$149+ Cheap flights from Louisiana to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Find cheap flights from Louisiana to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisiana to Des Moines
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Best
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One-way
Cheapest flights from Louisiana to Des MoinesExplore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This Frontier deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:48 am -
1 stop8h 45m
Thu 9/1711:29 am -
1 stop22h 24m
Deal found 8/21![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am -
2 stops15h 08m
Thu 9/1711:29 am -
1 stop22h 24m
Deal found 8/21![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:11 pm -
1 stop5h 01m
Mon 10/54:12 pm -
1 stop6h 44m
Deal found 8/20![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:31 am -
1 stop7h 17m
Tue 10/206:00 am -
1 stop5h 12m
Deal found 8/24![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:25 pm -
2 stops8h 30m
Tue 10/207:05 am -
2 stops9h 00m
Deal found 8/24![Southwest logo]()
$335
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:25 am -
1 stop8h 35m
Tue 12/297:10 pm -
1 stop5h 30m
Deal found 8/22![Southwest logo]()
$345
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am -
1 stop7h 10m
Sat 9/265:57 pm -
1 stop5h 41m
Deal found 8/23![American Airlines logo]()
$358
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:23 pm -
1 stop16h 11m
Thu 9/1011:29 am -
1 stop22h 24m
Deal found 8/22![Frontier logo]()
$365
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop7h 54m
Sun 9/275:56 pm -
1 stop5h 42m
Deal found 8/21![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:45 pm -
1 stop6h 45m
Sat 9/263:11 pm -
2 stops7h 48m
Deal found 8/23![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:56 pm -
1 stop5h 37m
Sun 11/15:39 am -
1 stop6h 02m
Deal found 8/24![Delta logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:10 pm -
1 stop6h 20m
Wed 9/166:15 am -
1 stop4h 58m
Deal found 8/19![United Airlines logo]()
$399
Best flights from Louisiana to Des MoinesDiscover carefully curated flight deals from Louisiana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from Louisiana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:25 am -
1 stop8h 35m
Tue 12/297:10 pm -
1 stop5h 30m
Deal found 8/22![Southwest logo]()
$345
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:45 pm -
1 stop6h 45m
Sat 9/263:11 pm -
2 stops7h 48m
Deal found 8/23![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:56 pm -
1 stop5h 37m
Sun 11/15:39 am -
1 stop6h 02m
Deal found 8/24![Delta logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 pm -
1 stop22h 48m
Sun 9/279:56 pm -
2 stops18h 35m
Deal found 8/21![Multiple Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3011:52 am -
1 stop7h 17m
Sat 1/29:53 am -
2 stops9h 04m
Deal found 8/19![American Airlines logo]()
$472
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:10 pm -
1 stop6h 20m
Wed 9/166:15 am -
1 stop4h 58m
Deal found 8/20![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am -
2 stops8h 15m
Sat 9/2612:10 pm -
2 stops7h 45m
Deal found 8/23![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:15 am -
2 stops8h 52m
Wed 11/41:27 pm -
2 stops8h 13m
Deal found 8/23![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:16 am -
2 stops10h 50m
Mon 1/45:15 pm -
1 stop4h 46m
Deal found 8/24![Delta logo]()
$476
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:11 pm -
1 stop5h 01m
Mon 10/52:01 pm -
2 stops8h 55m
Deal found 8/20![American Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:07 pm -
2 stops9h 48m
Sun 11/18:00 am -
1 stop5h 19m
Deal found 8/21![United Airlines logo]()
$476
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:05 pm -
1 stop5h 54m
Wed 12/306:00 am -
1 stop5h 07m
Deal found 8/20![United Airlines logo]()
$497
Last-minute flights from Louisiana to Des MoinesDiscover last-minute flight deals from Louisiana to Des Moines. Data last updated August 24, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Des Moines. Data last updated August 24, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:23 pm -
1 stop16h 11m
Thu 9/1011:29 am -
1 stop22h 24m
Deal found 8/22![Frontier logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:05 pm -
1 stop15h 05m
Thu 9/101:58 pm -
2 stops29h 09m
Deal found 8/22![Multiple Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/104:00 pm -
1 stop7h 33m
Mon 9/143:02 pm -
1 stop6h 55m
Deal found 8/20![United Airlines logo]()
$478
This Frontier deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:48 am -
1 stop8h 45m
Thu 9/1711:29 am -
1 stop22h 24m
Deal found 8/21![Frontier logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am -
2 stops15h 08m
Thu 9/1711:29 am -
1 stop22h 24m
Deal found 8/21![Multiple Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:00 am -
1 stop7h 10m
Sat 9/265:57 pm -
1 stop5h 41m
Deal found 8/23![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:45 pm -
1 stop6h 45m
Sat 9/263:11 pm -
2 stops7h 48m
Deal found 8/23![United Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am -
2 stops8h 15m
Thu 9/173:50 pm -
2 stops6h 55m
Deal found 8/21![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:30 am -
2 stops8h 15m
Sat 9/2612:10 pm -
2 stops7h 45m
Deal found 8/23![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:10 pm -
1 stop6h 20m
Wed 9/166:15 am -
1 stop4h 58m
Deal found 8/20![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:05 am -
1 stop7h 54m
Sun 9/275:56 pm -
1 stop5h 42m
Deal found 8/21![American Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:00 pm -
1 stop22h 48m
Sun 9/279:56 pm -
2 stops18h 35m
Deal found 8/21![Multiple Airlines logo]()
$465
One-way flights from Louisiana to Des MoinesSearch for one-way flight options from Louisiana to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from Louisiana to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:26 pm -
3 stops42h 28m
Deal found 8/23![Multiple Airlines logo]()
$149
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:02 pm -
1 stop4h 31m
Deal found 8/20![Delta logo]()
$163
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:00 am -
1 stop7h 15m
Deal found 8/24![United Airlines logo]()
$203
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:05 am -
1 stop6h 25m
Deal found 8/23![Southwest logo]()
$209
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am -
1 stop7h 20m
Deal found 8/20![United Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:50 am -
2 stops7h 25m
Deal found 8/20![Southwest logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:15 am -
3 stops35h 28m
Deal found 8/23![Multiple Airlines logo]()
$324
Find flight deals from Louisiana to Des Moines
Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated August 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $262 (Frontier) |
One-way from | $149 (Kiwi.com) |
Popular in | April |
Cheapest in | October |
Average price | $491 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Wed 12/23
8:25 am-5:00 pm
1 stop8h 35m
Des Moines
Tue 12/29
7:10 pm-12:40 am
1 stop5h 30m
$345
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 9/11
3:45 pm-10:30 pm
1 stop6h 45m
Des Moines
Sat 9/26
3:11 pm-10:59 pm
2 stops7h 48m
$381
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 10/30
4:56 pm-10:33 pm
1 stop5h 37m
Des Moines
Sun 11/1
5:39 am-11:41 am
1 stop6h 02m
$391
Baton RougeDes Moines
BTR Baton Rouge Ryan - DSM Des Moines
BTRDSM
Baton Rouge Ryan
Sat 9/12
4:10 pm-10:30 pm
1 stop6h 20m
Des Moines
Wed 9/16
6:15 am-11:13 am
1 stop4h 58m
$399
Lake CharlesDes Moines
LCH Lake Charles - DSM Des Moines
LCHDSM
Lake Charles
Sat 10/31
7:15 am-4:07 pm
2 stops8h 52m
Des Moines
Wed 11/4
1:27 pm-9:40 pm
2 stops8h 13m
$409
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 9/11
5:30 am-1:45 pm
2 stops8h 15m
Des Moines
Sat 9/26
12:10 pm-7:55 pm
2 stops7h 45m
$442
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Thu 9/24
9:00 pm-7:48 pm
1 stop22h 48m
Des Moines
Sun 9/27
9:56 pm-4:31 pm
2 stops18h 35m
$465
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Wed 12/30
11:52 am-7:09 pm
1 stop7h 17m
Des Moines
Sat 1/2
9:53 am-6:57 pm
2 stops9h 04m
$472
Baton RougeDes Moines
BTR Baton Rouge Ryan - DSM Des Moines
BTRDSM
Baton Rouge Ryan
Fri 1/1
6:16 am-5:06 pm
2 stops10h 50m
Des Moines
Mon 1/4
5:15 pm-10:01 pm
1 stop4h 46m
$476
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 10/30
12:07 pm-9:55 pm
2 stops9h 48m
Des Moines
Sun 11/1
8:00 am-1:19 pm
1 stop5h 19m
$476
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
MSY-DSM
BTR-DSM
LCH-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Des Moines
USLA-DSM
MSY-DSM
BTR-DSM
LCH-DSM
What is the cheapest month to book a flight from Louisiana to Des Moines?
Currently, October is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $272). Flying from Louisiana to Des Moines in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisiana to Des Moines?
Airfare is below average for this route at the moment.
Louisiana to Des Moines flights typically cost between $344 and $556 in September.The cheapest round-trip price found within the last 5 days was $262 on Frontier (Sep 11-Sep 17).
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
Browse thousands of different options on Cheapflights for your next trip
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 24, 2026.
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Find flights from Louisiana to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisiana and Des Moines flights
Browse other Louisiana and Des Moines flight options. Last updated on August 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Des Moines flights
Consider these flights traveling from Louisiana to Des Moines.
Top 3 airlines flying from Louisiana to Des Moines
Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$506 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$414 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$386 | FlexibilityNo cancel fee | On-time69% |