$116+ Cheap flights from Illinois to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — DSM
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Illinois to Des MoinesExplore the most affordable flight options available from Illinois to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Illinois to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 am -
1 stop7h 45m
Sat 12/55:20 am -
1 stop6h 20m
Deal found 9/16![Southwest logo]()
$235
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:35 am -
1 stop7h 05m
Sat 10/315:20 am -
1 stop5h 45m
Deal found 9/13![Southwest logo]()
$236
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:40 pm -
Nonstop1h 34m
Tue 10/207:31 pm -
Nonstop1h 38m
Deal found 9/16![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:41 pm -
1 stop22h 01m
Mon 10/128:25 pm -
1 stop27h 59m
Deal found 9/15![Multiple Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:25 pm -
Nonstop1h 25m
Sat 10/171:20 pm -
Nonstop1h 20m
Deal found 9/13![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:17 am -
Nonstop1h 39m
Mon 10/122:01 pm -
Nonstop1h 38m
Deal found 9/15![American Airlines logo]()
$256
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:40 am -
Nonstop1h 20m
Mon 10/125:10 am -
Nonstop1h 20m
Deal found 9/15![Southwest logo]()
$256
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:25 pm -
Nonstop1h 25m
Mon 10/265:10 am -
Nonstop1h 20m
Deal found 9/14![Southwest logo]()
$257
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:40 pm -
Nonstop1h 34m
Thu 10/227:29 am -
Nonstop1h 41m
Deal found 9/15![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:27 pm -
1 stop6h 47m
Thu 10/227:31 pm -
1 stop4h 48m
Deal found 9/15![American Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:29 am -
1 stop6h 01m
Fri 10/237:31 pm -
1 stop4h 48m
Deal found 9/16![American Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:25 pm -
Nonstop1h 25m
Mon 10/197:10 pm -
1 stop5h 10m
Deal found 9/13![Southwest logo]()
$267
Best flights from Illinois to Des MoinesDiscover carefully curated flight deals from Illinois to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Illinois to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:20 pm -
2 stops7h 45m
Sat 12/55:20 am -
2 stops7h 20m
Deal found 9/16![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:12 pm -
1 stop7h 03m
Wed 10/215:22 pm -
1 stop6h 22m
Deal found 9/16![United Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:22 pm -
1 stop3h 51m
Sat 11/2111:00 am -
1 stop5h 41m
Deal found 9/16![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:25 pm -
Nonstop1h 25m
Mon 10/265:10 am -
Nonstop1h 20m
Deal found 9/14![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:45 am -
Nonstop1h 25m
Thu 10/297:10 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$283
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:25 pm -
Nonstop1h 30m
Mon 11/26:45 pm -
Nonstop1h 40m
Deal found 9/16![United Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:00 pm -
Nonstop1h 35m
Mon 10/128:00 am -
Nonstop1h 36m
Deal found 9/14![United Airlines logo]()
$326
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:55 am -
Nonstop1h 25m
Wed 10/215:35 am -
Nonstop1h 20m
Deal found 9/14![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 am -
1 stop3h 51m
Wed 10/213:46 pm -
1 stop5h 41m
Deal found 9/14![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:35 pm -
1 stop6h 15m
Sat 11/215:55 pm -
1 stop7h 00m
Deal found 9/15![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 am -
1 stop4h 34m
Tue 10/2011:27 am -
1 stop4h 16m
Deal found 9/12![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:20 am -
1 stop3h 51m
Tue 10/2010:57 am -
1 stop5h 43m
Deal found 9/13![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:35 pm -
Nonstop1h 25m
Thu 10/227:10 pm -
1 stop5h 10m
Deal found 9/15![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:30 pm -
1 stop3h 41m
Tue 11/34:01 pm -
1 stop5h 26m
Deal found 9/12![Delta logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:30 pm -
1 stop4h 25m
Sat 11/148:00 am -
1 stop5h 53m
Deal found 9/13![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:05 pm -
2 stops10h 10m
Sun 11/15:25 am -
2 stops8h 40m
Deal found 9/15![Southwest logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:50 pm -
Nonstop1h 25m
Wed 10/2111:27 am -
Nonstop1h 39m
Deal found 9/14![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:40 am -
Nonstop1h 20m
Mon 10/127:10 pm -
1 stop5h 10m
Deal found 9/14![Southwest logo]()
$342
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:50 pm -
Nonstop1h 25m
Sat 10/246:55 pm -
Nonstop1h 38m
Deal found 9/13![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:00 am -
1 stop4h 11m
Sun 10/116:55 am -
2 stops5h 46m
Deal found 9/15![Delta logo]()
$514
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:50 pm -
1 stop5h 20m
Mon 10/54:30 pm -
1 stop6h 50m
Deal found 9/13![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:20 pm -
Nonstop1h 28m
Sat 10/173:11 pm -
Nonstop1h 43m
Deal found 9/13![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:55 am -
2 stops8h 55m
Sat 10/315:20 am -
2 stops8h 25m
Deal found 9/13![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:15 am -
1 stop6h 19m
Sat 10/31:26 pm -
1 stop5h 35m
Deal found 9/14![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:50 pm -
1 stop5h 15m
Sat 11/215:20 am -
2 stops9h 35m
Deal found 9/16![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop9h 21m
Tue 10/206:55 pm -
Nonstop1h 38m
Deal found 9/16![United Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:50 pm -
1 stop5h 20m
Sat 10/315:20 am -
1 stop5h 45m
Deal found 9/12![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:55 pm -
Nonstop1h 28m
Mon 10/56:00 am -
Nonstop1h 41m
Deal found 9/16![United Airlines logo]()
$440
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:20 pm -
2 stops6h 55m
Mon 10/127:10 pm -
1 stop4h 40m
Deal found 9/12![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:05 am -
Nonstop1h 25m
Sun 11/224:25 pm -
Nonstop1h 20m
Deal found 9/11![Southwest logo]()
$379
Last-minute flights from Illinois to Des MoinesDiscover last-minute flight deals from Illinois to Des Moines. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to Des Moines. Data last updated September 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:41 pm -
1 stop22h 01m
Mon 10/128:25 pm -
1 stop27h 59m
Deal found 9/15![Multiple Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:25 pm -
Nonstop1h 25m
Sat 10/171:20 pm -
Nonstop1h 20m
Deal found 9/13![Southwest logo]()
$248
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:17 am -
Nonstop1h 39m
Mon 10/122:01 pm -
Nonstop1h 38m
Deal found 9/15![American Airlines logo]()
$256
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:40 am -
Nonstop1h 20m
Mon 10/125:10 am -
Nonstop1h 20m
Deal found 9/15![Southwest logo]()
$256
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:55 pm -
Nonstop1h 28m
Mon 10/193:11 pm -
Nonstop1h 43m
Deal found 9/14![United Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:40 pm -
Nonstop1h 34m
Thu 10/227:29 am -
Nonstop1h 41m
Deal found 9/15![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1710:40 pm -
Nonstop1h 34m
Tue 10/207:31 pm -
Nonstop1h 38m
Deal found 9/16![American Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:29 am -
1 stop6h 01m
Fri 10/237:31 pm -
1 stop4h 48m
Deal found 9/16![American Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sat 10/177:25 pm -
Nonstop1h 25m
Mon 10/197:10 pm -
1 stop5h 10m
Deal found 9/13![Southwest logo]()
$267
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/195:27 pm -
1 stop6h 47m
Thu 10/227:31 pm -
1 stop4h 48m
Deal found 9/15![American Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:35 am -
1 stop7h 05m
Sat 10/315:20 am -
1 stop5h 45m
Deal found 9/13![Southwest logo]()
$236
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:25 pm -
Nonstop1h 25m
Mon 10/265:10 am -
Nonstop1h 20m
Deal found 9/14![Southwest logo]()
$257
One-way flights from Illinois to Des MoinesSearch for one-way flight options from Illinois to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Illinois to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:41 pm -
1 stop21h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$116
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:26 am -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$120
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:05 am -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$120
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:55 am -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$122
This CheapOair deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:30 am -
1 stop13h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$128
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:35 pm -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Southwest logo]()
$129
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:20 am -
1 stop3h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$130
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:27 pm -
1 stop6h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Delta logo]()
$130
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:29 am -
1 stop6h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![American Airlines logo]()
$133
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:00 am -
Nonstop1h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$137
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:50 pm -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$137
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop28h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$139
Find flight deals from Illinois to Des Moines
Keep the following information in mind while searching for Illinois to Des Moines flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $236 (Southwest) |
One-way from | $116 (Kiwi.com) |
Popular in | August |
Cheapest in | February |
Average price | $329 |
Good round-trip deal | $291 or less |
Good one-way deal | $108 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Illinois to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Sat 10/31
4:25 pm-5:45 pm
Nonstop1h 20m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Wed 11/18
6:23 am-10:19 am
1 stop3h 56m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Wed 10/14
12:27 pm-7:11 pm
1 stop6h 44m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Thu 10/15
9:50 pm-11:15 pm
Nonstop1h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Tue 10/13
10:00 pm-11:35 pm
Nonstop1h 35m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Fri 10/9
9:50 pm-11:15 pm
Nonstop1h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Tue 12/22
9:55 am-11:15 am
Nonstop1h 20m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Fri 10/16
6:20 am-10:11 am
1 stop3h 51m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
ChicagoDes Moines
MDW Chicago Midway - DSM Des Moines
MDWDSM
Chicago Midway
Fri 12/11
2:35 pm-10:00 pm
1 stop7h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
ChicagoDes Moines
ORD Chicago O'Hare Intl - DSM Des Moines
ORDDSM
Chicago O'Hare Intl
Mon 10/12
9:00 am-10:31 am
Nonstop1h 31m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$172
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Illinois with our price prediction graph.
STL-DSM
MDW-DSM
ORD-DSM
PIA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to Des Moines
USIL-DSM
STL-DSM
MDW-DSM
ORD-DSM
PIA-DSM
What is the cheapest month to book a flight from Illinois to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Illinois to Des Moines (average of $300). Flying from Illinois to Des Moines in August is currently the most expensive (average of $538). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to DSM?
Find hourly flight availability from Illinois to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
A simple way to save on the total cost of your ticket is to fly from Illinois to Des Moines at noon. If you’re flexible enough to do this you can expect to save up to 51% on your trip compared to booking a flight in the afternoon.
Weekly flight availability from Illinois to Des Moines
Explore weekly flight availability from Illinois to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 17, 2026.
The most flights from USIL to DSM are scheduled on a Monday (44 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (27 on average).
How much does it cost to fly round-trip from Illinois to Des Moines?
Airfare is below average for this route at the moment.
Illinois to Des Moines flights typically cost between $273 and $511 in October.The cheapest round-trip price found within the last 5 days was $239 on American Airlines (Oct 17-Oct 20).
What is the cheapest day to fly from Illinois to Des Moines?
Use this chart to determine the cheapest time to fly round-trip from Illinois to Des Moines. Price data was last updated on September 12, 2026.
Travelers seeking maximum savings on their Illinois to Des Moines flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Illinois to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
West Des Moines
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 17, 2026.
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Illinois and Des Moines flights
Browse other Illinois and Des Moines flight options. Last updated on September 17, 2026.
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Illinois to Des Moines flights
Consider these flights traveling from Illinois to Des Moines.
Top 3 airlines flying from Illinois to Des Moines
Discover the top 3 airlines that operate flights from Illinois to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$189 | Average$439 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$209 | Average$419 | FlexibilityNo cancel fee | On-time63% |