$144+ Cheap flights from Des Moines (DSM) to Kentucky
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDF
Nov 26 — Dec 31
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to KentuckyExplore the most affordable flight options available from Des Moines to Kentucky. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
Explore the most affordable flight options available from Des Moines to Kentucky. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:52 pm -
1 stop4h 18m
Mon 11/165:40 pm -
1 stop4h 03m
Deal found 10/23![Delta logo]()
$245
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:53 pm -
1 stop4h 16m
Tue 12/88:05 am -
1 stop7h 08m
Deal found 10/27![Delta logo]()
$247
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:25 pm -
1 stop4h 10m
Tue 12/85:40 am -
2 stops6h 45m
Deal found 10/27![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:25 am -
1 stop3h 40m
Thu 12/36:50 am -
1 stop8h 25m
Deal found 10/25![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:20 pm -
1 stop4h 40m
Tue 1/197:00 am -
1 stop6h 17m
Deal found 10/27![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop3h 30m
Tue 1/193:55 pm -
2 stops6h 35m
Deal found 10/27![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:13 am -
1 stop7h 11m
Mon 11/163:14 pm -
1 stop6h 29m
Deal found 10/23![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:36 am -
1 stop6h 38m
Sun 11/226:42 am -
1 stop4h 37m
Deal found 10/26![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops12h 40m
Sun 11/227:55 pm -
1 stop4h 10m
Deal found 10/26![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:13 am -
1 stop7h 11m
Thu 12/310:13 am -
1 stop5h 00m
Deal found 10/27![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:38 am -
1 stop7h 00m
Sun 12/65:08 am -
1 stop4h 44m
Deal found 10/26![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 09m
Tue 11/107:10 am -
1 stop4h 22m
Deal found 10/22![United Airlines logo]()
$369
Best flights from Des Moines to KentuckyDiscover carefully curated flight deals from Des Moines to Kentucky that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
Discover carefully curated flight deals from Des Moines to Kentucky that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2026.
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:25 pm -
1 stop4h 10m
Tue 12/85:40 am -
2 stops6h 45m
Deal found 10/27![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:13 am -
1 stop7h 11m
Mon 11/163:14 pm -
1 stop6h 29m
Deal found 10/23![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop5h 57m
Sat 11/147:00 am -
1 stop8h 20m
Deal found 10/22![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:07 am -
1 stop7h 08m
Sat 11/710:33 am -
2 stops9h 20m
Deal found 10/23![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/311:04 am -
1 stop4h 47m
Tue 3/91:00 pm -
1 stop3h 57m
Deal found 10/25![Delta logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:05 am -
1 stop6h 32m
Sat 11/285:10 am -
1 stop6h 20m
Deal found 10/24![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/38:00 am -
1 stop3h 20m
Tue 3/95:45 am -
2 stops16h 45m
Deal found 10/25![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 09m
Tue 11/107:10 am -
1 stop4h 22m
Deal found 10/22![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:22 am -
1 stop5h 56m
Thu 11/127:05 am -
1 stop4h 39m
Deal found 10/23![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:20 am -
1 stop3h 55m
Thu 12/33:50 pm -
2 stops7h 15m
Deal found 10/27![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/316:15 am -
1 stop5h 45m
Fri 4/29:00 am -
1 stop6h 11m
Deal found 10/26![United Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 pm -
1 stop4h 09m
Sat 11/711:05 am -
1 stop4h 19m
Deal found 10/23![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:30 am -
1 stop5h 49m
Thu 12/176:00 am -
1 stop5h 53m
Deal found 10/26![Delta logo]()
$453
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:11 am -
2 stops9h 14m
Sat 11/285:16 am -
1 stop4h 39m
Deal found 10/27![American Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:45 pm -
1 stop4h 09m
Sat 11/286:15 pm -
1 stop4h 35m
Deal found 10/22![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:30 am -
1 stop5h 19m
Sat 11/286:00 am -
1 stop5h 46m
Deal found 10/24![Delta logo]()
$503
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:30 am -
1 stop5h 19m
Sun 11/295:59 pm -
1 stop5h 36m
Deal found 10/23![Delta logo]()
$553
This KAYAK deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:53 pm -
1 stop4h 11m
Fri 12/47:05 am -
1 stop4h 48m
Deal found 10/27![Delta logo]()
$556
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 pm -
1 stop4h 09m
Sat 11/285:25 am -
1 stop6h 05m
Deal found 10/25![United Airlines logo]()
$557
Last-minute flights from Des Moines to KentuckyDiscover last-minute flight deals from Des Moines to Kentucky. Data last updated October 27, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Kentucky. Data last updated October 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 09m
Tue 11/107:10 am -
1 stop4h 22m
Deal found 10/22![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:52 pm -
1 stop4h 18m
Mon 11/165:40 pm -
1 stop4h 03m
Deal found 10/23![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:25 am -
1 stop3h 40m
Mon 11/165:40 am -
2 stops6h 45m
Deal found 10/23![Southwest logo]()
$346
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
1 stop5h 57m
Sat 11/147:00 am -
1 stop8h 20m
Deal found 10/22![United Airlines logo]()
$335
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:23 am -
2 stops10h 20m
Sun 11/158:11 pm -
1 stop4h 46m
Deal found 10/27![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:13 am -
1 stop7h 11m
Mon 11/163:14 pm -
1 stop6h 29m
Deal found 10/23![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:36 am -
1 stop6h 38m
Sun 11/226:42 am -
1 stop4h 37m
Deal found 10/26![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
2 stops12h 40m
Sun 11/227:55 pm -
1 stop4h 10m
Deal found 10/26![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:05 am -
1 stop6h 32m
Sat 11/285:10 am -
1 stop6h 20m
Deal found 10/24![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:25 am -
1 stop3h 40m
Thu 12/36:50 am -
1 stop8h 25m
Deal found 10/25![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:00 am -
1 stop4h 35m
Sat 11/285:10 am -
1 stop6h 20m
Deal found 10/27![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:13 am -
1 stop7h 11m
Thu 12/310:13 am -
1 stop5h 00m
Deal found 10/27![Delta logo]()
$312
One-way flights from Des Moines to KentuckySearch for one-way flight options from Des Moines to Kentucky. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
Search for one-way flight options from Des Moines to Kentucky. Find affordable one-way fares based on user searches. Data last updated October 27, 2026.
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:53 pm -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Delta logo]()
$144
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
2 stops12h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/201:59 pm -
1 stop29h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Allegiant Air logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:55 am -
2 stops22h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$216
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/288:00 am -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:40 am -
3 stops28h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:00 am -
1 stop4h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![United Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:11 am -
2 stops11h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![American Airlines logo]()
$896
Find flight deals from Des Moines to Kentucky
Keep the following information in mind while searching for Des Moines to Kentucky flight deals. Data was last updated October 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $245 (Delta) |
One-way from | $144 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $328 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Kentucky that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
Use the filters below to find and compare flights from Des Moines to Kentucky that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Fri 12/4
6:53 pm-12:08 am
1 stop4h 15m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$144
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Fri 12/4
7:00 am-8:35 pm
2 stops12h 35m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Des MoinesLexington
DSM Des Moines - LEX Lexington Blue Grass
DSMLEX
Des Moines
Wed 1/20
1:59 pm-8:49 pm
1 stop29h 50m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$194
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Mon 12/7
3:25 pm-8:35 pm
1 stop4h 10m
Louisville Intl
Tue 12/8
5:40 am-11:25 am
2 stops6h 45m
$252
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Fri 11/13
6:13 am-2:24 pm
1 stop7h 11m
Louisville Intl
Mon 11/16
3:14 pm-8:43 pm
1 stop6h 29m
$278
Des MoinesLexington
DSM Des Moines - LEX Lexington Blue Grass
DSMLEX
Des Moines
Sat 11/28
8:00 am-1:15 pm
1 stop4h 15m
Lexington Blue Grass
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Fri 12/4
10:40 am-4:32 pm
3 stops28h 52m
Louisville Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$288
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Tue 11/10
3:01 pm-9:58 pm
1 stop5h 57m
Louisville Intl
Sat 11/14
7:00 am-2:20 pm
1 stop8h 20m
$335
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Wed 3/3
11:04 am-4:51 pm
1 stop4h 47m
Louisville Intl
Tue 3/9
1:00 pm-3:57 pm
1 stop3h 57m
$336
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Sat 11/21
6:05 am-1:37 pm
1 stop6h 32m
Louisville Intl
Sat 11/28
5:10 am-10:30 am
1 stop6h 20m
$336
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Kentucky
Have a flexible travel schedule? Discover the best time to fly to Kentucky from Des Moines with our price prediction graph.
DSM-SDF
DSM-LEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Kentucky
DSM-USKY
DSM-SDF
DSM-LEX
What is the cheapest month to book a flight from Des Moines to Kentucky?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Kentucky (average of $260). Flying from Des Moines to Kentucky in February is currently the most expensive (average of $685). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Kentucky?
Airfare is below average for this route at the moment.
Des Moines to Kentucky flights typically cost between $406 and $622 in November.The cheapest round-trip price found within the last 5 days was $245 on Delta (Nov 9-Nov 16).
Reviews of airlines servicing Kentucky
Get insights into the airlines that provide service to Kentucky. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Kentucky. Reviews last updated October 27, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to Kentucky by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Boarding
8.1
Entertainment
7.4
Comfort
8.0
Food
7.0
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Kentucky. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Kentucky
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Complete your trip
Complete your trip to Kentucky by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Kentucky by cabin class
Find flights from Des Moines to Kentucky, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Kentucky flights
Browse other Des Moines and Kentucky flight options. Last updated on October 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Kentucky flights
Consider these flights traveling from Des Moines to Kentucky.
Top 4 airlines flying from Des Moines to Kentucky
Discover the top 4 airlines that operate flights from Des Moines to Kentucky. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$346 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$260 | Average$452 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$504 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$446 | FlexibilityNo cancel fee | On-timeN/A |