$90+ Cheap flights from Des Moines (DSM) to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ORD
Jun 1 — Jun 81
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IllinoisExplore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 2, 2026.
Explore the most affordable flight options available from Des Moines to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:44 pm
DSM
- ORD
1 stop17h 40m
Multiple Airlines
Sat 6/138:00 pm
ORD
- DSM
1 stop26h 52m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$223
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:16 pm
DSM
- ORD
1 stop6h 16m
Frontier
Tue 6/99:48 pm
ORD
- DSM
1 stop15h 43m
Frontier
Deal found 4/28![Frontier logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:16 pm
DSM
- ORD
1 stop6h 16m
Multiple Airlines
Thu 6/46:55 am
ORD
- DSM
2 stops16h 03m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:16 pm
DSM
- ORD
1 stop6h 16m
Multiple Airlines
Sat 6/67:52 pm
ORD
- DSM
1 stop27h 00m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$236
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:15 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 6/109:20 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 4/29![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:43 am
DSM
- ORD
Nonstop1h 49m
American Airlines
Wed 6/1011:45 am
ORD
- DSM
Nonstop1h 36m
American Airlines
Deal found 4/30![American Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:18 am
DSM
- ORD
Nonstop1h 42m
American Airlines
Tue 6/2311:00 pm
ORD
- DSM
Nonstop1h 35m
American Airlines
Deal found 5/2![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- ORD
1 stop6h 16m
Multiple Airlines
Fri 5/298:05 am
ORD
- DSM
1 stop15h 19m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Thu 7/1611:27 am
RFD
- DSM
2 stops29h 13m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:16 pm
DSM
- STL
1 stop29h 07m
Multiple Airlines
Sun 6/76:33 pm
STL
- DSM
2 stops28h 54m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Sun 7/1211:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$247
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:15 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Thu 6/410:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 4/29![Southwest logo]()
$253
Best flights from Des Moines to IllinoisDiscover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 2, 2026.
Discover carefully curated flight deals from Des Moines to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 2, 2026.
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:15 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 6/1010:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 5/2![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:45 pm
DSM
- MDW
1 stop3h 33m
Delta
Tue 6/239:54 am
MDW
- DSM
1 stop4h 11m
Delta
Deal found 5/2![Delta logo]()
$257
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:10 pm
DSM
- ORD
Nonstop2h 00m
American Airlines
Thu 5/284:56 pm
ORD
- DSM
Nonstop1h 40m
American Airlines
Deal found 4/27![American Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Mon 7/137:50 pm
RFD
- DSM
1 stop19h 34m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$271
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
DSM
- STL
1 stop4h 13m
United Airlines
Sun 8/306:00 am
STL
- DSM
1 stop4h 11m
United Airlines
Deal found 5/2![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:03 pm
DSM
- ORD
1 stop3h 22m
Delta
Wed 6/2412:27 pm
ORD
- DSM
1 stop4h 27m
Delta
Deal found 5/1![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:25 am
DSM
- MDW
Nonstop1h 20m
Southwest
Thu 6/410:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 4/30![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/162:45 pm
DSM
- ORD
1 stop6h 40m
Delta
Tue 6/238:36 am
ORD
- DSM
1 stop5h 29m
Delta
Deal found 5/2![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:40 pm
DSM
- STL
2 stops7h 30m
Southwest
Wed 9/166:30 am
STL
- DSM
1 stop5h 20m
Southwest
Deal found 5/1![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:26 am
DSM
- ORD
1 stop6h 03m
Delta
Thu 6/46:24 am
ORD
- DSM
1 stop3h 52m
Delta
Deal found 4/30![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1711:00 am
DSM
- RFD
1 stop21h 29m
Allegiant Air
Wed 6/2410:07 am
RFD
- DSM
1 stop22h 30m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$346
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:35 am
DSM
- STL
1 stop4h 55m
Southwest
Sat 6/65:40 am
STL
- DSM
1 stop5h 55m
Southwest
Deal found 4/29![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:01 am
DSM
- STL
1 stop3h 31m
Delta
Tue 6/28:53 am
STL
- DSM
1 stop3h 31m
Delta
Deal found 4/28![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:10 am
DSM
- STL
2 stops10h 15m
Southwest
Sun 8/306:00 am
STL
- DSM
1 stop5h 35m
Southwest
Deal found 5/2![Southwest logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 am
DSM
- RFD
1 stop11h 59m
Allegiant Air
Fri 7/178:39 am
RFD
- DSM
1 stop13h 36m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$380
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:08 am
DSM
- MDW
1 stop6h 33m
Delta
Wed 6/179:54 am
MDW
- DSM
1 stop4h 11m
Delta
Deal found 4/28![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Tue 9/223:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 4/29![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:50 am
DSM
- ORD
1 stop14h 54m
United Airlines
Thu 6/48:52 am
ORD
- DSM
Nonstop1h 35m
United Airlines
Deal found 4/29![United Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:00 am
DSM
- RFD
1 stop13h 20m
Allegiant Air
Wed 6/1710:07 am
RFD
- DSM
1 stop22h 30m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$396
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:08 am
DSM
- ORD
1 stop6h 32m
Delta
Wed 6/176:30 am
ORD
- DSM
1 stop3h 44m
Delta
Deal found 4/28![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:15 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Fri 5/2910:05 am
MDW
- DSM
2 stops8h 30m
Southwest
Deal found 5/1![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:00 am
DSM
- ORD
Nonstop1h 41m
United Airlines
Thu 5/287:05 am
ORD
- DSM
1 stop9h 10m
United Airlines
Deal found 4/27![United Airlines logo]()
$487
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:08 am
DSM
- ORD
1 stop6h 52m
Delta
Wed 7/812:27 pm
ORD
- DSM
1 stop4h 25m
Delta
Deal found 5/1![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:30 am
DSM
- RFD
1 stop11h 53m
Allegiant Air
Fri 6/58:35 am
RFD
- DSM
1 stop9h 53m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$418
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:30 am
DSM
- STL
1 stop6h 00m
Southwest
Wed 5/273:10 pm
STL
- DSM
2 stops7h 00m
Southwest
Deal found 4/30![Southwest logo]()
$316
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:03 pm
DSM
- ORD
1 stop3h 22m
Delta
Tue 6/166:30 am
ORD
- DSM
1 stop3h 44m
Delta
Deal found 5/2![Delta logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:30 am
DSM
- RFD
1 stop11h 53m
Allegiant Air
Mon 7/137:50 pm
RFD
- DSM
1 stop19h 34m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$420
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Fri 6/1910:05 pm
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 5/2![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:04 pm
DSM
- STL
2 stops8h 05m
Delta
Fri 6/51:59 pm
STL
- DSM
1 stop6h 37m
Delta
Deal found 5/1![Delta logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:00 am
DSM
- RFD
1 stop13h 20m
Allegiant Air
Mon 6/157:53 pm
RFD
- DSM
1 stop19h 28m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$432
Last-minute flights from Des Moines to IllinoisDiscover last-minute flight deals from Des Moines to Illinois. Data last updated May 2, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Illinois. Data last updated May 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:02 pm
DSM
- ORD
Nonstop1h 48m
American Airlines
Mon 5/2511:40 am
ORD
- DSM
Nonstop1h 38m
American Airlines
Deal found 4/28![American Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:48 pm
DSM
- ORD
Nonstop1h 43m
American Airlines
Tue 5/2610:31 pm
ORD
- DSM
Nonstop1h 37m
American Airlines
Deal found 4/29![American Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:35 am
DSM
- MDW
Nonstop1h 20m
Southwest
Mon 5/2510:20 am
MDW
- DSM
Nonstop1h 25m
Southwest
Deal found 5/1![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:10 pm
DSM
- ORD
Nonstop2h 00m
American Airlines
Thu 5/2811:40 am
ORD
- DSM
Nonstop1h 38m
American Airlines
Deal found 4/29![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:50 pm
DSM
- ORD
Nonstop1h 39m
United Airlines
Tue 6/29:38 pm
ORD
- DSM
Nonstop1h 38m
United Airlines
Deal found 4/27![United Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
DSM
- ORD
1 stop6h 46m
Delta
Tue 6/26:24 am
ORD
- DSM
1 stop3h 52m
Delta
Deal found 4/27![Delta logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:25 pm
DSM
- ORD
1 stop30h 48m
Multiple Airlines
Tue 6/29:37 pm
ORD
- DSM
1 stop15h 54m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:16 pm
DSM
- ORD
1 stop6h 16m
Multiple Airlines
Fri 5/298:05 am
ORD
- DSM
1 stop15h 19m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$240
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:30 am
DSM
- MDW
Nonstop1h 25m
Southwest
Thu 5/289:45 pm
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 4/29![Southwest logo]()
$253
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- ORD
1 stop3h 47m
Delta
Thu 5/282:00 pm
ORD
- DSM
1 stop6h 36m
Delta
Deal found 4/29![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:57 pm
DSM
- ORD
2 stops15h 58m
Multiple Airlines
Sat 5/307:52 pm
ORD
- DSM
1 stop26h 39m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:00 am
DSM
- ORD
Nonstop1h 43m
American Airlines
Mon 6/110:31 pm
ORD
- DSM
Nonstop1h 37m
American Airlines
Deal found 5/2![American Airlines logo]()
$275
One-way flights from Des Moines to IllinoisSearch for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated May 2, 2026.
Search for one-way flight options from Des Moines to Illinois. Find affordable one-way fares based on user searches. Data last updated May 2, 2026.
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- ORD
1 stop6h 16m
Frontier
Deal found 4/27![Frontier logo]()
$90
This Expedia deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Deal found 4/30![Frontier logo]()
$111
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:16 pm
DSM
- ORD
1 stop6h 27m
Frontier
Deal found 4/29![Frontier logo]()
$115
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:16 pm
DSM
- ORD
1 stop6h 27m
Frontier
Deal found 4/28![Frontier logo]()
$116
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Deal found 4/28![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:45 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 4/28![Southwest logo]()
$119
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:48 pm
DSM
- ORD
Nonstop1h 43m
American Airlines
Deal found 4/30![American Airlines logo]()
$119
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:18 am
DSM
- ORD
Nonstop1h 42m
American Airlines
Deal found 5/2![American Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:02 pm
DSM
- ORD
1 stop25h 45m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:16 pm
DSM
- ORD
1 stop30h 27m
Frontier
Deal found 5/1![Frontier logo]()
$126
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- MDW
1 stop4h 52m
Delta
Deal found 4/28![Delta logo]()
$129
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:04 pm
DSM
- ORD
1 stop3h 47m
Delta
Deal found 4/28![Delta logo]()
$129
Find flight deals from Des Moines to Illinois
Keep the following information in mind while searching for Des Moines to Illinois flight deals. Data was last updated May 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $223 (Kiwi.com) |
One-way from | $90 (Frontier) |
Popular in | April |
Cheapest in | September |
Average price | $257 |
Good round-trip deal | $386 or less |
Good one-way deal | $225 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 2, 2026.
Use the filters below to find and compare flights from Des Moines to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Wed 6/3
3:15 pm-4:35 pm
Nonstop1h 20m
Chicago Midway
Wed 6/10
10:10 am-11:30 am
Nonstop1h 20m
$253
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Tue 6/16
2:45 pm-6:18 pm
1 stop3h 33m
Chicago Midway
Tue 6/23
9:54 am-2:05 pm
1 stop4h 11m
$257
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Wed 6/17
6:03 pm-9:25 pm
1 stop3h 22m
Chicago O'Hare Intl
Wed 6/24
12:27 pm-4:54 pm
1 stop4h 27m
$257
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Tue 6/16
2:45 pm-9:25 pm
1 stop6h 40m
Chicago O'Hare Intl
Tue 6/23
8:36 am-2:05 pm
1 stop5h 29m
$257
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Mon 5/25
7:10 pm-9:10 pm
Nonstop2h 00m
Chicago O'Hare Intl
Thu 5/28
4:56 pm-6:36 pm
Nonstop1h 40m
$269
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Thu 5/28
5:25 am-6:45 am
Nonstop1h 20m
Chicago Midway
Thu 6/4
10:05 pm-11:30 pm
Nonstop1h 25m
$269
Des MoinesChicago
DSM - RFD
DSMRFD
Des Moines
Wed 7/1
10:59 am-8:29 am
1 stop21h 30m
Chicago Greater Rockford
Mon 7/13
7:50 pm-3:24 pm
1 stop19h 34m
$271
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Tue 6/2
10:26 am-4:29 pm
1 stop6h 03m
Chicago O'Hare Intl
Thu 6/4
6:24 am-10:16 am
1 stop3h 52m
$273
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 5/26
7:01 am-10:32 am
1 stop3h 31m
Lambert-St Louis
Tue 6/2
8:53 am-12:24 pm
1 stop3h 31m
$279
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/15
2:40 pm-10:10 pm
2 stops7h 30m
Lambert-St Louis
Wed 9/16
6:30 am-11:50 am
1 stop5h 20m
$284
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Des Moines with our price prediction graph.
DSM-ORD
DSM-STL
DSM-MDW
DSM-RFD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Illinois
DSM-USIL
DSM-ORD
DSM-STL
DSM-MDW
DSM-RFD
How far ahead should I book a flight from Des Moines to Illinois?
The best time to book flights from Des Moines to Illinois is 90 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Des Moines to Illinois?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Illinois (average of $126). Flying from Des Moines to Illinois in January is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IL?
Find hourly flight availability from Des Moines to Illinois. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 2, 2026.
One of the essential ways to save on airfare from Des Moines to Illinois is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 39% on airfare.
What is the cheapest day to fly from Des Moines to Illinois?
Use this chart to determine the cheapest time to fly round-trip from Des Moines to Illinois. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Des Moines to Illinois flight should consider departing on Wednesday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Des Moines to Illinois
Explore weekly flight availability from Des Moines to Illinois. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 2, 2026.
The most flights from DSM to USIL are scheduled on a Saturday (58 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (38 on average).
How much does it cost to fly round-trip from Des Moines to Illinois?
Reviews of airlines servicing Illinois
Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated May 2, 2026.
Get a feel of what it's like to fly with Southwest,United Airlines, andAmerican Airlines from Des Moines to Illinois by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Des Moines and Illinois flights
Browse other Des Moines and Illinois flight options. Last updated on May 2, 2026.
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Des Moines to Illinois flights
Consider these flights traveling from Des Moines to Illinois.
Top 2 airlines flying from Des Moines to Illinois
Discover the top 2 airlines that operate flights from Des Moines to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$148 | Average$248 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$276 | FlexibilityNo cancel fee | On-time69% |