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North Carolina

$90+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
ago. 27 — sep. 31
jue. 8/27
jue. 9/3
1 adult, Economy
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Cheap flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/113:54 pm
DSM
-
MYR
1 stop15h 04m
Multiple Airlines
jue. 10/158:35 am
MYR
-
DSM
1 stop7h 07m
Multiple Airlines
Deal found 7/25$223
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/18:00 am
DSM
-
RDU
2 stops15h 17m
Multiple Airlines
jue. 11/57:05 am
RDU
-
DSM
1 stop26h 16m
Multiple Airlines
Deal found 7/23$243
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/271:58 pm
DSM
-
TYS
1 stop28h 36m
Allegiant Air
mié. 9/304:14 pm
TYS
-
DSM
1 stop17h 48m
Allegiant Air
Deal found 7/27$249
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2411:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
jue. 10/17:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/26$257
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/135:12 pm
DSM
-
TYS
1 stop28h 12m
Multiple Airlines
vie. 8/212:51 pm
TYS
-
DSM
2 stops42h 47m
Multiple Airlines
Deal found 7/27$262
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2411:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
dom. 9/277:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/27$264
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/18:10 am
DSM
-
RDU
1 stop11h 52m
Multiple Airlines
mié. 10/74:20 pm
RDU
-
DSM
2 stops23h 22m
Multiple Airlines
Deal found 7/23$265
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/1311:29 am
DSM
-
CLT
1 stop6h 30m
Frontier
jue. 9/177:54 pm
CLT
-
DSM
1 stop24h 39m
Frontier
Deal found 7/25$265
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/253:04 pm
DSM
-
RDU
1 stop17h 04m
Multiple Airlines
dom. 9/272:54 pm
RDU
-
DSM
1 stop6h 03m
Multiple Airlines
Deal found 7/27$266
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/510:30 am
DSM
-
AVL
1 stop6h 47m
American Airlines
mar. 9/85:34 pm
AVL
-
DSM
1 stop6h 51m
American Airlines
Deal found 7/23$275
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/46:40 am
DSM
-
RDU
2 stops16h 49m
Multiple Airlines
mié. 10/712:05 pm
RDU
-
DSM
1 stop27h 37m
Multiple Airlines
Deal found 7/27$277
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/135:40 am
DSM
-
TYS
1 stop4h 31m
Delta
sáb. 8/227:30 am
TYS
-
DSM
1 stop4h 13m
Delta
Deal found 7/23$279

Find flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated julio 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$223
(Kiwi.com)

One-way from

$90
(Kiwi.com)

Popular in

August

Cheapest in

September

Average price

$406

Good round-trip deal

$389 or less

Good one-way deal

$259 or less
Provider with most accurate pricing for Des Moines-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Raleigh-Durham flights.
Search Deals
From Des Moines to North Carolina
Search Deals
One-way flight from Des Moines to North Carolina
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from Des Moines to North Carolina.
Search Deals
Price to beat on a one-way flight from Des Moines to North Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 28, 2026.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

sáb. 9/5

10:30 am-6:17 pm

1 stop6h 47m

Asheville Regional

mar. 9/8

5:34 pm-11:25 pm

1 stop6h 51m

$275

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

sáb. 8/22

11:32 am-4:58 pm

1 stop4h 26m

Knoxville McGhee Tyson

sáb. 8/29

5:45 am-2:16 pm

2 stops9h 31m

$284

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

mié. 10/21

2:01 pm-9:54 pm

1 stop6h 53m

Asheville Regional

mié. 10/28

7:45 pm-11:58 pm

1 stop5h 13m

$285

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

mar. 8/25

5:40 am-11:11 am

1 stop4h 31m

Knoxville McGhee Tyson

sáb. 8/29

11:38 am-5:18 pm

1 stop6h 40m

$287

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

lun. 9/14

6:54 pm-11:55 pm

1 stop4h 01m

Knoxville McGhee Tyson

lun. 9/21

11:45 am-5:19 pm

1 stop6h 34m

$287

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

sáb. 8/22

7:20 am-5:40 pm

2 stops9h 20m

Knoxville McGhee Tyson

sáb. 8/29

6:50 am-2:10 pm

2 stops8h 20m

$289

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

mié. 10/21

1:24 pm-8:49 pm

1 stop6h 25m

Knoxville McGhee Tyson

mié. 10/28

9:58 am-5:23 pm

2 stops8h 25m

$292

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

mar. 8/25

3:02 pm-9:45 pm

1 stop5h 43m

Knoxville McGhee Tyson

sáb. 8/29

5:45 am-2:16 pm

2 stops9h 31m

$292

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

jue. 9/10

4:14 pm-11:07 pm

1 stop5h 53m

Asheville Regional

lun. 9/14

7:45 pm-11:41 pm

1 stop4h 56m

$302

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

sáb. 8/22

8:10 am-2:52 pm

1 stop5h 42m

Wilmington New Hanover County

sáb. 8/29

7:07 pm-12:35 am

1 stop6h 28m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, September is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $368). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 28, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

How much does it cost to fly round-trip from Des Moines to North Carolina?

Airfare is below average for this route at the moment.
Des Moines to North Carolina flights typically cost between $373 and $581 in September.
The cheapest round-trip price found within the last 5 days was $257 on Frontier (Sep 24-Oct 1).

How far ahead should I book a flight from Des Moines to North Carolina?

The best time to book flights from Des Moines to North Carolina is 40 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated julio 28, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Southwest
8.0
Very good
4,229 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
Delta
7.8
Good
8,487 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
United Airlines
7.4
Good
10,047 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.
American Airlines
7.1
Good
11,847 reviews
Southwest
8.0
Very good
4,229 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How popular is this Des Moines to North Carolina flight route?

    The Des Moines to North Carolina flight path was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Des Moines to North Carolina?

    Departing from Des Moines to North Carolina will take you 4h 26m. Airlines will cover a distance of 654 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $135. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Myrtle Beach Intl or Des Moines - Raleigh-Durham when deciding on the best route from Des Moines to North Carolina.

  • What are the cheapest flights from Des Moines to North Carolina?

    On average you can expect to pay $395 for a flight from Des Moines to North Carolina. The cheapest flight overall is $190 while the most popular route, (Des Moines - Charlotte Douglas) is currently priced at $321.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $368). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $580). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Omaha to Dallas/Fort Worth flights
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Omaha to Atlanta flights
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Omaha to George Bush Intcntl flights
Cedar Rapids to John F Kennedy Intl flights
Omaha to Sky Harbor Intl flights
Cedar Rapids to Newark flights
Omaha to Los Angeles flights
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Omaha to Miami flights
Des Moines to Reagan-National flights
Des Moines to Dulles Intl flights
Des Moines to Atlanta flights
Moline to Dallas/Fort Worth flights
Moline to Denver flights
Omaha to Midway flights
Des Moines to Hobby flights
Des Moines to San Francisco flights
Omaha to Honolulu flights
Omaha to Reagan-National flights
Omaha to Dulles Intl flights
Cedar Rapids to Miami flights
Cedar Rapids to Las Vegas flights
Omaha to Nashville flights
Des Moines to Sky Harbor Intl flights
Des Moines to O'Hare Intl flights

Top 4 airlines flying from Des Moines to North Carolina

Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$380FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$411FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$423FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$309Average$433FlexibilityNo cancel feeOn-time63%

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