$94+ Cheap flights from Louisville to Des Moines (SDF - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Nov 8 — Nov 151
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Des Moines
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Cheapest flights from Louisville to Des MoinesExplore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 9, 2026.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:05 am -
1 stop4h 37m
Wed 10/286:00 am -
1 stop6h 53m
Deal found 10/5![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:55 pm -
2 stops7h 05m
Wed 10/285:35 am -
1 stop3h 30m
Deal found 10/5![Southwest logo]()
$238
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 pm -
1 stop4h 25m
Sat 10/315:20 am -
1 stop4h 20m
Deal found 10/8![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:55 pm -
1 stop4h 05m
Sat 12/1212:45 pm -
1 stop4h 05m
Deal found 10/7![Southwest logo]()
$264
This KAYAK deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:59 pm -
1 stop5h 36m
Thu 11/196:52 pm -
1 stop4h 18m
Deal found 10/5![Delta logo]()
$274
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:50 am -
1 stop3h 35m
Thu 11/193:30 pm -
1 stop4h 05m
Deal found 10/6![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop3h 30m
Thu 11/196:00 am -
1 stop3h 30m
Deal found 10/6![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
1 stop5h 31m
Wed 11/111:27 pm -
1 stop7h 57m
Deal found 10/5![United Airlines logo]()
$323
Best flights from Louisville to Des MoinesDiscover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
Discover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 9, 2026.
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:05 am -
1 stop4h 37m
Wed 10/286:00 am -
1 stop6h 53m
Deal found 10/5![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:55 pm -
2 stops7h 05m
Wed 10/285:35 am -
2 stops9h 55m
Deal found 10/5![Southwest logo]()
$243
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
1 stop5h 31m
Wed 11/111:27 pm -
1 stop7h 57m
Deal found 10/5![United Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 pm -
1 stop4h 25m
Sat 10/315:20 am -
1 stop4h 20m
Deal found 10/8![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:55 pm -
1 stop4h 05m
Sat 12/1212:45 pm -
1 stop4h 05m
Deal found 10/7![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop3h 30m
Thu 11/196:00 am -
1 stop3h 30m
Deal found 10/6![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:38 pm -
1 stop4h 02m
Fri 10/236:54 pm -
1 stop4h 05m
Deal found 10/5![Delta logo]()
$489
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:20 am -
1 stop3h 50m
Mon 10/264:30 pm -
1 stop3h 40m
Deal found 10/7![Southwest logo]()
$401
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:20 am -
1 stop6h 55m
Thu 12/37:00 am -
2 stops12h 35m
Deal found 10/8![Southwest logo]()
$468
Last-minute flights from Louisville to Des MoinesDiscover last-minute flight deals from Louisville to Des Moines. Data last updated October 9, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Des Moines. Data last updated October 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:43 pm -
1 stop11h 42m
Mon 10/262:49 pm -
2 stops42h 22m
Deal found 10/7![Multiple Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:05 am -
1 stop4h 37m
Wed 10/286:00 am -
1 stop6h 53m
Deal found 10/5![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:55 pm -
2 stops7h 05m
Wed 10/285:35 am -
1 stop3h 30m
Deal found 10/5![Southwest logo]()
$238
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 pm -
1 stop4h 25m
Sat 10/315:20 am -
1 stop4h 20m
Deal found 10/8![Southwest logo]()
$258
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am -
1 stop5h 31m
Wed 11/111:27 pm -
1 stop7h 57m
Deal found 10/5![United Airlines logo]()
$323
This KAYAK deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:59 pm -
1 stop5h 36m
Thu 11/196:52 pm -
1 stop4h 18m
Deal found 10/5![Delta logo]()
$274
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:50 am -
1 stop3h 35m
Thu 11/193:30 pm -
1 stop4h 05m
Deal found 10/6![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop3h 30m
Thu 11/196:00 am -
1 stop3h 30m
Deal found 10/6![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:20 am -
1 stop6h 55m
Thu 12/33:30 pm -
1 stop4h 05m
Deal found 10/8![Southwest logo]()
$375
One-way flights from Louisville to Des MoinesSearch for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
Search for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 9, 2026.
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:35 pm -
1 stop4h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Southwest logo]()
$94
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:35 pm -
1 stop3h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$117
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:10 am -
1 stop6h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![United Airlines logo]()
$148
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:35 pm -
2 stops6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:32 pm -
1 stop18h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Allegiant Air logo]()
$277
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:05 am -
1 stop4h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:55 pm -
2 stops7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/9![Southwest logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:39 am -
3 stops57h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$329
Find flight deals from Louisville to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $94 (Southwest) |
Popular in | July |
Cheapest in | September |
Average price | $393 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Wed 11/25
8:35 pm-11:35 pm
1 stop4h 00m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$94
Quickest round-trip
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Tue 12/1
7:35 pm-10:05 pm
1 stop3h 30m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$117
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Fri 12/11
5:35 pm-11:00 pm
2 stops6h 25m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$153
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Tue 10/27
7:05 am-10:42 am
1 stop4h 37m
Des Moines
Wed 10/28
6:00 am-1:53 pm
1 stop6h 53m
$233
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Tue 10/27
3:55 pm-10:00 pm
2 stops7h 05m
Des Moines
Wed 10/28
5:35 am-4:30 pm
2 stops9h 55m
$243
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Fri 10/30
7:50 pm-11:15 pm
1 stop4h 25m
Des Moines
Sat 10/31
5:20 am-10:40 am
1 stop4h 20m
$258
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Fri 12/11
7:55 pm-11:00 pm
1 stop4h 05m
Des Moines
Sat 12/12
12:45 pm-5:50 pm
1 stop4h 05m
$264
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Wed 10/14
7:05 am-10:42 am
1 stop4h 37m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$305
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Tue 11/17
7:35 pm-10:05 pm
1 stop3h 30m
Des Moines
Thu 11/19
6:00 am-10:30 am
1 stop3h 30m
$309
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Sat 10/17
10:55 am-8:50 pm
2 stops10h 55m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$310
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Louisville to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.
SDF-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 9, 2026.
Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Oct 2026
JAC - ATL
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Oct 2026
JAC - ATL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Louisville to Des Moines
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Complete your trip
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 9, 2026.
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Find flights from Louisville to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Des Moines flights
Browse other Louisville and Des Moines flight options. Last updated on October 9, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on October 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Louisville to Des Moines
Discover the top airline that operate flights from Louisville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$233 | Average$346 | FlexibilityNo cancel fee | On-timeN/A |