$110+ Cheap flights from Des Moines (DSM) to North Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to North Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to North CarolinaExplore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Sat 10/3111:37 am -
1 stop28h 22m
Deal found 9/9![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
2 stops45h 40m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:05 am -
1 stop10h 08m
Fri 10/94:37 pm -
1 stop6h 31m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:45 pm -
1 stop19h 24m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop16h 37m
Wed 9/306:35 am -
2 stops32h 35m
Deal found 9/8![Multiple Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:02 pm -
1 stop5h 53m
Wed 9/306:00 am -
1 stop5h 31m
Deal found 9/8![United Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:45 pm -
1 stop19h 24m
Sat 10/32:54 pm -
1 stop22h 45m
Deal found 9/8![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop6h 12m
Sat 10/32:54 pm -
1 stop22h 45m
Deal found 9/8![Multiple Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:12 pm -
1 stop5h 34m
Sat 10/177:45 pm -
1 stop5h 13m
Deal found 9/9![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:11 pm -
1 stop4h 38m
Sat 10/246:00 am -
1 stop5h 31m
Deal found 9/9![United Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop7h 38m
Wed 10/285:37 pm -
1 stop22h 05m
Deal found 9/7![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
2 stops25h 58m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$290
Best flights from Des Moines to North CarolinaDiscover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:55 am -
1 stop6h 04m
Sat 11/145:45 am -
2 stops7h 35m
Deal found 9/9![United Airlines logo]()
$292
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/131:00 pm -
1 stop5h 34m
Tue 2/165:50 am -
1 stop4h 34m
Deal found 9/8![Delta logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:30 am -
1 stop24h 22m
Fri 12/189:18 am -
1 stop7h 13m
Deal found 9/7![Allegiant Air logo]()
$320
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops12h 45m
Tue 11/101:00 pm -
2 stops10h 00m
Deal found 9/8![Southwest logo]()
$331
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:00 am -
2 stops9h 54m
Wed 9/3011:27 am -
1 stop6h 59m
Deal found 9/9![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:50 pm -
1 stop4h 42m
Tue 10/202:25 pm -
1 stop5h 49m
Deal found 9/9![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:24 pm -
1 stop7h 22m
Thu 10/86:05 am -
1 stop5h 26m
Deal found 9/8![United Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:10 am -
1 stop4h 37m
Tue 11/177:00 am -
1 stop8h 13m
Deal found 9/8![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops11h 45m
Sat 11/148:15 am -
2 stops12h 25m
Deal found 9/9![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:54 pm -
1 stop4h 51m
Tue 10/202:25 pm -
1 stop5h 49m
Deal found 9/9![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/123:25 pm -
1 stop5h 07m
Mon 2/155:15 pm -
1 stop7h 06m
Deal found 9/8![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:50 am -
2 stops12h 50m
Sat 10/246:40 am -
2 stops8h 00m
Deal found 9/9![Southwest logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:28 am -
1 stop4h 52m
Sun 12/135:59 pm -
1 stop7h 27m
Deal found 9/6![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:27 pm -
1 stop7h 47m
Sat 10/1010:42 am -
1 stop4h 33m
Deal found 9/5![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:25 pm -
1 stop4h 10m
Mon 11/97:00 pm -
1 stop5h 00m
Deal found 9/8![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:07 pm -
1 stop7h 21m
Mon 11/97:35 am -
1 stop7h 38m
Deal found 9/9![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:30 pm -
1 stop6h 38m
Wed 10/76:30 am -
1 stop5h 12m
Deal found 9/10![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:26 pm -
1 stop6h 23m
Sat 10/249:00 am -
1 stop8h 20m
Deal found 9/5![United Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:30 am -
1 stop7h 42m
Fri 12/188:00 am -
2 stops28h 49m
Deal found 9/9![Allegiant Air logo]()
$469
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:26 am -
1 stop6h 33m
Thu 11/125:15 am -
1 stop6h 36m
Deal found 9/9![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:55 am -
1 stop7h 50m
Sun 1/108:00 am -
2 stops14h 35m
Deal found 9/6![Southwest logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops9h 23m
Wed 11/1112:02 pm -
2 stops10h 17m
Deal found 9/8![American Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:32 am -
1 stop4h 26m
Tue 9/295:45 am -
2 stops7h 49m
Deal found 9/5![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:35 am -
2 stops7h 30m
Tue 10/202:45 pm -
2 stops8h 15m
Deal found 9/9![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:20 am -
1 stop6h 59m
Fri 12/188:00 am -
1 stop7h 13m
Deal found 9/7![Delta logo]()
$342
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:31 pm -
2 stops7h 24m
Sun 12/65:10 am -
1 stop6h 38m
Deal found 9/9![American Airlines logo]()
$414
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:11 pm -
1 stop4h 48m
Sat 10/246:48 am -
1 stop6h 54m
Deal found 9/9![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:20 pm -
2 stops7h 30m
Sat 10/3112:00 pm -
2 stops6h 45m
Deal found 9/9![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:01 pm -
2 stops7h 01m
Sun 10/258:12 pm -
1 stop4h 46m
Deal found 9/5![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:50 pm -
1 stop4h 51m
Fri 11/64:44 pm -
1 stop6h 49m
Deal found 9/8![Delta logo]()
$348
Last-minute flights from Des Moines to North CarolinaDiscover last-minute flight deals from Des Moines to North Carolina. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to North Carolina. Data last updated September 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
2 stops45h 40m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop16h 37m
Wed 9/306:35 am -
2 stops32h 35m
Deal found 9/8![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop6h 12m
Sat 10/32:54 pm -
1 stop22h 45m
Deal found 9/8![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:05 am -
1 stop10h 08m
Fri 10/94:37 pm -
1 stop6h 31m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
2 stops25h 58m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:02 pm -
1 stop5h 53m
Wed 9/306:00 am -
1 stop5h 31m
Deal found 9/8![United Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:45 pm -
1 stop19h 24m
Thu 10/19:35 pm -
1 stop12h 00m
Deal found 9/8![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:45 pm -
1 stop19h 24m
Sat 10/32:54 pm -
1 stop22h 45m
Deal found 9/8![Multiple Airlines logo]()
$283
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:12 pm -
1 stop5h 34m
Sat 10/177:45 pm -
1 stop5h 13m
Deal found 9/9![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:26 pm -
1 stop6h 23m
Sat 10/246:03 pm -
1 stop4h 20m
Deal found 9/9![United Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
1 stop7h 38m
Wed 10/285:37 pm -
1 stop22h 05m
Deal found 9/7![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:43 am -
1 stop6h 57m
Sat 10/3111:37 am -
1 stop28h 22m
Deal found 9/9![Multiple Airlines logo]()
$187
One-way flights from Des Moines to North CarolinaSearch for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
2 stops38h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:54 pm -
1 stop27h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Allegiant Air logo]()
$130
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:35 pm -
1 stop18h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:30 am -
1 stop14h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Allegiant Air logo]()
$147
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:29 am -
1 stop6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:05 am -
1 stop10h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:43 am -
1 stop11h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
2 stops45h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop22h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:04 pm -
1 stop17h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$163
Find flight deals from Des Moines to North Carolina
Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $187 (Kiwi.com) |
One-way from | $110 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $471 |
Good round-trip deal | $413 or less |
Good one-way deal | $176 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesAsheville
DSM Des Moines - AVL Asheville Regional
DSMAVL
Des Moines
Sun 10/18
3:54 pm-8:09 pm
1 stop27h 15m
Asheville Regional
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
Des MoinesAsheville
DSM Des Moines - AVL Asheville Regional
DSMAVL
Des Moines
Sun 9/27
7:30 am-11:10 pm
1 stop14h 40m
Asheville Regional
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$147
Des MoinesWilmington
DSM Des Moines - ILM Wilmington New Hanover County
DSMILM
Des Moines
Mon 9/28
10:05 am-9:13 pm
1 stop10h 08m
Wilmington New Hanover County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$151
Des MoinesNorfolk
DSM Des Moines - ORF Norfolk
DSMORF
Des Moines
Sun 9/27
1:58 pm-12:29 pm
2 stops45h 31m
Norfolk
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$154
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Fri 10/9
3:04 pm-9:08 am
1 stop17h 04m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$158
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Thu 10/8
6:00 am-12:28 pm
1 stop5h 28m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
Des MoinesRaleigh
DSM Des Moines - RDU Raleigh-Durham
DSMRDU
Des Moines
Tue 10/20
3:00 pm-9:10 pm
1 stop5h 10m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$163
Des MoinesKnoxville
DSM Des Moines - TYS Knoxville McGhee Tyson
DSMTYS
Des Moines
Tue 10/6
5:35 am-1:40 pm
1 stop7h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$172
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Wed 10/7
3:00 pm-9:10 pm
1 stop5h 10m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Des MoinesCharlotte
DSM Des Moines - CLT Charlotte Douglas
DSMCLT
Des Moines
Mon 11/9
5:25 am-3:50 pm
1 stop9h 25m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$184
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
DSM-AVL
DSM-ILM
DSM-RDU
DSM-TYS
DSM-ORF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to North Carolina
DSM-USNC
DSM-AVL
DSM-ILM
DSM-RDU
DSM-TYS
What is the cheapest month to book a flight from Des Moines to North Carolina?
Currently, June is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $381). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to NC?
Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.
How much does it cost to fly round-trip from Des Moines to North Carolina?
Airfare is below average for this route at the moment.
Des Moines to North Carolina flights typically cost between $401 and $471 in October.The cheapest round-trip price found within the last 5 days was $187 on Multiple Airlines (Oct 29-Oct 31).
How far ahead should I book a flight from Des Moines to North Carolina?
The best time to book flights from Des Moines to North Carolina is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated September 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Des Moines to North Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Entertainment
7.5
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
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Alternative routes for Des Moines to North Carolina
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Complete your trip
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Des Moines and North Carolina flights
Browse other Des Moines and North Carolina flight options. Last updated on September 10, 2026.
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Des Moines to North Carolina flights
Consider these flights traveling from Des Moines to North Carolina.
Top 4 airlines flying from Des Moines to North Carolina
Discover the top 4 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$400 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$426 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$269 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$309 | Average$433 | FlexibilityNo cancel fee | On-time63% |