$339+ Cheap flights from Lexington to Des Moines (LEX - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Lexington to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Lexington to Des Moines
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Cheapest flights from Lexington to Des MoinesExplore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:10 am -
1 stop6h 09m
Sat 11/286:45 pm -
1 stop4h 09m
Deal found 10/24![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop6h 48m
Tue 12/11:58 pm -
2 stops9h 00m
Deal found 10/25![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 44m
Sat 11/1411:00 am -
1 stop6h 53m
Deal found 10/25![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:33 am -
2 stops9h 23m
Sat 11/1411:09 am -
1 stop6h 34m
Deal found 10/25![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:25 am -
1 stop6h 07m
Sun 11/86:45 pm -
1 stop4h 09m
Deal found 10/22![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
1 stop6h 39m
Wed 12/93:20 pm -
1 stop6h 12m
Deal found 10/21![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:33 am -
2 stops9h 23m
Sun 11/87:06 am -
1 stop4h 42m
Deal found 10/22![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:10 pm -
1 stop5h 16m
Sat 11/287:24 pm -
1 stop14h 26m
Deal found 10/24![American Airlines logo]()
$523
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:19 pm -
1 stop13h 15m
Thu 11/1210:48 am -
1 stop28h 31m
Deal found 10/23![Allegiant Air logo]()
$525
Best flights from Lexington to Des MoinesDiscover carefully curated flight deals from Lexington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Lexington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:10 am -
1 stop6h 09m
Sat 11/286:45 pm -
1 stop4h 09m
Deal found 10/24![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop6h 48m
Tue 12/11:58 pm -
2 stops9h 00m
Deal found 10/25![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 44m
Sat 11/1411:00 am -
1 stop6h 53m
Deal found 10/25![Delta logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:19 pm -
1 stop13h 15m
Thu 11/1210:48 am -
1 stop28h 31m
Deal found 10/23![Allegiant Air logo]()
$525
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:10 am -
1 stop4h 22m
Tue 12/13:20 pm -
1 stop4h 05m
Deal found 10/25![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:33 am -
2 stops9h 23m
Sat 11/1411:09 am -
1 stop6h 34m
Deal found 10/25![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
1 stop6h 39m
Wed 12/93:20 pm -
1 stop6h 12m
Deal found 10/25![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:00 am -
2 stops9h 28m
Sat 11/287:24 pm -
1 stop14h 26m
Deal found 10/24![American Airlines logo]()
$737
Last-minute flights from Lexington to Des MoinesDiscover last-minute flight deals from Lexington to Des Moines. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Lexington to Des Moines. Data last updated October 26, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:25 am -
1 stop6h 07m
Sun 11/86:45 pm -
1 stop4h 09m
Deal found 10/22![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:33 am -
2 stops9h 23m
Sun 11/87:06 am -
1 stop4h 42m
Deal found 10/22![American Airlines logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:19 pm -
1 stop13h 15m
Thu 11/1210:48 am -
1 stop28h 31m
Deal found 10/23![Allegiant Air logo]()
$525
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/85:00 am -
1 stop6h 48m
Thu 11/129:25 am -
2 stops9h 16m
Deal found 10/23![American Airlines logo]()
$742
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 44m
Sat 11/1411:00 am -
1 stop6h 53m
Deal found 10/25![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:33 am -
2 stops9h 23m
Sat 11/1411:09 am -
1 stop6h 34m
Deal found 10/25![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:10 am -
1 stop6h 09m
Sat 11/286:45 pm -
1 stop4h 09m
Deal found 10/24![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:10 pm -
1 stop5h 16m
Sat 11/287:24 pm -
1 stop14h 26m
Deal found 10/24![American Airlines logo]()
$523
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop6h 48m
Tue 12/11:58 pm -
2 stops9h 00m
Deal found 10/25![American Airlines logo]()
$344
Find flight deals from Lexington to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (United Airlines) |
Popular in | August |
Cheapest in | January |
Average price | $428 |
Cheapflights Fare Finder
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Sat 11/21
7:10 am-12:19 pm
1 stop6h 09m
Des Moines
Sat 11/28
6:45 pm-11:54 pm
1 stop4h 09m
$339
Quickest round-trip
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Tue 11/24
7:10 am-10:32 am
1 stop4h 22m
Des Moines
Tue 12/1
3:20 pm-8:25 pm
1 stop4h 05m
$339
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Tue 11/24
5:00 am-10:48 am
1 stop6h 48m
Des Moines
Tue 12/1
1:58 pm-11:58 pm
2 stops9h 00m
$344
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Tue 11/10
6:00 am-10:44 am
1 stop5h 44m
Des Moines
Sat 11/14
11:00 am-6:53 pm
1 stop6h 53m
$369
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Tue 11/10
10:33 am-6:56 pm
2 stops9h 23m
Des Moines
Sat 11/14
11:09 am-6:43 pm
1 stop6h 34m
$374
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Sat 12/5
7:00 am-12:39 pm
1 stop6h 39m
Des Moines
Wed 12/9
3:20 pm-10:32 pm
1 stop6h 12m
$439
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Sun 11/8
9:19 pm-9:34 am
1 stop13h 15m
Des Moines
Thu 11/12
10:48 am-4:19 pm
1 stop28h 31m
$525
LexingtonDes Moines
LEX Lexington Blue Grass - DSM Des Moines
LEXDSM
Lexington Blue Grass
Sat 11/21
5:00 am-1:28 pm
2 stops9h 28m
Des Moines
Sat 11/28
7:24 pm-10:50 am
1 stop14h 26m
$737
Sorted by cheapest first
Compare providers for flights from Lexington to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Lexington to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
LEX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 26, 2026.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Overall
7.3
Comfort
7.3
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Entertainment
7.1
Overall
7.3
Comfort
7.3
Crew
8.1
Boarding
7.7
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Search flights from Lexington to Des Moines by cabin class
Find flights from Lexington to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Lexington and Des Moines flights
Browse other Lexington and Des Moines flight options. Last updated on October 26, 2026.
Other flights from Lexington
Browse through other flights departing from Lexington. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Lexington to Des Moines
Discover the top airline that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$246 | Average$399 | FlexibilityNo cancel fee | On-time69% |