$114+ Cheap flights from O'Hare Intl (ORD) to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — DSM
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from O'Hare Intl to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to Des Moines
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Cheapest flights from O'Hare Intl to Des MoinesExplore the most affordable flight options available from O'Hare Intl to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from O'Hare Intl to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:50 am -
Nonstop1h 42m
Sat 11/711:23 am -
Nonstop1h 38m
Deal found 8/27![United Airlines logo]()
$237
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:50 pm -
Nonstop1h 25m
Mon 10/121:24 pm -
Nonstop1h 36m
Deal found 9/1![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:25 am -
1 stop5h 41m
Wed 9/3010:59 am -
1 stop6h 00m
Deal found 8/27![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:00 am -
Nonstop1h 31m
Fri 10/211:27 am -
Nonstop1h 39m
Deal found 8/27![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 11m
Mon 10/123:46 pm -
1 stop5h 41m
Deal found 9/1![Delta logo]()
$269
This KAYAK deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:42 pm -
1 stop3h 31m
Tue 11/176:45 am -
1 stop5h 03m
Deal found 9/1![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 am -
1 stop12h 32m
Mon 9/288:30 pm -
1 stop27h 53m
Deal found 8/30![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop6h 45m
Thu 10/158:43 am -
1 stop13h 56m
Deal found 8/27![Multiple Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:00 pm -
Nonstop1h 28m
Thu 9/246:00 am -
Nonstop1h 41m
Deal found 9/1![United Airlines logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:50 pm -
Nonstop1h 25m
Tue 10/66:55 pm -
Nonstop1h 38m
Deal found 8/27![United Airlines logo]()
$298
This deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:05 am -
Nonstop1h 26m
Thu 9/248:00 am -
Nonstop1h 36m
Deal found 9/1![United Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:30 pm -
Nonstop1h 34m
Sun 10/42:44 pm -
Nonstop1h 46m
Deal found 8/27![American Airlines logo]()
$310
Best flights from O'Hare Intl to Des MoinesDiscover carefully curated flight deals from O'Hare Intl to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from O'Hare Intl to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:00 pm -
Nonstop1h 35m
Thu 10/81:24 pm -
Nonstop1h 36m
Deal found 9/1![United Airlines logo]()
$237
This KAYAK deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:42 pm -
1 stop3h 31m
Tue 11/176:45 am -
1 stop5h 03m
Deal found 9/1![Delta logo]()
$277
This KAYAK deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/49:00 am -
1 stop8h 47m
Thu 1/77:33 pm -
Nonstop1h 47m
Deal found 9/1![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:00 pm -
Nonstop1h 28m
Thu 9/246:00 am -
Nonstop1h 41m
Deal found 9/1![United Airlines logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:50 pm -
Nonstop1h 25m
Tue 10/66:55 pm -
Nonstop1h 38m
Deal found 8/27![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:20 am -
1 stop3h 51m
Wed 10/283:46 pm -
1 stop5h 41m
Deal found 8/28![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am -
Nonstop1h 31m
Wed 10/146:55 pm -
Nonstop1h 38m
Deal found 8/28![United Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:10 am -
1 stop4h 07m
Tue 10/63:46 pm -
1 stop5h 41m
Deal found 8/27![Delta logo]()
$369
This KAYAK deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:29 am -
1 stop5h 35m
Thu 9/2410:35 am -
Nonstop1h 44m
Deal found 8/28![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:00 am -
1 stop4h 11m
Mon 10/193:46 pm -
1 stop5h 41m
Deal found 8/30![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:45 pm -
Nonstop1h 38m
Thu 1/79:37 am -
Nonstop1h 45m
Deal found 9/1![United Airlines logo]()
$355
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1412:54 pm -
Nonstop1h 26m
Thu 9/176:24 am -
Nonstop1h 36m
Deal found 8/31![United Airlines logo]()
$488
Last-minute flights from O'Hare Intl to Des MoinesDiscover last-minute flight deals from O'Hare Intl to Des Moines. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Des Moines. Data last updated September 1, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:00 pm -
Nonstop1h 28m
Thu 9/246:00 am -
Nonstop1h 41m
Deal found 9/1![United Airlines logo]()
$296
This deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:05 am -
Nonstop1h 26m
Thu 9/248:00 am -
Nonstop1h 36m
Deal found 9/1![United Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 am -
1 stop12h 32m
Mon 9/288:30 pm -
1 stop27h 53m
Deal found 8/30![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:00 am -
Nonstop1h 31m
Fri 10/211:27 am -
Nonstop1h 39m
Deal found 8/27![United Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:27 pm -
Nonstop1h 32m
Wed 9/307:58 pm -
Nonstop1h 49m
Deal found 8/27![American Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:25 am -
1 stop5h 41m
Wed 9/3010:59 am -
1 stop6h 00m
Deal found 8/27![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop6h 45m
Thu 10/158:43 am -
1 stop13h 56m
Deal found 8/27![Multiple Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:30 pm -
Nonstop1h 34m
Sun 10/42:44 pm -
Nonstop1h 46m
Deal found 8/27![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/412:50 pm -
Nonstop1h 25m
Tue 10/66:55 pm -
Nonstop1h 38m
Deal found 8/27![United Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:50 pm -
Nonstop1h 25m
Mon 10/121:24 pm -
Nonstop1h 36m
Deal found 9/1![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 11m
Mon 10/123:46 pm -
1 stop5h 41m
Deal found 9/1![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:00 am -
Nonstop1h 34m
Mon 10/126:55 pm -
Nonstop1h 38m
Deal found 8/28![United Airlines logo]()
$311
One-way flights from O'Hare Intl to Des MoinesSearch for one-way flight options from O'Hare Intl to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from O'Hare Intl to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Super.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:30 am -
1 stop28h 14m
Deal found 8/27![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:11 am -
1 stop25h 51m
Deal found 8/28![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:25 am -
1 stop12h 32m
Deal found 8/28![Multiple Airlines logo]()
$120
This CheapOair deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:30 am -
1 stop13h 00m
Deal found 8/30![Frontier logo]()
$127
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:10 am -
1 stop4h 07m
Deal found 9/1![Delta logo]()
$129
This KAYAK deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:25 am -
1 stop5h 41m
Deal found 9/1![Delta logo]()
$139
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:23 am -
1 stop3h 56m
Deal found 8/28![Delta logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:25 am -
1 stop6h 45m
Deal found 8/29![Multiple Airlines logo]()
$144
Find flight deals from O'Hare Intl to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (United Airlines) |
One-way from | $114 (Super.com) |
Popular in | May |
Cheapest in | November |
Average price | $273 |
Good round-trip deal | $372 or less |
Good one-way deal | $235 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Tue 10/6
10:00 pm-11:35 pm
Nonstop1h 35m
Des Moines
Thu 10/8
1:24 pm-3:00 pm
Nonstop1h 36m
$237
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Mon 11/16
5:42 pm-9:13 pm
1 stop3h 31m
Des Moines
Tue 11/17
6:45 am-11:48 am
1 stop5h 03m
$277
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Tue 9/22
4:00 pm-5:28 pm
Nonstop1h 28m
Des Moines
Thu 9/24
6:00 am-7:41 am
Nonstop1h 41m
$296
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Sun 10/4
12:50 pm-2:15 pm
Nonstop1h 25m
Des Moines
Tue 10/6
6:55 pm-8:33 pm
Nonstop1h 38m
$298
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Thu 10/1
9:00 am-10:31 am
Nonstop1h 31m
Des Moines
Wed 10/14
6:55 pm-8:33 pm
Nonstop1h 38m
$311
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Sun 10/25
6:20 am-10:11 am
1 stop3h 51m
Des Moines
Wed 10/28
3:46 pm-9:27 pm
1 stop5h 41m
$355
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Mon 1/4
7:45 pm-9:23 pm
Nonstop1h 38m
Des Moines
Thu 1/7
9:37 am-11:22 am
Nonstop1h 45m
$355
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Sun 10/4
6:10 am-10:17 am
1 stop4h 07m
Des Moines
Tue 10/6
3:46 pm-9:27 pm
1 stop5h 41m
$369
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Mon 10/12
6:00 am-10:11 am
1 stop4h 11m
Des Moines
Mon 10/19
3:46 pm-9:27 pm
1 stop5h 41m
$379
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Mon 1/4
9:00 am-5:47 pm
1 stop8h 47m
Des Moines
Thu 1/7
7:33 pm-9:20 pm
Nonstop1h 47m
$420
Showing 1-10 of 24 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Des Moines in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from O'Hare Intl with our price prediction graph.
ORD-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Des Moines
Prices
Airlines
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Des Moines?
Currently, November is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Des Moines (average of $264). Flying from Chicago O'Hare Intl Airport to Des Moines in May is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to DSM?
Find hourly flight availability from O'Hare Intl to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 1, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 52% on flights from Chicago O'Hare Intl Airport to Des Moines by exploring options for tickets at noon.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Des Moines. Price data was last updated on August 29, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Des Moines flight should consider departing on Thursday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 1, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Chicago O'Hare Intl Airport to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Boarding
7.7
Entertainment
7.1
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Boarding
7.7
Entertainment
7.1
Food
6.7
Overall
7.4
Crew
8.1
Comfort
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Top 2 airlines flying from O'Hare Intl to Des Moines
Discover the top 2 airlines that operate flights from O'Hare Intl to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$432 | FlexibilityNo cancel fee | On-time69% |