$133+ Cheap flights from Louisiana to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — DSM
Nov 15 — Nov 221
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Louisiana to Des MoinesExplore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2026.
Explore the most affordable flight options available from Louisiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2026.
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:05 pm -
1 stop5h 25m
Wed 12/307:10 pm -
1 stop5h 30m
Deal found 10/13![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:23 pm -
1 stop5h 42m
Mon 11/163:31 pm -
1 stop7h 23m
Deal found 10/15![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:02 am -
1 stop8h 07m
Sun 11/155:30 am -
1 stop6h 31m
Deal found 10/11![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:50 am -
1 stop7h 20m
Wed 12/93:30 pm -
1 stop7h 25m
Deal found 10/14![Southwest logo]()
$361
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:03 pm -
1 stop6h 27m
Mon 11/163:01 pm -
1 stop4h 30m
Deal found 10/11![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop5h 41m
Sun 11/16:00 am -
1 stop4h 31m
Deal found 10/12![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:09 pm -
1 stop6h 21m
Mon 11/161:27 pm -
2 stops9h 32m
Deal found 10/11![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:33 pm -
1 stop4h 40m
Wed 12/307:43 pm -
1 stop4h 16m
Deal found 10/11![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 am -
1 stop7h 05m
Sat 10/311:27 pm -
2 stops8h 13m
Deal found 10/12![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:33 pm -
1 stop5h 54m
Sun 11/225:23 am -
1 stop6h 20m
Deal found 10/12![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:30 am -
1 stop5h 14m
Sun 11/226:52 pm -
1 stop5h 07m
Deal found 10/15![Delta logo]()
$406
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:45 am -
1 stop7h 35m
Mon 10/261:27 pm -
1 stop7h 34m
Deal found 10/12![United Airlines logo]()
$419
Best flights from Louisiana to Des MoinesDiscover carefully curated flight deals from Louisiana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2026.
Discover carefully curated flight deals from Louisiana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2026.
This Southwest deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:05 pm -
1 stop5h 25m
Wed 12/307:10 pm -
1 stop5h 30m
Deal found 10/13![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:23 pm -
1 stop5h 42m
Mon 11/163:31 pm -
1 stop7h 23m
Deal found 10/15![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/54:09 pm -
1 stop6h 21m
Mon 2/88:00 am -
1 stop5h 25m
Deal found 10/11![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:02 am -
1 stop8h 07m
Sun 11/155:30 am -
1 stop6h 31m
Deal found 10/11![Delta logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:00 am -
2 stops15h 08m
Sun 11/17:45 am -
1 stop21h 15m
Deal found 10/12![Multiple Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am -
2 stops7h 10m
Wed 12/93:30 pm -
1 stop7h 25m
Deal found 10/14![Southwest logo]()
$366
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:03 pm -
1 stop6h 27m
Mon 11/163:01 pm -
1 stop4h 30m
Deal found 10/11![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:30 am -
1 stop5h 14m
Sun 11/226:52 pm -
1 stop5h 07m
Deal found 10/15![Delta logo]()
$406
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:09 pm -
1 stop6h 21m
Mon 11/161:27 pm -
2 stops9h 32m
Deal found 10/11![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:06 pm -
1 stop5h 01m
Sat 10/314:12 pm -
1 stop6h 34m
Deal found 10/12![American Airlines logo]()
$455
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:15 am -
1 stop5h 34m
Sat 1/26:43 pm -
1 stop4h 52m
Deal found 10/11![Delta logo]()
$428
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:30 am -
1 stop4h 50m
Wed 11/188:00 am -
1 stop7h 38m
Deal found 10/15![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:30 pm -
2 stops8h 50m
Sun 11/15:25 am -
2 stops7h 45m
Deal found 10/12![Southwest logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:43 pm -
1 stop4h 15m
Fri 1/156:14 pm -
1 stop4h 43m
Deal found 10/12![American Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:59 pm -
1 stop6h 30m
Sat 1/163:00 pm -
1 stop6h 46m
Deal found 10/12![United Airlines logo]()
$450
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:25 pm -
2 stops8h 50m
Fri 10/304:30 pm -
2 stops7h 25m
Deal found 10/11![Southwest logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:44 pm -
1 stop4h 21m
Mon 11/161:58 pm -
2 stops8h 52m
Deal found 10/11![American Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:15 am -
2 stops8h 52m
Tue 11/38:00 am -
1 stop5h 55m
Deal found 10/11![United Airlines logo]()
$459
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:09 pm -
1 stop5h 24m
Sun 11/15:39 am -
1 stop7h 29m
Deal found 10/12![Delta logo]()
$603
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2010:10 am -
1 stop5h 57m
Sun 11/221:27 pm -
1 stop8h 05m
Deal found 10/14![United Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:45 pm -
1 stop4h 22m
Sun 11/13:31 pm -
1 stop4h 50m
Deal found 10/12![American Airlines logo]()
$612
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/262:41 pm -
1 stop5h 55m
Fri 10/306:45 pm -
1 stop5h 08m
Deal found 10/11![United Airlines logo]()
$517
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop7h 26m
Sat 11/286:45 pm -
2 stops22h 34m
Deal found 10/14![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop7h 26m
Sun 11/16:45 pm -
2 stops26h 46m
Deal found 10/13![United Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:42 am -
1 stop7h 25m
Fri 10/306:45 pm -
2 stops24h 46m
Deal found 10/11![United Airlines logo]()
$698
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:09 pm -
1 stop6h 21m
Fri 11/206:45 pm -
2 stops20h 47m
Deal found 10/14![United Airlines logo]()
$752
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:30 pm -
2 stops8h 29m
Sun 11/299:00 pm -
2 stops20h 24m
Deal found 10/12![United Airlines logo]()
$753
Last-minute flights from Louisiana to Des MoinesDiscover last-minute flight deals from Louisiana to Des Moines. Data last updated October 16, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Des Moines. Data last updated October 16, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:45 am -
1 stop7h 35m
Mon 10/261:27 pm -
1 stop7h 34m
Deal found 10/12![United Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 am -
1 stop7h 05m
Sat 10/311:27 pm -
2 stops8h 13m
Deal found 10/12![United Airlines logo]()
$394
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 pm -
1 stop26h 20m
Sun 11/18:00 am -
2 stops31h 47m
Deal found 10/12![Multiple Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:26 pm -
1 stop5h 41m
Sun 11/16:00 am -
1 stop4h 31m
Deal found 10/12![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:00 am -
2 stops15h 08m
Sun 11/17:45 am -
1 stop21h 15m
Deal found 10/12![Multiple Airlines logo]()
$441
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:02 am -
1 stop8h 07m
Sun 11/155:30 am -
1 stop6h 31m
Deal found 10/11![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:03 pm -
1 stop6h 27m
Mon 11/163:01 pm -
1 stop4h 30m
Deal found 10/11![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:23 pm -
1 stop5h 42m
Mon 11/163:31 pm -
1 stop7h 23m
Deal found 10/15![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:09 pm -
1 stop6h 21m
Mon 11/161:27 pm -
2 stops9h 32m
Deal found 10/11![United Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:30 am -
1 stop4h 50m
Wed 11/188:00 am -
1 stop5h 26m
Deal found 10/12![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:33 pm -
1 stop5h 54m
Sun 11/225:23 am -
1 stop6h 20m
Deal found 10/12![American Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:30 am -
1 stop5h 14m
Sun 11/226:52 pm -
1 stop5h 07m
Deal found 10/15![Delta logo]()
$406
One-way flights from Louisiana to Des MoinesSearch for one-way flight options from Louisiana to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 16, 2026.
Search for one-way flight options from Louisiana to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 16, 2026.
This Frontier deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:58 am -
1 stop8h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Frontier logo]()
$133
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:40 am -
1 stop6h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Delta logo]()
$163
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:00 pm -
2 stops6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Southwest logo]()
$168
This Southwest deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/175:05 am -
1 stop6h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Southwest logo]()
$199
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:17 pm -
1 stop5h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 pm -
1 stop25h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$230
This Frontier deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1710:13 am -
2 stops9h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Frontier logo]()
$245
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:00 am -
1 stop7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:07 am -
2 stops10h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Delta logo]()
$289
Find flight deals from Louisiana to Des Moines
Keep the following information in mind while searching for Louisiana to Des Moines flight deals. Data was last updated October 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $325 (Southwest) |
One-way from | $133 (Frontier) |
Popular in | April |
Cheapest in | March |
Average price | $483 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 16, 2026.
Use the filters below to find and compare flights from Louisiana to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 12/18
7:40 am-2:13 pm
1 stop6h 33m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$163
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 12/18
5:00 pm-11:30 pm
2 stops6h 30m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Thu 12/17
2:10 pm-11:17 pm
2 stops9h 07m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Fri 12/11
1:35 pm-11:00 pm
2 stops9h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$168
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Sun 1/17
5:05 am-11:30 am
1 stop6h 25m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
Quickest round-trip
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Sun 1/17
7:17 pm-12:26 am
1 stop5h 09m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Thu 10/29
8:00 pm-9:10 pm
1 stop25h 10m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$232
LafayetteDes Moines
LFT Lafayette Regional - DSM Des Moines
LFTDSM
Lafayette Regional
Sat 12/12
6:07 am-4:49 pm
2 stops10h 42m
Des Moines
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$289
New OrleansDes Moines
MSY New Orleans Louis Armstrong - DSM Des Moines
MSYDSM
New Orleans Louis Armstrong
Wed 12/23
6:05 pm-11:30 pm
1 stop5h 25m
Des Moines
Wed 12/30
7:10 pm-12:40 am
1 stop5h 30m
$325
LafayetteDes Moines
LFT Lafayette Regional - DSM Des Moines
LFTDSM
Lafayette Regional
Thu 11/12
5:23 pm-11:05 pm
1 stop5h 42m
Des Moines
Mon 11/16
3:31 pm-10:54 pm
1 stop7h 23m
$339
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Louisiana to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisiana with our price prediction graph.
LFT-DSM
SHV-DSM
BTR-DSM
LCH-DSM
MSY-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Des Moines
USLA-DSM
LFT-DSM
SHV-DSM
BTR-DSM
LCH-DSM
What is the cheapest month to book a flight from Louisiana to Des Moines?
Currently, March is the cheapest month in which you can book a flight from Louisiana to Des Moines (average of $290). Flying from Louisiana to Des Moines in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Louisiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Louisiana to Des Moines
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Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 16, 2026.
Search flights from Louisiana to Des Moines by cabin class
Find flights from Louisiana to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisiana and Des Moines flights
Browse other Louisiana and Des Moines flight options. Last updated on October 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisiana to Des Moines flights
Consider these flights traveling from Louisiana to Des Moines.
Top 3 airlines flying from Louisiana to Des Moines
Discover the top 3 airlines that operate flights from Louisiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$506 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$444 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$406 | FlexibilityNo cancel fee | On-time69% |