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Des Moines

$134+ Cheap flights from North Carolina to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from North Carolina to Des Moines

Cheapest flights from North Carolina to Des Moines
Explore the most affordable flight options available from North Carolina to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:21 pm
RDU
-
DSM
1 stop17h 33m
Multiple Airlines
Mon 10/52:04 pm
DSM
-
RDU
1 stop18h 04m
Multiple Airlines
Deal found 7/23$237
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:20 pm
RDU
-
DSM
2 stops28h 37m
Multiple Airlines
Mon 9/1410:05 am
DSM
-
RDU
1 stop22h 03m
Multiple Airlines
Deal found 7/23$242
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:00 am
TYS
-
DSM
1 stop13h 26m
Allegiant Air
Sun 8/301:55 pm
DSM
-
TYS
1 stop27h 10m
Allegiant Air
Deal found 7/23$263
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am
AVL
-
DSM
1 stop13h 31m
Multiple Airlines
Sun 10/46:40 am
DSM
-
AVL
2 stops14h 10m
Multiple Airlines
Deal found 7/26$270
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:00 am
AVL
-
DSM
1 stop13h 31m
Allegiant Air
Sun 10/43:33 pm
DSM
-
AVL
1 stop20h 19m
Allegiant Air
Deal found 7/26$271
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:38 pm
CLT
-
DSM
2 stops21h 31m
Multiple Airlines
Tue 8/1812:53 pm
DSM
-
CLT
1 stop18h 08m
Multiple Airlines
Deal found 7/24$274
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:35 pm
RDU
-
DSM
1 stop5h 44m
Multiple Airlines
Mon 8/176:07 pm
DSM
-
RDU
1 stop26h 08m
Multiple Airlines
Deal found 7/24$277
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:37 pm
ILM
-
DSM
1 stop6h 36m
Multiple Airlines
Sun 10/183:54 pm
DSM
-
ILM
1 stop27h 04m
Multiple Airlines
Deal found 7/24$281
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:54 pm
RDU
-
DSM
1 stop6h 03m
Multiple Airlines
Mon 9/1410:05 am
DSM
-
RDU
1 stop22h 03m
Multiple Airlines
Deal found 7/26$283
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:00 am
TYS
-
DSM
2 stops37h 48m
Multiple Airlines
Sun 8/301:55 pm
DSM
-
TYS
1 stop27h 10m
Multiple Airlines
Deal found 7/26$286
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am
TYS
-
DSM
1 stop6h 06m
Delta
Tue 9/226:54 pm
DSM
-
TYS
1 stop4h 01m
Delta
Deal found 7/28$287
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:05 am
RDU
-
DSM
2 stops14h 52m
Multiple Airlines
Sun 9/61:58 pm
DSM
-
RDU
1 stop17h 55m
Multiple Airlines
Deal found 7/24$299

Find flight deals from North Carolina to Des Moines

Keep the following information in mind while searching for North Carolina to Des Moines flight deals. Data was last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$237
(Kiwi.com)

One-way from

$134
(Kiwi.com)

Popular in

February

Cheapest in

May

Average price

$438

Good round-trip deal

$471 or less

Good one-way deal

$389 or less
Provider with most accurate pricing for Raleigh-Durham-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Des Moines flights.
Search Deals
From North Carolina to Des Moines
Search Deals
One-way flight from North Carolina to Des Moines
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals
Price to beat on a round-trip flight from North Carolina to Des Moines.
Search Deals
Price to beat on a one-way flight from North Carolina to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from North Carolina to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 8/28

9:00 am-9:26 pm

1 stop13h 26m

Des Moines

Sun 8/30

1:55 pm-6:05 pm

1 stop27h 10m

$263

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 10/2

4:37 pm-10:13 pm

1 stop6h 36m

Des Moines

Sun 10/18

3:54 pm-7:58 pm

1 stop27h 04m

$281

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Thu 9/17

5:40 am-10:46 am

1 stop6h 06m

Des Moines

Tue 9/22

6:54 pm-11:55 pm

1 stop4h 01m

$287

AshevilleDes Moines

AVL - DSM

AVLDSM

Asheville Regional

Fri 9/18

6:34 pm-12:04 am

1 stop6h 30m

Des Moines

Mon 9/21

4:14 pm-11:07 pm

1 stop5h 53m

$319

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Wed 9/30

8:05 am-11:50 am

1 stop4h 45m

Des Moines

Tue 10/6

5:35 am-10:40 am

1 stop4h 05m

$321
Quickest round-trip

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Mon 8/24

8:10 am-11:25 am

1 stop4h 15m

Des Moines

Mon 8/31

5:40 am-11:10 am

1 stop4h 30m

$321

KnoxvilleDes Moines

TYS - DSM

TYSDSM

Knoxville McGhee Tyson

Fri 9/4

7:00 am-10:26 am

1 stop4h 26m

Des Moines

Tue 9/8

6:00 am-2:37 pm

2 stops7h 37m

$323

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Fri 8/28

6:40 am-12:20 pm

1 stop6h 40m

Des Moines

Sun 8/30

6:00 am-2:14 pm

2 stops7h 14m

$324

GreensboroDes Moines

GSO - DSM

GSODSM

Greensboro/H. Point

Thu 8/27

6:40 am-10:26 am

1 stop4h 46m

Des Moines

Sun 8/30

6:00 am-2:14 pm

2 stops7h 14m

$324

RaleighDes Moines

RDU - DSM

RDUDSM

Raleigh-Durham

Wed 9/16

11:45 am-4:48 pm

1 stop6h 03m

Des Moines

Tue 9/22

10:20 am-5:55 pm

1 stop6h 35m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from North Carolina to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Des Moines

What is the cheapest month to book a flight from North Carolina to Des Moines?

Currently, January is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $338). Flying from North Carolina to Des Moines in June is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to DSM?

Find hourly flight availability from North Carolina to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2026.

It’s typically best to fly out from North Carolina to Des Moines in the afternoon. Doing so could potentially save you 15% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from North Carolina to Des Moines?

Airfare is below average for this route at the moment.
North Carolina to Des Moines flights typically cost between $406 and $531 in August.
The cheapest round-trip price found within the last 5 days was $274 on Multiple Airlines (Aug 15-Aug 18).

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from North Carolina?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from North Carolina to Des Moines.

  • How popular is this North Carolina to Des Moines flight route?

    This flight path from North Carolina to Des Moines was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from North Carolina to Des Moines?

    A quick flight from North Carolina to Des Moines can take about 6h 06m. Allegiant Air provides one of the quickest options available for as low as $287. Airlines will cover a distance of 654 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from North Carolina to Des Moines one-way?

    $92 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $135 and $153, respectively.

  • What are the most popular routes from North Carolina to Des Moines?

    When deciding which route to take from North Carolina to Des Moines consider Charlotte Douglas - Des Moines, Raleigh-Durham - Des Moines or Myrtle Beach Intl - Des Moines as they are the most popular.

  • What are the cheapest flights from North Carolina to Des Moines?

    Looking for the cheapest flight from North Carolina to Des Moines? While on average our users pay $488, our data indicates the cheapest price to be $376. The most popular route (Charlotte Douglas - Des Moines), is priced around $321.

  • Can I find deals for flights from North Carolina to Des Moines that include hotel bookings?

    Yes. In addition to deals on North Carolina to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Des Moines.

  • Can I find deals for business class flights from North Carolina to Des Moines?

    Yes. Cheapflights offers flight deals from North Carolina to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Des Moines?

    Currently, January is the cheapest month in which you can book a flight from North Carolina to Des Moines (average of $338). Flying from North Carolina to Des Moines in June is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for North Carolina to Des Moines

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Top 4 airlines flying from North Carolina to Des Moines

Discover the top 4 airlines that operate flights from North Carolina to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$401FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$414FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$363FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$288Average$433FlexibilityNo cancel feeOn-time63%

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