF

DSMORF

Des Moines

Thu 7/31

8:30 am-5:04 pm

1 stop7h 34m

Norfolk

Thu 8/7

9:05 am-10:38 pm

2 stops14h 33m

$236

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/18

Showing 1-10 of 57 results
1
2
3
...
6

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Rainfall in North Carolina by month

Plan your trip to North Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in North Carolina ranges from 3.0 - 4.2 inches per month. August is typically the wettest month, when rainfall can reach 4.2 in. April is typically the driest time to visit North Carolina when rainfall is around 3.0 in.

Temperature in North Carolina by month

Plan your trip to North Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated June 18, 2025.
To help decide which airline to fly from Des Moines to North Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,280 reviews
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,964 reviews
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,810 reviews
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.3
Good
722 reviews
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,280 reviews

Overall

8.0

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $109. However, be on the lookout for offers from Frontier and United Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Norfolk or Des Moines - Knoxville McGhee Tyson when deciding on the best route from Des Moines to North Carolina.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Denver flights
Omaha to Dallas/Fort Worth flights
Omaha to Seattle flights
Omaha to Atlanta flights
Cedar Rapids to Denver flights
Omaha to Las Vegas flights
Cedar Rapids to Dallas/Fort Worth flights
Des Moines to Seattle flights
Omaha to LaGuardia flights
Des Moines to O'Hare Intl flights
Omaha to Denver flights
Des Moines to LaGuardia flights
Omaha to Orlando flights
Omaha to O'Hare Intl flights
Omaha to San Francisco flights
Des Moines to John F Kennedy Intl flights
Omaha to Miami flights
Omaha to Love Field flights
Omaha to Nashville flights
Cedar Rapids to Sky Harbor Intl flights
Omaha to Los Angeles flights
Cedar Rapids to Seattle flights
Omaha to John F Kennedy Intl flights
Des Moines to Dallas/Fort Worth flights
Des Moines to Las Vegas flights
Omaha to San Diego flights
Des Moines to Orlando flights
Moline to Dallas/Fort Worth flights
Cedar Rapids to Orlando flights
Des Moines to Hobby flights
Cedar Rapids to Reagan-National flights
Moline to Denver flights
Omaha to Boston flights
Omaha to Hobby flights
Omaha to Newark flights
Des Moines to Dulles Intl flights
Omaha to Dulles Intl flights
Des Moines to Sky Harbor Intl flights
Des Moines to George Bush Intcntl flights
Omaha to Midway flights
Cedar Rapids to LaGuardia flights
Des Moines to Reagan-National flights
Omaha to Sky Harbor Intl flights
Des Moines to Fort Lauderdale flights
Des Moines to Salt Lake City flights
Cedar Rapids to Newark flights
Des Moines to Atlanta flights
Omaha to George Bush Intcntl flights
Des Moines to San Francisco flights
Moline to Orlando flights

Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$233Average$358FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$294Average$391FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$312Average$429FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.