$122+ Cheap flights from North Carolina to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from North Carolina to Des MoinesExplore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:07 am -
2 stops11h 55m
Sun 11/18:00 am -
1 stop24h 11m
Deal found 9/8![Multiple Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:55 am -
1 stop5h 54m
Tue 10/65:35 am -
1 stop4h 19m
Deal found 9/9![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:37 pm -
1 stop22h 05m
Sun 10/258:00 am -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:30 pm -
1 stop5h 25m
Mon 11/95:29 pm -
1 stop5h 15m
Deal found 9/9![Delta logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am -
1 stop13h 31m
Sun 10/41:37 pm -
1 stop7h 13m
Deal found 9/8![Allegiant Air logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:47 pm -
1 stop7h 25m
Sat 10/102:01 pm -
1 stop6h 53m
Deal found 9/5![American Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:47 pm -
2 stops9h 39m
Mon 11/1611:09 am -
1 stop4h 22m
Deal found 9/8![American Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:37 pm -
1 stop22h 05m
Sun 10/188:43 am -
1 stop22h 49m
Deal found 9/9![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:46 pm -
1 stop11h 08m
Mon 11/92:41 pm -
1 stop17h 27m
Deal found 9/6![Multiple Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:37 pm -
1 stop22h 05m
Mon 10/269:11 pm -
2 stops12h 46m
Deal found 9/8![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:25 pm -
1 stop5h 49m
Mon 11/95:29 pm -
1 stop5h 15m
Deal found 9/8![Delta logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:07 am -
1 stop26h 48m
Fri 10/93:04 pm -
1 stop17h 04m
Deal found 9/6![Multiple Airlines logo]()
$313
Best flights from North Carolina to Des MoinesDiscover carefully curated flight deals from North Carolina to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from North Carolina to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am -
1 stop13h 31m
Sun 10/41:37 pm -
1 stop7h 13m
Deal found 9/8![Allegiant Air logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:47 pm -
1 stop7h 25m
Sat 10/102:01 pm -
1 stop6h 53m
Deal found 9/5![American Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:25 pm -
1 stop5h 49m
Mon 11/95:29 pm -
1 stop5h 15m
Deal found 9/8![Delta logo]()
$313
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:06 pm -
1 stop6h 09m
Tue 10/68:00 am -
1 stop7h 03m
Deal found 9/8![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop5h 30m
Tue 11/36:00 am -
2 stops11h 25m
Deal found 9/9![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop4h 42m
Sat 10/1712:25 pm -
1 stop4h 18m
Deal found 9/9![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:00 am -
1 stop8h 20m
Mon 10/53:11 pm -
1 stop4h 38m
Deal found 9/4![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:55 pm -
2 stops9h 05m
Mon 10/54:30 pm -
2 stops5h 15m
Deal found 9/4![Southwest logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:08 am -
1 stop4h 56m
Mon 10/54:12 pm -
1 stop5h 40m
Deal found 9/9![American Airlines logo]()
$353
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:15 am -
1 stop6h 27m
Mon 10/126:54 pm -
1 stop4h 34m
Deal found 9/8![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop5h 31m
Mon 10/53:11 pm -
1 stop4h 38m
Deal found 9/5![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:10 pm -
2 stops7h 50m
Tue 12/153:30 pm -
1 stop4h 50m
Deal found 9/9![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:06 pm -
1 stop4h 51m
Mon 11/911:09 am -
1 stop4h 22m
Deal found 9/5![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
1 stop4h 42m
Sun 11/86:54 pm -
1 stop4h 51m
Deal found 9/9![Delta logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:06 am -
1 stop7h 22m
Mon 11/93:24 pm -
2 stops7h 19m
Deal found 9/9![United Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:08 am -
1 stop4h 56m
Sun 10/46:00 am -
2 stops8h 32m
Deal found 9/8![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:25 am -
2 stops11h 20m
Mon 11/25:25 am -
2 stops12h 25m
Deal found 9/9![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:19 pm -
1 stop5h 36m
Fri 10/303:24 pm -
1 stop5h 15m
Deal found 9/6![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:35 pm -
2 stops7h 40m
Fri 10/304:30 pm -
1 stop4h 15m
Deal found 9/6![Southwest logo]()
$400
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:08 am -
1 stop4h 56m
Mon 10/51:15 pm -
2 stops7h 47m
Deal found 9/8![American Airlines logo]()
$416
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:23 am -
2 stops12h 00m
Sun 10/188:00 am -
1 stop6h 10m
Deal found 9/7![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:48 pm -
1 stop4h 38m
Sat 10/105:39 am -
1 stop4h 57m
Deal found 9/9![Delta logo]()
$443
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:30 am -
1 stop5h 00m
Mon 11/96:40 am -
2 stops14h 25m
Deal found 9/5![Southwest logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:29 pm -
1 stop6h 45m
Mon 10/1911:22 am -
1 stop5h 05m
Deal found 9/7![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
1 stop5h 17m
Wed 11/111:27 pm -
2 stops9h 17m
Deal found 9/9![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:25 am -
2 stops11h 25m
Fri 10/305:10 am -
2 stops6h 50m
Deal found 9/8![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:00 am -
1 stop4h 46m
Wed 12/26:24 am -
1 stop5h 08m
Deal found 9/8![Delta logo]()
$461
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:01 pm -
1 stop7h 11m
Mon 9/281:30 pm -
1 stop6h 38m
Deal found 9/5![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
2 stops7h 34m
Mon 10/53:11 pm -
1 stop5h 35m
Deal found 9/9![United Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:05 am -
2 stops8h 10m
Sun 11/155:25 am -
2 stops14h 05m
Deal found 9/6![Southwest logo]()
$421
Last-minute flights from North Carolina to Des MoinesDiscover last-minute flight deals from North Carolina to Des Moines. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to Des Moines. Data last updated September 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 am -
1 stop5h 01m
Sat 10/38:00 am -
2 stops9h 34m
Deal found 9/9![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:55 am -
1 stop5h 54m
Tue 10/65:35 am -
1 stop4h 19m
Deal found 9/9![Delta logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am -
1 stop13h 31m
Sun 10/41:37 pm -
1 stop7h 13m
Deal found 9/8![Allegiant Air logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am -
1 stop13h 31m
Sun 10/46:40 am -
2 stops36h 17m
Deal found 9/7![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:47 pm -
1 stop7h 25m
Sat 10/102:01 pm -
1 stop6h 53m
Deal found 9/5![American Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:07 am -
1 stop26h 48m
Fri 10/93:04 pm -
1 stop17h 04m
Deal found 9/6![Multiple Airlines logo]()
$313
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:20 am -
1 stop5h 22m
Thu 10/156:54 pm -
1 stop4h 34m
Deal found 9/9![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:37 pm -
1 stop22h 05m
Sun 10/188:43 am -
1 stop22h 49m
Deal found 9/9![Multiple Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop4h 42m
Sat 10/1712:25 pm -
1 stop4h 18m
Deal found 9/9![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:37 pm -
1 stop22h 05m
Sun 10/258:00 am -
1 stop23h 32m
Deal found 9/8![Multiple Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:37 pm -
1 stop22h 05m
Mon 10/269:11 pm -
2 stops12h 46m
Deal found 9/8![Multiple Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:07 am -
2 stops11h 55m
Sun 11/18:00 am -
1 stop24h 11m
Deal found 9/8![Multiple Airlines logo]()
$274
One-way flights from North Carolina to Des MoinesSearch for one-way flight options from North Carolina to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from North Carolina to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:26 pm -
3 stops46h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:37 pm -
1 stop22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$136
This CheapOair deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:47 pm -
1 stop27h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:51 pm -
1 stop27h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:37 pm -
1 stop20h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$154
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:25 pm -
1 stop6h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$159
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:54 pm -
1 stop24h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:13 pm -
2 stops32h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$165
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
2 stops9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:50 pm -
1 stop4h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$184
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:05 am -
1 stop5h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$186
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:48 pm -
1 stop6h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$196
Find flight deals from North Carolina to Des Moines
Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (Kiwi.com) |
One-way from | $122 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $391 |
Good round-trip deal | $481 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighDes Moines
RDU Raleigh-Durham - DSM Des Moines
RDUDSM
Raleigh-Durham
Tue 10/13
5:26 pm-2:42 pm
3 stops46h 16m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$122
NorfolkDes Moines
ORF Norfolk - DSM Des Moines
ORFDSM
Norfolk
Mon 10/26
5:25 pm-10:33 pm
1 stop6h 08m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$159
RaleighDes Moines
RDU Raleigh-Durham - DSM Des Moines
RDUDSM
Raleigh-Durham
Tue 10/13
6:00 am-2:15 pm
2 stops9h 15m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$168
CharlotteDes Moines
CLT Charlotte Douglas - DSM Des Moines
CLTDSM
Charlotte Douglas
Mon 11/9
7:00 pm-11:00 pm
1 stop5h 00m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
Quickest round-trip
CharlotteDes Moines
CLT Charlotte Douglas - DSM Des Moines
CLTDSM
Charlotte Douglas
Tue 12/8
6:50 pm-10:00 pm
1 stop4h 10m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$179
KnoxvilleDes Moines
TYS Knoxville McGhee Tyson - DSM Des Moines
TYSDSM
Knoxville McGhee Tyson
Sun 11/22
8:50 pm-12:19 am
1 stop4h 29m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$184
CharlotteDes Moines
CLT Charlotte Douglas - DSM Des Moines
CLTDSM
Charlotte Douglas
Mon 12/7
3:10 pm-10:00 pm
2 stops7h 50m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$184
RaleighDes Moines
RDU Raleigh-Durham - DSM Des Moines
RDUDSM
Raleigh-Durham
Fri 12/25
8:05 am-12:41 pm
1 stop5h 36m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$186
CharlotteDes Moines
CLT Charlotte Douglas - DSM Des Moines
CLTDSM
Charlotte Douglas
Thu 10/8
7:40 am-11:10 am
1 stop4h 30m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$193
RaleighDes Moines
RDU Raleigh-Durham - DSM Des Moines
RDUDSM
Raleigh-Durham
Tue 12/8
1:48 pm-6:56 pm
1 stop6h 08m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$196
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from North Carolina to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
RDU-DSM
ORF-DSM
CLT-DSM
TYS-DSM
GSO-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to Des Moines
USNC-DSM
RDU-DSM
ORF-DSM
CLT-DSM
TYS-DSM
What is the cheapest month to book a flight from North Carolina to Des Moines?
Currently, January is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $338). Flying from North Carolina to Des Moines in August is currently the most expensive (average of $482). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from NC to DSM?
Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
It’s typically best to fly out from North Carolina to Des Moines in the afternoon. Doing so could potentially save you 11% on the flight price compared to flying in the morning, which is usually more expensive.
How much does it cost to fly round-trip from North Carolina to Des Moines?
Airfare is below average for this route at the moment.
North Carolina to Des Moines flights typically cost between $349 and $493 in October.The cheapest round-trip price found within the last 5 days was $294 on Multiple Airlines (Oct 21-Oct 25).
Related info for your journey
Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Alternative routes for North Carolina to Des Moines
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Complete your trip
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Search flights from North Carolina to Des Moines by cabin class
Find flights from North Carolina to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
North Carolina and Des Moines flights
Browse other North Carolina and Des Moines flight options. Last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
North Carolina to Des Moines flights
Consider these flights traveling from North Carolina to Des Moines.
Top 4 airlines flying from North Carolina to Des Moines
Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$411 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$439 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$363 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$462 | FlexibilityNo cancel fee | On-time63% |