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Des Moines

$125+ Cheap flights from Louisiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Aug 9 — Aug 161
Sun 8/9
Sun 8/16
1 adult, Economy
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Cheap flight deals from Louisiana to Des Moines

Cheapest flights from Louisiana to Des Moines
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.

This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:05 am
MSY
-
DSM
1 stop5h 00m
Delta
Mon 8/106:35 pm
DSM
-
MSY
1 stop5h 03m
Delta
Deal found 7/7$249
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:15 am
MSY
-
DSM
1 stop4h 15m
Southwest
Sat 8/225:30 am
DSM
-
MSY
2 stops8h 50m
Southwest
Deal found 7/8$254
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:30 pm
MSY
-
DSM
2 stops8h 25m
Southwest
Tue 8/1112:30 pm
DSM
-
MSY
1 stop9h 20m
Southwest
Deal found 7/7$268
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:12 am
MSY
-
DSM
1 stop5h 31m
Delta
Mon 8/106:35 pm
DSM
-
MSY
1 stop5h 03m
Delta
Deal found 7/7$282
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:50 am
MSY
-
DSM
1 stop9h 20m
Southwest
Fri 8/213:50 pm
DSM
-
MSY
1 stop6h 00m
Southwest
Deal found 7/7$292
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:05 pm
MSY
-
DSM
2 stops19h 51m
Multiple Airlines
Sun 9/139:56 pm
DSM
-
MSY
1 stop14h 31m
Multiple Airlines
Deal found 7/8$295
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:02 pm
MSY
-
DSM
2 stops26h 55m
Multiple Airlines
Sun 9/139:56 pm
DSM
-
MSY
1 stop14h 31m
Multiple Airlines
Deal found 7/8$306
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:14 pm
BTR
-
DSM
1 stop5h 11m
American Airlines
Thu 8/204:13 pm
DSM
-
BTR
1 stop6h 42m
American Airlines
Deal found 7/8$309
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:14 pm
MSY
-
DSM
2 stops23h 20m
Frontier
Mon 8/102:19 pm
DSM
-
MSY
1 stop6h 44m
Frontier
Deal found 7/9$310
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:26 am
BTR
-
DSM
2 stops10h 13m
Delta
Tue 8/182:54 pm
DSM
-
BTR
1 stop7h 07m
Delta
Deal found 7/6$314
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:27 pm
BTR
-
DSM
1 stop4h 28m
American Airlines
Sun 8/236:34 am
DSM
-
BTR
1 stop7h 23m
American Airlines
Deal found 7/9$324
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:00 am
MSY
-
DSM
1 stop7h 16m
United Airlines
Sun 8/166:15 am
DSM
-
MSY
1 stop4h 51m
United Airlines
Deal found 7/8$328

Find flight deals from Louisiana to Des Moines

Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated July 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$125
(Delta)

Popular in

April

Cheapest in

October

Average price

$406
Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.
Search Deals
From Louisiana to Des Moines
Search Deals
One-way flight from Louisiana to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 8/7

6:50 pm-12:20 am

1 stop5h 30m

Des Moines

Mon 8/10

6:22 pm-10:59 pm

1 stop4h 37m

$282

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 8/7

5:12 am-10:43 am

1 stop5h 31m

Des Moines

Mon 8/10

6:35 pm-11:38 pm

1 stop5h 03m

$282

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Sat 8/15

6:50 am-4:10 pm

1 stop9h 20m

Des Moines

Fri 8/21

3:50 pm-9:50 pm

1 stop6h 00m

$292

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Thu 8/20

2:27 pm-6:55 pm

1 stop4h 28m

Des Moines

Sun 8/23

6:34 am-1:57 pm

1 stop7h 23m

$324

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Tue 9/29

10:31 am-5:48 pm

1 stop7h 17m

Des Moines

Wed 9/30

1:27 pm-9:44 pm

1 stop8h 17m

$329

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Tue 7/28

2:12 pm-6:33 pm

1 stop4h 21m

Des Moines

Mon 8/3

4:48 pm-10:57 pm

1 stop6h 09m

$388

Baton RougeDes Moines

BTR - DSM

BTRDSM

Baton Rouge Ryan

Sat 8/29

9:35 am-2:14 pm

1 stop4h 39m

Des Moines

Tue 9/1

3:02 pm-9:28 pm

1 stop6h 26m

$389

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Sat 8/29

7:30 am-2:14 pm

1 stop6h 44m

Des Moines

Wed 9/2

1:35 pm-9:36 pm

2 stops8h 01m

$394

Lake CharlesDes Moines

LCH - DSM

LCHDSM

Lake Charles

Wed 1/6

4:15 pm-10:30 pm

1 stop6h 15m

Des Moines

Sat 1/9

5:00 am-3:22 pm

2 stops10h 22m

$394

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

Fri 8/14

7:00 am-2:16 pm

1 stop7h 16m

Des Moines

Mon 8/17

3:20 pm-10:45 pm

2 stops7h 25m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/8

Showing 1-10 of 22 resultsSorted by cheapest first
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Best time to book a flight from Louisiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Des Moines

What is the cheapest month to book a flight from Louisiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $118). Flying from Louisiana to Des Moines in January is currently the most expensive (average of $576). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Louisiana to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Louisiana?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Louisiana to Des Moines.

  • How long is the flight from Louisiana to Des Moines?

    A quick flight from Louisiana to Des Moines can take about 5h 30m. Delta provides one of the quickest options available for as low as $282. Louisiana and Des Moines are separated by a distance of 820 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Louisiana to Des Moines one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $145. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Louisiana to Des Moines for a low price.

  • What are the most popular routes from Louisiana to Des Moines?

    While some choose either Baton Rouge Ryan - Des Moines or Lake Charles - Des Moines, New Orleans Louis Armstrong - Des Moines is the most popular route from Louisiana to Des Moines.

  • Can I find deals for flights from Louisiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Des Moines.

  • Can I find deals for business class flights from Louisiana to Des Moines?

    Yes. Cheapflights offers flight deals from Louisiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $118). Flying from Louisiana to Des Moines in January is currently the most expensive (average of $576). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for Louisiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Des Moines

Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$244Average$407FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$272Average$381FlexibilityNo cancel feeOn-time69%
DeltaCheapest$290Average$517FlexibilityNo cancel feeOn-timeN/A

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