$101+ Cheap flights from Des Moines (DSM) to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IllinoisExplore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
DSM
- ORD
1 stop17h 31m
Multiple Airlines
Thu 9/107:25 am
ORD
- DSM
1 stop12h 32m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$207
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:22 pm
DSM
- STL
1 stop6h 38m
United Airlines
Tue 9/158:00 am
STL
- DSM
1 stop6h 20m
United Airlines
Deal found 7/27![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Tue 9/153:05 pm
STL
- DSM
2 stops6h 55m
Southwest
Deal found 7/27![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
DSM
- STL
1 stop3h 35m
Southwest
Sat 9/198:30 am
STL
- DSM
2 stops11h 00m
Southwest
Deal found 7/24![Southwest logo]()
$220
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
DSM
- STL
2 stops7h 05m
Southwest
Sat 8/298:30 am
STL
- DSM
2 stops10h 55m
Southwest
Deal found 7/25![Southwest logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
- ORD
1 stop23h 32m
Multiple Airlines
Thu 9/177:25 am
ORD
- DSM
1 stop12h 32m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$226
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
DSM
- STL
1 stop3h 35m
Southwest
Thu 9/176:05 am
STL
- DSM
1 stop5h 20m
Southwest
Deal found 7/27![Southwest logo]()
$232
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 8/248:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/28![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- ORD
Nonstop1h 36m
United Airlines
Sat 8/297:55 pm
ORD
- DSM
Nonstop1h 28m
United Airlines
Deal found 7/27![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:58 pm
DSM
- ORD
Nonstop1h 49m
American Airlines
Thu 9/173:50 pm
ORD
- DSM
Nonstop1h 36m
American Airlines
Deal found 7/27![American Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:55 am
DSM
- ORD
Nonstop1h 50m
American Airlines
Tue 9/156:59 am
ORD
- DSM
Nonstop1h 40m
American Airlines
Deal found 7/24![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:19 pm
DSM
- ORD
1 stop23h 17m
Multiple Airlines
Thu 8/276:00 am
ORD
- DSM
1 stop13h 54m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$241
Best flights from Des Moines to IllinoisDiscover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
DSM
- STL
1 stop3h 35m
Southwest
Sat 9/198:25 am
STL
- DSM
1 stop3h 05m
Southwest
Deal found 7/24![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:22 pm
DSM
- STL
1 stop6h 38m
United Airlines
Tue 9/158:00 am
STL
- DSM
1 stop6h 20m
United Airlines
Deal found 7/27![United Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:00 am
DSM
- STL
1 stop3h 23m
Delta
Thu 9/176:15 am
STL
- DSM
1 stop4h 02m
Delta
Deal found 7/28![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm
DSM
- STL
2 stops23h 12m
Multiple Airlines
Thu 10/112:17 pm
STL
- DSM
1 stop22h 40m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:00 am
DSM
- RFD
1 stop12h 08m
Allegiant Air
Sun 10/1110:30 am
RFD
- DSM
1 stop12h 40m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$338
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Tue 9/153:05 pm
STL
- DSM
2 stops6h 55m
Southwest
Deal found 7/27![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- STL
1 stop3h 25m
Southwest
Tue 9/12:50 pm
STL
- DSM
2 stops6h 10m
Southwest
Deal found 7/28![Southwest logo]()
$214
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:55 pm
DSM
- ORD
Nonstop1h 38m
United Airlines
Sat 10/1711:00 am
ORD
- DSM
Nonstop1h 32m
United Airlines
Deal found 7/24![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- ORD
1 stop4h 42m
Delta
Mon 8/311:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Deal found 7/27![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
DSM
- STL
1 stop3h 35m
Southwest
Thu 9/176:05 am
STL
- DSM
1 stop5h 20m
Southwest
Deal found 7/27![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
DSM
- ORD
1 stop4h 37m
Delta
Wed 9/166:10 am
ORD
- DSM
1 stop4h 07m
Delta
Deal found 7/26![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Thu 9/178:50 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 7/27![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 9/168:35 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 7/26![Southwest logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:18 pm
DSM
- RFD
2 stops21h 09m
Allegiant Air
Sun 10/1810:30 am
RFD
- DSM
1 stop12h 40m
Allegiant Air
Deal found 7/24![Allegiant Air logo]()
$347
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:56 pm
DSM
- ORD
1 stop3h 51m
Delta
Sat 8/296:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 7/27![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:23 am
DSM
- ORD
1 stop5h 54m
Delta
Fri 8/286:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 7/26![Delta logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:26 pm
DSM
- RFD
2 stops22h 21m
Multiple Airlines
Sun 8/309:35 pm
RFD
- DSM
1 stop22h 29m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:28 am
DSM
- RFD
1 stop5h 41m
Allegiant Air
Mon 8/241:13 pm
RFD
- DSM
1 stop9h 00m
Allegiant Air
Deal found 7/26![Allegiant Air logo]()
$361
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Mon 8/318:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/24![Southwest logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:59 am
DSM
- RFD
1 stop10h 07m
Allegiant Air
Sun 10/1810:30 am
RFD
- DSM
1 stop12h 40m
Allegiant Air
Deal found 7/24![Allegiant Air logo]()
$373
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:25 pm
DSM
- MDW
1 stop7h 35m
Southwest
Mon 8/2412:15 pm
MDW
- DSM
1 stop9h 00m
Southwest
Deal found 7/28![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:21 pm
DSM
- ORD
Nonstop1h 39m
United Airlines
Mon 8/315:00 am
ORD
- DSM
1 stop15h 26m
United Airlines
Deal found 7/24![United Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:15 am
DSM
- RFD
1 stop11h 56m
Allegiant Air
Sun 9/279:29 pm
RFD
- DSM
1 stop23h 12m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$384
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:20 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Sat 10/176:15 am
MDW
- DSM
1 stop7h 25m
Southwest
Deal found 7/24![Southwest logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:29 am
DSM
- RFD
1 stop5h 34m
Allegiant Air
Sun 9/279:29 pm
RFD
- DSM
1 stop23h 12m
Allegiant Air
Deal found 7/26![Allegiant Air logo]()
$405
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:40 am
DSM
- STL
2 stops9h 40m
Southwest
Fri 9/183:45 pm
STL
- DSM
2 stops6h 30m
Southwest
Deal found 7/28![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
DSM
- ORD
1 stop6h 59m
Delta
Sun 10/46:10 am
ORD
- DSM
1 stop4h 07m
Delta
Deal found 7/27![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:55 am
DSM
- ORD
2 stops6h 55m
Delta
Mon 8/101:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Deal found 7/26![Delta logo]()
$502
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/95:56 pm
DSM
- ORD
1 stop3h 51m
Delta
Wed 8/196:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 7/26![Delta logo]()
$512
Last-minute flights from Des Moines to IllinoisDiscover last-minute flight deals from Des Moines to Illinois. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Illinois. Data last updated July 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:49 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Mon 8/248:26 am
ORD
- DSM
Nonstop1h 30m
American Airlines
Deal found 7/28![American Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 8/248:50 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/28![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:00 am
DSM
- STL
1 stop5h 55m
American Airlines
Sat 8/298:06 pm
STL
- DSM
1 stop4h 29m
American Airlines
Deal found 7/25![American Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
DSM
- STL
2 stops7h 05m
Southwest
Sat 8/298:25 am
STL
- DSM
1 stop3h 05m
Southwest
Deal found 7/25![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
DSM
- MDW
Nonstop1h 15m
Southwest
Sat 8/296:50 am
MDW
- DSM
1 stop7h 20m
Southwest
Deal found 7/27![Southwest logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:19 pm
DSM
- ORD
1 stop23h 17m
Multiple Airlines
Thu 8/276:00 am
ORD
- DSM
1 stop13h 54m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$241
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:56 pm
DSM
- ORD
1 stop3h 51m
Delta
Mon 8/311:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Deal found 7/27![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- STL
2 stops8h 15m
Southwest
Tue 9/12:50 pm
STL
- DSM
2 stops6h 10m
Southwest
Deal found 7/28![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:15 am
DSM
- MDW
2 stops9h 45m
Southwest
Thu 8/2710:05 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 7/28![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- ORD
Nonstop1h 36m
United Airlines
Sat 8/297:55 pm
ORD
- DSM
Nonstop1h 28m
United Airlines
Deal found 7/27![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
- ORD
1 stop4h 42m
Delta
Mon 8/311:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Deal found 7/24![Delta logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:55 pm
DSM
- ORD
1 stop17h 34m
Multiple Airlines
Wed 9/28:05 am
ORD
- DSM
2 stops35h 52m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$245
One-way flights from Des Moines to IllinoisSearch for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:29 am
DSM
- RFD
1 stop5h 34m
Allegiant Air
Deal found 7/26![Allegiant Air logo]()
$101
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:10 am
DSM
- STL
1 stop3h 25m
Southwest
Deal found 7/25![Southwest logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:43 am
DSM
- ORD
1 stop9h 41m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm
DSM
- ORD
1 stop23h 32m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
DSM
- ORD
1 stop6h 50m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
- ORD
1 stop23h 32m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:29 am
DSM
- RFD
1 stop5h 34m
Allegiant Air
Deal found 7/27![Allegiant Air logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:55 pm
DSM
- ORD
1 stop17h 34m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$116
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:40 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 7/27![Southwest logo]()
$119
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/243:20 pm
DSM
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/25![United Airlines logo]()
$119
This Frontier deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:51 pm
DSM
- ORD
1 stop6h 44m
Frontier
Deal found 7/24![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:37 pm
DSM
- ORD
1 stop11h 56m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$121
Find flight deals from Des Moines to Illinois
Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $207 (Kiwi.com) |
One-way from | $101 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $448 |
Good round-trip deal | $378 or less |
Good one-way deal | $203 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 9/17
5:40 am-9:15 am
1 stop3h 35m
Lambert-St Louis
Sat 9/19
8:25 am-11:30 am
1 stop3h 05m
$209
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/8
3:22 pm-10:00 pm
1 stop6h 38m
Lambert-St Louis
Tue 9/15
8:00 am-2:20 pm
1 stop6h 20m
$209
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 9/10
7:00 am-10:23 am
1 stop3h 23m
Lambert-St Louis
Thu 9/17
6:15 am-10:17 am
1 stop4h 02m
$209
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/8
2:40 pm-5:55 pm
1 stop3h 15m
Lambert-St Louis
Tue 9/15
3:05 pm-10:00 pm
2 stops6h 55m
$214
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 8/25
6:10 am-9:35 am
1 stop3h 25m
Lambert-St Louis
Tue 9/1
2:50 pm-9:00 pm
2 stops6h 10m
$214
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 9/10
5:40 am-9:15 am
1 stop3h 35m
Lambert-St Louis
Thu 9/17
6:05 am-11:25 am
1 stop5h 20m
$232
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Sat 10/3
6:55 pm-8:33 pm
Nonstop1h 38m
Chicago O'Hare Intl
Sat 10/17
11:00 am-12:32 pm
Nonstop1h 32m
$237
Quickest round-trip
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Thu 9/10
3:50 pm-5:10 pm
Nonstop1h 20m
Chicago Midway
Thu 9/17
8:50 pm-10:15 pm
Nonstop1h 25m
$237
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Wed 9/9
6:10 am-7:30 am
Nonstop1h 20m
Chicago Midway
Wed 9/16
8:35 pm-10:00 pm
Nonstop1h 25m
$237
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Wed 8/26
7:15 am-5:00 pm
2 stops9h 45m
Chicago Midway
Mon 8/31
8:50 pm-10:10 pm
Nonstop1h 20m
$252
Showing 1-10 of 59 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
DSM-STL
DSM-ORD
DSM-MDW
DSM-RFD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Illinois
DSM-USIL
DSM-STL
DSM-ORD
DSM-MDW
DSM-RFD
What is the cheapest month to book a flight from Des Moines to Illinois?
Currently, October is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $237). Flying from Des Moines to Illinois in July is currently the most expensive (average of $419). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IL?
Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2026.
One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 42% on airfare.
Weekly flight availability from Des Moines to Illinois
Explore weekly flight availability from Des Moines to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2026.
The most flights from DSM to USIL are scheduled on a Tuesday (45 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (13 on average).
How much does it cost to fly round-trip from Des Moines to Illinois?
Airfare is below average for this route at the moment.
Des Moines to Illinois flights typically cost between $295 and $409 in September.The cheapest round-trip price found within the last 5 days was $207 on Multiple Airlines (Sep 6-Sep 10).
How far ahead should I book a flight from Des Moines to Illinois?
The best time to book flights from Des Moines to Illinois is 18 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Des Moines to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Des Moines to Illinois. Price data was last updated on July 25, 2026.
Travelers seeking maximum savings on their Des Moines to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated July 29, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Entertainment
7.5
Overall
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Des Moines and Illinois flights
Browse other Des Moines and Illinois flight options. Last updated on July 29, 2026.
Popular flight searches
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Des Moines to Illinois flights
Consider these flights traveling from Des Moines to Illinois.
Top 2 airlines flying from Des Moines to Illinois
Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$285 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$324 | FlexibilityNo cancel fee | On-time69% |