$140+ Cheap flights from Louisville to Des Moines (SDF - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Des Moines
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Best
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One-way
Cheapest flights from Louisville to Des MoinesExplore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:55 pm -
1 stop3h 30m
Sat 9/55:30 am -
1 stop3h 40m
Deal found 8/9![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:18 pm -
1 stop6h 17m
Sat 9/1210:35 am -
1 stop5h 54m
Deal found 8/7![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:50 am -
2 stops12h 05m
Fri 10/304:30 pm -
1 stop3h 35m
Deal found 8/7![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:59 pm -
1 stop7h 05m
Wed 9/162:29 pm -
1 stop7h 04m
Deal found 8/11![American Airlines logo]()
$312
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm -
1 stop4h 38m
Mon 9/71:21 pm -
1 stop6h 15m
Deal found 8/8![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:15 pm -
2 stops8h 45m
Mon 9/75:40 am -
1 stop3h 45m
Deal found 8/8![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:50 am -
2 stops11h 25m
Wed 9/166:10 am -
1 stop4h 10m
Deal found 8/11![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:59 pm -
1 stop5h 38m
Mon 8/246:55 am -
1 stop4h 00m
Deal found 8/8![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:00 am -
1 stop6h 16m
Wed 8/266:00 am -
1 stop6h 11m
Deal found 8/7![United Airlines logo]()
$349
Best flights from Louisville to Des MoinesDiscover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:55 pm -
1 stop3h 30m
Sat 9/55:30 am -
1 stop3h 40m
Deal found 8/9![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:36 pm -
1 stop7h 13m
Fri 10/306:00 am -
1 stop6h 53m
Deal found 8/7![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/63:20 pm -
1 stop6h 12m
Thu 1/73:15 pm -
1 stop3h 59m
Deal found 8/11![United Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2611:50 am -
2 stops12h 05m
Fri 10/305:10 am -
2 stops11h 30m
Deal found 8/7![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:59 pm -
1 stop5h 38m
Mon 8/246:55 am -
1 stop4h 00m
Deal found 8/8![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:00 am -
1 stop6h 16m
Wed 8/266:00 am -
1 stop6h 11m
Deal found 8/7![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:15 am -
1 stop6h 16m
Mon 9/281:24 pm -
1 stop6h 07m
Deal found 8/8![United Airlines logo]()
$357
Last-minute flights from Louisville to Des MoinesDiscover last-minute flight deals from Louisville to Des Moines. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Des Moines. Data last updated August 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:59 pm -
1 stop5h 38m
Mon 8/246:55 am -
1 stop4h 00m
Deal found 8/8![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:00 am -
1 stop6h 16m
Wed 8/266:00 am -
1 stop6h 11m
Deal found 8/7![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:55 pm -
1 stop3h 30m
Sat 9/55:30 am -
1 stop3h 40m
Deal found 8/9![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:45 pm -
1 stop4h 38m
Mon 9/71:21 pm -
1 stop6h 15m
Deal found 8/8![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:15 pm -
2 stops8h 45m
Mon 9/75:40 am -
1 stop3h 45m
Deal found 8/8![Southwest logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:18 pm -
1 stop6h 17m
Sat 9/1210:35 am -
1 stop5h 54m
Deal found 8/7![American Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:59 pm -
1 stop7h 05m
Wed 9/162:29 pm -
1 stop7h 04m
Deal found 8/11![American Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:50 am -
2 stops11h 25m
Wed 9/166:10 am -
1 stop4h 10m
Deal found 8/11![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:15 am -
1 stop6h 16m
Mon 9/281:24 pm -
1 stop6h 07m
Deal found 8/8![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:55 pm -
1 stop5h 55m
Mon 9/285:40 am -
2 stops6h 25m
Deal found 8/8![Southwest logo]()
$362
One-way flights from Louisville to Des MoinesSearch for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 am -
1 stop4h 38m
Deal found 8/10![Delta logo]()
$140
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:15 pm -
2 stops8h 45m
Deal found 8/10![Southwest logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:42 pm -
3 stops39h 13m
Deal found 8/8![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:56 pm -
3 stops29h 58m
Deal found 8/10![Multiple Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:10 pm -
1 stop4h 05m
Deal found 8/7![Southwest logo]()
$341
Find flight deals from Louisville to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (Southwest) |
One-way from | $140 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Sat 8/29
4:55 pm-7:25 pm
1 stop3h 30m
Des Moines
Sat 9/5
5:30 am-10:10 am
1 stop3h 40m
$279
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Mon 10/26
2:36 pm-8:49 pm
1 stop7h 13m
Des Moines
Fri 10/30
6:00 am-1:53 pm
1 stop6h 53m
$289
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Wed 1/6
3:20 pm-8:32 pm
1 stop6h 12m
Des Moines
Thu 1/7
3:15 pm-8:14 pm
1 stop3h 59m
$303
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Mon 10/26
11:50 am-10:55 pm
2 stops12h 05m
Des Moines
Fri 10/30
5:10 am-5:40 pm
2 stops11h 30m
$336
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Sat 8/22
5:59 pm-10:37 pm
1 stop5h 38m
Des Moines
Mon 8/24
6:55 am-11:55 am
1 stop4h 00m
$348
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Sat 8/22
9:00 am-2:16 pm
1 stop6h 16m
Des Moines
Wed 8/26
6:00 am-1:11 pm
1 stop6h 11m
$349
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Sat 9/26
5:15 am-10:31 am
1 stop6h 16m
Des Moines
Mon 9/28
1:24 pm-8:31 pm
1 stop6h 07m
$357
Cheapest one-way
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Wed 8/26
7:05 am-10:43 am
1 stop4h 38m
$140
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Wed 8/26
1:15 pm-9:00 pm
2 stops8h 45m
$145
LouisvilleDes Moines
SDF Louisville Intl - DSM Des Moines
SDFDSM
Louisville Intl
Mon 9/28
9:42 pm-11:55 am
3 stops39h 13m
$230
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Louisville to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.
SDF-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 12, 2026.
Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Crew
8.5
Food
7.2
Overall
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
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Louisville and Des Moines flights
Browse other Louisville and Des Moines flight options. Last updated on August 12, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Louisville to Des Moines
Discover the top 2 airlines that operate flights from Louisville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$456 | FlexibilityNo cancel fee | On-time69% |