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Des Moines

$259+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheap flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:00 am
LEX
-
DSM
1 stop6h 20m
United Airlines
Mon 9/73:20 pm
DSM
-
LEX
1 stop4h 08m
United Airlines
Deal found 7/23$319
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:00 pm
LEX
-
DSM
2 stops8h 20m
American Airlines
Mon 8/311:08 pm
DSM
-
LEX
1 stop6h 43m
American Airlines
Deal found 7/24$324
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:10 am
LEX
-
DSM
1 stop4h 55m
Delta
Sat 8/1512:30 pm
DSM
-
LEX
1 stop3h 51m
Delta
Deal found 7/27$349
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:00 pm
LEX
-
DSM
2 stops8h 20m
American Airlines
Sat 8/151:08 pm
DSM
-
LEX
1 stop4h 35m
American Airlines
Deal found 7/27$354
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 am
LEX
-
DSM
2 stops9h 30m
American Airlines
Mon 10/1211:22 am
DSM
-
LEX
1 stop7h 09m
American Airlines
Deal found 7/25$369
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:49 pm
LEX
-
DSM
1 stop4h 01m
United Airlines
Sat 10/316:45 pm
DSM
-
LEX
1 stop4h 04m
United Airlines
Deal found 7/26$399
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:00 pm
LEX
-
DSM
2 stops8h 20m
American Airlines
Tue 9/81:08 pm
DSM
-
LEX
1 stop4h 35m
American Airlines
Deal found 7/23$405
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:05 pm
LEX
-
DSM
1 stop27h 12m
Allegiant Air
Sun 8/96:27 pm
DSM
-
LEX
1 stop12h 46m
Allegiant Air
Deal found 7/23$427
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:10 pm
LEX
-
DSM
1 stop4h 59m
American Airlines
Sat 7/256:18 pm
DSM
-
LEX
1 stop4h 30m
American Airlines
Deal found 7/23$439
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:05 am
LEX
-
DSM
1 stop5h 19m
American Airlines
Fri 8/287:49 pm
DSM
-
LEX
1 stop14h 28m
American Airlines
Deal found 7/24$453

Find flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

One-way from

$259
(Kiwi.com)

Popular in

February

Cheapest in

January

Average price

$283
Provider with most accurate pricing for Lexington Blue Grass-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Des Moines flights.
Search Deals
From Lexington Blue Grass to Des Moines
Search Deals
One-way flight from Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 9/3

7:00 am-12:20 pm

1 stop6h 20m

Des Moines

Mon 9/7

3:20 pm-8:28 pm

1 stop4h 08m

$319

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 9/4

10:52 am-5:11 pm

1 stop7h 19m

Des Moines

Tue 9/8

4:11 pm-11:54 pm

1 stop6h 43m

$319

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 8/24

6:34 am-9:56 am

1 stop4h 22m

Des Moines

Mon 8/31

1:08 pm-6:43 pm

1 stop4h 35m

$319

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sat 10/10

7:10 am-10:42 am

1 stop4h 32m

Des Moines

Mon 10/12

6:54 pm-11:58 pm

1 stop4h 04m

$319

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 8/11

10:10 am-2:05 pm

1 stop4h 55m

Des Moines

Sat 8/15

12:30 pm-5:21 pm

1 stop3h 51m

$349

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 8/11

5:00 pm-12:20 am

2 stops8h 20m

Des Moines

Sat 8/15

1:08 pm-6:43 pm

1 stop4h 35m

$354
Quickest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 10/28

7:49 pm-10:50 pm

1 stop4h 01m

Des Moines

Sat 10/31

6:45 pm-11:49 pm

1 stop4h 04m

$399
Cheapest one-way

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sun 10/18

2:37 pm-9:34 am

1 stop19h 57m

$259

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sun 10/18

8:59 pm-9:53 pm

3 stops25h 54m

$358

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sun 10/18

5:00 am-1:30 pm

2 stops9h 30m

$363

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/25

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Lexington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 27, 2026.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,041 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this
United Airlines
7.4
Good
10,041 reviews
United Airlines
7.4
Good
10,041 reviews

Boarding

7.7

Crew

8.1

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
6.0
Good

ROHIT,Jun 2026

IND - EWR

It should not be delayed by 2 hours. I missed the important event due to this

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like American Airlines, United Airlines, and Delta fly from Lexington to Des Moines in about 4h 26m. The time it takes to get you to your destination can typically vary by up to 1h 54m. Airlines will cover a distance of 537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $248. United Airlines is 43% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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Top airline flying from Lexington to Des Moines

Discover the top airline that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$272FlexibilityNo cancel feeOn-time69%

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