$103+ Cheap flights from Des Moines (DSM) to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IllinoisExplore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- STL
2 stops39h 49m
Multiple Airlines
Thu 8/67:10 pm
STL
- DSM
1 stop25h 21m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Sat 8/810:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/11![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DSM
- MDW
1 stop6h 39m
Delta
Sat 8/89:59 am
MDW
- DSM
1 stop4h 05m
Delta
Deal found 6/11![Delta logo]()
$252
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 7/2210:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/15![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Wed 7/298:42 am
ORD
- DSM
Nonstop1h 35m
United Airlines
Deal found 6/16![United Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 am
DSM
- ORD
Nonstop1h 36m
American Airlines
Wed 7/1510:31 pm
ORD
- DSM
Nonstop1h 30m
American Airlines
Deal found 6/15![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 8/108:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/11![Southwest logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Thu 7/237:10 pm
STL
- DSM
1 stop26h 01m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$260
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/148:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/12![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:40 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Thu 8/68:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/16![Southwest logo]()
$263
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:50 pm
DSM
- ORD
Nonstop1h 40m
American Airlines
Thu 8/65:46 pm
ORD
- DSM
Nonstop1h 33m
American Airlines
Deal found 6/16![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:07 pm
DSM
- ORD
Nonstop1h 43m
American Airlines
Wed 10/286:40 am
ORD
- DSM
Nonstop1h 27m
American Airlines
Deal found 6/16![American Airlines logo]()
$264
Best flights from Des Moines to IllinoisDiscover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 7/159:20 pm
MDW
- DSM
Nonstop1h 30m
Southwest
Deal found 6/13![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:00 am
DSM
- ORD
Nonstop1h 36m
United Airlines
Wed 8/269:00 am
ORD
- DSM
Nonstop1h 26m
United Airlines
Deal found 6/12![United Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Sun 7/1211:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:30 pm
DSM
- STL
2 stops19h 51m
Multiple Airlines
Thu 7/237:10 pm
STL
- DSM
1 stop26h 01m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
DSM
- MDW
1 stop6h 39m
Delta
Sat 8/89:59 am
MDW
- DSM
1 stop4h 05m
Delta
Deal found 6/14![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 8/108:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/11![Southwest logo]()
$255
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:23 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Thu 7/2312:59 pm
ORD
- DSM
Nonstop1h 28m
United Airlines
Deal found 6/15![United Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- ORD
1 stop4h 42m
Delta
Mon 8/316:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 6/16![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:30 am
DSM
- RFD
1 stop27h 38m
Allegiant Air
Sun 8/211:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$300
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:45 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Fri 7/1010:05 pm
MDW
- DSM
Nonstop1h 30m
Southwest
Deal found 6/14![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
DSM
- ORD
1 stop7h 08m
Delta
Mon 8/106:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 6/11![Delta logo]()
$312
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:29 am
DSM
- STL
1 stop5h 34m
United Airlines
Sun 9/138:50 am
STL
- DSM
1 stop5h 30m
United Airlines
Deal found 6/14![United Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:24 am
DSM
- RFD
1 stop7h 49m
Allegiant Air
Thu 11/121:08 pm
RFD
- DSM
1 stop25h 28m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am
DSM
- STL
1 stop4h 12m
United Airlines
Mon 9/78:50 am
STL
- DSM
1 stop5h 26m
United Airlines
Deal found 6/14![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Fri 8/288:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/11![Southwest logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- RFD
1 stop16h 59m
Allegiant Air
Fri 7/107:50 pm
RFD
- DSM
1 stop20h 19m
Allegiant Air
Deal found 6/14![Allegiant Air logo]()
$330
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/232:45 pm
DSM
- ORD
1 stop4h 45m
Delta
Fri 8/286:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 6/11![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Thu 8/610:05 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/15![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:24 pm
DSM
- ORD
Nonstop1h 39m
United Airlines
Sat 7/188:42 am
ORD
- DSM
Nonstop1h 35m
United Airlines
Deal found 6/15![United Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:48 am
DSM
- RFD
2 stops22h 59m
Multiple Airlines
Sun 8/1610:32 am
RFD
- DSM
1 stop7h 05m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- RFD
1 stop16h 59m
Allegiant Air
Thu 7/911:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/16![Allegiant Air logo]()
$336
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:56 pm
DSM
- ORD
1 stop3h 51m
Delta
Wed 8/198:28 am
ORD
- DSM
1 stop5h 36m
Delta
Deal found 6/15![Delta logo]()
$346
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:40 am
DSM
- STL
2 stops12h 15m
Southwest
Mon 9/76:05 am
STL
- DSM
1 stop5h 20m
Southwest
Deal found 6/14![Southwest logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:24 am
DSM
- RFD
1 stop7h 49m
Multiple Airlines
Thu 11/129:30 am
RFD
- DSM
2 stops22h 24m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$446
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:13 am
DSM
- STL
1 stop7h 21m
United Airlines
Wed 9/26:00 am
STL
- DSM
1 stop4h 26m
United Airlines
Deal found 6/15![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:40 pm
DSM
- STL
2 stops6h 10m
Southwest
Tue 7/145:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Deal found 6/12![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:00 am
DSM
- STL
1 stop4h 11m
United Airlines
Sun 7/195:59 pm
STL
- DSM
1 stop4h 57m
United Airlines
Deal found 6/12![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:54 am
DSM
- ORD
1 stop4h 11m
Delta
Wed 8/512:29 pm
ORD
- DSM
1 stop4h 21m
Delta
Deal found 6/13![Delta logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 am
DSM
- RFD
1 stop11h 59m
Allegiant Air
Fri 7/177:50 pm
RFD
- DSM
1 stop20h 19m
Allegiant Air
Deal found 6/12![Allegiant Air logo]()
$390
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:35 pm
DSM
- MDW
Nonstop1h 25m
Southwest
Sun 8/210:25 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 6/15![Southwest logo]()
$329
Last-minute flights from Des Moines to IllinoisDiscover last-minute flight deals from Des Moines to Illinois. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Illinois. Data last updated June 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:02 am
DSM
- STL
1 stop3h 55m
American Airlines
Tue 7/76:55 am
STL
- DSM
1 stop6h 10m
American Airlines
Deal found 6/15![American Airlines logo]()
$283
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/148:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/12![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Sun 7/1211:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/13![Allegiant Air logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:57 pm
DSM
- ORD
1 stop26h 56m
Multiple Airlines
Sat 7/188:52 pm
ORD
- DSM
1 stop25h 55m
Multiple Airlines
Deal found 6/12![Multiple Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:52 pm
DSM
- ORD
1 stop4h 00m
Delta
Tue 7/216:30 am
ORD
- DSM
1 stop3h 43m
Delta
Deal found 6/12![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 7/2210:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/15![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:50 pm
DSM
- ORD
Nonstop1h 40m
United Airlines
Wed 7/228:42 am
ORD
- DSM
Nonstop1h 35m
United Airlines
Deal found 6/15![United Airlines logo]()
$253
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:00 am
DSM
- ORD
Nonstop1h 36m
American Airlines
Wed 7/1510:31 pm
ORD
- DSM
Nonstop1h 30m
American Airlines
Deal found 6/15![American Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:45 pm
DSM
- MDW
1 stop3h 33m
Delta
Wed 7/229:54 am
MDW
- DSM
1 stop4h 11m
Delta
Deal found 6/15![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:45 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Thu 7/1610:05 pm
MDW
- DSM
Nonstop1h 30m
Southwest
Deal found 6/16![Southwest logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Thu 7/237:10 pm
STL
- DSM
1 stop26h 01m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:08 pm
DSM
- STL
2 stops39h 49m
Multiple Airlines
Thu 8/67:10 pm
STL
- DSM
1 stop25h 21m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$227
One-way flights from Des Moines to IllinoisSearch for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:19 pm
DSM
- ORD
1 stop6h 33m
Frontier
Deal found 6/11![Frontier logo]()
$103
This Frontier deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:19 pm
DSM
- ORD
1 stop6h 33m
Frontier
Deal found 6/16![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:40 pm
DSM
- ORD
1 stop19h 35m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:01 pm
DSM
- STL
1 stop20h 04m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:07 pm
DSM
- ORD
1 stop18h 08m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$114
This Orbitz deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:19 pm
DSM
- ORD
1 stop6h 33m
Frontier
Deal found 6/15![Frontier logo]()
$115
This Expedia deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Deal found 6/12![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/93:41 pm
DSM
- ORD
1 stop28h 12m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:40 pm
DSM
- ORD
1 stop19h 35m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$125
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 6/15![Southwest logo]()
$127
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:53 am
DSM
- ORD
Nonstop1h 45m
American Airlines
Deal found 6/12![American Airlines logo]()
$127
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:33 pm
DSM
- ORD
Nonstop1h 55m
American Airlines
Deal found 6/13![American Airlines logo]()
$128
Find flight deals from Des Moines to Illinois
Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated June 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Kiwi.com) |
One-way from | $103 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $309 |
Good round-trip deal | $378 or less |
Good one-way deal | $213 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Wed 7/15
5:20 am-6:40 am
Nonstop1h 20m
Chicago Midway
Wed 7/15
9:20 pm-10:50 pm
Nonstop1h 30m
$253
Quickest round-trip
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Thu 8/6
5:40 am-7:00 am
Nonstop1h 20m
Chicago Midway
Mon 8/10
8:50 pm-10:10 pm
Nonstop1h 20m
$255
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Thu 8/13
6:00 am-7:36 am
Nonstop1h 36m
Chicago O'Hare Intl
Wed 8/26
9:00 am-10:26 am
Nonstop1h 26m
$263
Des MoinesChicago
DSM - RFD
DSMRFD
Des Moines
Wed 7/8
10:59 am-8:29 am
1 stop21h 30m
Chicago Greater Rockford
Sun 7/12
11:27 am-3:50 pm
1 stop28h 23m
$274
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 7/20
5:30 pm-1:21 pm
2 stops19h 51m
Lambert-St Louis
Thu 7/23
7:10 pm-9:11 pm
1 stop26h 01m
$284
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Wed 7/22
11:23 am-1:03 pm
Nonstop1h 40m
Chicago O'Hare Intl
Thu 7/23
12:59 pm-2:27 pm
Nonstop1h 28m
$291
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Thu 8/6
6:00 am-12:39 pm
1 stop6h 39m
Chicago Midway
Sat 8/8
9:59 am-2:04 pm
1 stop4h 05m
$293
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Sat 8/29
6:00 am-10:42 am
1 stop4h 42m
Chicago O'Hare Intl
Mon 8/31
6:00 am-10:18 am
1 stop4h 18m
$293
Des MoinesChicago
DSM - RFD
DSMRFD
Des Moines
Fri 7/31
8:30 am-12:08 pm
1 stop27h 38m
Chicago Greater Rockford
Sun 8/2
11:27 am-3:50 pm
1 stop28h 23m
$300
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Tue 7/7
3:45 pm-5:05 pm
Nonstop1h 20m
Chicago Midway
Fri 7/10
10:05 pm-11:35 pm
Nonstop1h 30m
$305
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
DSM-MDW
DSM-ORD
DSM-RFD
DSM-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Illinois
DSM-USIL
DSM-MDW
DSM-ORD
DSM-RFD
DSM-STL
What is the cheapest month to book a flight from Des Moines to Illinois?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $126). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IL?
Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 16, 2026.
One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 41% on airfare.
Weekly flight availability from Des Moines to Illinois
Explore weekly flight availability from Des Moines to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 16, 2026.
The most flights from DSM to USIL are scheduled on a Monday (46 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (20 on average).
How much does it cost to fly round-trip from Des Moines to Illinois?
How far ahead should I book a flight from Des Moines to Illinois?
The best time to book flights from Des Moines to Illinois is 18 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Des Moines to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Des Moines to Illinois. Price data was last updated on June 13, 2026.
Travelers seeking maximum savings on their Des Moines to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated June 16, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Illinois
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Complete your trip
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Des Moines and Illinois flights
Browse other Des Moines and Illinois flight options. Last updated on June 16, 2026.
Popular flight searches
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Des Moines to Illinois flights
Consider these flights traveling from Des Moines to Illinois.
Top 2 airlines flying from Des Moines to Illinois
Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$249 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$288 | FlexibilityNo cancel fee | On-time69% |