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Des Moines

$114+ Cheap flights from Louisville to Des Moines (SDF - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Aug 11 — Aug 181
Tue 8/11
Tue 8/18
1 adult, Economy
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Cheap flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.

This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:50 pm
SDF
-
DSM
1 stop6h 06m
United Airlines
Thu 8/66:50 pm
DSM
-
SDF
1 stop4h 09m
United Airlines
Deal found 7/9$227
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:30 am
SDF
-
DSM
2 stops7h 20m
Southwest
Wed 9/166:10 am
DSM
-
SDF
1 stop4h 10m
Southwest
Deal found 7/8$234
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:55 pm
SDF
-
DSM
1 stop4h 05m
United Airlines
Fri 8/143:20 pm
DSM
-
SDF
1 stop4h 16m
United Airlines
Deal found 7/9$257
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:00 am
SDF
-
DSM
1 stop3h 30m
Southwest
Fri 8/145:40 am
DSM
-
SDF
2 stops8h 50m
Southwest
Deal found 7/9$263
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:50 am
SDF
-
DSM
1 stop4h 28m
Delta
Wed 8/196:55 am
DSM
-
SDF
1 stop4h 00m
Delta
Deal found 7/12$273
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:25 am
SDF
-
DSM
1 stop4h 54m
United Airlines
Wed 10/281:05 pm
DSM
-
SDF
1 stop4h 56m
United Airlines
Deal found 7/7$297
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:55 pm
SDF
-
DSM
1 stop4h 01m
United Airlines
Wed 8/121:21 pm
DSM
-
SDF
1 stop6h 15m
United Airlines
Deal found 7/10$307
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:10 am
SDF
-
DSM
1 stop4h 21m
United Airlines
Wed 9/161:35 pm
DSM
-
SDF
1 stop8h 01m
United Airlines
Deal found 7/8$309
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:30 pm
SDF
-
DSM
1 stop5h 29m
Delta
Wed 8/196:55 am
DSM
-
SDF
1 stop4h 00m
Delta
Deal found 7/12$310
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am
SDF
-
DSM
2 stops7h 20m
Southwest
Fri 9/255:40 am
DSM
-
SDF
1 stop3h 45m
Southwest
Deal found 7/12$315
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:00 am
SDF
-
DSM
1 stop6h 16m
United Airlines
Sun 8/238:00 am
DSM
-
SDF
1 stop4h 11m
United Airlines
Deal found 7/10$317
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:45 am
SDF
-
DSM
2 stops13h 50m
Southwest
Wed 8/126:10 am
DSM
-
SDF
1 stop4h 10m
Southwest
Deal found 7/10$318

Find flight deals from Louisville to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$227
(United Airlines)

One-way from

$114
(Delta)
Provider with most accurate pricing for Louisville Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Des Moines flights.
Search Deals
From Louisville Intl to Des Moines
Search Deals
One-way flight from Louisville Intl to Des Moines
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Wed 8/5

5:50 pm-10:56 pm

1 stop6h 06m

Des Moines

Thu 8/6

6:50 pm-11:59 pm

1 stop4h 09m

$227

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 9/15

7:05 am-10:46 am

1 stop4h 41m

Des Moines

Wed 9/16

7:00 am-11:54 am

1 stop3h 54m

$227

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 9/15

5:30 am-11:50 am

2 stops7h 20m

Des Moines

Wed 9/16

6:10 am-11:20 am

1 stop4h 10m

$234

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 8/18

5:25 pm-8:39 pm

1 stop4h 14m

Des Moines

Thu 8/20

6:35 pm-12:34 am

1 stop4h 59m

$273

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 9/15

7:10 am-10:31 am

1 stop4h 21m

Des Moines

Wed 9/16

1:35 pm-10:36 pm

1 stop8h 01m

$309
Quickest round-trip

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sat 8/8

7:55 pm-11:00 pm

1 stop4h 05m

Des Moines

Fri 8/14

3:20 pm-8:36 pm

1 stop4h 16m

$310

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sun 8/16

6:50 am-10:18 am

1 stop4h 28m

Des Moines

Mon 8/17

6:00 am-1:51 pm

1 stop6h 51m

$310

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 8/21

9:00 am-2:16 pm

1 stop6h 16m

Des Moines

Sun 8/23

8:00 am-1:11 pm

1 stop4h 11m

$317

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 8/21

11:50 am-10:10 pm

2 stops11h 20m

Des Moines

Sun 8/23

5:40 am-10:25 am

1 stop3h 45m

$323

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Wed 8/5

6:45 pm-9:55 pm

1 stop4h 10m

Des Moines

Thu 8/6

5:40 am-3:30 pm

2 stops8h 50m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/9

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Louisville to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated July 12, 2026.
Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,458 reviews

Crew

8.5

Entertainment

7.8

Overall

7.8

Comfort

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,458 reviews
Delta
7.8
Good
8,458 reviews

Crew

8.5

Entertainment

7.8

Overall

7.8

Comfort

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
9,980 reviews
Delta
7.8
Good
8,458 reviews

Crew

8.5

Entertainment

7.8

Overall

7.8

Comfort

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,804 reviews
Delta
7.8
Good
8,458 reviews

Crew

8.5

Entertainment

7.8

Overall

7.8

Comfort

7.8

Food

7.2

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Des Moines?

    For as low as $227, United Airlines can have you in Des Moines from Louisville in 4h 41m. Airlines will cover a distance of 480 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Louisville to Des Moines round-trip?

    Flying on American Airlines is currently your cheapest option to Des Moines, with prices starting at $158. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $196 and $248, respectively.

  • Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.

  • Can I find deals for business class flights from Louisville to Des Moines?

    Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Louisville to Des Moines

Discover the top 3 airlines that operate flights from Louisville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$158Average$305FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$346FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$386FlexibilityNo cancel feeOn-time69%

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