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Des Moines

$259+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:06 am
LEX
-
DSM
1 stop4h 31m
Delta
Sat 5/2310:56 am
DSM
-
LEX
1 stop6h 43m
Delta
Deal found 4/27$329
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:00 am
LEX
-
DSM
2 stops8h 54m
American Airlines
Sat 5/231:30 pm
DSM
-
LEX
1 stop8h 12m
American Airlines
Deal found 4/27$334
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
LEX
-
DSM
2 stops9h 21m
American Airlines
Wed 7/295:00 am
DSM
-
LEX
1 stop4h 50m
American Airlines
Deal found 4/27$358
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:10 pm
LEX
-
DSM
1 stop5h 00m
American Airlines
Sun 6/71:37 pm
DSM
-
LEX
1 stop5h 03m
American Airlines
Deal found 4/27$359
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:00 am
LEX
-
DSM
1 stop4h 11m
United Airlines
Tue 9/13:24 pm
DSM
-
LEX
1 stop4h 03m
United Airlines
Deal found 4/27$389
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:51 pm
LEX
-
DSM
1 stop5h 53m
American Airlines
Sat 11/74:03 pm
DSM
-
LEX
1 stop6h 56m
American Airlines
Deal found 4/27$395
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:19 am
LEX
-
DSM
1 stop7h 36m
Delta
Sat 5/94:00 pm
DSM
-
LEX
1 stop6h 59m
Delta
Deal found 4/25$399
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
LEX
-
DSM
2 stops8h 46m
American Airlines
Sat 5/911:11 am
DSM
-
LEX
1 stop3h 46m
American Airlines
Deal found 4/25$404
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:44 pm
LEX
-
DSM
1 stop18h 51m
Allegiant Air
Fri 6/512:56 pm
DSM
-
LEX
2 stops18h 12m
Allegiant Air
Deal found 4/27$405

Find flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$329
(Delta)

One-way from

$259
(Delta)

Popular in

April

Cheapest in

January

Average price

$1,215
Provider with most accurate pricing for Lexington Blue Grass-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Des Moines flights.
Search Deals
From Lexington Blue Grass to Des Moines
Search Deals
One-way flight from Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($141 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 20% potential price decrease ($77 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 8/19

5:50 pm-8:45 pm

1 stop3h 55m

Des Moines

Sat 8/22

11:04 am-6:54 pm

1 stop6h 50m

$329
Quickest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 5/22

5:52 pm-8:36 pm

1 stop3h 44m

Des Moines

Sun 5/24

5:27 am-12:19 pm

1 stop5h 52m

$329

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 5/20

10:06 am-1:37 pm

1 stop4h 31m

Des Moines

Sat 5/23

10:56 am-6:39 pm

1 stop6h 43m

$329

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 8/19

4:54 pm-10:06 pm

1 stop6h 12m

Des Moines

Sat 8/22

3:41 pm-11:56 pm

2 stops7h 15m

$334

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 5/20

6:00 am-1:54 pm

2 stops8h 54m

Des Moines

Sat 5/23

5:00 am-4:05 pm

2 stops10h 05m

$339

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 6/5

4:35 pm-12:35 am

2 stops9h 00m

Des Moines

Sun 6/7

1:37 pm-7:40 pm

1 stop5h 03m

$365
Cheapest one-way
Quickest one-way

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 8/4

5:56 pm-10:29 pm

1 stop5h 33m

$259

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 5/13

7:02 am-1:37 pm

1 stop7h 35m

$324

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 8/4

5:01 pm-12:06 am

2 stops8h 05m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Compare providers for flights from Lexington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Des Moines

How much does it cost to fly round-trip from Lexington to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 28, 2026.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,672 reviews
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
American Airlines
7.1
Good
11,677 reviews
United Airlines
7.4
Good
9,672 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like Delta fly from Lexington to Des Moines in about 3h 55m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 537 mi.

  • What are the cheapest airlines flying from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 45% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny

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Top 2 airlines flying from Lexington to Des Moines

Discover the top 2 airlines that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$283FlexibilityNo cancel feeOn-time69%

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