$330+ Cheap flights from Des Moines (DSM) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDQ
Ιουλ 11 — Ιουλ 181
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to Santo DomingoExplore the most affordable flight options available from Des Moines to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Ιούνιος 11, 2026.
Explore the most affordable flight options available from Des Moines to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Ιούνιος 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Πεμ 7/1612:18 pm
SDQ
- DSM
1 stop10h 09m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$598
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/2910:00 am
DSM
- SDQ
1 stop23h 53m
Multiple Airlines
Πεμ 8/612:18 pm
SDQ
- DSM
1 stop10h 13m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Κυρ 7/1912:18 pm
SDQ
- DSM
1 stop11h 29m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$638
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Πεμ 7/233:37 pm
DSM
- SDQ
1 stop18h 26m
Multiple Airlines
Πεμ 7/3012:18 pm
SDQ
- DSM
1 stop10h 09m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$647
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/264:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Κυρ 8/212:18 pm
SDQ
- DSM
1 stop11h 29m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$652
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Δευ 7/136:37 pm
DSM
- SDQ
1 stop17h 40m
Delta
Παρ 7/172:42 pm
SDQ
- DSM
1 stop8h 47m
Delta
Deal found 6/7![Delta logo]()
$670
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/81:04 pm
DSM
- SDQ
1 stop22h 53m
American Airlines
Τετ 7/151:57 pm
SDQ
- DSM
1 stop9h 07m
American Airlines
Deal found 6/8![American Airlines logo]()
$671
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Σαβ 7/1110:54 am
DSM
- SDQ
2 stops25h 23m
Delta
Πεμ 7/166:05 am
SDQ
- DSM
2 stops29h 40m
Delta
Deal found 6/7![Delta logo]()
$675
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Δευ 7/136:37 pm
DSM
- SDQ
1 stop17h 40m
Delta
Σαβ 7/187:35 pm
SDQ
- DSM
2 stops23h 17m
Delta
Deal found 6/7![Delta logo]()
$680
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Σαβ 7/1110:54 am
DSM
- SDQ
2 stops25h 23m
Delta
Σαβ 7/187:35 pm
SDQ
- DSM
2 stops23h 17m
Delta
Deal found 6/7![Delta logo]()
$685
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Παρ 7/176:10 am
SDQ
- DSM
1 stop8h 40m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$687
Best flights from Des Moines to Santo DomingoDiscover carefully curated flight deals from Des Moines to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Ιούνιος 11, 2026.
Discover carefully curated flight deals from Des Moines to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Ιούνιος 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/2910:00 am
DSM
- SDQ
1 stop23h 53m
Multiple Airlines
Πεμ 8/612:18 pm
SDQ
- DSM
1 stop10h 13m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$627
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 7/76:30 am
DSM
- SDQ
2 stops13h 55m
American Airlines
Τρι 7/217:00 am
SDQ
- DSM
2 stops14h 51m
American Airlines
Deal found 6/11![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Δευ 7/136:37 pm
DSM
- SDQ
1 stop17h 40m
Delta
Τετ 7/152:42 pm
SDQ
- DSM
1 stop8h 47m
Delta
Deal found 6/7![Delta logo]()
$745
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/2910:00 am
DSM
- SDQ
1 stop23h 53m
Multiple Airlines
Τετ 8/512:41 pm
SDQ
- DSM
2 stops35h 38m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/125:32 pm
DSM
- SDQ
2 stops18h 45m
Delta
Παρ 7/177:35 pm
SDQ
- DSM
2 stops16h 10m
Delta
Deal found 6/7![Delta logo]()
$750
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/291:04 pm
DSM
- SDQ
1 stop22h 53m
American Airlines
Τετ 8/52:00 pm
SDQ
- DSM
1 stop9h 06m
American Airlines
Deal found 6/8![American Airlines logo]()
$757
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 7/145:41 am
DSM
- SDQ
1 stop6h 36m
Delta
Τετ 7/152:42 pm
SDQ
- DSM
2 stops20h 03m
Delta
Deal found 6/7![Delta logo]()
$750
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/263:59 pm
DSM
- SDQ
2 stops23h 30m
Multiple Airlines
Κυρ 8/212:18 pm
SDQ
- DSM
1 stop11h 29m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$753
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/298:50 pm
DSM
- SDQ
2 stops17h 34m
American Airlines
Πεμ 8/62:22 pm
SDQ
- DSM
2 stops20h 34m
American Airlines
Deal found 6/6![American Airlines logo]()
$769
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 7/145:41 am
DSM
- SDQ
1 stop6h 36m
Delta
Σαβ 7/187:35 pm
SDQ
- DSM
2 stops16h 10m
Delta
Deal found 6/7![Delta logo]()
$755
Last-minute flights from Des Moines to Santo DomingoDiscover last-minute flight deals from Des Moines to Santo Domingo. Data last updated Ιούνιος 11, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Santo Domingo. Data last updated Ιούνιος 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/81:04 pm
DSM
- SDQ
1 stop22h 53m
American Airlines
Τετ 7/151:57 pm
SDQ
- DSM
1 stop9h 07m
American Airlines
Deal found 6/8![American Airlines logo]()
$671
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Σαβ 7/115:32 pm
DSM
- SDQ
2 stops18h 45m
Delta
Τετ 7/152:42 pm
SDQ
- DSM
2 stops20h 03m
Delta
Deal found 6/7![Delta logo]()
$675
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Σαβ 7/1110:54 am
DSM
- SDQ
2 stops25h 23m
Delta
Σαβ 7/187:35 pm
SDQ
- DSM
2 stops23h 17m
Delta
Deal found 6/7![Delta logo]()
$685
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Πεμ 7/1612:18 pm
SDQ
- DSM
1 stop10h 09m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$598
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Κυρ 7/1912:18 pm
SDQ
- DSM
1 stop11h 29m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$638
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/124:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Παρ 7/176:10 am
SDQ
- DSM
1 stop8h 40m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$687
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Δευ 7/136:37 pm
DSM
- SDQ
1 stop17h 40m
Delta
Παρ 7/172:42 pm
SDQ
- DSM
1 stop8h 47m
Delta
Deal found 6/7![Delta logo]()
$670
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Δευ 7/136:37 pm
DSM
- SDQ
1 stop17h 40m
Delta
Σαβ 7/187:35 pm
SDQ
- DSM
2 stops23h 17m
Delta
Deal found 6/7![Delta logo]()
$680
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Πεμ 7/233:37 pm
DSM
- SDQ
1 stop18h 26m
Multiple Airlines
Πεμ 7/3012:18 pm
SDQ
- DSM
1 stop10h 09m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$647
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Κυρ 7/264:57 pm
DSM
- SDQ
1 stop17h 06m
Multiple Airlines
Κυρ 8/212:18 pm
SDQ
- DSM
1 stop11h 29m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$652
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/2910:00 am
DSM
- SDQ
1 stop23h 53m
Multiple Airlines
Πεμ 8/612:18 pm
SDQ
- DSM
1 stop10h 13m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$627
One-way flights from Des Moines to Santo DomingoSearch for one-way flight options from Des Moines to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated Ιούνιος 11, 2026.
Search for one-way flight options from Des Moines to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated Ιούνιος 11, 2026.
This Trip.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Πεμ 7/23:37 pm
DSM
- SDQ
1 stop18h 29m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/292:19 pm
DSM
- SDQ
2 stops31h 53m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 7/76:30 am
DSM
- SDQ
2 stops13h 55m
American Airlines
Deal found 6/7![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τετ 7/81:04 pm
DSM
- SDQ
1 stop22h 53m
American Airlines
Deal found 6/8![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 6/304:48 pm
DSM
- SDQ
2 stops15h 36m
American Airlines
Deal found 6/11![American Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 7/72:25 pm
DSM
- SDQ
3 stops26h 30m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$637
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Τρι 6/305:35 am
DSM
- SDQ
3 stops47h 24m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$667
Find flight deals from Des Moines to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated Ιούνιος 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $598 (Kiwi.com) |
One-way from | $330 (Trip.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Ιούνιος 11, 2026.
Use the filters below to find and compare flights from Des Moines to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τετ 7/29
10:00 am-10:53 am
1 stop23h 53m
Santo Domingo Las Americas
Πεμ 8/6
12:18 pm-9:31 pm
1 stop10h 13m
$627
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τρι 7/7
6:30 am-9:25 pm
2 stops13h 55m
Santo Domingo Las Americas
Τρι 7/21
7:00 am-8:51 pm
2 stops14h 51m
$710
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τετ 7/29
10:00 am-10:53 am
1 stop23h 53m
Santo Domingo Las Americas
Τετ 8/5
12:41 pm-11:19 pm
2 stops35h 38m
$710
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Δευ 7/13
6:37 pm-1:17 pm
1 stop17h 40m
Santo Domingo Las Americas
Τετ 7/15
2:42 pm-10:29 pm
1 stop8h 47m
$745
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Κυρ 7/12
5:32 pm-1:17 pm
2 stops18h 45m
Santo Domingo Las Americas
Παρ 7/17
7:35 pm-10:45 am
2 stops16h 10m
$750
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τρι 7/14
5:41 am-1:17 pm
1 stop6h 36m
Santo Domingo Las Americas
Τετ 7/15
2:42 pm-9:45 am
2 stops20h 03m
$750
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Κυρ 7/26
3:59 pm-4:29 pm
2 stops23h 30m
Santo Domingo Las Americas
Κυρ 8/2
12:18 pm-10:47 pm
1 stop11h 29m
$753
Quickest round-trip
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τρι 7/14
5:41 am-1:17 pm
1 stop6h 36m
Santo Domingo Las Americas
Σαβ 7/18
7:35 pm-10:45 am
2 stops16h 10m
$755
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τετ 7/29
1:04 pm-12:57 pm
1 stop22h 53m
Santo Domingo Las Americas
Τετ 8/5
2:00 pm-10:06 pm
1 stop9h 06m
$757
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Τετ 7/29
8:50 pm-3:24 pm
2 stops17h 34m
Santo Domingo Las Americas
Πεμ 8/6
2:22 pm-9:56 am
2 stops20h 34m
$769
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Santo Domingo in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Des Moines with our price prediction graph.
DSM-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated Ιούνιος 11, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Des Moines to Santo Domingo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Comfort
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Des Moines and Santo Domingo flights
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Top 2 airlines flying from Des Moines to Santo Domingo
Discover the top 2 airlines that operate flights from Des Moines to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Ιούνιος 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$514 | Average$574 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$613 | Average$643 | FlexibilityNo cancel fee | On-time71% |