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Des Moines

$49+ Cheap flights from St. Louis to Des Moines (STL - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheap flight deals from St. Louis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 30, 2025.

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Popular in

March

Cheapest in

June

Average price

$213

Good one-way deal

$184 or less
From Lambert-St Louis to Des Moines
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One-way flight from Lambert-St Louis to Des Moines
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a one-way flight from Lambert-St Louis to Des Moines.
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Find flight deals from St. Louis to Des Moines

Cheapest flights from St. Louis to Des Moines
Explore the most affordable flight options available from St. Louis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:00 amSTL - DSM
Nonstop1h 05mSouthwest
Mon 9/295:30 pmDSM - STL
Nonstop1h 05mSouthwest
Deal found 6/30$97
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:03 pmSTL - DSM
1 stop3h 25mAmerican Airlines
Mon 9/296:09 pmDSM - STL
1 stop5h 39mAmerican Airlines
Deal found 6/29$159
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/115:11 pmSTL - DSM
1 stop5h 28mDelta
Tue 8/127:00 amDSM - STL
1 stop3h 36mDelta
Deal found 6/30$167
This Mytrip deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/109:50 amSTL - DSM
2 stops12h 48mMultiple Airlines
Mon 7/142:00 pmDSM - STL
3 stops26h 31mMultiple Airlines
Deal found 6/28$313
This Booking.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/148:44 pmSTL - DSM
2 stops22h 04mFrontier
Thu 8/213:23 pmDSM - STL
2 stops21h 33mFrontier
Deal found 6/30$378
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/127:55 amSTL - DSM
1 stop6h 49mUnited Airlines
Tue 7/156:50 pmDSM - STL
1 stop3h 55mUnited Airlines
Deal found 6/28$393

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from St. Louis to Des Moines that are best for you.

Fly from

St. Louis

Fly to

Des Moines

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 9/25

10:00 am-11:05 am

Nonstop1h 05m

Des Moines

Mon 9/29

5:30 pm-6:35 pm

Nonstop1h 05m

$97

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 9/25

8:03 pm-11:28 pm

1 stop3h 25m

Des Moines

Mon 9/29

6:09 pm-11:48 pm

1 stop5h 39m

$159

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 8/11

5:11 pm-10:39 pm

1 stop5h 28m

Des Moines

Tue 8/12

7:00 am-10:36 am

1 stop3h 36m

$167

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 7/10

9:50 am-10:38 pm

2 stops12h 48m

Des Moines

Mon 7/14

2:00 pm-4:31 pm

3 stops26h 31m

$313

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 8/14

8:44 pm-6:48 pm

2 stops22h 04m

Des Moines

Thu 8/21

3:23 pm-12:56 pm

2 stops21h 33m

$378

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 7/12

7:55 am-2:44 pm

1 stop6h 49m

Des Moines

Tue 7/15

6:50 pm-10:45 pm

1 stop3h 55m

$393

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 9/1

9:40 pm-10:50 pm

Nonstop1h 10m

$49

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 9/1

7:59 pm-11:24 pm

1 stop3h 25m

$80

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Sat 8/30

5:30 pm-9:45 pm

1 stop4h 15m

$84

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 8/12

6:40 am-5:10 pm

2 stops10h 30m

$89

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 11 results
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Best time to book a flight from St. Louis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Des Moines

What is the cheapest month to book a flight from St. Louis to Des Moines?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Des Moines (average of $336). Flying from St. Louis to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to DSM?

Find hourly flight availability from St. Louis to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

When flying from St. Louis to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 39% versus a flight in the morning.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 30, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from St. Louis to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,278 reviews
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,973 reviews
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,852 reviews
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,290 reviews
Southwest
8.0
Very good
4,278 reviews

Comfort

8.0

Boarding

8.2

Food

7.0

Crew

8.6

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from St. Louis to Des Moines?

    To fly from St. Louis to Des Moines, you need to book a flight from Lambert-St Louis (STL) to Des Moines (DSM). Nonstop flights to Des Moines from Lambert-St Louis take 1h 05m on average. When it comes time to book airfare, you have a few options: there is 1 outbound flight from Lambert-St Louis to Des Moines offered by 1 airline.

  • How popular is this St. Louis to Des Moines flight route?

    The Lambert-St Louis to Des Moines flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from St. Louis to Des Moines round-trip?

    Flying on Southwest is currently your cheapest option to Des Moines, with prices starting at $97. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $159 and $167, respectively. Southwest is currently priced 72% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from St. Louis to Des Moines one-way?

    The cheapest airlines for a one-way flight from St. Louis to Des Moines are Southwest ($49), American Airlines ($80), and United Airlines ($84).

  • What are the cheapest flights from St. Louis to Des Moines?

    On average you can expect to pay $199 for a flight from St. Louis to Des Moines. The cheapest flight overall is $165 while the most popular route, (Lambert-St Louis - Des Moines) is currently priced at $167.

  • Can I find deals for flights from St. Louis to Des Moines that include hotel bookings?

    Yes. In addition to deals on St. Louis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Des Moines.

  • Can I find deals for business class flights from St. Louis to Des Moines?

    Yes. Cheapflights offers flight deals from St. Louis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to Des Moines (average of $336). Flying from St. Louis to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top airline flying from St. Louis to Des Moines

Discover the top airline that operate flights from St. Louis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$159Average$315FlexibilityNo cancel feeOn-time63%

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