$119+ Cheap flights from Des Moines (DSM) to O'Hare Intl (ORD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to O'Hare Intl with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Chicago O'Hare Intl are usually found in February or December, booked 19 days in advance, depart on a Friday or Thursday and return on a Saturday
Cheap flight deals from Des Moines to O'Hare Intl
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to O'Hare IntlExplore the most affordable flight options available from Des Moines to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Des Moines to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:55 am -
Nonstop1h 39m
Mon 11/94:00 pm -
Nonstop1h 28m
Deal found 9/8![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/169:25 am -
Nonstop1h 45m
Wed 12/1610:53 pm -
Nonstop1h 33m
Deal found 9/9![American Airlines logo]()
$245
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
Nonstop1h 41m
Mon 10/1210:00 pm -
Nonstop1h 35m
Deal found 9/8![United Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:20 pm -
1 stop5h 18m
Wed 10/79:59 am -
1 stop4h 26m
Deal found 9/9![Delta logo]()
$257
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:57 am -
1 stop3h 39m
Fri 10/96:00 am -
1 stop4h 11m
Deal found 9/8![Delta logo]()
$267
This KAYAK deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:48 pm -
1 stop4h 51m
Thu 11/129:59 am -
1 stop4h 09m
Deal found 9/8![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop6h 50m
Wed 10/146:00 am -
2 stops32h 42m
Deal found 9/9![Multiple Airlines logo]()
$287
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
Nonstop1h 36m
Thu 10/159:00 am -
Nonstop1h 31m
Deal found 9/8![United Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:45 pm -
Nonstop1h 40m
Thu 11/128:50 am -
Nonstop1h 42m
Deal found 9/8![United Airlines logo]()
$296
This KAYAK deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:46 pm -
1 stop5h 41m
Thu 10/226:20 am -
1 stop3h 51m
Deal found 9/8![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:27 am -
Nonstop1h 39m
Sun 10/1811:00 am -
Nonstop1h 32m
Deal found 9/8![United Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
Nonstop1h 41m
Fri 10/1611:00 am -
Nonstop1h 34m
Deal found 9/8![United Airlines logo]()
$300
Best flights from Des Moines to O'Hare IntlDiscover carefully curated flight deals from Des Moines to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Des Moines to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:46 pm -
1 stop3h 52m
Fri 10/236:20 am -
1 stop3h 51m
Deal found 9/9![Delta logo]()
$318
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:00 am -
Nonstop1h 36m
Sun 9/2712:50 pm -
Nonstop1h 25m
Deal found 9/9![United Airlines logo]()
$447
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:00 am -
1 stop3h 55m
Wed 2/246:00 am -
1 stop4h 20m
Deal found 9/9![Delta logo]()
$318
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:46 pm -
1 stop3h 52m
Fri 10/166:20 am -
1 stop3h 51m
Deal found 9/8![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:01 pm -
1 stop5h 26m
Fri 11/66:20 am -
1 stop3h 51m
Deal found 9/9![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:12 pm -
1 stop16h 28m
Sun 11/299:25 pm -
Nonstop1h 34m
Deal found 9/8![United Airlines logo]()
$571
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2012:31 pm -
1 stop6h 04m
Tue 1/125:20 pm -
1 stop4h 04m
Deal found 9/5![Delta logo]()
$569
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:59 pm -
1 stop3h 34m
Thu 9/246:10 am -
1 stop4h 07m
Deal found 9/8![Delta logo]()
$572
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:46 pm -
1 stop5h 41m
Thu 10/1511:19 am -
2 stops7h 52m
Deal found 9/7![Delta logo]()
$574
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:40 am -
2 stops6h 06m
Tue 2/166:00 am -
1 stop4h 20m
Deal found 9/6![Delta logo]()
$604
Last-minute flights from Des Moines to O'Hare IntlDiscover last-minute flight deals from Des Moines to O'Hare Intl. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to O'Hare Intl. Data last updated September 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:57 pm -
Nonstop2h 03m
Wed 10/75:16 pm -
Nonstop1h 40m
Deal found 9/9![American Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:20 pm -
1 stop5h 18m
Wed 10/79:59 am -
1 stop4h 26m
Deal found 9/9![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop6h 50m
Wed 10/146:00 am -
2 stops32h 42m
Deal found 9/9![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:57 am -
1 stop3h 39m
Fri 10/96:00 am -
1 stop4h 11m
Deal found 9/8![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
Nonstop1h 41m
Mon 10/1210:00 pm -
Nonstop1h 35m
Deal found 9/8![United Airlines logo]()
$247
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:55 pm -
Nonstop1h 38m
Sun 10/118:59 am -
Nonstop1h 31m
Deal found 9/8![United Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am -
Nonstop1h 36m
Thu 10/159:00 am -
Nonstop1h 31m
Deal found 9/8![United Airlines logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
Nonstop1h 41m
Fri 10/1611:00 am -
Nonstop1h 34m
Deal found 9/8![United Airlines logo]()
$300
This KAYAK deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:57 am -
1 stop5h 43m
Fri 10/163:30 pm -
1 stop5h 30m
Deal found 9/8![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:27 am -
Nonstop1h 39m
Sun 10/1811:00 am -
Nonstop1h 32m
Deal found 9/8![United Airlines logo]()
$298
This KAYAK deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:46 pm -
1 stop5h 41m
Thu 10/226:20 am -
1 stop3h 51m
Deal found 9/8![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 am -
Nonstop1h 40m
Mon 11/28:25 pm -
Nonstop1h 30m
Deal found 9/9![United Airlines logo]()
$306
One-way flights from Des Moines to O'Hare IntlSearch for one-way flight options from Des Moines to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Des Moines to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:27 am -
Nonstop1h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$119
This Trip.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:30 pm -
1 stop27h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$120
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:57 pm -
Nonstop2h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$129
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:59 pm -
1 stop3h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$139
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:45 pm -
Nonstop1h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$148
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:26 pm -
Nonstop1h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![American Airlines logo]()
$154
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:00 am -
Nonstop1h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$155
This Trip.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:29 am -
1 stop12h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:29 am -
1 stop12h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Frontier logo]()
$161
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
Nonstop1h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:30 pm -
1 stop27h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$169
Find flight deals from Des Moines to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (American Airlines) |
One-way from | $119 (United Airlines) |
Popular in | April |
Cheapest in | February |
Average price | $355 |
Good round-trip deal | $426 or less |
Good one-way deal | $244 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Des Moines to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Tue 11/10
11:00 am-2:55 pm
1 stop3h 55m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Wed 11/4
4:01 pm-9:27 pm
1 stop5h 26m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Sat 11/7
10:57 am-4:41 pm
1 stop5h 44m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Fri 12/4
4:53 pm-9:35 pm
1 stop4h 42m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$139
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Fri 10/2
5:59 pm-9:33 pm
1 stop3h 34m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$139
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Wed 11/11
8:00 am-9:40 am
Nonstop1h 40m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$154
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Thu 12/10
9:30 am-11:12 am
Nonstop1h 42m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$154
Quickest round-trip
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Thu 10/8
1:24 pm-3:00 pm
Nonstop1h 36m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Fri 10/2
8:00 am-9:36 am
Nonstop1h 36m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Wed 10/21
1:24 pm-3:00 pm
Nonstop1h 36m
Chicago O'Hare Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Des Moines to O'Hare Intl
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to O'Hare Intl in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Des Moines with our price prediction graph.
DSM-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Chicago O'Hare Intl Airport
Prices
Airlines
How far ahead should I book a flight from Des Moines to Chicago O'Hare Intl Airport?
To ensure you get the cheapest price possible for a flight from Des Moines to Chicago O'Hare Intl Airport, you should look to book at least 18 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Des Moines to Chicago O'Hare Intl Airport?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Chicago O'Hare Intl Airport (average of $224). Flying from Des Moines to Chicago O'Hare Intl Airport in April is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to ORD?
Find hourly flight availability from Des Moines to O'Hare Intl. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 52% on flights from Des Moines to Chicago O'Hare Intl Airport by exploring options for tickets in the morning.
What is the cheapest day to fly from Des Moines to Chicago O'Hare Intl Airport?
Use this chart to determine the cheapest time to fly round-trip from Des Moines to O'Hare Intl. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Des Moines to Chicago O'Hare Intl Airport flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Des Moines to Chicago O'Hare Intl Airport flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Des Moines to Chicago O'Hare Intl Airport trip
Our travel experts
Reviews of airlines servicing O'Hare Intl
Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Des Moines to Chicago O'Hare Intl Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Boarding
7.7
Crew
8.1
Overall
7.4
Food
6.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locationsBenton Harbor
Rosemont
Lake Geneva
Naperville
Des Plaines
Glenview
Schaumburg
Oakbrook Terrace
Delavan
Oak Brook
Libertyville
Orland Park
Hoffman Estates
Aurora
Beloit
Rockford
South Holland
Elgin
Racine
Janesville
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Top 2 airlines flying from Des Moines to O'Hare Intl
Discover the top 2 airlines that operate flights from Des Moines to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$288 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$332 | FlexibilityNo cancel fee | On-time69% |