$114+ Cheap flights from Des Moines (DSM) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MSY
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Louisiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Des Moines to LouisianaExplore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Des Moines to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Frontier deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Fri 9/1810:48 am -
1 stop8h 45m
Deal found 8/9![Frontier logo]()
$261
This CheapOair deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:29 am -
1 stop22h 24m
Mon 9/2110:48 am -
1 stop8h 45m
Deal found 8/8![Frontier logo]()
$268
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm -
1 stop6h 05m
Thu 9/175:00 am -
1 stop6h 25m
Deal found 8/10![Southwest logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm -
1 stop8h 22m
Sat 8/297:11 pm -
2 stops24h 43m
Deal found 8/8![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Fri 9/187:00 am -
2 stops15h 08m
Deal found 8/9![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Tue 9/153:17 pm -
2 stops41h 32m
Deal found 8/6![Multiple Airlines logo]()
$304
This Priceline deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:19 pm -
1 stop6h 48m
Fri 9/1110:48 am -
1 stop8h 45m
Deal found 8/7![Frontier logo]()
$306
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:11 pm -
1 stop5h 42m
Sat 9/126:07 am -
1 stop4h 39m
Deal found 8/5![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm -
2 stops50h 24m
Thu 9/179:00 pm -
1 stop22h 48m
Deal found 8/10![Multiple Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:10 pm -
1 stop5h 30m
Tue 12/298:30 am -
1 stop8h 30m
Deal found 8/9![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:24 am -
2 stops11h 09m
Sat 9/124:10 pm -
1 stop6h 20m
Deal found 8/5![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:55 am -
1 stop5h 19m
Sat 9/56:00 pm -
1 stop5h 16m
Deal found 8/7![American Airlines logo]()
$325
Best flights from Des Moines to LouisianaDiscover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Des Moines to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:11 pm -
1 stop5h 42m
Sat 9/126:07 am -
1 stop4h 39m
Deal found 8/5![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:15 am -
1 stop4h 58m
Sat 9/127:15 am -
2 stops9h 04m
Deal found 8/6![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops7h 45m
Wed 9/301:30 pm -
2 stops7h 35m
Deal found 8/6![Southwest logo]()
$375
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:15 am -
1 stop4h 58m
Sat 8/299:35 am -
1 stop4h 39m
Deal found 8/10![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:58 pm -
1 stop5h 41m
Mon 11/164:29 pm -
1 stop4h 44m
Deal found 8/5![Delta logo]()
$365
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/123:10 pm -
1 stop7h 15m
Mon 1/186:00 am -
1 stop12h 10m
Deal found 8/5![Southwest logo]()
$383
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:02 pm -
1 stop4h 58m
Tue 9/14:08 pm -
1 stop6h 22m
Deal found 8/6![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:25 am -
2 stops7h 45m
Mon 11/163:05 pm -
2 stops6h 55m
Deal found 8/5![Southwest logo]()
$388
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:40 am -
1 stop6h 02m
Thu 9/105:10 pm -
1 stop5h 16m
Deal found 8/7![Delta logo]()
$416
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:50 pm -
1 stop10h 25m
Sun 11/155:50 am -
1 stop7h 20m
Deal found 8/6![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop7h 20m
Tue 9/294:07 pm -
1 stop6h 08m
Deal found 8/8![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:00 am -
2 stops8h 20m
Sun 12/65:50 am -
1 stop7h 20m
Deal found 8/7![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/58:00 am -
1 stop4h 55m
Thu 1/710:35 am -
1 stop6h 58m
Deal found 8/8![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:34 pm -
1 stop7h 00m
Mon 9/285:15 pm -
1 stop5h 11m
Deal found 8/7![Delta logo]()
$472
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:10 pm -
1 stop5h 00m
Mon 10/125:50 am -
1 stop7h 30m
Deal found 8/5![Southwest logo]()
$414
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:33 am -
2 stops8h 30m
Sat 8/295:05 am -
2 stops7h 27m
Deal found 8/10![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/93:00 pm -
1 stop4h 38m
Tue 1/125:15 am -
1 stop9h 05m
Deal found 8/5![United Airlines logo]()
$467
Last-minute flights from Des Moines to LouisianaDiscover last-minute flight deals from Des Moines to Louisiana. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Louisiana. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:38 pm -
1 stop8h 22m
Sat 8/297:11 pm -
2 stops24h 43m
Deal found 8/8![Multiple Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:55 am -
1 stop5h 19m
Sat 9/56:00 pm -
1 stop5h 16m
Deal found 8/5![American Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am -
2 stops6h 45m
Sat 9/510:15 am -
2 stops10h 35m
Deal found 8/5![Southwest logo]()
$335
This Priceline deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:19 pm -
1 stop6h 48m
Fri 9/1110:48 am -
1 stop8h 45m
Deal found 8/7![Frontier logo]()
$306
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:11 pm -
1 stop5h 42m
Sat 9/126:07 am -
1 stop4h 39m
Deal found 8/5![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:24 am -
2 stops11h 09m
Sat 9/124:10 pm -
1 stop6h 20m
Deal found 8/5![United Airlines logo]()
$324
This Frontier deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Fri 9/1810:48 am -
1 stop8h 45m
Deal found 8/9![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm -
1 stop6h 05m
Thu 9/175:00 am -
1 stop6h 25m
Deal found 8/10![Southwest logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Fri 9/187:00 am -
2 stops15h 08m
Deal found 8/9![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop22h 24m
Tue 9/153:17 pm -
2 stops41h 32m
Deal found 8/6![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm -
2 stops50h 24m
Thu 9/179:00 pm -
1 stop22h 48m
Deal found 8/10![Multiple Airlines logo]()
$319
This CheapOair deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:29 am -
1 stop22h 24m
Mon 9/2110:48 am -
1 stop8h 45m
Deal found 8/8![Frontier logo]()
$268
One-way flights from Des Moines to LouisianaSearch for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Des Moines to Louisiana. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:04 pm -
1 stop28h 25m
Deal found 8/8![Multiple Airlines logo]()
$114
This Priceline deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:19 pm -
1 stop6h 32m
Deal found 8/9![Frontier logo]()
$129
This CheapOair deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:51 pm -
1 stop23h 49m
Deal found 8/6![Frontier logo]()
$137
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:50 pm -
2 stops6h 50m
Deal found 8/9![Southwest logo]()
$147
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:59 am -
1 stop4h 32m
Deal found 8/5![Delta logo]()
$163
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:40 pm -
2 stops7h 45m
Deal found 8/5![Southwest logo]()
$168
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:50 pm -
1 stop10h 25m
Deal found 8/6![Southwest logo]()
$188
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:34 pm -
1 stop5h 34m
Deal found 8/9![Delta logo]()
$196
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:40 pm -
2 stops7h 50m
Deal found 8/9![Southwest logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:05 pm -
2 stops22h 27m
Deal found 8/8![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm -
1 stop5h 00m
Deal found 8/8![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:43 am -
2 stops31h 24m
Deal found 8/8![Multiple Airlines logo]()
$210
Find flight deals from Des Moines to Louisiana
Keep the following information in mind while searching for Des Moines to Louisiana flight deals. Data was last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (Frontier) |
One-way from | $114 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Des Moines to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Wed 9/9
4:11 pm-9:53 pm
1 stop5h 42m
Baton Rouge Ryan
Sat 9/12
6:07 am-10:46 am
1 stop4h 39m
$319
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Wed 9/9
6:15 am-11:13 am
1 stop4h 58m
Baton Rouge Ryan
Sat 9/12
7:15 am-4:19 pm
2 stops9h 04m
$324
Quickest round-trip
Des MoinesBaton Rouge
DSM Des Moines - BTR Baton Rouge Ryan
DSMBTR
Des Moines
Tue 8/25
6:15 am-11:13 am
1 stop4h 58m
Baton Rouge Ryan
Sat 8/29
9:35 am-2:14 pm
1 stop4h 39m
$349
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Wed 11/11
2:58 pm-8:39 pm
1 stop5h 41m
New Orleans Louis Armstrong
Mon 11/16
4:29 pm-9:13 pm
1 stop4h 44m
$365
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Sat 9/26
12:10 pm-7:55 pm
2 stops7h 45m
New Orleans Louis Armstrong
Wed 9/30
1:30 pm-9:05 pm
2 stops7h 35m
$375
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Tue 1/12
3:10 pm-10:25 pm
1 stop7h 15m
New Orleans Louis Armstrong
Mon 1/18
6:00 am-6:10 pm
1 stop12h 10m
$383
Des MoinesAlexandria
DSM Des Moines - AEX Alexandria
DSMAEX
Des Moines
Sat 8/29
3:02 pm-8:00 pm
1 stop4h 58m
Alexandria
Tue 9/1
4:08 pm-10:30 pm
1 stop6h 22m
$388
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/12
5:25 am-1:10 pm
2 stops7h 45m
New Orleans Louis Armstrong
Mon 11/16
3:05 pm-10:00 pm
2 stops6h 55m
$388
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 11/12
1:50 pm-12:15 am
1 stop10h 25m
New Orleans Louis Armstrong
Sun 11/15
5:50 am-1:10 pm
1 stop7h 20m
$396
Des MoinesNew Orleans
DSM Des Moines - MSY New Orleans Louis Armstrong
DSMMSY
Des Moines
Thu 12/3
6:00 am-2:20 pm
2 stops8h 20m
New Orleans Louis Armstrong
Sun 12/6
5:50 am-1:10 pm
1 stop7h 20m
$396
Showing 1-10 of 29 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Des Moines with our price prediction graph.
DSM-BTR
DSM-MSY
DSM-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Louisiana
DSM-USLA
DSM-BTR
DSM-MSY
DSM-AEX
What is the cheapest month to book a flight from Des Moines to Louisiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Louisiana (average of $356). Flying from Des Moines to Louisiana in July is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Louisiana?
Airfare is below average for this route at the moment.
Des Moines to Louisiana flights typically cost between $380 and $694 in September.The cheapest round-trip price found within the last 5 days was $261 on Frontier (Sep 10-Sep 18).
How far ahead should I book a flight from Des Moines to Louisiana?
Booking 64 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Louisiana. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from Des Moines to Louisiana, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Louisiana
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Complete your trip
Complete your trip to Louisiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Louisiana by cabin class
Find flights from Des Moines to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Louisiana flights
Browse other Des Moines and Louisiana flight options. Last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Louisiana flights
Consider these flights traveling from Des Moines to Louisiana.
Top 4 airlines flying from Des Moines to Louisiana
Discover the top 4 airlines that operate flights from Des Moines to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$283 | Average$433 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$290 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$392 | FlexibilityNo cancel fee | On-time69% |