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$101+ Cheap flights from Des Moines (DSM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from Des Moines to Indiana

Cheapest flights from Des Moines to Indiana
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm
DSM
-
ORD
1 stop23h 32m
Multiple Airlines
Thu 9/177:25 am
ORD
-
DSM
1 stop12h 32m
Multiple Airlines
Deal found 7/27$230
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
-
MDW
Nonstop1h 20m
Southwest
Mon 8/248:50 pm
MDW
-
DSM
Nonstop1h 20m
Southwest
Deal found 7/27$237
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
DSM
-
ORD
Nonstop1h 36m
United Airlines
Sat 8/297:55 pm
ORD
-
DSM
Nonstop1h 28m
United Airlines
Deal found 7/27$237
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:49 pm
DSM
-
ORD
Nonstop1h 48m
American Airlines
Mon 8/248:26 am
ORD
-
DSM
Nonstop1h 30m
American Airlines
Deal found 7/26$238
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:55 am
DSM
-
ORD
Nonstop1h 50m
American Airlines
Tue 9/156:59 am
ORD
-
DSM
Nonstop1h 40m
American Airlines
Deal found 7/24$239
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:19 pm
DSM
-
ORD
1 stop23h 17m
Multiple Airlines
Thu 8/276:00 am
ORD
-
DSM
1 stop13h 54m
Multiple Airlines
Deal found 7/27$241
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am
DSM
-
MDW
Nonstop1h 20m
Southwest
Fri 10/309:45 am
MDW
-
DSM
Nonstop1h 25m
Southwest
Deal found 7/26$242
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am
DSM
-
ORD
Nonstop1h 40m
United Airlines
Fri 10/309:25 pm
ORD
-
DSM
Nonstop1h 25m
United Airlines
Deal found 7/26$242
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/301:55 pm
DSM
-
ORD
1 stop17h 34m
Multiple Airlines
Wed 9/28:05 am
ORD
-
DSM
2 stops35h 52m
Multiple Airlines
Deal found 7/26$245
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
-
MDW
Nonstop1h 20m
Southwest
Tue 9/152:15 pm
MDW
-
DSM
1 stop6h 50m
Southwest
Deal found 7/25$247
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:40 am
DSM
-
MDW
Nonstop1h 20m
Southwest
Mon 9/78:50 pm
MDW
-
DSM
Nonstop1h 25m
Southwest
Deal found 7/24$249
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:15 am
DSM
-
MDW
2 stops9h 45m
Southwest
Wed 9/168:35 pm
MDW
-
DSM
Nonstop1h 25m
Southwest
Deal found 7/27$252

Find flight deals from Des Moines to Indiana

Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$230
(Kiwi.com)

One-way from

$101
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$319
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indiana
Search Deals
One-way flight from Des Moines to Indiana
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Wed 9/9

6:10 am-7:30 am

Nonstop1h 20m

Chicago Midway

Wed 9/16

8:35 pm-10:00 pm

Nonstop1h 25m

$237

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 10/3

6:55 pm-8:33 pm

Nonstop1h 38m

Chicago O'Hare Intl

Sat 10/17

11:00 am-12:32 pm

Nonstop1h 32m

$237

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Thu 9/10

3:50 pm-5:10 pm

Nonstop1h 20m

Chicago Midway

Thu 9/17

8:50 pm-10:15 pm

Nonstop1h 25m

$237

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 10/30

1:05 pm-2:42 pm

Nonstop1h 37m

Chicago O'Hare Intl

Mon 11/2

11:07 am-12:36 pm

Nonstop1h 29m

$242

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 9/8

2:40 pm-4:00 pm

Nonstop1h 20m

Chicago Midway

Tue 9/15

2:15 pm-9:05 pm

1 stop6h 50m

$247

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Sat 8/22

5:30 am-6:45 am

Nonstop1h 15m

Chicago Midway

Sat 8/29

6:50 am-2:10 pm

1 stop7h 20m

$247

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Wed 8/26

7:15 am-5:00 pm

2 stops9h 45m

Chicago Midway

Mon 8/31

8:50 pm-10:10 pm

Nonstop1h 20m

$252

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 9/9

6:00 am-10:37 am

1 stop4h 37m

Chicago O'Hare Intl

Wed 9/16

6:10 am-10:17 am

1 stop4h 07m

$257

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 8/29

6:00 am-10:42 am

1 stop4h 42m

Chicago O'Hare Intl

Mon 8/31

1:59 pm-8:39 pm

1 stop6h 40m

$257

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Thu 8/27

3:50 pm-5:10 pm

Nonstop1h 20m

Chicago Midway

Mon 8/31

2:05 pm-9:15 pm

1 stop7h 10m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Des Moines to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indiana

What is the cheapest month to book a flight from Des Moines to Indiana?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $308). Flying from Des Moines to Indiana in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Indiana?

Airfare is below average for this route at the moment.
Des Moines to Indiana flights typically cost between $341 and $486 in September.
The cheapest round-trip price found within the last 5 days was $249 on Frontier (Sep 14-Sep 20).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated July 28, 2026.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,482 reviews

Crew

8.5

Overall

7.8

Food

7.2

Boarding

8.1

Comfort

7.8

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,482 reviews
Delta
7.8
Good
8,482 reviews

Crew

8.5

Overall

7.8

Food

7.2

Boarding

8.1

Comfort

7.8

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,046 reviews
Delta
7.8
Good
8,482 reviews

Crew

8.5

Overall

7.8

Food

7.2

Boarding

8.1

Comfort

7.8

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,839 reviews
Delta
7.8
Good
8,482 reviews

Crew

8.5

Overall

7.8

Food

7.2

Boarding

8.1

Comfort

7.8

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Indiana?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Indiana from Des Moines.

  • How long is the flight from Des Moines to Indiana?

    A quick flight from Des Moines to Indiana can take about 1h 20m. Southwest provides one of the quickest options available for as low as $237. Airlines will cover a distance of 305 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Des Moines to Indiana?

    While some choose either Des Moines - Chicago Midway or Des Moines - Indianapolis, Des Moines - Chicago O'Hare Intl is the most popular route from Des Moines to Indiana.

  • Can I find deals for flights from Des Moines to Indiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indiana.

  • Can I find deals for business class flights from Des Moines to Indiana?

    Yes. Cheapflights offers flight deals from Des Moines to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indiana?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $308). Flying from Des Moines to Indiana in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Omaha to Denver flights
Omaha to Seattle flights
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Omaha to O'Hare Intl flights
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Omaha to Las Vegas flights
Des Moines to Las Vegas flights
Cedar Rapids to Sky Harbor Intl flights
Omaha to Dallas/Fort Worth flights
Cedar Rapids to Seattle flights
Omaha to Orlando flights
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Cedar Rapids to Orlando flights
Cedar Rapids to Dallas/Fort Worth flights
Moline to Denver flights
Omaha to John F Kennedy Intl flights
Des Moines to Los Angeles flights
Des Moines to Miami flights
Omaha to Atlanta flights
Moline to Dallas/Fort Worth flights
Cedar Rapids to John F Kennedy Intl flights
Cedar Rapids to LaGuardia flights
Omaha to Nashville flights
Cedar Rapids to Newark flights
Omaha to Los Angeles flights
Omaha to LaGuardia flights
Cedar Rapids to Miami flights
Omaha to Miami flights
Des Moines to Sky Harbor Intl flights
Des Moines to O'Hare Intl flights
Des Moines to Reagan-National flights
Omaha to George Bush Intcntl flights
Omaha to Reagan-National flights
Des Moines to Newark flights
Omaha to Sky Harbor Intl flights
Des Moines to Hobby flights
Omaha to Dulles Intl flights
Omaha to Honolulu flights
Des Moines to San Francisco flights
Omaha to San Diego flights
Cedar Rapids to San Diego flights
Moline to Sky Harbor Intl flights
Omaha to Minneapolis flights

Top 3 airlines flying from Des Moines to Indiana

Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$365FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$254Average$311FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$272Average$363FlexibilityNo cancel feeOn-time69%

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