Louisville

$89+ Cheap flights from Des Moines to Louisville (DSM - SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDF
jul. 6 — jul. 131
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Cheap flight deals from Des Moines to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated julio 1, 2025.

Round-trip from

$177
(American Airlines)

One-way from

$89
(United Airlines)

Popular in

July

Cheapest in

February

Average price

$506
From Des Moines to Louisville Intl
One-way flight from Des Moines to Louisville Intl
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Des Moines to Louisville

Cheapest flights from Des Moines to Louisville
Explore the most affordable flight options available from Des Moines to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 1, 2025.

This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/146:12 pmDSM - SDF
1 stop4h 56mAmerican Airlines
jue. 8/217:33 amSDF - DSM
1 stop5h 41mAmerican Airlines
Deal found 6/30$177
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/198:25 amDSM - SDF
2 stops9h 00mSouthwest
mié. 8/203:20 pmSDF - DSM
2 stops8h 00mSouthwest
Deal found 7/1$187
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/165:45 amDSM - SDF
1 stop7h 04mDelta
lun. 10/201:20 pmSDF - DSM
1 stop4h 53mDelta
Deal found 6/30$197
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/147:53 pmDSM - SDF
1 stop13h 15mMultiple Airlines
jue. 8/219:13 pmSDF - DSM
2 stops26h 29mMultiple Airlines
Deal found 6/30$249
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/283:38 pmDSM - SDF
1 stop5h 36mUnited Airlines
vie. 8/18:40 amSDF - DSM
1 stop7h 01mUnited Airlines
Deal found 6/30$317

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 1, 2025.
Use the filters below to find and compare flights from Des Moines to Louisville that are best for you.

Fly from

Des Moines

Fly to

Louisville

Route

Depart

Return

Price

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

jue. 8/14

6:12 pm-12:08 am

1 stop4h 56m

Louisville Intl

jue. 8/21

7:33 am-12:14 pm

1 stop5h 41m

$177

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

mar. 8/19

8:25 am-6:25 pm

2 stops9h 00m

Louisville Intl

mié. 8/20

3:20 pm-10:20 pm

2 stops8h 00m

$187

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

jue. 10/16

5:45 am-1:49 pm

1 stop7h 04m

Louisville Intl

lun. 10/20

1:20 pm-5:13 pm

1 stop4h 53m

$197

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

jue. 8/14

7:53 pm-10:08 am

1 stop13h 15m

Louisville Intl

jue. 8/21

9:13 pm-10:42 pm

2 stops26h 29m

$249

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

lun. 7/28

3:38 pm-10:14 pm

1 stop5h 36m

Louisville Intl

vie. 8/1

8:40 am-2:41 pm

1 stop7h 01m

$317

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

mar. 8/19

11:35 am-6:58 pm

1 stop6h 23m

$89

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

mar. 8/19

8:25 am-6:25 pm

2 stops9h 00m

$94

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

dom. 10/12

6:20 am-1:39 pm

1 stop6h 19m

$160

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

dom. 10/12

10:41 am-8:11 am

2 stops20h 30m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Des Moines to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Louisville

What is the cheapest month to book a flight from Des Moines to Louisville?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $299). Flying from Des Moines to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated julio 1, 2025.
Read through reviews of airlines operating flights from Des Moines to Louisville, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.2

Entertainment

7.6

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Boarding

8.2

Entertainment

7.6

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
8.0
Very good

Boarding

8.2

Entertainment

7.6

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Boarding

8.2

Entertainment

7.6

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Boarding

8.2

Entertainment

7.6

Food

7.0

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Des Moines to Louisville round-trip?

    American Airlines, at $177, was found to be the cheapest airline from Des Moines to Louisville.Alternate airlines to your destination round-trip include Southwest and Delta. American Airlines is priced at 55% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Louisville one-way?

    $89 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Southwest and Delta, with prices starting from $94 and $160, respectively.

  • Can I find deals for flights from Des Moines to Louisville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Louisville.

  • Can I find deals for business class flights from Des Moines to Louisville?

    Yes. Cheapflights offers flight deals from Des Moines to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Louisville (average of $299). Flying from Des Moines to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 3 airlines flying from Des Moines to Louisville

Discover the top 3 airlines that operate flights from Des Moines to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$336FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$264Average$376FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$306Average$432FlexibilityNo cancel feeOn-time69%

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