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Lexington

$194+ Cheap flights from Des Moines to Lexington (DSM - LEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LEX
Jul 9 — Jul 161
Thu 7/9
Thu 7/16
1 adult, Economy
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Cheap flight deals from Des Moines to Lexington

Cheapest flights from Des Moines to Lexington
Explore the most affordable flight options available from Des Moines to Lexington. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.

This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:00 am
DSM
-
LEX
1 stop5h 13m
American Airlines
Fri 7/106:53 pm
LEX
-
DSM
1 stop6h 08m
American Airlines
Deal found 6/5$309
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/44:52 pm
DSM
-
LEX
1 stop6h 12m
Delta
Fri 7/101:02 pm
LEX
-
DSM
1 stop5h 50m
Delta
Deal found 6/8$319
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:08 pm
DSM
-
LEX
1 stop4h 35m
American Airlines
Tue 9/15:00 pm
LEX
-
DSM
2 stops8h 20m
American Airlines
Deal found 6/8$324
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
DSM
-
LEX
2 stops10h 43m
American Airlines
Wed 9/211:15 am
LEX
-
DSM
2 stops9h 04m
American Airlines
Deal found 6/8$329
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:40 am
DSM
-
LEX
1 stop5h 31m
Delta
Sun 8/96:00 am
LEX
-
DSM
1 stop5h 43m
Delta
Deal found 6/7$364
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:35 pm
DSM
-
LEX
1 stop8h 03m
United Airlines
Wed 8/197:00 am
LEX
-
DSM
1 stop4h 26m
United Airlines
Deal found 6/4$389
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:08 pm
DSM
-
LEX
1 stop6h 43m
American Airlines
Tue 9/86:59 pm
LEX
-
DSM
1 stop6h 21m
American Airlines
Deal found 6/5$395
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:41 pm
DSM
-
LEX
1 stop7h 42m
American Airlines
Thu 7/305:35 am
LEX
-
DSM
1 stop3h 48m
American Airlines
Deal found 6/8$398

Find flight deals from Des Moines to Lexington

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Lexington (LEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

One-way from

$197
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$416
Provider with most accurate pricing for Des Moines-Lexington Blue Grass flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Lexington Blue Grass flights.
Search Deals
From Des Moines to Lexington Blue Grass
Search Deals
One-way flight from Des Moines to Lexington Blue Grass
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($159 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Lexington that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Des Moines to Lexington that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Sat 7/4

7:00 am-1:13 pm

1 stop5h 13m

Lexington Blue Grass

Fri 7/10

6:53 pm-12:01 am

1 stop6h 08m

$309

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Fri 8/28

10:23 am-5:21 pm

1 stop5h 58m

Lexington Blue Grass

Tue 9/1

10:52 am-4:48 pm

1 stop6h 56m

$319

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Fri 8/7

5:40 am-12:11 pm

1 stop5h 31m

Lexington Blue Grass

Sun 8/9

6:00 am-10:43 am

1 stop5h 43m

$364

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Sat 8/15

1:35 pm-10:38 pm

1 stop8h 03m

Lexington Blue Grass

Wed 8/19

7:00 am-10:26 am

1 stop4h 26m

$389
Quickest round-trip

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Thu 9/3

1:08 pm-8:51 pm

1 stop6h 43m

Lexington Blue Grass

Tue 9/8

6:34 am-10:00 am

1 stop4h 26m

$400

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Mon 7/13

5:41 am-12:17 pm

1 stop5h 36m

Lexington Blue Grass

Thu 7/16

10:51 am-5:12 pm

1 stop7h 21m

$487

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Fri 8/28

10:26 am-6:43 pm

2 stops7h 17m

Lexington Blue Grass

Tue 9/1

5:00 pm-12:20 am

2 stops8h 20m

$513
Cheapest one-way

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Tue 7/7

4:14 pm-11:25 am

1 stop18h 11m

$194

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Sat 7/25

4:59 pm-7:55 am

1 stop13h 56m

$197

Des MoinesLexington

DSM - LEX

DSMLEX

Des Moines

Tue 7/7

5:00 am-4:04 pm

2 stops10h 04m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Des Moines to Lexington

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Lexington in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Lexington flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Lexington flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Lexington flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Lexington flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Lexington flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Lexington

Have a flexible travel schedule? Discover the best time to fly to Lexington from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Lexington

How much does it cost to fly round-trip from Des Moines to Lexington?

Reviews of airlines servicing Lexington

Get insights into the airlines that provide service to Lexington. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lexington. Reviews last updated June 9, 2026.
See what other customers who have flown with United Airlines and American Airlines from Des Moines to Lexington have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,796 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,796 reviews
United Airlines
7.4
Good
9,796 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
American Airlines
7.1
Good
11,640 reviews
United Airlines
7.4
Good
9,796 reviews

Crew

8.1

Food

6.6

Comfort

7.3

Entertainment

7.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Lexington. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Lexington?

    Delta and United Airlines can get you from Des Moines to Lexington in just under 5h 58m. Your travel time can differ by up to 2h 05m. The distance between Des Moines and Lexington is about 537 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Lexington round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Des Moines to Lexington. An alternate airline flying to your destination would be United Airlines. You may be able to fly from Des Moines to Lexington for 48% less than the average price by searching for these airlines.

  • Can I find deals for flights from Des Moines to Lexington that include hotel bookings?

    Yes. In addition to deals on Des Moines to Lexington flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Lexington?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Lexington.

  • Can I find deals for business class flights from Des Moines to Lexington?

    Yes. Cheapflights offers flight deals from Des Moines to Lexington by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lexington?

Book flights to Lexington if you plan to visit one of these locations
Somerset
Richmond
Danville
Berea
Frankfort
Georgetown

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Top 2 airlines flying from Des Moines to Lexington

Discover the top 2 airlines that operate flights from Des Moines to Lexington. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$422FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$308Average$497FlexibilityNo cancel feeOn-time69%

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